CN101228159A - 卡麦角林溶剂化物以及卡麦角林ⅰ型的制备 - Google Patents

卡麦角林溶剂化物以及卡麦角林ⅰ型的制备 Download PDF

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Publication number
CN101228159A
CN101228159A CNA200680027137XA CN200680027137A CN101228159A CN 101228159 A CN101228159 A CN 101228159A CN A200680027137X A CNA200680027137X A CN A200680027137XA CN 200680027137 A CN200680027137 A CN 200680027137A CN 101228159 A CN101228159 A CN 101228159A
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CN
China
Prior art keywords
cabergoline
solvent
structural formula
solvate
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA200680027137XA
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English (en)
Chinese (zh)
Inventor
A·格林伍德
D·麦克哈蒂
P·巴塔拉哈
M·阿罗伊
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Resolution Chemicals Ltd
Original Assignee
Resolution Chemicals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Resolution Chemicals Ltd filed Critical Resolution Chemicals Ltd
Publication of CN101228159A publication Critical patent/CN101228159A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
CNA200680027137XA 2005-07-27 2006-07-27 卡麦角林溶剂化物以及卡麦角林ⅰ型的制备 Pending CN101228159A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0515430.7A GB0515430D0 (en) 2005-07-27 2005-07-27 Preparation of cabergoline
GB0515430.7 2005-07-27

Publications (1)

Publication Number Publication Date
CN101228159A true CN101228159A (zh) 2008-07-23

Family

ID=34976701

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA200680027137XA Pending CN101228159A (zh) 2005-07-27 2006-07-27 卡麦角林溶剂化物以及卡麦角林ⅰ型的制备

Country Status (10)

Country Link
EP (1) EP1912984A1 (no)
JP (1) JP2009502895A (no)
CN (1) CN101228159A (no)
AU (1) AU2006273831A1 (no)
CA (1) CA2616738A1 (no)
GB (1) GB0515430D0 (no)
IL (1) IL188598A0 (no)
NO (1) NO20080461L (no)
WO (1) WO2007012846A1 (no)
ZA (1) ZA200801151B (no)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170095507A1 (en) * 2014-08-17 2017-04-06 Shanxi Zhendong Ante Biopharmaceutical Co., Ltd. Dispersion preparation containing colloidal bismuth pectin and preparing method therefor

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1925616A1 (en) * 2006-10-26 2008-05-28 LEK Pharmaceuticals D.D. Process for the preparation of crystal forms of cabergoline via stable solvates of cabergoline

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0007308D0 (en) * 2000-03-24 2000-05-17 Pharmacia & Upjohn Spa Process for preparing crystalline form | of cabergoline
EP1507777A4 (en) * 2002-03-15 2007-03-07 Pharmacia Corp PROCESS FOR THE PREPARATION OF A CRYSTALLINE FORM I OF CABERGOLIN
AU2003218753A1 (en) * 2002-03-15 2003-09-29 Pharmacia Corporation Process for preparing crystalline form i of cabergoline
CA2525104A1 (en) * 2003-05-08 2004-11-25 Ivax Pharmaceuticals S.R.O. Polymorphs of cabergoline

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170095507A1 (en) * 2014-08-17 2017-04-06 Shanxi Zhendong Ante Biopharmaceutical Co., Ltd. Dispersion preparation containing colloidal bismuth pectin and preparing method therefor

Also Published As

Publication number Publication date
ZA200801151B (en) 2009-04-29
JP2009502895A (ja) 2009-01-29
AU2006273831A1 (en) 2007-02-01
NO20080461L (no) 2008-04-18
CA2616738A1 (en) 2007-02-01
WO2007012846A1 (en) 2007-02-01
EP1912984A1 (en) 2008-04-23
GB0515430D0 (en) 2005-08-31
IL188598A0 (en) 2008-04-13

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WD01 Invention patent application deemed withdrawn after publication

Open date: 20080723