CN101208431A - 用于肿瘤诊断和治疗的组合物和方法 - Google Patents

用于肿瘤诊断和治疗的组合物和方法 Download PDF

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Publication number
CN101208431A
CN101208431A CNA2006800198001A CN200680019800A CN101208431A CN 101208431 A CN101208431 A CN 101208431A CN A2006800198001 A CNA2006800198001 A CN A2006800198001A CN 200680019800 A CN200680019800 A CN 200680019800A CN 101208431 A CN101208431 A CN 101208431A
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CN
China
Prior art keywords
antibody
tat
cell
polypeptide
seq
Prior art date
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Pending
Application number
CNA2006800198001A
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English (en)
Chinese (zh)
Inventor
帕特里克·多德
格雷奇恩·弗朗兹
保罗·波拉基斯
维多利亚·史密斯
苏珊·斯潘塞
吴棣
张泽民
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Genentech Inc
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Genentech Inc
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Filing date
Publication date
Priority claimed from US11/102,501 external-priority patent/US20050272120A1/en
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of CN101208431A publication Critical patent/CN101208431A/zh
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CNA2006800198001A 2005-04-08 2006-04-05 用于肿瘤诊断和治疗的组合物和方法 Pending CN101208431A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/102,501 US20050272120A1 (en) 2001-06-20 2005-04-08 Compositions and methods for the diagnosis and treatment of tumor
US11/102,501 2005-04-08

Publications (1)

Publication Number Publication Date
CN101208431A true CN101208431A (zh) 2008-06-25

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ID=38667206

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2006800198001A Pending CN101208431A (zh) 2005-04-08 2006-04-05 用于肿瘤诊断和治疗的组合物和方法

Country Status (14)

Country Link
EP (1) EP1871886A2 (fr)
JP (1) JP2008535498A (fr)
KR (1) KR20080003405A (fr)
CN (1) CN101208431A (fr)
AU (1) AU2006235436A1 (fr)
BR (1) BRPI0609729A2 (fr)
CA (1) CA2604377A1 (fr)
CR (1) CR9486A (fr)
IL (1) IL185900A0 (fr)
MA (1) MA29587B1 (fr)
MX (1) MX2007012216A (fr)
NO (1) NO20075698L (fr)
RU (1) RU2007141407A (fr)
ZA (1) ZA200707967B (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102741294A (zh) * 2009-11-30 2012-10-17 霍夫曼-拉罗奇有限公司 治疗和诊断表达slc34a2(tat211=seqid2)的肿瘤的抗体
CN104284677A (zh) * 2012-05-14 2015-01-14 霍夫曼-拉罗奇有限公司 用于肿瘤诊断和治疗的组合物和方法
CN113939313A (zh) * 2019-06-06 2022-01-14 电化株式会社 以肽核酸为基础的佐剂
US12016920B2 (en) 2019-06-06 2024-06-25 Denka Company Limited Adjuvant based on peptide nucleic acid

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102741294A (zh) * 2009-11-30 2012-10-17 霍夫曼-拉罗奇有限公司 治疗和诊断表达slc34a2(tat211=seqid2)的肿瘤的抗体
CN103724432A (zh) * 2009-11-30 2014-04-16 霍夫曼-拉罗奇有限公司 治疗和诊断表达slc34a2(tat211=seqid 2)的肿瘤的抗体
CN103755809A (zh) * 2009-11-30 2014-04-30 霍夫曼-拉罗奇有限公司 治疗和诊断表达slc34a2(tat211 = seqid 2)的肿瘤的抗体
CN103755809B (zh) * 2009-11-30 2016-06-01 霍夫曼-拉罗奇有限公司 治疗和诊断表达slc34a2(tat211=seqid2)的肿瘤的抗体
CN103724432B (zh) * 2009-11-30 2016-06-08 霍夫曼-拉罗奇有限公司 治疗和诊断表达slc34a2(tat211=seqid2)的肿瘤的抗体
CN104284677A (zh) * 2012-05-14 2015-01-14 霍夫曼-拉罗奇有限公司 用于肿瘤诊断和治疗的组合物和方法
CN113939313A (zh) * 2019-06-06 2022-01-14 电化株式会社 以肽核酸为基础的佐剂
US12016920B2 (en) 2019-06-06 2024-06-25 Denka Company Limited Adjuvant based on peptide nucleic acid

Also Published As

Publication number Publication date
MA29587B1 (fr) 2008-07-01
IL185900A0 (en) 2008-01-06
AU2006235436A2 (en) 2006-10-19
NO20075698L (no) 2008-01-07
CR9486A (es) 2008-02-20
AU2006235436A1 (en) 2006-10-19
MX2007012216A (es) 2007-12-06
KR20080003405A (ko) 2008-01-07
EP1871886A2 (fr) 2008-01-02
JP2008535498A (ja) 2008-09-04
ZA200707967B (en) 2008-11-26
RU2007141407A (ru) 2009-05-20
BRPI0609729A2 (pt) 2010-04-20
CA2604377A1 (fr) 2006-10-19

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Open date: 20080625