CN101199834A - Chinese medicine compound for treating lung cancer and preparing method thereof - Google Patents
Chinese medicine compound for treating lung cancer and preparing method thereof Download PDFInfo
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- CN101199834A CN101199834A CNA2007103037031A CN200710303703A CN101199834A CN 101199834 A CN101199834 A CN 101199834A CN A2007103037031 A CNA2007103037031 A CN A2007103037031A CN 200710303703 A CN200710303703 A CN 200710303703A CN 101199834 A CN101199834 A CN 101199834A
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Abstract
The invention discloses a compound of the traditional Chinese medicine for treating lung cancer and the preparation method. The invention is mainly prepared by zedoary turmeric, semen lepidii astragalus, radix adenophorae, cortex mori, balloon flower, bitter orange, pinellia tuber, perilla leaf, dry skin of toad, ephedra, ginger and liquorice. The compound of the traditional medicine of the invention has the curative effect of purging the lung and removing phlegm, promoting qi circulation for diuresis and removing lump and resolving hard mass. The invention is mainly for treating lung cancer, mass in the lung, retention of damp and phlegm-heat, deficiency of pulmonary and renal qi and so on. The symptoms includes lung invasion of the drunk fluid, cough and phlegm dyspnea, gradual emaciation, failure to utter a word and lie flat, yellow and greasy fur on the tongue and slippery and rapid pulse. The invention with simple formula, easy production, convenient administration and notable curative effect has wide application value.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, especially a kind of Chinese medicine composition for the treatment of pulmonary carcinoma, and the preparation method of this Chinese medicine composition.
Background technology
Pulmonary carcinoma is common, the multiple malignant tumor of China, and its sickness rate presents ascendant trend year by year in recent years, and its sickness rate ranks first in the big city at present.Cancer be body under various carcinogenic factor effects, the cellular abnormality hypertrophy of local organization and the lump that forms.The traditional Chinese medical science thinks that tumor all shows as qi depression to blood stasis and pyretic toxicity stasis of blood knot mostly, and pulmonary carcinoma then is that positive exogenous pathogen falls into because exopathogenic factor invasion and attack lungs such as wind and cold, summer-heat, wet, dry, fire with the passing of time loose, impairment of dispersing and descending function of the lung, disease coagulate the stagnation of QI, the stasis of blood hinders venation, condenses in bulk and forms.Therefore treat pulmonary carcinoma should adopt activating blood circulation to dissipate blood stasis, promoting the circulation of QI to induce diuresis, promote the production of body fluid moisturize, eliminating the pathogens from the lung eliminating phlegm and eliminating mass eliminate indigestion to be to effect a permanent cure.
At present the treatment lung cancer drugs mainly contains tendril-leaved fritillary bulb cough-relieving sheet, shake bile-fritillary oral liquid, carbetapentane citrate tablet, Ephedrine Tablet and Radix Glycyrrhizae tabellae etc., but its curative effect is not fine, can only mitigate the disease, can not effect a permanent cure, and cure rate is low, easily recurrence, and side effect is big.Therefore the present invention abides by the purpose that Chinese medicine effected a permanent cure, removed virus and cancerous cell, by adopting the method for activating blood circulation to dissipate blood stasis, promoting the circulation of QI to induce diuresis, eliminating the pathogens from the lung eliminating phlegm and eliminating mass eliminate indigestion, the treatment pulmonary carcinoma of low-cost high-efficiency.
Summary of the invention
An object of the present invention is to provide the Chinese medicine composition of the treatment pulmonary carcinoma of a kind of patient's taking convenience, good effect, good stability, no side effects.Another object of the present invention provides a kind of method for preparing described Chinese medicine composition.
Chinese medicine composition of the present invention has the effect of eliminating the pathogens from the lung eliminating phlegm, promoting the circulation of QI to induce diuresis and eliminating mass eliminate indigestion, and mainly curing cancer of lung, lung have long-pending piece, expectorant heat to stop up to contain and insufficiency of QI of the lung and kidney etc., and card is seen lung attacked by retention of fluid, cough phlegm dyspnea, day by day become thin, sound does not go out, it is for sleeping in to put down.Yellow and greasy fur, slippery and rapid pulse.
