CN101305981A - Bee-peptide rejuvenating face-cleaning skin-cleaning cream and preparation method thereof - Google Patents
Bee-peptide rejuvenating face-cleaning skin-cleaning cream and preparation method thereof Download PDFInfo
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- CN101305981A CN101305981A CNA2008101232778A CN200810123277A CN101305981A CN 101305981 A CN101305981 A CN 101305981A CN A2008101232778 A CNA2008101232778 A CN A2008101232778A CN 200810123277 A CN200810123277 A CN 200810123277A CN 101305981 A CN101305981 A CN 101305981A
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- clean
- antioxidant
- skin cream
- dried powder
- bee
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- 238000002360 preparation method Methods 0.000 title abstract description 6
- 239000006071 cream Substances 0.000 title abstract 3
- 230000003716 rejuvenation Effects 0.000 title abstract 3
- 238000004140 cleaning Methods 0.000 title 2
- 239000000843 powder Substances 0.000 claims abstract description 19
- 239000003963 antioxidant agent Substances 0.000 claims abstract description 15
- 230000003078 antioxidant effect Effects 0.000 claims abstract description 15
- 150000005846 sugar alcohols Polymers 0.000 claims abstract description 15
- 238000003756 stirring Methods 0.000 claims abstract description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 12
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 claims abstract description 11
- 229920001214 Polysorbate 60 Polymers 0.000 claims abstract description 11
- 235000021355 Stearic acid Nutrition 0.000 claims abstract description 11
- 150000001413 amino acids Chemical class 0.000 claims abstract description 11
- 239000008367 deionised water Substances 0.000 claims abstract description 11
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 11
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims abstract description 11
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims abstract description 11
- 239000008117 stearic acid Substances 0.000 claims abstract description 11
- 239000004094 surface-active agent Substances 0.000 claims abstract description 11
- 238000000034 method Methods 0.000 claims abstract description 10
- 238000004519 manufacturing process Methods 0.000 claims abstract description 8
- 238000002156 mixing Methods 0.000 claims abstract description 8
- 238000010438 heat treatment Methods 0.000 claims abstract description 7
- 244000144987 brood Species 0.000 claims description 17
- 239000002884 skin cream Substances 0.000 claims description 12
- 108010036176 Melitten Proteins 0.000 claims description 11
- VDXZNPDIRNWWCW-JFTDCZMZSA-N melittin Chemical compound NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(N)=O)CC1=CNC2=CC=CC=C12 VDXZNPDIRNWWCW-JFTDCZMZSA-N 0.000 claims description 11
- HVUMOYIDDBPOLL-UHFFFAOYSA-N 2-(3,4-Dihydroxyoxolan-2-yl)-2-hydroxyethyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)C1OCC(O)C1O HVUMOYIDDBPOLL-UHFFFAOYSA-N 0.000 claims description 10
- 230000002421 anti-septic effect Effects 0.000 claims description 10
- 239000000686 essence Substances 0.000 claims description 10
- 239000003921 oil Substances 0.000 claims description 10
- 239000001818 polyoxyethylene sorbitan monostearate Substances 0.000 claims description 10
- 235000010989 polyoxyethylene sorbitan monostearate Nutrition 0.000 claims description 10
- 229940113124 polysorbate 60 Drugs 0.000 claims description 10
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 8
- -1 ethylene glycol glucoside Chemical class 0.000 claims description 7
- 235000006708 antioxidants Nutrition 0.000 claims description 6
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims description 4
- 229930182478 glucoside Natural products 0.000 claims description 4
- 238000009413 insulation Methods 0.000 claims description 3
- 230000003796 beauty Effects 0.000 abstract description 2
- 239000008176 lyophilized powder Substances 0.000 abstract description 2
- HVUMOYIDDBPOLL-XWVZOOPGSA-N Sorbitan monostearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O HVUMOYIDDBPOLL-XWVZOOPGSA-N 0.000 abstract 1
- 239000002480 mineral oil Substances 0.000 abstract 1
- 235000010446 mineral oil Nutrition 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 241000256844 Apis mellifera Species 0.000 description 21
- 239000000047 product Substances 0.000 description 11
- 230000001835 salubrious effect Effects 0.000 description 3
- 108091005804 Peptidases Proteins 0.000 description 2
