CN101317963B - Traditional Chinese medicine for treating exogenous injury and ulcer and preparation method thereof - Google Patents
Traditional Chinese medicine for treating exogenous injury and ulcer and preparation method thereof Download PDFInfo
- Publication number
- CN101317963B CN101317963B CN2008103025077A CN200810302507A CN101317963B CN 101317963 B CN101317963 B CN 101317963B CN 2008103025077 A CN2008103025077 A CN 2008103025077A CN 200810302507 A CN200810302507 A CN 200810302507A CN 101317963 B CN101317963 B CN 101317963B
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- preparation
- ulcer
- micropowder
- portions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention discloses a Chinese medicine for curing trauma and ulcer and a preparation method thereof. The medicine is made from the raw materials with the following weight portions: 1 to 30 portions of chitin, 30 to 80 portions of marmor serpentinatum, 10 to 70 portions of hyacinth bletilla, 0.5 to 5 portions of hairyvein agrimony and 0.5 to 5 portions of callicarpone. The Chinese medicine provided by the present invention utilizes the organic molecule chitin and the inorganic mineral molecule marmor serpentinatum with positive charge to form 'electronic gel' and then stick variouspathogens and viruses, so that the pathogens and viruses lose vitality. The formed 'electronic gel' has very strong static attraction, thus forming a protective membrane on the trauma and having obvious hemostatic effect. The latex preparation is alkalescent and includes cations such as Mg<2+>, K<+>, Zn< 2+ > and H<+>, thus promoting the trauma heal. Therefore, the present invention is an external use medicine which takes physical reaction as the center with good hemostatic effect and sterilization and can rapidly heal the trauma. In addition, by internal application, the medicine can cure gastrointestinal ulcer and diarrhea with obvious curative effect, no toxic and side effect and no harm to the human body.
Description
Technical field
The present invention relates to injure Chinese medicine of ulcer and preparation method thereof outside a kind of the treatment, belong to technical field of traditional Chinese medicine pharmacy.
Background technology
China is the wushu cradle, and all there be the nostrum or the secret recipe of treatment daggers and swords wound in each school of martial arts circles in early days, but its most secret recipes are lost gradually.The pill for traumatic injuries class of curing wound in the Chinese patent medicine is in the majority, but all is oral medicine, plays blood circulation promoting and blood stasis dispelling.Being used for the hemostatic traumatic mainly is YUNNAN BAIYAO at present, and former being named as " cure-all " is that Qu Huanzhang succeeded in developing in 1902, apart from the present T﹠B.The effect of YUNNAN BAIYAO removing stasis to stop bleeding, promoting blood circulation and stopping pain, removing toxic substances and promoting subsidence of swelling is remarkable, but its germ-resistant effect relatively a little less than.Doctor trained in Western medicine is to general 70% ethanol, hydrogen peroxide and these the three kinds of wound disinfectant of iodine tincture of adopting of wound sterilizing, and sterilization effect is good, but can not stop blooding, and can not promote new cell growth; And common people are difficult to stand the unbearable pain of ethanol when stimulating wound, and people describe with the alcohol wash wound as above " cruel torture ".Over nearly 10 years, " bandage " circulates extensively in market, is mainly used in little wound, seals fresh wound with the iodine tincture gauze, seals in time can cicatrize a wound, if the amount of bleeding greatly then is difficult to prove effective.
The early stage fisherman in the North Sea, Guangxi often wears into Carapax Eriocheir sinensis fine powder treatment wound, and the effective ingredient in the Carapax Eriocheir sinensis is a chitin.Chitin is the unique a kind of Organic substance that has positive charge of nature, so chitin also is charged magnetic, can form glued membrane at the wound place, stops that antibacterial invades and prevent the generation of antibacterial.But list is treated wound with chitin, does not reach the effect of rapid healing, needs could strengthen its curative effect with other medical material compatibility.
