CN101332246B - Traditional Chinese medicine preparation for treating coronary heart disease and angina - Google Patents

Abstract

The invention relates to a traditional Chinese medicine preparation for curing coronary heart disease and angina which is prepared by the following raw materials according to parts by weight: 18-22 parts of salvia miltiorrhiza, 4-6 parts of Sanchi, 17-23 parts of rubefacient, 13-18 parts of dalbergia wood, 13-18 parts of rhizoma corydalis, 7-11 parts of safflower, 18-22 parts of fleece-flower root, 25-35 parts of caulis spatholobi, 18-22 parts of myrrh, 13-17 parts of ginseng, 13-17 parts of cinnamon, 18-22 parts of epimedium, 4-6 parts of hairy deerhorn, 11-15 parts of glossy ganoderma, 7-9 parts of aweto, 12-18 parts of hemlock parsley, 8-12 parts of peach kernel, 13-17 parts of olibanum, 4-6 parts of scorpion, 4-6 of chilopod, 12-17 parts of the root bark of the peony tree. The preparation has the efficacy of activating Yang and removing obstruction and eliminating phlegm for resuscitation, and is suitable for relieving obstruction of Qi in chest, thoracic pain involving the back, serious pain and tesshin, cough, plenty sputum and breathless , tachycardia. 96 cases of the coronary heat disease are cured by the invention. 85 cases among the 96 cases have obvious effect, while 11 cases have no effect. The total effective rate is 88 percent. 87 cases are followed after the medicine is stopped eating for three months, which have no recurrence.

Description

Treatment coronary heart disease and anginal Chinese medicine preparation

Technical field

The invention belongs to a kind of pharmaceutical product, particularly a kind of coronary heart disease and anginal Chinese medicine preparation for the treatment of.

Background technology

Coronary heart disease is the abbreviation of coronary atherosclerotic heart disease.Being meant the blood vessel of supplying with the heart nutrient substance---serious atherosis or spasm takes place in coronary artery, make coronary stricture or obstruction, and thrombosis causes obliteration, causes a kind of heart disease of myocardial ischemia-anoxemia or infraction, also claims ischemic heart desease.Coronary heart disease is the common type that atherosclerosis causes organ lesion, also is the commonly encountered diseases of harm middle-aged and elderly people health.Degree and number that the generation of primary disease and coronary atherosclerosis are narrow have substantial connection, though the coronary atherosclerosis of minority young patient is not serious, even do not take place atherosisly, also can fall ill.Though also have some old people's coronary atherosclerotics narrow more serious, coronary heart disease clinical manifestations such as chest pain, cardiopalmus might not all be arranged.Therefore, cause of coronary heart disease mechanism is very complicated, as a whole, sees with organic more.Also multiple being born in of coronary vasospasm has atherosis coronary artery.

ACA comprises following several performance clinically:

1, sudden death.2, acute myocardial infarction.3, angina pectoris.4, acute left heart dysfunction, pulmonary edema.5, acute arrhythmia such as atrial fibrillation, multi-source pleiomorphism ventricular premature contraction, ventricular tachycardia, chamber quiver, severe sinus bradycardia, advanced A-V block etc.6, owing to acute myocardial ischemia, cardiac output can not cause the paroxysmal hypotension completely, faint.7, silent myocardial ischemia etc.The most serious in the above-mentioned performance with sudden death and two types of acute myocardial infarction.

Primary disease mostly occurred after 40 years old, and the male is more than the women, and the brain worker is more than physical labourer, and average prevalence is about 6.49%, and prevalence increases with the growth at age.Along with the influence of the life style of higher fatty acid, fast food, fast pace, high pressure, prevalence of coronary heart disease is the trend that rises year by year, and sicken age is tending towards rejuvenation.

Coronary heart disease has become the huge killer who has a strong impact on human health, does not have specific medicament at present for this disease treatment.

Summary of the invention

The object of the invention provides a kind of Chinese medicine preparation for the treatment of coronary heart disease.

