CN101249190A - Anti-inflammation sterilizing Chinese medicine compound externally used coating liquid and method of preparing the same - Google Patents
Anti-inflammation sterilizing Chinese medicine compound externally used coating liquid and method of preparing the same Download PDFInfo
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- CN101249190A CN101249190A CNA200810102887XA CN200810102887A CN101249190A CN 101249190 A CN101249190 A CN 101249190A CN A200810102887X A CNA200810102887X A CN A200810102887XA CN 200810102887 A CN200810102887 A CN 200810102887A CN 101249190 A CN101249190 A CN 101249190A
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Abstract
The invention relates to a TCM compound external liniment liquid for antiphlogosis and sterilization and a preparation method, and belongs to the technical field of Chinese medicines. TCM active ingredients that are honeysuckle, scutellaria, safflower, Astragalus roots, rhizoma ligustici wallichii, myrobalam, rhubarb and blood of dragon are mixed and then decocted with water, so that the TCM compound external liniment liquid is made; wherein, the components has the weight as follows: the honeysuckle is 12 to 18g, the scutellaria is 9 to 15g, the safflower is 8 to 15g, the Astragalus roots is 12 to 24g, the rhizoma ligustici wallichii is 8 to 15g, the myrobalam is 12 to 18g, the rhubarb is 12 to 20g, and the blood of dragon is 3 to 6g. The invention has the preparation method for preparing the external liniment liquid that: the medicinal materials are mixed by weight rate, decocted, concentrated and filtered after being stood to cold, and then are added with anionic surfactant that is sodium dodecyl sulfate and broad-spectrum antibacterial preservative that is nipagin esters; the solution is stirred uniformly after dissolution, and then is potted and sterilized, so that the external liniment liquid is made. The TCM compound external liniment liquid is adopted to sterilize and diminish inflammation without allergic reaction, so as to lead the wound to close up rapidly; the TCM compound external liniment liquid is used for skin ulcer and bedsore, and is more particularly applied to the patients suffered from combined multiple skin ulcer of diabetes mellitus.
Description
Technical field
The invention belongs to technical field of Chinese medicines, particularly diabetes merge the Chinese medicine compound externally used coating liquid and the preparation method of multiple cutaneous ulcer treatment.
Background technology
In today that people's living standard improves constantly, because heredity and unsound life style, the sickness rate of diabetes raises year by year, and incident complication-multiple cutaneous ulcer is general especially.
This complication of western medical treatment adopts sterilization and routine to change dressings usually, because the blood glucose level in patients height, ulcer is difficult to healing, and the serious symptom sufferer delay several years does not heal, even has to cut out the trouble limb.Adopt this therapeutic modality, usually will repeatedly change dressings, healing time is long; Make troubles to patient.Also have the Western medicine antibiotic preparation may cause some patient allergy reactions, more increased patient's misery.
Summary of the invention
The objective of the invention is for overcoming the deficiency of existing treatment skin ulcer medicine, a kind of anti-inflammation and sterilization Chinese medicine compound externally used coating liquid and preparation method thereof is proposed, adopt this medicine can carry out bactericidal antiphlogistic simple and conveniently, there is not irritated reaction, make the wound quickly-healing, and preparation is simple, with low cost, is used for skin ulcer, decubital ulcer.Especially be fit to the patient that diabetes merge multiple cutaneous ulcer.
A kind of anti-inflammation and sterilization Chinese medicine compound externally used coating liquid that the present invention proposes, it is characterized in that, form by water is fried after middle pharmaceutically active ingredient Flos Lonicerae, Radix Scutellariae, Flos Carthami, the Radix Astragali, Rhizoma Chuanxiong, Fructus Chebulae, Radix Et Rhizoma Rhei and the Sanguis Draxonis mixing, the weight of each composition is: Flos Lonicerae 12-18 gram Radix Scutellariae 9-15 gram Flos Carthami 8-15 gram Radix Astragali 12-24 restrains Rhizoma Chuanxiong 8-15 and restrains Fructus Chebulae 12-18 gram Radix Et Rhizoma Rhei 12-20 gram Sanguis Draxonis 3-6 gram.
The coating liquid that above-mentioned prescription is made is the 200-300 milliliter.
Above-mentioned coating liquid also can add the gram by anion surfactant dodecylic acid sodium 0.5-1, the adjuvant that broad-spectrum antiseptic antiseptic Buddhist nun Yihe River gold ethyl ester 0.025-0.1 gram is formed.