Technical scheme of the present invention is: a kind of Chinese medicine composition for the treatment of pulmonary carcinoma comprises with the weight portion being the following crude drug of unit: 10～200 parts in 100～600 parts of Rhizoma Curcumae, 100～600 parts of Semen Lepidii (Semen Descurainiae)s, 200～1000 parts of the Radixs Astragali, 100～600 parts of Radix Adenophoraes, 50～500 parts of Cortex Mori, 50～500 parts of Radix Platycodoniss, 50～500 parts of Fructus Aurantiis, 50～500 parts of the Rhizoma Pinelliaes, 50～500 parts of Folium Perillaes, 50～400 parts of dry maxima skins, 50～400 parts in Herba Ephedrae, 10～300 parts in Rhizoma Zingiberis Recens and Radix Glycyrrhizae.
A kind of Chinese medicine composition for the treatment of pulmonary carcinoma is prepared from by following preferred weight part proportion raw material.Preferably, 200～400 parts of Rhizoma Curcumae, 200～400 parts of Semen Lepidii (Semen Descurainiae)s, 300～600 parts of the Radixs Astragali, 200～400 parts of Radix Adenophoraes, 100～300 parts of Cortex Mori, 100～300 parts of Radix Platycodoniss, 100～300 parts of Fructus Aurantiis, 100～300 parts of the Rhizoma Pinelliaes.
Preferably, also comprise 100～300 parts of Folium Perillaes, 100～300 parts of dry maxima skins, 100～300 parts in Herba Ephedrae, 50～200 parts in Rhizoma Zingiberis Recens.
Preferably, also comprise 20～100 parts in Radix Glycyrrhizae.
A kind of optimised quantity for the treatment of each raw material of Chinese medicine composition of pulmonary carcinoma is: 50 parts in 240 parts of Rhizoma Curcumae, 240 parts of Semen Lepidii (Semen Descurainiae)s, 480 parts of the Radixs Astragali, 240 parts of Radix Adenophoraes, 180 parts of Cortex Mori, 180 parts of Radix Platycodoniss, 180 parts of Fructus Aurantiis, 180 parts of the Rhizoma Pinelliaes, 180 parts of Folium Perillaes, 150 parts of dry maxima skins, 150 parts in Herba Ephedrae, 100 parts in Rhizoma Zingiberis Recens and Radix Glycyrrhizae.
A kind of preparation method for the treatment of the Chinese medicine composition of pulmonary carcinoma comprises the following steps:
1, Rhizoma Curcumae, Semen Lepidii (Semen Descurainiae), Radix Adenophorae, Cortex Mori and the dry maxima skin with described weight portion is ground into coarser powder, with 75% alcohol dipping of triplication percolation after 48 hours, leave standstill then, filter, get the extractum 1 of its supernatant concentration to relative density 1.25 (60 ℃ of surveys);
2, the Radix Platycodonis of the residue of step 1 and described weight portion, Fructus Aurantii, the Rhizoma Pinelliae and Radix Glycyrrhizae powder are broken into coarser powder, with 85% alcohol heating reflux twice, and each each 2 hours, to filter, filtrate is concentrated into the extractum 2 of relative density 1.30 (60 ℃ of surveys);
3, the Radix Astragali of the residue of step 2 and described weight portion, Folium Perillae, Herba Ephedrae and Rhizoma Zingiberis Recens are worn into the decocting that adds triplication behind the fine powder and are boiled twice, each each 2 hours, filter, filtrate is concentrated into relative density 1.30 (60 ℃ of surveys) back and merges with extractum 1 and extractum 2, mixing divides the capsule of packing into to get final product after the spray drying.
Preferably, residue and Radix Platycodonis, Fructus Aurantii, the Rhizoma Pinelliae and Radix Glycyrrhizae are dried, pulverized.