Summary of the invention
Technical problem to be solved by this invention is: a kind of have simultaneously good hemostasis and bactericidal effect are provided, and the wound medication of energy rapid healing wound, this medicine is the external treatment wound not only, and treatment by oral administration of medicines gastroenteritic ulcer and dysentery diarrhoea.
Technical scheme of the present invention: injure the Chinese medicine of ulcer outside a kind of the treatment, according to listed as parts by weight, it is made for 0.5～5 part with 1～30 part of chitin, 30～80 parts of OPHICALCITUMs, 10～70 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 0.5～5 part of Herba Agrimoniae and Folium Callicarpae Formosanae.
Be preferably: according to listed as parts by weight, it is made for 0.5 part with 10 parts of chitins, 60 parts of OPHICALCITUMs, 29 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 0.5 part of Herba Agrimoniae and Folium Callicarpae Formosanae.
Described Chinese medicine preparation is powder, ointment, liquid preparation or patch.
The outer preparation method of Chinese medicine that injures ulcer of treatment is: take by weighing chitin 1～30 weight portion, OPHICALCITUM 30～80 weight portions, Pseudobulbus Bletillae (Rhizoma Bletillae) 10～70 weight portions, Herba Agrimoniae 0.5～5 weight portion and Folium Callicarpae Formosanae 0.5～5 weight portion, under 70～90 ℃ of conditions, dried 3～5 hours, be cooled to room temperature, wear into micropowder, sterilization is made various preparation then.
Preferred manufacturing procedure is: take by weighing chitin, OPHICALCITUM, Pseudobulbus Bletillae (Rhizoma Bletillae), Herba Agrimoniae and Folium Callicarpae Formosanae, place electric oven, oven dry is 4 hours under 80 ℃ of conditions, taking-up is cooled to room temperature, wear into 10～100 nano level micropowders with pneumatic grinding mill or ball mill, utilize high-pressure ozone storehouse sterilization, make powder then or further make ointment, emulsion formulations or patch.
Described ointment is made like this: the micropowder after the sterilization of cancellation poison, steeped 72 hours with the water logging of 5 times of micropowder weight, and fill, promptly.
Described emulsion formulations is made like this: the micropowder after the sterilization of cancellation poison, and the water of 20 times of micropowder weight of adding stirs, fill immediately, promptly.
Described patch is made like this: get the micropowder of 15 grams behind the sterilizations, add in the 100ml ethanol iodine tincture, after stirring gauze is placed in one and soaked 30～60 minutes, with the gauze oven drying at low temperature, tailor into fritter then, make bandage, promptly.
In the prescription of the present invention, chitin is a kind of organic magnetic body that extracts with chemical method from Carapax Eriocheir sinensis, and the macromole that has positive charge by thousands of nitrogenous polymerization polysaccharides are formed is one of principal agent; Two of principal agent is an OPHICALCITUM, and OPHICALCITUM is the mineral mixed type clay class Ore that the volcanic rock waste is deposited as, and reserves are abundant, and its chemical constituent is mainly aluminium magensium silicate, and crystallization is fine, and is positively charged between lattice layer, can Mg be arranged for the cation of exchange
2+, K
+, H
+, Na
+, Ca
2+, Zn
2+Deng.The OPHICALCITUM powder is met water and is paste, and its emulsion is an alkalescence.Put down in writing according to Compendium of Material Medica: " it is hemorrhage that OPHICALCITUM cures mainly incised wound, and spatulation applies and gets final product, and never suppurates; Control all damages of losing blood, the internal hemorrhage due to trauma corneal nebula; Its merit is removed stagnant blood specially in hemostasis." after above-mentioned two kinds of positively charged raw materials mix by a certain percentage; can form " electronic pastes " with very strong absorbability; because its unique electrostatic attraction; can form protecting film in the wound; haemostatic effect is obvious; can shorten clotting time, and can promote platelet counts to raise no rejection and anaphylaxis.