- 241000241413 Propolis Species 0.000 description 2
- 239000004365 Protease Substances 0.000 description 2
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 239000000706 filtrate Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 229940069949 propolis Drugs 0.000 description 2
- 239000002002 slurry Substances 0.000 description 2
- 239000011550 stock solution Substances 0.000 description 2
- 241000256836 Apis Species 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
- 108010000912 Egg Proteins Proteins 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 241000382353 Pupa Species 0.000 description 1
- 206010048222 Xerosis Diseases 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 230000002301 combined effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 229940056582 human hair preparation Drugs 0.000 description 1
- 230000003301 hydrolyzing effect Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000002808 molecular sieve Substances 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 239000013588 oral product Substances 0.000 description 1
- 210000004681 ovum Anatomy 0.000 description 1
- 238000010422 painting Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
A bee-peptide rejuvenating and cleansing cream and a preparation method thereof relate to a preparation process of a daily beauty product, namely the rejuvenating and cleansing cream. Mixing monoglyceride, Tween 60, span 60 and mineral oil, heating to 70-75 ℃, stirring, keeping the temperature, mixing stearic acid, polyalcohol and amino acid surfactant, heating to 70-75 ℃, mixing and stirring the two components, mixing the bee larva freeze-dried powder, the antioxidant, the preservative, the essence and deionized water when the temperature is reduced to 40-50 ℃, and uniformly stirring to obtain the bee larva lyophilized powder. The method has simple process, is convenient for actual production operation, and due to the adoption of the special process, the product can effectively maintain the characteristics of the bee larva freeze-dried powder, and can well expose the natural color of skin under the combined action of other components, so that the skin is fresh and clear.
Description
Technical field
The present invention relates to a kind of daily cosmetic products---the processing technology of shining clean clean skin cream of face.
Background technology
Honeybee product presented with oral products such as Mel, propolis capsule, Lac regis apis mostly in the past, through scientific experimentation, also contained the effective ingredient that has beauty functions in a large number in the propolis, so a long time ago, people just improve looks with Mel.But because the liquid volume amount is big, the inconvenience transportation, also inconvenience is long-time preserves.There is Crinis Carbonisatus to understand the bee brood freeze-dried powder that little, the convenient transportation of a kind of volume, the long-time effective active components of warp do not change, can prevent the hydrolytic spoilage of active ingredient, be beneficial to long time stored, simultaneously, the general lyophilized powder of the dissolubility of product improves 100%, does not have useless insoluble impurities.
Summary of the invention
The object of the invention is to invent a kind of clean clean skin cream of Melittin refinishing with specific function that being beneficial to of bee brood freeze-dried powder is long time stored, dissolubility is good.
The present invention includes bee brood freeze-dried powder, Dormant oils, monoglyceride, sorbester p18, polysorbate60, stearic acid, antioxidant, polyhydric alcohol, antiseptic, amino acid surfactant, essence and deionized water.
Above-mentioned bee brood freeze-dried powder, Dormant oils, monoglyceride, sorbester p18, polysorbate60, stearic acid, antioxidant, polyhydric alcohol, antiseptic, amino acid surfactant, essence and deionized water account for 3.0%～5.0%, 6.0%, 2.0%, 2.0%, 2.0%, 2.0%, 0.1%, 11.0%, 0.5%, 3.0%, 0.5%, 67.9%～65.9% of gross weight respectively.
The present invention is a kind of application product of bee brood freeze-dried powder, owing to contain bee brood freeze-dried powder in the product, and make the more common cosmetic products of product have the skin of appearing nature true qualities, and make skin salubrious, exquisitely carved clean contour painting energy constantly.
Another object of the present invention is to a kind of manufacture method of invention the said goods.