Preferably, residue and the Radix Astragali, Folium Perillae, Herba Ephedrae and Rhizoma Zingiberis Recens are decocted with water 2 times.After merging three part extractum, mixing carries out spray drying then.
Preferably, divide the capsule of packing into after the spray drying, make Chinese medicinal capsule.
Prescription of the present invention is made up of 13 flavor Chinese medicines such as Rhizoma Curcumae, Semen Lepidii (Semen Descurainiae), the Radix Astragali, Radix Adenophorae, Cortex Mori, Radix Platycodonis, Fructus Aurantii, the Rhizoma Pinelliae, Folium Perillae, dry maxima skin, Herba Ephedrae, Rhizoma Zingiberis Recens and Radix Glycyrrhizae.Modern pharmacological research shows: in the side is monarch drug with Rhizoma Curcumae, Semen Lepidii (Semen Descurainiae) and the Radix Astragali, and Rhizoma Curcumae can the removing blood stasis circulation of qi promoting, the removing food stagnancy pain relieving, and both kind removing blood stasis, benefaction gas pain relieving again is used for De lumps in the chest and abdomen due to the stagnation of QI and blood, and piece and trusted subordinate's twinge etc. are arranged in the abdomen; The eliminating pathogen from the lung for relieving asthma of Semen Lepidii (Semen Descurainiae) energy, inducing diuresis to remove edema is used for accumulation and obstruction of sputum cough with asthma, breast abdomen hydrops and lung qi and stops up reality etc.; Radix Astragali energy tonifying Qi and lifting yang, inducing diuresis to remove edema, holder skin ulcer granulation promoting; With Radix Adenophorae, Cortex Mori, Radix Platycodonis, Fructus Aurantii and the Rhizoma Pinelliae is ministerial drug, and Radix Adenophorae can nourishing YIN and clearing away lung-heat, and the QI invigorating of eliminating the phlegm has foster lung yin, clearing away lung-heat, lung moistening is dry and the effect of expelling phlegm for arresting cough; Radix Platycodonis can be opened lung qi dispersing gas, and the evacuation of pus of eliminating the phlegm is used for the cough with copious phlegm of inhibited pulmonary QI, the diseases such as lung abscess that freely do not reach pyretic toxicity heap soil or fertilizer over and around the roots lung uncomfortable in chest; The capable expectorant of Fructus Aurantii energy dispelling the stagnated QI, dissolving lump and resolving mass can be controlled the turbid retardance of expectorant, feeling of oppression and fullness in the chest and epigastrium, the stagnation of phlegm thoracic obstruction etc.; Cortex Mori can eliminating pathogen from the lung for relieving asthma, stops lung, cough with dyspnea, failing to lie flat due to dyspnea with the Herba Ephedrae compatibility drink of harnessing the river; Rhizoma Pinelliae energy drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass is used for damp-phlegm, cold-phlegm syndrome; With Folium Perillae, dry maxima skin and Herba Ephedrae is adjuvant drug, Folium Perillae energy relieving the exterior syndrome by diaphoresis, promoting the circulation of QI to alleviate the stagnation in middle-JIAO, cold expelling lung qi dispersing, preventing phlegm from forming and stopping coughing; Dry maxima skin energy subduing swelling and detoxicating, pain relieving and eliminating mass eliminate indigestion; Herba Ephedrae can relieving the exterior syndrome by diaphoresis, and depressed lung-energy dispersing, the kind evil lung qi dispersing that looses be with relieving cough and asthma, can control the cough with asthma of the exterior tightened by pathogenic windcold, sluggishness of lung-QI with the Radix Glycyrrhizae compatibility; Radix Glycyrrhizae and Rhizoma Zingiberis Recens with invigorating the spleen and benefiting QI, coordinating the actions of various ingredients in a prescription are messenger drug, the invigorating middle warmer of Radix Glycyrrhizae energy QI invigorating, and heat-clearing and toxic substances removing, relieving spasm to stop pain, the mediation property of medicine has effects such as spleen reinforcing, lung moistening, detoxifcation, emergency and medicine; Rhizoma Zingiberis Recens energy relieving the exterior syndrome by diaphoresis, warming lung for dispelling cold and preventing phlegm from forming and stopping coughing are used for the treatment of affection of exogenous wind-cold and cough due to wind and cold etc.All medicine compatibilities, play activating blood circulation to dissipate blood stasis, promoting the circulation of QI to induce diuresis altogether, promote the production of body fluid moisturize, the effect of eliminating the pathogens from the lung eliminating phlegm and eliminating mass eliminate indigestion.