Chinese medicine of the present invention also has germ-resistant function, and can not sterilize as traumatic causes easily that just wound suppuration festers." treating the poisonous disease with poisonous drugs " is the popular feature of most of antibacterial.Every medicine that utilizes the sterilization of organic molecule such as alkaloids tends to produce infringement to human body.Chitin among the present invention and OPHICALCITUM constitute " electronic pastes ", bondings such as various bacteria such as staphylococcus aureus, Hemolytic streptococcus, dysentery bacterium, bacillus pyocyaneus, tetanolysin can be got up, and make it lose one's life power and are knocked out.
Chinese medicine of the present invention also can promote wound healing.If make human tissue cell's regeneration, need Mg
2+, K
+The pH value that enters lifting Cell sap in the cell Deng alkaline kation is 7.40, and this is one of fissional essential condition.The pH value of emulsion formulations of the present invention is 7.8～8.5, contains Mg
2+, K
+, H
+, Na
+, Ca
2+, Zn
2+Deng metal cation, can be the weakly alkaline environment that the affected part tissue provides normal physiological to need, help the repair damage position.And the condition of germ reproduction is a sour environment, also can effectively suppress the breeding of pathogenic bacteria under alkaline environment.
Oral medicinal herb of the present invention also can be cured gastroenteritic ulcer and dysentery diarrhoea.Behind the oral emulsion formulations of the present invention, can prevent the pathogenic bacteria intrusion, simultaneously the bacillus pyocyaneus on the focus, helicobacter pylori etc. be disposed because of " electronic pastes " effect forms protecting film on the gastrointestinal mucosa wall.Because of emulsion formulations is an alkalescence, help damaged tissues cell regeneration, repair damage location fast, ulcer surface is dwindled gradually up to rehabilitation.Maximum characteristics by physical action principle treatment ulcer are to have no side effect, and point out the gastric ulcer patient to take preparation or aluminium porcelain enamelling stomach medicine for a long time according to the medical expert, the easy damaged brain, influence memory.Treatment by Chinese herbs dysentery diarrheal pharmacology of the present invention is identical with the pharmacology of treatment gastroenteritic ulcer, and its emulsion formulations forms the electronic pastes protecting film in intestinal, and pathogenic bacterias such as dysentery bacterium are bondd by electronic pastes and lose physiologically active, excrete in company with feces; Weakly alkaline environment also is unfavorable for the breeding of pathogenic bacteria simultaneously.
Pseudobulbus Bletillae (Rhizoma Bletillae) in the prescription, Herba Agrimoniae and Folium Callicarpae Formosanae help out to hemostasis, sterilization etc. for assisting a ruler in governing a country medical material.Above-mentioned two flavor principal agents and three flavors are assisted a ruler in governing a country the mutual compatibility of medical material, Synergistic is played hemostasis, sterilization, antibacterial, the effect of repairing damage altogether, is used for treatment and the gastroenteritic ulcer and the treatment of dysentery diarrheal of various wounds, its effect is remarkable, and can reach the effect of rapid healing.
Compared with prior art, organic molecule chitin and inorganic mineral molecule OPHICALCITUM that Chinese medicine utilization of the present invention has positive charge constitute " electronic pastes ", multiple pathogenic bacteria and virus bonding can be got up, and make its power that loses one's life; Formed " electronic pastes " has very strong electrostatic attraction, can form protecting film in the wound, and haemostatic effect is obvious; Its emulsion formulations is an alkalescence, contains Mg
2+, K
+, Zn
2+, H
+Etc. cation, can promote wound healing.Therefore, the present invention is a kind of based on physical action, has good hemostasis and bactericidal effect simultaneously, the wound medication of energy rapid healing wound, gastroenteritic ulcer and the dysentery diarrhoea of also can treating for oral administration, it is evident in efficacy, do not have rejection and anaphylaxis, have no side effect, human body is not had injury.
