CN101199819B - Medicament compound for treating Parkinson syndrome - Google Patents
Medicament compound for treating Parkinson syndrome Download PDFInfo
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- CN101199819B CN101199819B CN2007101142565A CN200710114256A CN101199819B CN 101199819 B CN101199819 B CN 101199819B CN 2007101142565 A CN2007101142565 A CN 2007101142565A CN 200710114256 A CN200710114256 A CN 200710114256A CN 101199819 B CN101199819 B CN 101199819B
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Abstract
The invention discloses a Chinese traditional medicine compound for treating parkinsonism syndrome, belonging to the Chinese traditional medicine field. The Chinese traditional medicine compound for treating parkinsonism syndrome is prepared by ligustrum lucidum of10-20g, red sage root of 5-15g, rhizoma gastrodiae of 5-15g, Cortex Moutan of 5-15g, angelica of 5-15g, earthworm of 10-20g, radix codonopsitis of 10-20g, prepared rhizome of rehmannia of 10-20g, arisaema cum bile of 8-15g, radix curcumae of 10-20g and polygala of 5-15g. Impurities of each crude drug should be removed first, and then the crude drugs are put into an earthen pot. Then 500ml of water is added for decoction for half an hour. The invention is taken with one dosage a day and with one dosage taken twice. The invention is provided with such function as eliminating phlegm and wetness, promoting qi and activating blood circulation. In addition, the invention is extensive in material sources, cheap and easy to get and free of side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of parkinsonism, belong to the field of Chinese medicines.
Background technology
Parkinson disease are a kind of central nervous system degenerative diseases, mainly are because of after the cell generation pathologic change that is arranged in midbrain position " black substance ", the synthetic minimizing of dopamine, and the function that suppresses acetylcholine reduces, and then the excitation of acetylcholine strengthens relatively." Parkinsonism " just appearred in the result that both are unbalance.Parkinsonism is with moving slow, muscle rigidity, static tremor and abnormal posture, and " four main levying are clinical characters.
The medicine negative interaction of western medical treatment parkinsonism is bigger, patient feels seemingly to take a favorable turn when just having Western medicine, the state of an illness is slowly increasing the weight of unconsciously as a result, Western medicine amount and kind are in continuous increase, patient is under the paralysis of kind that continues to increase Western medicine and dose, not only can not finally cure tremor syndromes, also can benumb, anaesthetize patient's nerve.Make each meridians of nerve patient under paralysis, anesthesia of patient day by day block continuous atrophy of each organ pipe and taking off.
Summary of the invention
The objective of the invention is to overcome the deficiency of existing treatment, and a kind of Chinese medicine composition for the treatment of parkinsonism is provided.At the parkinsonism determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, significant curative effect is arranged.
The technical scheme that technical solution problem of the present invention is taked is:
The Chinese medicine composition of this kind treatment parkinsonism, it is characterized in that, the crude drug of making effective ingredient by following weight is: Fructus Ligustri Lucidi 10-20 gram, Radix Salviae Miltiorrhizae 5-15 gram, Rhizoma Gastrodiae 5-15 gram, Cortex Moutan 5-15 gram, Radix Angelicae Sinensis 5-15 gram, Pheretima 10-20 gram, Radix Codonopsis 10-20 gram, Radix Rehmanniae Preparata 10-20 gram, Arisaema Cum Bile 8-15 gram, Radix Curcumae 10-20 gram, Radix Polygalae 5-15 gram.
The further technical scheme of the present invention is: the Chinese medicine composition of this kind treatment parkinsonism, it is characterized in that, make the raw materials of effective components medicine and be: Fructus Ligustri Lucidi 15 grams, Radix Salviae Miltiorrhizae 10 grams by following weight, Rhizoma Gastrodiae 15 grams, Cortex Moutan 10 grams, Radix Angelicae Sinensis 10 grams, Pheretima 10 grams, Radix Codonopsis 10 grams, Radix Rehmanniae Preparata 10 grams, Arisaema Cum Bile 10 grams, Radix Curcumae 15 grams, Radix Polygalae 10 grams.
Preparation and instructions of taking: with the Impurity removal of each crude drug, all medicines of receiving add 500 milliliters in water in marmite earlier, decoct half an hour, and potion on the one is taken at twice.