Beneficial effect of the present invention is: Chinese medicine composition of the present invention has activating blood circulation to dissipate blood stasis, promoting the circulation of QI to induce diuresis, promote the production of body fluid moisturize, the effect of eliminating the pathogens from the lung eliminating phlegm and eliminating mass eliminate indigestion, be used for the treatment of that pulmonary carcinoma, lung have long-pending piece, expectorant heat to stop up to contain and insufficiency of QI of the lung and kidney etc.; Because Radix Glycyrrhizae has effects such as spleen reinforcing, lung moistening, detoxifcation, emergency and medicine, can be used for the spleen reinforcing lung moistening, the lung moistening so the adding Radix Glycyrrhizae can be eliminated the phlegm better improves curative effect.The present invention fills a prescription simply, produce easy, evident in efficacy, nontoxic, good stability, patient's taking convenience is with a wide range of applications.
The specific embodiment
Embodiment one: Rhizoma Curcumae 100g, Semen Lepidii (Semen Descurainiae) 100g, Radix Astragali 200g, Radix Adenophorae 150g, Cortex Mori 130g, Radix Platycodonis 130g, Fructus Aurantii 120g, Rhizoma Pinelliae 120g, Folium Perillae 120g, dry maxima skin 120g, Herba Ephedrae 100g, Rhizoma Zingiberis Recens 100g and Radix Glycyrrhizae 100g.
Be prepared into capsule by the method for the invention, every capsules 0.5g.
Instructions of taking: every day 3 times, each 5.
Embodiment two: Rhizoma Curcumae 150g, Semen Lepidii (Semen Descurainiae) 150g, Radix Astragali 150g, Radix Adenophorae 150g, Cortex Mori 150g, Radix Platycodonis 150g, Fructus Aurantii 150g, Rhizoma Pinelliae 150g, Folium Perillae 150g, dry maxima skin 150g, Herba Ephedrae 150g, Rhizoma Zingiberis Recens 150g and Radix Glycyrrhizae 150g.
Be prepared into capsule by the method for the invention, every capsules 0.5g.
Instructions of taking: every day 3 times, each 5.
Embodiment three: Rhizoma Curcumae 240g, Semen Lepidii (Semen Descurainiae) 240g, Radix Astragali 480g, Radix Adenophorae 240g, Cortex Mori 180g, Radix Platycodonis 180g, Fructus Aurantii 180g, Rhizoma Pinelliae 180g, Folium Perillae 180g, dry maxima skin 150g, Herba Ephedrae 150g, Rhizoma Zingiberis Recens 100g and Radix Glycyrrhizae 50g.
Be prepared into capsule by the method for the invention, every capsules 0.5g.
Instructions of taking: every day 3 times, each 5.
Chinese medicinal capsule of the present invention can be used for treating pulmonary carcinoma, 125 routine cases is carried out observation of curative effect at present, and wherein 110 routine patients take this medicine 2 all backs effectively, and effective percentage is 88%, therefore is with a wide range of applications.
