CN101243299A - 基于相移干涉测量术的光纤分析装置 - Google Patents
基于相移干涉测量术的光纤分析装置 Download PDFInfo
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- CN101243299A CN101243299A CNA2006800296131A CN200680029613A CN101243299A CN 101243299 A CN101243299 A CN 101243299A CN A2006800296131 A CNA2006800296131 A CN A2006800296131A CN 200680029613 A CN200680029613 A CN 200680029613A CN 101243299 A CN101243299 A CN 101243299A
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
- G01N21/45—Refractivity; Phase-affecting properties, e.g. optical path length using interferometric methods; using Schlieren methods
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- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
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- Medicinal Chemistry (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
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Abstract
Description
Ab-1 | Ab-2 |
K缔合=1.35×105(M-1S-1) | K缔合=2.01×105(M-1S-1) |
K解离=5.55×10-5(S-1) | K解离=8.15×10-5(S-1) |
KD=K解离/K缔合=3.99×10-9(M) | KD=K解离/K缔合=4.45×10-9(M) |
Claims (35)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US69032405P | 2005-06-13 | 2005-06-13 | |
US60/690,324 | 2005-06-13 | ||
US11/423,671 US7319525B2 (en) | 2003-11-06 | 2006-06-12 | Fiber-optic assay apparatus based on phase-shift interferometry |
US11/423,671 | 2006-06-12 | ||
PCT/US2006/022964 WO2006138294A2 (en) | 2005-06-13 | 2006-06-13 | Fiber-optic assay apparatus based on phase-shift interferometry |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101243299A true CN101243299A (zh) | 2008-08-13 |
CN101243299B CN101243299B (zh) | 2012-01-11 |
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Application Number | Title | Priority Date | Filing Date |
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CN2006800296131A Active CN101243299B (zh) | 2005-06-13 | 2006-06-13 | 基于相移干涉测量术的光纤分析装置 |
Country Status (5)
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US (2) | US7319525B2 (zh) |
EP (1) | EP1891395B1 (zh) |
JP (1) | JP5420897B2 (zh) |
CN (1) | CN101243299B (zh) |
WO (1) | WO2006138294A2 (zh) |
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102656443A (zh) * | 2009-12-18 | 2012-09-05 | 皇家飞利浦电子股份有限公司 | 物质确定设备 |
CN102656443B (zh) * | 2009-12-18 | 2016-01-20 | 皇家飞利浦电子股份有限公司 | 物质确定设备 |
CN104115000A (zh) * | 2012-01-17 | 2014-10-22 | 弗·哈夫曼-拉罗切有限公司 | 用于检测结合亲和力的装置 |
CN104115000B (zh) * | 2012-01-17 | 2016-11-23 | 弗·哈夫曼-拉罗切有限公司 | 用于检测结合亲和力的装置 |
CN110023756A (zh) * | 2016-10-31 | 2019-07-16 | 万迈医疗仪器有限公司 | 基于干涉测量在免疫测定中重复使用测试探针和试剂的方法 |
CN110023756B (zh) * | 2016-10-31 | 2023-06-30 | 万迈医疗仪器有限公司 | 基于干涉测量在免疫测定中重复使用测试探针和试剂的方法 |
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WO2006138294A3 (en) | 2007-07-26 |
US7319525B2 (en) | 2008-01-15 |
WO2006138294A2 (en) | 2006-12-28 |
EP1891395B1 (en) | 2015-09-16 |
JP2008544227A (ja) | 2008-12-04 |
JP5420897B2 (ja) | 2014-02-19 |
CN101243299B (zh) | 2012-01-11 |
EP1891395A2 (en) | 2008-02-27 |
US7656536B2 (en) | 2010-02-02 |
US20070070356A1 (en) | 2007-03-29 |
EP1891395A4 (en) | 2009-03-25 |
US20080144039A1 (en) | 2008-06-19 |
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