CN101262817B - 用于成像的多次造影剂注射 - Google Patents

用于成像的多次造影剂注射 Download PDF

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Publication number
CN101262817B
CN101262817B CN2006800335475A CN200680033547A CN101262817B CN 101262817 B CN101262817 B CN 101262817B CN 2006800335475 A CN2006800335475 A CN 2006800335475A CN 200680033547 A CN200680033547 A CN 200680033547A CN 101262817 B CN101262817 B CN 101262817B
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China
Prior art keywords
contrast agent
inspection device
measured
relaxation rate
agent application
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Expired - Fee Related
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CN2006800335475A
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English (en)
Chinese (zh)
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CN101262817A (zh
Inventor
H·达恩克
T·舍夫特
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Koninklijke Philips NV
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Koninklijke Philips Electronics NV
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/48—Diagnostic techniques
    • A61B6/481—Diagnostic techniques involving the use of contrast agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • G01R33/56366—Perfusion imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/50—NMR imaging systems based on the determination of relaxation times, e.g. T1 measurement by IR sequences; T2 measurement by multiple-echo sequences

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  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nanotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Signal Processing (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Optics & Photonics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN2006800335475A 2005-09-13 2006-09-07 用于成像的多次造影剂注射 Expired - Fee Related CN101262817B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05108409 2005-09-13
EP05108409.3 2005-09-13
PCT/IB2006/053143 WO2007031910A2 (en) 2005-09-13 2006-09-07 Multiple contrast agent injection for imaging

Publications (2)

Publication Number Publication Date
CN101262817A CN101262817A (zh) 2008-09-10
CN101262817B true CN101262817B (zh) 2011-09-07

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CN2006800335475A Expired - Fee Related CN101262817B (zh) 2005-09-13 2006-09-07 用于成像的多次造影剂注射

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US (2) US8175678B2 (enExample)
EP (1) EP1926425B1 (enExample)
JP (1) JP6059414B2 (enExample)
CN (1) CN101262817B (enExample)
WO (1) WO2007031910A2 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8173819B2 (en) 2005-09-02 2012-05-08 Visen Medical, Inc. Nicotinic and picolinic acid derived near-infrared fluorophores
US8175678B2 (en) 2005-09-13 2012-05-08 Koninklijke Philips Electronics N.V. Multiple contrast agent injection for imaging
CN101951839B (zh) * 2008-01-23 2013-11-06 M·阿韦基乌 利用超声造影剂的呼吸门控治疗评估
EP2247314A4 (en) * 2008-02-01 2013-11-27 Univ Boston CATIONIC CONTRASTING AGENTS AND METHOD FOR THEIR USE
JP5307453B2 (ja) * 2008-05-29 2013-10-02 株式会社日立メディコ 超音波診断装置
JP5360466B2 (ja) * 2008-07-11 2013-12-04 国立大学法人福井大学 Ｐｅｔ薬剤送出装置およびその作動方法
CN104519794B (zh) 2012-08-06 2018-05-22 皇家飞利浦有限公司 基于动态对比增强成像的渗透率度量
DE102015222853A1 (de) * 2015-11-19 2017-05-24 Siemens Healthcare Gmbh Verfahren zum automatischen Ermitteln eines Kontrastmittel-Injektionsprotokolls
WO2017147418A1 (en) 2016-02-24 2017-08-31 Ohio State Innovation Foundation Methods and devices for contrast agent magnetic resonance imaging
EP3382414B1 (de) * 2017-03-28 2024-09-18 Siemens Healthineers AG Verfahren zur durchführung einer angiographischen messung und erstellung einer angiographie
CN111458321B (zh) * 2020-05-22 2021-11-23 南京诺源医疗器械有限公司 一种基于病变部位荧光反馈的诊断系统

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US5545396A (en) * 1994-04-08 1996-08-13 The Research Foundation Of State University Of New York Magnetic resonance imaging using hyperpolarized noble gases
EP0814849A1 (en) * 1995-10-19 1998-01-07 BRACCO International B.V. Magnetically labeled chemoattractants as targeted contrast agents in the nmr imaging of living tissues
US6009342A (en) * 1997-02-28 1999-12-28 The Regents Of The University Of California Imaging method for the grading of tumors
WO2000019227A1 (en) 1998-09-28 2000-04-06 Nycomed Imaging As Method of magnetic resonance imaging
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Also Published As

Publication number Publication date
US20090130023A1 (en) 2009-05-21
EP1926425B1 (en) 2015-08-19
CN101262817A (zh) 2008-09-10
EP1926425A2 (en) 2008-06-04
JP6059414B2 (ja) 2017-01-11
WO2007031910A2 (en) 2007-03-22
JP2009507545A (ja) 2009-02-26
US20120253179A1 (en) 2012-10-04
US8175678B2 (en) 2012-05-08
WO2007031910A3 (en) 2007-10-18
US10154797B2 (en) 2018-12-18

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