CN101321767B - 用于专一性检测过亚硝酸根的试剂 - Google Patents

用于专一性检测过亚硝酸根的试剂 Download PDF

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CN101321767B
CN101321767B CN200680045462.9A CN200680045462A CN101321767B CN 101321767 B CN101321767 B CN 101321767B CN 200680045462 A CN200680045462 A CN 200680045462A CN 101321767 B CN101321767 B CN 101321767B
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hydrogen
alkyl
heptyl
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CN101321767A (zh
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D·扬
H·王
Z·孙
J·沈
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Versitech Ltd
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University of Hong Kong HKU
Versitech Ltd
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10Spiro-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/17Nitrogen containing

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CN200680045462.9A 2005-10-07 2006-08-25 用于专一性检测过亚硝酸根的试剂 Active CN101321767B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/245,529 US7705040B2 (en) 2005-10-07 2005-10-07 Reagents for highly specific detection of peroxynitrite
US11/245,529 2005-10-07
PCT/CN2006/002177 WO2007041923A1 (en) 2005-10-07 2006-08-25 Reagents for highly specific detection of peroxynitrite

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CN101321767A CN101321767A (zh) 2008-12-10
CN101321767B true CN101321767B (zh) 2012-02-08

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US (1) US7705040B2 (https=)
EP (1) EP1943254A4 (https=)
JP (1) JP2009510462A (https=)
CN (1) CN101321767B (https=)
AU (1) AU2006301818A1 (https=)
CA (1) CA2624598A1 (https=)
WO (1) WO2007041923A1 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8178669B2 (en) * 2005-11-14 2012-05-15 The University Of Tokyo Fluorescent probe for peroxynitrite
US7858598B2 (en) * 2007-03-12 2010-12-28 Morningside Ventures Limited & Versitech Limited Reagents for detection of hypochlorous acid
JPWO2009107769A1 (ja) * 2008-02-29 2011-07-07 国立大学法人 東京大学 活性酸素測定用試薬
US8795264B2 (en) * 2008-07-01 2014-08-05 Ralph Zipper Method for decreasing the size and/or changing the shape of pelvic tissues
US10743929B2 (en) * 2009-07-01 2020-08-18 Ralph Zipper Bulbous tipped surgical device and method for decreasing the size and/or changing the shape of pelvic tissues
US20110004203A1 (en) * 2009-07-01 2011-01-06 Ralph Zipper Laser Device and Method for Decreasing the Size and/or Changing the Shape of Pelvic Tissues
US20100081159A1 (en) * 2008-09-26 2010-04-01 Lebedeva Irina V Profiling reactive oxygen, nitrogen and halogen species
WO2012047212A1 (en) * 2010-10-06 2012-04-12 Hewlett-Packard Development Company, L.P. Modified bodipy dye matrix
KR101174585B1 (ko) 2011-04-11 2012-08-16 부산대학교 산학협력단 퍼옥시니트리트 검출용 바이오센서 및 이를 이용한 퍼옥시니트리트 검출방법
CN102702768B (zh) * 2012-06-04 2013-12-04 天津理工大学 一种新型红光bodipy荧光染料及其制备方法和应用
CN102898858B (zh) * 2012-10-19 2014-10-01 中国乐凯集团有限公司 一种3',6'-二甲氧基荧烷黄热敏染料的制备方法
US20150291628A1 (en) * 2013-01-28 2015-10-15 Council Of Scientific & Industrial Research Novel aza bodipy compound for the selective detection of nitrite ions in water and a process for preparation thereof
CN103145685B (zh) * 2013-03-20 2014-10-29 大连理工大学 一类荧光化合物和其在检测钌中的应用
CN103342720B (zh) * 2013-07-01 2015-08-26 南京大学 近红外bodipy类的羟基自由基探针及其合成方法和用途
HU231175B1 (hu) * 2015-12-04 2021-06-28 CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. Tetszőleges, előre meghatározott minőségű Latanoprostene bunod előállítása gravitációs kromatográfiával
GB2551567A (en) * 2016-06-23 2017-12-27 Sumitomo Chemical Co Method, composition and sensor
CN108732299B (zh) * 2018-06-01 2020-10-16 遵义医科大学 水质中亚硝酸盐的比色检测方法
JP2021155362A (ja) * 2020-03-27 2021-10-07 株式会社ナリス化粧品 ペルオキシナイトライト活性阻害方法および、ペルオキシナイトライト活性阻害剤のスクリーニング方法
CN114853779B (zh) * 2022-06-09 2023-11-10 南京工业大学 细胞及生物体内生物硫醇检测与特异性快速标记巯基蛋白质的荧光探针、制备方法及应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0654311B2 (ja) * 1986-10-28 1994-07-20 コニカ株式会社 亜硝酸イオンによる口臭測定用分析素子
US5185129A (en) * 1991-02-28 1993-02-09 President And Fellows Of Harvard College Ozone monitors
CN1222286C (zh) * 1994-05-13 2005-10-12 孟山都公司 过亚硝酸盐分解催化剂的应用方法及其药物组合物
US5729697A (en) * 1995-04-24 1998-03-17 International Business Machines Corporation Intelligent shopping cart
US6861262B2 (en) * 2000-03-03 2005-03-01 Quest Diagnostics Investments Incorporated Composition and method for detecting an adulterant in an aqueous sample
EP1260508B1 (en) * 2000-02-29 2010-04-14 Sekisui Medical Co., Ltd. Reagents for the quantitation of active oxygen
US7599855B2 (en) * 2001-02-13 2009-10-06 Lester Sussman System and method for a complete and convenient shopping experience
WO2004040296A1 (ja) 2002-10-16 2004-05-13 Daiichi Pure Chemicals Co., Ltd. パーオキシナイトライト測定用試薬
CN100427928C (zh) * 2005-01-17 2008-10-22 浙江大学 硝酸盐、亚硝酸盐快速测定试纸及其应用
US7389934B2 (en) * 2005-05-27 2008-06-24 International Business Machines Corporation On-demand point-of-sale scanner access

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Dan Yang, et. al..Regioselective Intramolecular Oxidation of Phenols and Anisoles by Dioxranes Generated in Situ.《Journal of Organic Chemistry》.2000,第65卷(第13期), *
John E. T. Corrie,et.al..Synthesis of Photoactivatable Fluorescein Derivatives Bearing Side Chains with Varying Properties.《Journal of Chemical Society-Perkin Transactions》.1995,第1卷(第16期), *
Yang Dan,et. al..A Highly Selective Fluorescent Probe for the Detection and Imaging of Peroxynitrite in Living Cells.《Journal of American Chemical Society》.2006,第128卷 *

Also Published As

Publication number Publication date
US7705040B2 (en) 2010-04-27
CA2624598A1 (en) 2007-04-19
AU2006301818A1 (en) 2007-04-19
EP1943254A4 (en) 2010-05-05
EP1943254A1 (en) 2008-07-16
JP2009510462A (ja) 2009-03-12
US20070082403A1 (en) 2007-04-12
CN101321767A (zh) 2008-12-10
WO2007041923A1 (en) 2007-04-19

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