The method for preparing above-mentioned externally used coating liquid may further comprise the steps:
1) with Flos Lonicerae 12-18 gram Radix Scutellariae 9-15 gram Flos Carthami 8-15 gram Radix Astragali 12-24 gram Rhizoma Chuanxiong 8-15 gram Fructus Chebulae 12-18 gram;
Add after the prescription of Radix Et Rhizoma Rhei 12-20 gram Sanguis Draxonis 3-6 gram mixes with 30-60 amount doubly 25000 milliliters in water-, 50000 milliliters decoct and obtained 20000 milliliters-40000 milliliters of decocting liquids in 1.5-2 hour; Add 20000 milliliters-40000 milliliters once more, decocted 1-1.5 hour, obtain 15000 milliliters-30000 milliliters of secondary decocting liquids;
2) medicinal residues are pressed juicing, and merge with twice decocting liquid, filter once more, and final filtrate is concentrated into 7500 milliliters-15000 milliliters;
3) will concentrate cooling filtrate and add anionic 15-60g and broad-spectrum antiseptic antiseptic ethyl hydroxybenzoate 0.75-6g, dissolving stirs, embedding, and sterilization both must apply liquid, and it is standby to be distributed into 200-300 milliliter bottle.
Above-mentioned preparation method also can be carried out multiple ground to the dose that once drops into according to actual production scale and be enlarged.
The Therapeutic Method of medicine of the present invention: with wound clear up, the 50-100 milliliter soaks the gauze debridement and changes dressings once-a-day.
Characteristics of the present invention and effect:
The present invention is pure Chinese medicinal preparation, and is easy to use, and raw material is easily purchased, without any side effects, and nonirritant does not have allergy, and cheap, the patient is acceptant, can change dressings voluntarily, and is less demanding to aseptic condition.Be used for skin ulcer, decubital ulcer, especially be fit to the patient that diabetes merge multiple cutaneous ulcer.
The specific embodiment
Anti-inflammation and sterilization Chinese medicine compound externally used coating liquid of the present invention and preparation method thereof is described in detail as follows in conjunction with the embodiments:
Embodiment 1: the raw material of Chinese medicine of present embodiment and consumption are: Flos Lonicerae 480 gram, Radix Scutellariae 360 grams, Flos Carthami 240 grams, the Radix Astragali 360 grams, Rhizoma Chuanxiong 240 grams, Fructus Chebulae's 360 grams, Radix Et Rhizoma Rhei 360 grams, Sanguis Draxonis 180 grams (prescription amount 30 times).
Adopt the preparation method of above-mentioned raw materials may further comprise the steps:
1) adds 25000 milliliters in water after the Chinese medicine of above-mentioned each composition is mixed, decocted 2 hours, 20000 milliliters of the inferior decocting liquids of winning; Add 20000 milliliters of the same methods once more and decocted 1.5 hours, decocting liquid is 15000 milliliters for the second time.
2) medicinal residues are pressed juicing, and merge with twice decocting liquid, filter once more, and filtrate is concentrated into 7500 milliliters (it is 1.10 that relative density heat is surveyed);
3) concentrated filtrate is added anionic 18g and broad-spectrum antiseptic antiseptic ethyl hydroxybenzoate 0.75g, dissolving stirs, embedding, and sterilization both must apply 7500 milliliters of liquid, was distributed into 30 bottles.