Pharmacological action:
Fructus Ligustri Lucidi: bitter sweet, flat.Go into liver, kidney channel.Invigorating the liver and kidney, strong waist knee joint.Control interior-heat caused by deficiency of YIN, dizziness, order flower, tinnitus, soreness of the waist and knees, early whitening of beard and hair.Nourishing the liver and kidney, black hair makes eye bright.Be used for vertigo and tinnitus, soreness of the waist and knees, early whitening of beard and hair, poor vision.
Radix Salviae Miltiorrhizae: hardship is slightly cold; GUIXIN, Liver Channel.Activating blood circulation to dissipate blood stasis, the removing heat from blood mind calming.This product is fallen and promoting the circulation of blood, is apt to into blood system, can qualcomm meridian, change stasis, clearing away heart-fire, removing heat from blood heat, and the will of calming the nerves, remove and throb with fear tiredly, be usually used in obstruction of qi in the chest and cardialgia, menstruation portion transfers, skin infection swells and ache, insomnia and congestion disease such as swell and ache.
Rhizoma Gastrodiae: acrid in the mouth, temperature.Go into Liver Channel.Endogenous wind stopping, arresting convulsion.Control dizzy pupil, wind syndrome of head headache, numb limbs and tense tendons, hemiplegia.
Cortex Moutan: heat clearing away, removing heat from blood, and blood, repercussive.Control the pathogenic heat attacking blood system in febrile diseases, send out speckle, infantile convulsion is told, is defeated in battle, is had blood in stool, the hectic fever due to YIN-deficiency consumptive fever, and amenorrhea ， mass in the abdomen, carbuncle and ulcer is pounced on damage.
Radix Angelicae Sinensis: Gan Xin, temperature.Go into the heart, liver, spleen channel.Benefiting blood and regulating blood circulation, menstruction regulating and pain relieving is moisturized laxation.Control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia; Headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; The dryness of the intestine dyschezia is heavy after the bloody dysentery; The carbuncle skin ulcer is stolen, injury from falling down.
Pheretima: heat clearing away, suppressing the hyperactive liver, Zhichuan, collateral dredging.It is manic to control hyperpyrexia, convulsion with spasms, and headache due to pathogenic wind-heat, conjunctival congestion, apoplexy and hemiplegia is panted, sore throat, arthralgia, bleeding from the gum, urinary obstruction, scrofula.
Radix Codonopsis: sweet, flat.Start with, the meridian of Foot-TAI YIN edema caused by disorder of QI.Invigorating the spleen and replenishing QI is promoted the production of body fluid, and nourishes blood.The empty asthenia of body that is used for deficiency of QI in middle-JIAO, weakness of the spleen and stomach, deficiency of both QI and blood is controlled fatigue and lack of strength, and lung qi loses empty.Control lack of appetite, thirsty, chronic diarrhea, proctoptosis.And the two shallow complexions of losing of QI and blood, dizzy cardiopalmus etc.
Radix Rehmanniae Preparata: the both kind YIN nourishing of enriching blood, again can vital essence replenishing and marrow benifiting, cure mainly the cloudy disease of losing oligospermia of all blood deficiency.Major function nourishing the blood and yin, vital essence replenishing and marrow benifiting are used for blood deficiency and yellow complexion, dizzy, cardiopalmus.
Arisaema Cum Bile: clearing away fire and eliminating phlegm, relieving convulsion fixed chronic.Wind-phlegm fan in controlling, the infantile convulsion epilepsy, phlegm-fire is breathed heavily and is coughed, phlegm-accumulating vertigo.
Radix Curcumae: arduous, cold.Go into the heart, lung, Liver Channel.Promoting QI circulation for relieving depression, the removing heat from blood removing blood stasis with potent drugs is controlled all pains of breast abdomen side of body rib, and it is demented to lose the heart, the calentura coma.Spit blood jaundice.
Radix Polygalae: the Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm resolving depression.Control palpitation with fear, forgetful, nocturnal emission, insomnia, cough ant phlegm, the carbuncle skin ulcer is swollen.