The specific embodiment:
Embodiments of the invention 1: take by weighing chitin 10Kg, OPHICALCITUM powder 60Kg, Rhizoma Bletillae powder 29Kg, Herba Agrimoniae 0.5Kg and Folium Callicarpae Formosanae grass roots powder 0.5Kg, place electric oven, oven dry is 4 hours under 80 ℃ of conditions, taking-up is cooled to room temperature, wear into 10～100 nano level micropowders with pneumatic grinding mill, utilize high-pressure ozone storehouse sterilization; Micropowder after the sterilization was steeped 72 hours with the water logging of 5 times of weight, and fill promptly makes ointment.The said preparation external directly is coated with to put on the skin in the affected part during use and gets final product.
Embodiments of the invention 2: take by weighing chitin 1Kg, OPHICALCITUM powder 80Kg, Rhizoma Bletillae powder 10Kg, Herba Agrimoniae 5Kg and Folium Callicarpae Formosanae grass roots powder 0.5Kg, place electric oven, oven dry is 5 hours under 70 ℃ of conditions, taking-up is cooled to room temperature, wear into 10～100 nano level micropowders with ball mill, utilize high-pressure ozone storehouse sterilization; Micropowder after the sterilization adds the water of 20 times of weight, stirs, and fill immediately promptly makes emulsion formulations.Said preparation is oral administration both, but also external; 2-3 gram when for oral administration/time, 3 times/day; The outer time spent dips in taking liquid and is coated with to put on the skin in the affected part and gets final product.
Embodiments of the invention 3: take by weighing chitin 30Kg, OPHICALCITUM 30Kg, Pseudobulbus Bletillae (Rhizoma Bletillae) 70Kg, Herba Agrimoniae 0.5Kg and Folium Callicarpae Formosanae 5Kg, place electric oven, oven dry is 3 hours under 90 ℃ of conditions, taking-up is cooled to room temperature, wear into 10～100 nano level micropowders with pneumatic grinding mill, utilize high-pressure ozone storehouse sterilization; Micropowder after the sterilization is carried out packing, promptly makes powder.Said preparation is oral administration both, but also external; 2-3 gram when for oral administration/time, 3 times/day; The powder of getting it filled of outer time spent is coated on the affected part and gets final product.
Embodiments of the invention 4: take by weighing chitin 30Kg, OPHICALCITUM 80Kg, Pseudobulbus Bletillae (Rhizoma Bletillae) 70Kg, Herba Agrimoniae 5Kg and Folium Callicarpae Formosanae 5Kg, oven dry is 4 hours under 80 ℃ of conditions, is cooled to room temperature, wears into 10～100 nano level micropowders, sterilization with ball mill; Get the micropowder of 15 grams behind the sterilizations, add in the 100ml ethanol iodine tincture, after stirring gauze is placed in one and soaked 60 minutes, with the gauze oven drying at low temperature, tailor into fritter then, make bandage, promptly get patch.The said preparation external is affixed on the affected part and gets final product during use.
In order to verify the therapeutic effect of Chinese medicine of the present invention, applicant spy has carried out clinical experiment in Guilin City institute of traditional Chinese medicine to it:
Experimental example 1: the treatment shank festers and suppurates
Clean the open sore part of festering with embodiment 2 prepared emulsion formulations, apply embodiment 1 prepared ointment formulation then, grow new meat after three days, wound healing rehabilitation in five days.
Experimental example 2: cure the arm abscess
Clean the skin ulcer face with embodiment 2 prepared emulsion formulations, apply embodiment 1 prepared ointment formulation then, recovery from illness after three days.
Experimental example 3: cure comminuted fracture of pelvis
One middle aged women is because of the traffic accident comminuted fracture of pelvis, cut skin and flesh and clamp big tremulous pulse earlier, after use embodiment 2 prepared emulsion formulations clean a wound, broken bone is connected fixedly sew up wound, apply embodiment 1 prepared ointment formulation at suture, do not occur infection symptoms in the future.
Simultaneously, the applicant has also carried out corresponding zoopery at Chinese medicine of the present invention:
1. liver and the splenomegaly of Canis familiaris L. are partly excised, it is disconnected that the rabbit leg muscle is done crosscut, the big tremulous pulse of ligation at first, and reuse emulsion formulations of the present invention and ointment flap coverage hemorrhagely stop immediately.