Embodiment 2: the raw material of Chinese medicine of present embodiment and consumption are: Flos Lonicerae 650 gram, Radix Scutellariae 500 grams, Flos Carthami 500 grams, the Radix Astragali 700 grams, Rhizoma Chuanxiong 500 grams, Fructus Chebulae's 700 grams, Radix Et Rhizoma Rhei 700 grams, Sanguis Draxonis 150 grams (prescription amount 50 times);
Adopt the preparation method of above-mentioned raw materials may further comprise the steps:
1) add 35000 milliliters in water after the Chinese medicine of above-mentioned each composition is mixed, decoct 25000 milliliters of the inferior decocting liquids of winning in 2 hours; Add once more 30000 milliliters of the same methods decocted 1.5 hours 20000 milliliters of decocting liquids for the second time;
2) medicinal residues are pressed juicing, merge with twice decocting liquid, filter once more, and filtrate is concentrated into 12500 milliliters;
3) concentrated filtrate is added anionic 40g and broad-spectrum antiseptic antiseptic ethyl hydroxybenzoate 3g, dissolving stirs, embedding, and sterilization both must apply 12500 milliliters of liquid, was distributed into 50 bottles
The raw material of Chinese medicine and the consumption of embodiment 3 present embodiments are: Flos Lonicerae 840 gram, Radix Scutellariae 840 grams, Flos Carthami 840 grams, the Radix Astragali 1200 grams, Rhizoma Chuanxiong 840 grams, Fructus Chebulae's 960 grams, Radix Et Rhizoma Rhei 1080 grams, Sanguis Draxonis 300 grams (prescription amount 60 times);
Adopt the preparation method of above-mentioned raw materials may further comprise the steps:
1) adds 50000 milliliters in water after the Chinese medicine of above-mentioned each composition is mixed, decocted 2 hours, 40000 milliliters of the inferior decocting liquids of winning; Add once more 35000 milliliters of the same methods decocted 1 hour 30000 milliliters of decocting liquids for the second time;
2) medicinal residues are pressed juicing, merge with twice decocting liquid, filter once more, and filtrate is concentrated into 15000 milliliters;
3) concentrated filtrate is added anionic 54g and broad-spectrum antiseptic antiseptic ethyl hydroxybenzoate 5.4g, dissolving stirs, embedding, and sterilization both must apply 15000 milliliters of liquid, was distributed into 60 bottles
Anti-inflammation and sterilization Chinese medicine compound externally used coating liquid therapeutic effect of the present invention:
This prescription Clinical Practice, year application surplus in the of ten, diabetic foot case 80 examples, controlled observation is cured 48 examples, 30 examples that take a turn for the better, 2 examples that heal, total effective rate 97.5%.
Below illustrate by instantiation:
1 Liu * *, the woman 70 years old, had diabetic history 15 years, coronary heart disease 18 years, left sufficient diabetic gangrene one month, instep and vola integumentary musculature ulcer reach periosteum deeply, connect mutually, with stench, the doctor trained in Western medicine not disease controlling of changing dressings determines left below-Knee amputation, patient's refusal, transfer I chief minister and change dressings with routed more liquid, debridement is once-a-day changed dressings, and the routed more liquid of 250ml every day soaks the gauze external application, suffer from foot slough minimizing gradually, granulation tissue hyperplasia was through treatment in three months, wound heals fully, and skin covers, and is discharged from hospitals upon recovery.
2 king * *, woman, 62 years old, cerebral infarction 12 years, long-term bed, nearly half a year, 8 * 10 * 6 cubic centimetres of skin ulcers appearred in buttocks, burst portion many places, were deep to muscle, changed dressings through using the liquid of healing of bursting, once a day, each 100ml soaks the gauze external application, granulation tissue hyperplasia, healing fully after 50 days.
Claims (5)
1. anti-inflammation and sterilization Chinese medicine compound externally used coating liquid, it is characterized in that, form by water is fried after middle pharmaceutically active ingredient Flos Lonicerae, Radix Scutellariae, Flos Carthami, the Radix Astragali, Rhizoma Chuanxiong, Fructus Chebulae, Radix Et Rhizoma Rhei and the Sanguis Draxonis mixing, the weight of each composition is: Flos Lonicerae 12-18 gram Radix Scutellariae 9-15 gram Flos Carthami 8-15 gram Radix Astragali 12-24 restrains Rhizoma Chuanxiong 8-15 and restrains Fructus Chebulae 12-18 gram Radix Et Rhizoma Rhei 12-20 gram Sanguis Draxonis 3-6 gram.
2. anti-inflammation and sterilization Chinese medicine compound externally used coating liquid according to claim 1 is characterized in that the coating liquid that described prescription is made is the 200-300 milliliter.
3. anti-inflammation and sterilization Chinese medicine compound externally used coating liquid according to claim 1 is characterized in that, described coating liquid also adds the gram by anion surfactant dodecylic acid sodium 0.5-1, the adjuvant that broad-spectrum antiseptic antiseptic Buddhist nun Yihe River gold ethyl ester 0.025-0.1 gram is formed.