Modern medicine is thought: parkinson disease are a kind of central nervous system degenerative diseases, mainly are to change because of the cell generation pathologic that is arranged in midbrain position " black substance ".The traditional Chinese medical science thinks that Parkinsonian etiology and pathogenesis is that the muscle arteries and veins lose to be supported, due to the pathogenic wind stirring inside.Primary disease is more common in middle-aged and elderly people again, or heavy burden impairment caused by overstrain, QI-blood circulation are become estranged, the smooth person of the popular mistake of meridians.Morbidity many because of deficiecny of liver-YIN, not nourishing muscle and tendon of liver, deficiency syndrome mingling with excess syndrome involve gradually or hold concurrently simultaneously and liver spleen kidney all dirty, the state of an illness is heavy by light commentaries on classics, causes QI and blood deficiency eventually, negative and positive are all hindered, so the trunk activity can not be freely, health is shaken, symptoms such as extremity vibration.At the etiology and pathogenesis of primary disease, should be that old man, these characteristics of empty people are had in mind from sending out the patient in the treatment, based on QI and blood regulating, replenishing QI to invigorate the spleen, suppressing the hyperactive liver to relieve the wind syndrome, clearing away fire and eliminating phlegm is held concurrently and is supported brain, dissipating blood stasis collateral dredging with nourishing kidney.We are with the Radix Angelicae Sinensis QI and blood regulating; But Radix Salviae Miltiorrhizae benefiting blood and regulating blood circulation; The Radix Codonopsis replenishing QI to invigorate the spleen; Fructus Ligustri Lucidi, Rhizoma Gastrodiae invigorating the liver and kidney; Fructus Schisandrae Chinensis, Radix Polygalae clearing away fire and eliminating phlegm, relieving convulsion fixed chronic; Pheretima, Cortex Moutan, Radix Curcumae vital essence replenishing and marrow benifiting, promoting QI circulation for relieving depression, removing heat from blood removing blood stasis with potent drugs.All medicine compatibilities are played suppressing the hyperactive liver altogether, are relieved dizziness, high fever, infantile convulsions, epilepsy, etc., eliminating phlegm and removing dampness, the effect of promoting flow of QI and blood.
After the present invention made up said medicine, its drug effect had synergism, had the effect of antiinflammatory softening the hard mass, heat radiation dehumidifying, removing obstruction in the collateral to relieve pain.The Chinese medicine composition of this kind treatment parkinsonism has instant effect aspect the treatment parkinsonism, short treating period, Therapeutic Method is simple, expense is low, without any side effects to health, can advantages such as any adverse effect not arranged to patient's health.
Model case
Example 1: Chen, woman, 66 years old, Cantonese.The symptom of trembling appears in the patient before 3 years, earlier based on upper limb, after develop into lower limb gradually, be diagnosed as parkinson, with the temporary transient controlling symptoms of medicine.Along with the continuous development of the state of an illness, what head did not also stop trembles, and the action effect of medicine worse and worse.Through taking Drug therapy of the present invention after two courses of treatment, the head rolling, hands is trembled phenomenon and is alleviated, and two recoveries from illness courses of treatment continue to take medicine.So far recurrence is not seen in drug withdrawal 2 years.
Example 2: Zhang Hong, woman, people from Anhui, 61 years old.Suddenly sensation headache before 2 years, dizzy, limbs are stiff trembles, and are diagnosed as parkinsonism.Long-term clothes western medicine does not have produce effects.Through taking Drug therapy of the present invention after two courses of treatment, the patient is in high spirits, and arm, somatic tremor shake all slightly alleviate, and are emotionally stable, and treatment wins initial success.Continue to take medicine two courses of treatment, patient recovers well, and limb motion is flexible, the head rolling, and hands is trembled phenomenon and is seldom occurred, and recurrence was not seen in drug withdrawal so far in 1 year.
Example 3, Zhang, man, 68 years old, people from Jinan, Shandong.Patient's morbidity in 2003, head does not independently rock, and general tremor can not be autonomous, is " parkinson " at local hospital diagnosis.Take medicines such as left-handed old madopar, trihexyphenidyl, the state of an illness but progressively increases the weight of, and takes prescription of the present invention and treats a course of treatment, and patient's symptom is alleviated at once, limb tremor, stiff transference cure.Continue to take medicine two courses of treatment, patient recovers well, and limb motion is flexible.Drug withdrawal was had a surplus in 1 year, and symptom is bounce-back not, and life can be got well substantially from more.