2. the lesser gastric curvature and the duodenal antetheca of anesthetized dog are respectively done one in artificial hole, diameter is all about 1 centimetre, pours into powder 9 grams of the present invention, and after 15 seconds, the duodenum perforation is promptly sealed.After treating that animal revives gradually, in the time of can gentle activity, inject 500 milliliters in gruel by stomach tube again, observe two Kong Jiewu medicated porridge liquid and spill.Inject 20 milliliters in 10% sodium chloride by goldbeater's skin internal layer blood vessel again, gastric peristalsis is obviously strengthened, and spills but there is no gruel.Postoperative was cut open the belly and observe the magma thing that intraperitoneal does not have discovery to spill from gastrostome in 8 hours once more, got intraperitoneal body fluid and cultivated negative.
Claims (2)
1. a treatment injures the Chinese medicine of ulcer outward, and it is characterized in that: according to listed as parts by weight, it is made for 0.5～5 part with 1～30 part of chitin, 30～80 parts of OPHICALCITUMs, 10～70 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 0.5～5 part of Herba Agrimoniae and Folium Callicarpae Formosanae.
2. described treatment injures the Chinese medicine of ulcer outward according to claim 1, and it is characterized in that: according to listed as parts by weight, it is made for 0.5 part with 10 parts of chitins, 60 parts of OPHICALCITUMs, 29 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 0.5 part of Herba Agrimoniae and Folium Callicarpae Formosanae.
3. injure the Chinese medicine of ulcer outward according to claim 1 or 2 described treatments, it is characterized in that: described Chinese medicine preparation is powder, ointment, liquid preparation or patch.
4. injure the preparation method of Chinese medicine of ulcer outside the treatment, it is characterized in that: take by weighing chitin 1～30 weight portion, OPHICALCITUM 30～80 weight portions, Pseudobulbus Bletillae (Rhizoma Bletillae) 10～70 weight portions, Herba Agrimoniae 0.5～5 weight portion and Folium Callicarpae Formosanae 0.5～5 weight portion, under 70～90 ℃ of conditions, dried 3～5 hours, be cooled to room temperature, wear into micropowder, sterilization is made various preparation then.
5. described treatment injures the preparation method of Chinese medicine of ulcer outward according to claim 4, it is characterized in that: take by weighing chitin, OPHICALCITUM, Pseudobulbus Bletillae (Rhizoma Bletillae), Herba Agrimoniae and Folium Callicarpae Formosanae, place electric oven, oven dry is 4 hours under 80 ℃ of conditions, taking-up is cooled to room temperature, wear into 10～100 nano level micropowders with pneumatic grinding mill or ball mill, utilize high-pressure ozone storehouse sterilization, make powder then or further make ointment, emulsion formulations or patch.
6. injure the preparation method of Chinese medicine of ulcer outward according to claim 4 or 5 described treatments, it is characterized in that: described ointment is made like this: the micropowder after the sterilization of cancellation poison, steeped 72 hours with the water logging of 5 times of micropowder weight, and fill, promptly.
7. injure the preparation method of Chinese medicine of ulcer outward according to claim 4 or 5 described treatments, it is characterized in that: described emulsion formulations is made like this: the micropowder after the sterilization of cancellation poison, and the water of 20 times of micropowder weight of adding stirs, fill immediately, promptly.