Angina pectoris belongs to categories such as Chinese medicine " thoracic obstruction ", " angina pectoris ", " precordial pain with cold limbs ", " cardiopalmus ", and the traditional Chinese medical science is thought the generation of primary disease, many and inward invasion of pathogenic cold, and improper diet, factors such as disorder of emotion, body deficiency due to old age are relevant.As far back as " the Lei Zheng Zhi Cai thoracic obstruction " cloud: " thoracic obstruction, weakened YANG QI is not transported in the heart, for a long time then the yin subjugating yang position and be the numbness knot also ".It is main that Chinese traditional treatment coronary heart disease adopts blood circulation promoting and blood stasis dispelling, aromatic herbs activating YANG, supplementing QI and nourishing YIN, soothing the liver regulating QI etc. mostly, helps angry blood, and the capable then blood of gas is capable.

According to above theory, the present invention treats coronary heart disease and anginal Chinese medicine preparation, is to make with following weight portion raw material of Chinese medicine:

Radix Salviae Miltiorrhizae 18-22, Radix Notoginseng 4-6, Radix Paeoniae Rubra 17-23, Lignum Dalbergiae Odoriferae 13-18, Rhizoma Corydalis 13-18, Flos Carthami 7-11, Radix Polygoni Multiflori 18-22, Caulis Spatholobi 25-35, Myrrha 18-22, Radix Ginseng 13-17, Cortex Cinnamomi 13-17, Herba Epimedii 18-22, Cornu Cervi Pantotrichum 4-6, Ganoderma 11-15, Cordyceps 7-9, Rhizoma Chuanxiong 12-18, Semen Persicae 8-12, Olibanum 13-17, Scorpio 4-6, Scolopendra 4-6, Cortex Moutan 12-17.

The preferential prescription of recommending of the present invention:

Radix Salviae Miltiorrhizae 20, Radix Notoginseng 5, Radix Paeoniae Rubra 20, Lignum Dalbergiae Odoriferae 15, Rhizoma Corydalis 15, Flos Carthami 9, Radix Polygoni Multiflori 20, Caulis Spatholobi 30, Myrrha 20, Radix Ginseng 15, Cortex Cinnamomi 15, Herba Epimedii 20, Cornu Cervi Pantotrichum 5, Ganoderma 13, Cordyceps 8, Rhizoma Chuanxiong 15, Semen Persicae 10, Olibanum 15, Scorpio 5, Scolopendra 5, Cortex Moutan 15.

Side of the present invention separates:

Radix Notoginseng-hemostasia and dissipation blood stasis, subduing swelling and relieving pain;

Radix Salviae Miltiorrhizae-blood circulation promoting and blood stasis dispelling, relieving restlessness is calmed the nerves, reducing swelling and alleviating pain;

Radix Paeoniae Rubra-removing heat from blood and promoting blood circulation, stasis-dispelling and pain-killing, liver heat removing and eyesight improving;

Lignum Dalbergiae Odoriferae-clots absorbing pain relieving analgesic therapy;

Rhizoma Corydalis-promoting blood circulation to remove blood stasis, the promoting the circulation of QI pain relieving;

Flos Carthami-promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing;

Skin ulcer, preventing the attack (or recurrence) of malaria (give birth to and use) are controlled in Radix Polygoni Multiflori-invigorating the liver and kidney, benefiting essence-blood, relieving constipation;

Caulis Spatholobi-promoting the circulation of blood is enriched blood, relaxing muscles and tendons and activating QI and blood in the collateral;

Myrrha-promoting blood circulation and stopping pain,, detumescence and promoting granulation;

Radix Ginseng-QI invigorating emergency treatment of collapse is mended strengthening spleen and lung, promoting the production of body fluid to quench thirst, the Fructus Alpiniae Oxyphyllae of calming the nerves;

Cortex Cinnamomi-warming middle-JIAO YANG invigorating, dispersing cold for relieving pain;