Earlier respectively with monoglyceride, polysorbate60, sorbester p18 and Dormant oils Hybrid Heating to 70～75 ℃, stir and insulation, with stearic acid, polyhydric alcohol, amino acid surfactant Hybrid Heating to 70～75 ℃, forming a part mixing with above-mentioned two then stirs, when temperature is reduced to 40～50 ℃, bee brood freeze-dried powder, antioxidant, antiseptic, essence and deionized water are sneaked into, stir.
Above-mentioned bee brood freeze-dried powder, Dormant oils, monoglyceride, sorbester p18, polysorbate60, stearic acid, antioxidant, polyhydric alcohol, antiseptic, amino acid surfactant, essence and deionized water account for 3.0%～5.0%, 6.0%, 2.0%, 2.0%, 2.0%, 2.0%, 0.1%, 11.0%, 0.5%, 3.0%, 0.5%, 67.9%～65.9% of gross weight respectively.
This method technology is simple, makes things convenient for the actual production operation, owing to adopted above-mentioned special process, product can effectively keep the bee brood freeze-dried powder self characteristics, also with other composition combined effect under, can appear skin nature true qualities well, make skin constantly salubrious, exquisitely carved clean white.
Antioxidant of the present invention is the 2.6. di-tert-butyl-4-methy phenol.
Described polyhydric alcohol is the ethylene glycol glucoside.
The specific embodiment
One, preparation bee brood freeze-dried powder:
Step:
1, adopts queen bee ovum or the larva or the pupa of the broken roguing of colloid mill, make honeybee slurry;
2, protease and honeybee slurry being mixed, is enzymolysis under 38～55 ℃ the condition in ambient temperature, gets the aqueous solution behind the enzymolysis; Wherein, during mixing, described protease accounts for 0.5～2% of mixture total weight amount;
3, the aqueous solution behind the enzymolysis is filtered through 100 order nylon cloths, get filtrate;
4, with filtrate by the molecular sieve filtration of molecular weight less than 1000D, obtain honeybee stock solution;
5, with honeybee stock solution be-0.09MPa in vacuum, ambient temperature is dry under-30～-40 ℃ the condition, obtains water content and be 0.5～3.0% dried honeybee;
6, dried honeybee being crushed to particle diameter is 80～100 orders, gets bee brood freeze-dried powder.
Two, clean clean skin cream of preparation Melittin refinishing:
1, prescription (percentage by weight):
Bee brood freeze-dried powder 3.0%～5.0% Dormant oils 6.0%
Monoglyceride 2.0% sorbester p18 2.0%
Polysorbate60 2.0% stearic acid 2.0%
Antioxidant 0.1% polyhydric alcohol 11.0%
Antiseptic 0.5% amino acid surfactant 3.0%
Essence 0.5% deionized water 67.9%～65.9%
Above-mentioned antioxidant is 2.6. di-tert-butyl-4-methy phenol (BHT), polyhydric alcohol be the ethylene glycol glucoside.
2, manufacturing process:
Monoglyceride, polysorbate60, sorbester p18, Dormant oils Hybrid Heating are arrived 70-75 ℃, stir and insulation, again stearic acid, polyhydric alcohol, amino acid surfactant Hybrid Heating are arrived 70-75 ℃, forming a part mixing with above-mentioned two stirs, when temperature is reduced to 40-50 ℃, bee brood freeze-dried powder, antioxidant, antiseptic, essence, deionized water are added, stir, be finished product.Finished product is divided in the bottle.
3, usage example:
Certain woman, the age: 39, use this product front face xerosis cutis.
This product on probation 30 days, one day twice, each consumption 2 grams.
After on probation, improve effect: appear skin nature true qualities, skin is constantly salubrious, exquisitely carved clean white.
Claims (8)
1, clean clean skin cream of Melittin refinishing is characterized in that comprising bee brood freeze-dried powder, Dormant oils, monoglyceride, sorbester p18, polysorbate60, stearic acid, antioxidant, polyhydric alcohol, antiseptic, amino acid surfactant, essence and deionized water.