8. injure the preparation method of Chinese medicine of ulcer outward according to claim 4 or 5 described treatments, it is characterized in that: described patch is made like this: get the micropowder of 15 grams behind the sterilizations, add in the 100ml ethanol iodine tincture, after stirring gauze is placed in one and soaked 30～60 minutes, then with the gauze oven drying at low temperature, tailor into fritter, make bandage, promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008103025077A CN101317963B (en) | 2008-07-03 | 2008-07-03 | Traditional Chinese medicine for treating exogenous injury and ulcer and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008103025077A CN101317963B (en) | 2008-07-03 | 2008-07-03 | Traditional Chinese medicine for treating exogenous injury and ulcer and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101317963A CN101317963A (en) | 2008-12-10 |
| CN101317963B true CN101317963B (en) | 2010-12-22 |
Family
ID=40178402
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2008103025077A Expired - Fee Related CN101317963B (en) | 2008-07-03 | 2008-07-03 | Traditional Chinese medicine for treating exogenous injury and ulcer and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101317963B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105148015A (en) * | 2015-09-21 | 2015-12-16 | 广州环亚化妆品科技有限公司 | Traditional Chinese medicine composition with effect of repairing corneous layer and preparation method and application of traditional Chinese medicine composition |
| CN111759889B (en) * | 2020-07-29 | 2023-05-02 | 山东广玉源环保科技有限公司 | Hemostatic composition containing chitin and aerosol thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1208646A (en) * | 1998-09-08 | 1999-02-24 | 郭旸 | Medicine for treating gastrointestinal ulcer and gastritis |
| CN101007125A (en) * | 2007-01-24 | 2007-08-01 | 李怀涛 | Proprietary Chinese medicine for treating ulcerative colitis |
-
2008
- 2008-07-03 CN CN2008103025077A patent/CN101317963B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1208646A (en) * | 1998-09-08 | 1999-02-24 | 郭旸 | Medicine for treating gastrointestinal ulcer and gastritis |
| CN101007125A (en) * | 2007-01-24 | 2007-08-01 | 李怀涛 | Proprietary Chinese medicine for treating ulcerative colitis |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101317963A (en) | 2008-12-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2019517533A (en) | External pharmaceutical composition for treatment of various wound wounds of skin and preparation method thereof | |
| CN103432287A (en) | Tea seed foot bath powder and preparation method thereof | |
| CN101264196B (en) | Externally-applied medicinal composition for treating surgical wound and preparation of ointment thereof | |
| CN101317963B (en) | Traditional Chinese medicine for treating exogenous injury and ulcer and preparation method thereof | |
| CN103566071B (en) | Traditional Chinese medicine composition for treating ulcer and preparation method of powder of traditional Chinese medicine composition | |
| CN102716281B (en) | Care solution for cleaning wounds after operation | |
| CN101002866B (en) | Traditional Chinese medicine for treating animal injuries | |
| CN104474536A (en) | Fresh agrimonia pilosa medicine preparation for treating wounds | |
| CN101708253B (en) | Prickly heat powder | |
| CN106377602A (en) | Dendrobium officinale composite disinfection powder, and preparation method and application method thereof | |
| Davis et al. | History and Evolution of Bandages, Dressings, and Plasters | |
| CN107397886A (en) | Chinese medicine composition for preventing and treating piglet red dysentery and its preparation method and application | |
| CN104189304B (en) | It is a kind of to be used to treat Chinese medicine composition of surgical wound and preparation method thereof | |
| CN106491568A (en) | A kind of marine organisms spray film for treating skin injury and infection and preparation method thereof | |
| CN107595819A (en) | A kind of Nano diamond modified liquid adhesive bandage and preparation method thereof | |
| CN101849992A (en) | Medicament for treating inferior turbinate hypertrophy and method for preparing same | |
| CN1047532C (en) | Anti-headache Chinese proprietary medicine and its preparing method | |
| CN105055713A (en) | Drug composition for preventing or curing bedsore and preparation method thereof | |
| CN101214280B (en) | Chinese medicine for treating burn, scald and sores and preparation thereof | |
| CN105012348A (en) | Bioactive vaginal suppository containing growth factors | |
| CN108355130A (en) | It is a kind of to treat psoriasic temperature sensitive type collagen composite antiphlogistic gel spray and preparation method thereof | |
| Kirschner | CHLOROPHYLL as THERAPY–Cancer–Germs-Intestines | |
| CN1778360A (en) | Burn and scald medicine | |
| CN101306111A (en) | Medicaments for treating animal trauma | |
| CN104739856B (en) | Application of the montmorillonite external pulvis in the drug for preparing treatment skin ulcer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20101222 Termination date: 20110703 |