Herba Epimedii-kidney invigorating and YANG supporting, expelling wind and removing dampness, blood pressure lowering, antitussive, eliminate the phlegm, relieving asthma;

Cornu Cervi Pantotrichum-kidney-replenishing, benefiting essence-blood, bone and muscle strengthening;

Ganoderma-invigorating QI and tranquilization, relieving cough and asthma;

Cordyceps-nourishing the lung and kidney, hemostasis and phlegm;

Rhizoma Chuanxiong-blood-activating and qi-promoting, wind-expelling pain-stopping;

Semen Persicae-removing blood stasis with potent drugs promoting the circulation of blood is moisturized laxation;

Olibanum-promoting blood circulation and stopping pain, detumescence and promoting granulation, secondary muscle is active;

Scorpio-relieving spasm by subduing liver-wind, activating collaterals to relieve pain, toxin expelling is treated skin ulcer;

Scolopendra-relieving spasm by subduing liver-wind, toxin expelling is treated skin ulcer;

Radix Paeoniae Rubra-removing heat from blood and promoting blood circulation, stasis-dispelling and pain-killing, liver heat removing and eyesight improving;

Cortex Moutan-clearing away heat and cooling blood, removing heat from the liver to lower the high blood pressure, activating blood circulation and dissipating blood stasis.

The present invention has activating YANG and eliminating stagnation, and the effect of the eliminating phlegm therapeutic method to keep the adverse QI flowing downwards adapts to the thoracic obstruction, chest pain radiating to the back, backache radiating to the heart, and cough, abundant expectoration are out of breath, tachycardia.Advantage is that compatibility is simple, and dosage is few, and each symptom of coronary heart disease is all produced effect.

The specific embodiment

Prescription 1 (unit: restrain, down together) Radix Salviae Miltiorrhizae 18, Radix Notoginseng 6, Radix Paeoniae Rubra 17, Lignum Dalbergiae Odoriferae 18, Rhizoma Corydalis 13, Flos Carthami 11, Radix Polygoni Multiflori 18, Caulis Spatholobi 35, Myrrha 18, Radix Ginseng 17, Cortex Cinnamomi 13, Herba Epimedii 22, Cornu Cervi Pantotrichum 4, Ganoderma 15, Cordyceps 7, Rhizoma Chuanxiong 18, Semen Persicae 8, Olibanum 17, Scorpio 4, Scolopendra 6, Cortex Moutan 12.

Prescription 2: Radix Salviae Miltiorrhizae 20, Radix Notoginseng 5, Radix Paeoniae Rubra 20, Lignum Dalbergiae Odoriferae 15, Rhizoma Corydalis 15, Flos Carthami 9, Radix Polygoni Multiflori 20, Caulis Spatholobi 30, Myrrha 20, Radix Ginseng 15, Cortex Cinnamomi 15, Herba Epimedii 20, Cornu Cervi Pantotrichum 5, Ganoderma 13, Cordyceps 8, Rhizoma Chuanxiong 15, Semen Persicae 10, Olibanum 15, Scorpio 5, Scolopendra 5, Cortex Moutan 15.

Prescription 3: Radix Salviae Miltiorrhizae 22, Radix Notoginseng 4, Radix Paeoniae Rubra 23, Lignum Dalbergiae Odoriferae 13, Rhizoma Corydalis 18, Flos Carthami 7, Radix Polygoni Multiflori 22, Caulis Spatholobi 25, Myrrha 22, Radix Ginseng 13, Cortex Cinnamomi 17, Herba Epimedii 18, Cornu Cervi Pantotrichum 6, Ganoderma 11, Cordyceps 9, Rhizoma Chuanxiong 12, Semen Persicae 12, Olibanum 13, Scorpio 6, Scolopendra 4, Cortex Moutan 17.

Above-mentioned prescription drug is crushed to 100 orders after mixing, and incapsulates sterilization and gets final product.