2,, it is characterized in that bee brood freeze-dried powder, Dormant oils, monoglyceride, sorbester p18, polysorbate60, stearic acid, antioxidant, polyhydric alcohol, antiseptic, amino acid surfactant, essence and deionized water account for 3.0%～5.0%, 6.0%, 2.0%, 2.0%, 2.0%, 2.0%, 0.1%, 11.0%, 0.5%, 3.0%, 0.5%, 67.9%～65.9% of gross weight respectively according to clean clean skin cream of the described Melittin refinishing of claim 1.
3, according to claim 1 or clean clean skin cream of 2 described Melittin refinishings, it is characterized in that described antioxidant is the 2.6. di-tert-butyl-4-methy phenol.
4, according to claim 1 or clean clean skin cream of 2 described Melittin refinishings, it is characterized in that described polyhydric alcohol is the ethylene glycol glucoside.
5, the manufacture method of clean clean skin cream of Melittin refinishing according to claim 1, it is characterized in that earlier respectively monoglyceride, polysorbate60, sorbester p18 and Dormant oils Hybrid Heating to 70～75 ℃, stir and insulation, stearic acid, polyhydric alcohol, amino acid surfactant are heated to 70～75 ℃, form a part mixing with above-mentioned two then and stir, when temperature is reduced to 40～50 ℃, bee brood freeze-dried powder, antioxidant, antiseptic, essence and deionized water are sneaked into, stir.
6,, it is characterized in that the bee brood freeze-dried powder, Dormant oils, monoglyceride, sorbester p18, polysorbate60, stearic acid, antioxidant, polyhydric alcohol, antiseptic, amino acid surfactant, essence and the deionized water that add account for 3.0%～5.0%, 6.0%, 2.0%, 2.0%, 2.0%, 2.0%, 0.1%, 11.0%, 0.5%, 3.0%, 0.5%, 67.9%～65.9% of gross weight respectively according to the manufacture method of clean clean skin cream of the described Melittin refinishing of claim 3.
7,, it is characterized in that described antioxidant is the 2.6. di-tert-butyl-4-methy phenol according to the manufacture method of claim 5 or clean clean skin cream of 6 described Melittin refinishings.
8,, it is characterized in that described polyhydric alcohol is the ethylene glycol glucoside according to the manufacture method of claim 5 or clean clean skin cream of 6 described Melittin refinishings.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101232778A CN101305981A (en) | 2008-07-11 | 2008-07-11 | Bee-peptide rejuvenating face-cleaning skin-cleaning cream and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101232778A CN101305981A (en) | 2008-07-11 | 2008-07-11 | Bee-peptide rejuvenating face-cleaning skin-cleaning cream and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101305981A true CN101305981A (en) | 2008-11-19 |
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ID=40122820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2008101232778A Pending CN101305981A (en) | 2008-07-11 | 2008-07-11 | Bee-peptide rejuvenating face-cleaning skin-cleaning cream and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101305981A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2469154A (en) * | 2009-04-02 | 2010-10-06 | Republic Korea | Composition for use in the treatment of wounds and burns comprising bee venom as an active agent |
| AU2013362634B2 (en) * | 2012-12-20 | 2015-05-14 | South China Sea Institute Of Oceanology, Chinese Academy Of Sciences | Bee venom composition with effects of protecting and beautifying lip |
-
2008
- 2008-07-11 CN CNA2008101232778A patent/CN101305981A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2469154A (en) * | 2009-04-02 | 2010-10-06 | Republic Korea | Composition for use in the treatment of wounds and burns comprising bee venom as an active agent |
| AU2013362634B2 (en) * | 2012-12-20 | 2015-05-14 | South China Sea Institute Of Oceanology, Chinese Academy Of Sciences | Bee venom composition with effects of protecting and beautifying lip |
| US10085935B2 (en) | 2012-12-20 | 2018-10-02 | South China Sea Institute Oceanology, Chinese Academy Of Sciences | Bee venom composition with effects of protecting and beautifying lip |
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Legal Events
| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20081119 |