4. prepare the method for externally used coating liquid according to claim 1, it is characterized in that, may further comprise the steps:
1) with Flos Lonicerae 12-18 gram Radix Scutellariae 9-15 gram Flos Carthami 8-15 gram Radix Astragali 12-24 gram Rhizoma Chuanxiong 8-15 gram Fructus Chebulae 12-18 gram
Add after the prescription of Radix Et Rhizoma Rhei 12-20 gram Sanguis Draxonis 3-6 gram mixes with 30-60 amount doubly 25000 milliliters in water-, 50000 milliliters decoct and obtained 20000 milliliters-40000 milliliters of decocting liquids in 1.5-2 hour; Add 20000 milliliters-40000 milliliters once more, decocted 1-1.5 hour, obtain 15000 milliliters-30000 milliliters of secondary decocting liquids;
2) medicinal residues are pressed juicing, and merge with twice decocting liquid, filter once more, final filtrate are concentrated into 7500 milliliters-15000 milliliters, cooling;
3) will concentrate cooling filtrate embedding, sterilization both must apply liquid, and it is standby to be distributed into 200-300 milliliter bottle.
5. as method as described in the claim 4, it is characterized in that, in described step 2) in also comprise and add anionic 15-60g and broad-spectrum antiseptic antiseptic ethyl hydroxybenzoate 0.75-6g concentrating cooling filtrate, dissolve and stir.
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| Application Number | Priority Date | Filing Date | Title |
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| CN200810102887XA CN101249190B (en) | 2008-03-28 | 2008-03-28 | Anti-inflammation sterilizing Chinese medicine compound externally used coating liquid and method of preparing the same |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102258803A (en) * | 2011-07-20 | 2011-11-30 | 王旋旋 | Long-acting medical skin sterilization cotton ball |
| CN102631423A (en) * | 2012-05-09 | 2012-08-15 | 白玲强 | Care solution for wound cleaning |
| CN104587519A (en) * | 2014-12-29 | 2015-05-06 | 常州美胜生物材料有限公司 | Dressing containing traditional Chinese medicine |
| CN105560687A (en) * | 2015-06-26 | 2016-05-11 | 吕志强 | Traditional Chinese medicine compound external coating liquid for treating skin ulcers and preparation method and application thereof |
| CN108939130A (en) * | 2017-05-21 | 2018-12-07 | 衢州玛济克医疗科技有限公司 | A kind of bedsore medical dressing and its production method |
| CN111067984A (en) * | 2020-01-15 | 2020-04-28 | 吕志强 | Compound external traditional Chinese medicine coating liquid for treating skin ulcer and preparation method and application thereof |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104815039A (en) * | 2015-04-17 | 2015-08-05 | 吕志强 | Traditional Chinese medicine coating liquid for external use for diminishing inflammation, sterilizing and promoting cell neogenesis and preparation method of coating liquid |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1275611C (en) * | 2004-03-22 | 2006-09-20 | 石许凡 | External remedy 'Jiaochoujing' for treating Hang Kong foot |
| CN100342868C (en) * | 2005-08-19 | 2007-10-17 | 芦虎 | Externally applied medicine for treating dermatosis |
| CN100406051C (en) * | 2006-08-17 | 2008-07-30 | 郑庆华 | External application traditional Chinese medicine for teating acne |
-
2008
- 2008-03-28 CN CN200810102887XA patent/CN101249190B/en not_active Expired - Fee Related
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102258803A (en) * | 2011-07-20 | 2011-11-30 | 王旋旋 | Long-acting medical skin sterilization cotton ball |
| CN102258803B (en) * | 2011-07-20 | 2013-12-04 | 安立 | Long-acting medical skin sterilization cotton ball |
| CN102631423A (en) * | 2012-05-09 | 2012-08-15 | 白玲强 | Care solution for wound cleaning |
| CN102631423B (en) * | 2012-05-09 | 2013-06-19 | 白玲强 | Care solution for wound cleaning |
| CN104587519A (en) * | 2014-12-29 | 2015-05-06 | 常州美胜生物材料有限公司 | Dressing containing traditional Chinese medicine |
| CN105560687A (en) * | 2015-06-26 | 2016-05-11 | 吕志强 | Traditional Chinese medicine compound external coating liquid for treating skin ulcers and preparation method and application thereof |
| CN108939130A (en) * | 2017-05-21 | 2018-12-07 | 衢州玛济克医疗科技有限公司 | A kind of bedsore medical dressing and its production method |
| CN111067984A (en) * | 2020-01-15 | 2020-04-28 | 吕志强 | Compound external traditional Chinese medicine coating liquid for treating skin ulcer and preparation method and application thereof |
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| Publication number | Publication date |
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| CN101249190B (en) | 2010-12-15 |
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