The present invention treats coronary heart disease 96 routine clinical summaries

Coronary heart disease is the commonly encountered diseases of middle-aged and elderly people, and frequently-occurring disease, this disease belong to Chinese medicine " thoracic obstruction ", " angina pectoris " category.Use preparation for treating coronary heart disease 96 examples of the present invention, obtain better curative effect, now be reported as follows:

1, the clinical data case is selected 96 examples, all by " coronary heart disease Chinese medical discrimination standard " execution of first national internal medicine academic conference cardiovascular diseases special interest group in 1980 " about the suggestion of coronary heart disease name and diagnostic criteria " and in October, 1 990 CAIM (Chinese Association Of Integrative Medicine) cardiovascular association revision, wherein male 59 examples, women 36 examples; At minimum 32 years old of age, maximum 71 years old, the course of disease is the longest 23 years, and was the shortest 0.5 year, 0.5～5 year 51 example wherein, 6～10 years 21 examples, 24 examples more than 20 years.Wherein coronary heart disease is with angina pectoris 67 examples

2, Therapeutic Method

2.1, basic side's medicine: adopt medicament capsule of the present invention, take every day 30 the gram, divide and take for three times.Two weeks is a course of treatment, general treatment 2-3 course of treatment, avoids exertion anger.

2.2, curative effect judging standard:

Studying forum " coronary heart disease efficacy assessment standard " according in JIUYUE, 1979 whole nation therapy of combining Chinese and Western medicine evaluates.

Produce effects: " breathe hard, pained transference cure or obviously alleviate, other double disease and electrocardiogram are stable or progressive to some extent.

Invalid: all diseases and electrocardiogram no change;

3, therapeutic effect

(1) with angina pectoris 67 examples, produce effects 59 examples, invalid 8 examples.

(2), quiver in other acute left heart dysfunction, pulmonary edema, acute arrhythmia such as atrial fibrillation, multi-source pleiomorphism ventricular premature contraction, ventricular tachycardia, chamber, severe sinus bradycardia etc. adds up to 29 examples, produce effects 26 examples, invalid 3 examples.

(3), add up to 96 examples, produce effects 85 examples, invalid 11 examples.

Treat all disease 96 examples of coronary heart disease, produce effects 85 examples, invalid 11 examples through the present invention.Total effective rate 88%.Follow up a case by regular visits to 87 examples in three months after the drug withdrawal, all do not have recurrence.

Claims (2)

1. treat coronary heart disease and anginal Chinese medicine preparation, it is characterized in that making with following weight portion raw material of Chinese medicine:

Radix Salviae Miltiorrhizae 18-22, Radix Notoginseng 4-6, Radix Paeoniae Rubra 17-23, Lignum Dalbergiae Odoriferae 13-18, Rhizoma Corydalis 13-18, Flos Carthami 7-11, Radix Polygoni Multiflori 18-22, Caulis Spatholobi 25-35, Myrrha 18-22, Radix Ginseng 13-17, Cortex Cinnamomi 13-17, Herba Epimedii 18-22, Cornu Cervi Pantotrichum 4-6, Ganoderma 11-15, Cordyceps 7-9, Rhizoma Chuanxiong 12-18, Semen Persicae 8-12, Olibanum 13-17, Scorpio 4-6, Scolopendra 4-6, Cortex Moutan 12-17.

2. treatment coronary heart disease according to claim 1 and anginal Chinese medicine preparation is characterized in that making with following weight portion raw material of Chinese medicine:

Radix Salviae Miltiorrhizae 20, Radix Notoginseng 5, Radix Paeoniae Rubra 20, Lignum Dalbergiae Odoriferae 15, Rhizoma Corydalis 15, Flos Carthami 9, Radix Polygoni Multiflori 20, Caulis Spatholobi 30, Myrrha 20, Radix Ginseng 15, Cortex Cinnamomi 15, Herba Epimedii 20, Cornu Cervi Pantotrichum 5, Ganoderma 13, Cordyceps 8, Rhizoma Chuanxiong 15, Semen Persicae 10, Olibanum 15, Scorpio 5, Scolopendra 5, Cortex Moutan 15.