Claims (4)
1. Chinese medicine composition for the treatment of pulmonary carcinoma is characterized in that the medicine material that raw material contains following weight portion proportioning forms: 10～200 parts in 100～600 parts of Rhizoma Curcumae, 100～600 parts of Semen Lepidii (Semen Descurainiae)s, 200～1000 parts of the Radixs Astragali, 100～600 parts of Radix Adenophoraes, 50～500 parts of Cortex Mori, 50～500 parts of Radix Platycodoniss, 50～500 parts of Fructus Aurantiis, 50～500 parts of the Rhizoma Pinelliaes, 50～500 parts of Folium Perillaes, 50～400 parts of dry maxima skins, 50～400 parts in Herba Ephedrae, 10～300 parts in Rhizoma Zingiberis Recens and Radix Glycyrrhizae.
2. require described Chinese medicine composition according to right 1, it is characterized in that the medicine material that raw material contains following preferred weight part proportioning forms: 20～100 parts in 200～400 parts of Rhizoma Curcumae, 200～400 parts of Semen Lepidii (Semen Descurainiae)s, 300～600 parts of the Radixs Astragali, 200～400 parts of Radix Adenophoraes, 100～300 parts of Cortex Mori, 100～300 parts of Radix Platycodoniss, 100～300 parts of Fructus Aurantiis, 100～300 parts of the Rhizoma Pinelliaes, 100～300 parts of Folium Perillaes, 100～300 parts of dry maxima skins, 100～300 parts in Herba Ephedrae, 50～200 parts in Rhizoma Zingiberis Recens and Radix Glycyrrhizae.
3. require the Chinese medicine composition of described treatment pulmonary carcinoma according to right 1,2, it is characterized in that the optimised quantity of each raw material is: 50 parts in 240 parts of Rhizoma Curcumae, 240 parts of Semen Lepidii (Semen Descurainiae)s, 480 parts of the Radixs Astragali, 240 parts of Radix Adenophoraes, 180 parts of Cortex Mori, 180 parts of Radix Platycodoniss, 180 parts of Fructus Aurantiis, 180 parts of the Rhizoma Pinelliaes, 180 parts of Folium Perillaes, 150 parts of dry maxima skins, 150 parts in Herba Ephedrae, 100 parts in Rhizoma Zingiberis Recens and Radix Glycyrrhizae.
4. require described medicine according to right 3, Rhizoma Curcumae, Semen Lepidii (Semen Descurainiae), Radix Adenophorae, Cortex Mori and the dry maxima skin of described weight portion are ground into coarser powder, with 75% alcohol dipping of triplication percolation after 48 hours, leave standstill then, filter, get the extractum 1 of its supernatant concentration to relative density 1.25 (60 ℃ of surveys); The Radix Platycodonis of residue and described weight portion, Fructus Aurantii, the Rhizoma Pinelliae and Radix Glycyrrhizae powder are broken into coarser powder, with 85% alcohol heating reflux twice, and each each 2 hours, to filter, filtrate is concentrated into the extractum 2 of relative density 1.30 (60 ℃ of surveys); The Radix Astragali of residue and described weight portion, Folium Perillae, Herba Ephedrae and Rhizoma Zingiberis Recens are worn into the decocting that adds triplication behind the fine powder and are boiled twice, each each 2 hours, to filter, filtrate is concentrated into relative density 1.30 (60 ℃ of surveys) back and merges with extractum 1 and extractum 2, mixing divides the capsule of packing into to get final product after the spray drying.Every capsules 0.5g.
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2007103037031A CN101199834A (en) | 2007-12-21 | 2007-12-21 | Chinese medicine compound for treating lung cancer and preparing method thereof |
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| CNA2007103037031A CN101199834A (en) | 2007-12-21 | 2007-12-21 | Chinese medicine compound for treating lung cancer and preparing method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8680053B2 (en) | 2008-07-09 | 2014-03-25 | Quercegen Pharmaceuticals Llc | Improving renal function with quercetin-containing compositions |
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- 2007-12-21 CN CNA2007103037031A patent/CN101199834A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8680053B2 (en) | 2008-07-09 | 2014-03-25 | Quercegen Pharmaceuticals Llc | Improving renal function with quercetin-containing compositions |
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Open date: 20080618 |