The specific embodiment
Embodiment one: the Chinese medicine composition of this kind treatment parkinsonism, it is characterized in that, make the raw materials of effective components medicine and be: Fructus Ligustri Lucidi 15 grams, Radix Salviae Miltiorrhizae 10 grams by following weight, Rhizoma Gastrodiae 15 grams, Cortex Moutan 10 grams, Radix Angelicae Sinensis 10 grams, Pheretima 10 grams, Radix Codonopsis 10 grams, Radix Rehmanniae Preparata 10 grams, Arisaema Cum Bile 10 grams, Radix Curcumae 15 grams, Radix Polygalae 10 grams.
Preparation and instructions of taking: with the Impurity removal of each crude drug, all medicines of receiving add 500 milliliters in water in marmite earlier, decoct half an hour, and potion on the one is taken at twice.
Embodiment two: the Chinese medicine composition of this kind treatment parkinsonism, it is characterized in that, make the raw materials of effective components medicine and be: Fructus Ligustri Lucidi 10 grams, Radix Salviae Miltiorrhizae 10 grams by following weight, Rhizoma Gastrodiae 10 grams, Cortex Moutan 10 grams, Radix Angelicae Sinensis 10 grams, Pheretima 10 grams, Radix Codonopsis 10 grams, Radix Rehmanniae Preparata 15 grams, Arisaema Cum Bile 15 grams, Radix Curcumae 15 grams, Radix Polygalae 10 grams.
Preparation and instructions of taking: with embodiment one.
Embodiment three: the Chinese medicine composition of this kind treatment parkinsonism, it is characterized in that, make the raw materials of effective components medicine and be: Fructus Ligustri Lucidi 15 grams, Radix Salviae Miltiorrhizae 15 grams by following weight, Rhizoma Gastrodiae 15 grams, Cortex Moutan 15 grams, Radix Angelicae Sinensis 10 grams, Pheretima 10 grams, Radix Codonopsis 10 grams, Radix Rehmanniae Preparata 10 grams, Arisaema Cum Bile 10 grams, Radix Curcumae 15 grams, Radix Polygalae 10 grams.
Preparation and instructions of taking: with embodiment one.
Embodiment four: the Chinese medicine composition of this kind treatment parkinsonism, it is characterized in that, make the raw materials of effective components medicine and be: Fructus Ligustri Lucidi 10 grams, Radix Salviae Miltiorrhizae 10 grams by following weight, Rhizoma Gastrodiae 15 grams, Cortex Moutan 15 grams, Radix Angelicae Sinensis 10 grams, Pheretima 10 grams, Radix Codonopsis 10 grams, Radix Rehmanniae Preparata 10 grams, Arisaema Cum Bile 10 grams, Radix Curcumae 15 grams, Radix Polygalae 15 grams.
Preparation and instructions of taking: with embodiment one.
Claims (2)
1. Chinese medicine composition for the treatment of parkinsonism, it is characterized in that, the crude drug of making effective ingredient by following weight is: Fructus Ligustri Lucidi 10-20 gram, Radix Salviae Miltiorrhizae 5-15 gram, Rhizoma Gastrodiae 5-15 gram, Cortex Moutan 5-15 gram, Radix Angelicae Sinensis 5-15 gram, Pheretima 10-20 gram, Radix Codonopsis 10-20 gram, Radix Rehmanniae Preparata 10-20 gram, Arisaema Cum Bile 8-15 gram, Radix Curcumae 10-20 gram, Radix Polygalae 5-15 gram.
2. a kind of Chinese medicine composition for the treatment of parkinsonism according to claim 1, it is characterized in that, make the raw materials of effective components medicine and be: Fructus Ligustri Lucidi 15 grams, Radix Salviae Miltiorrhizae 10 grams by following weight, Rhizoma Gastrodiae 15 grams, Cortex Moutan 10 grams, Radix Angelicae Sinensis 10 grams, Pheretima 10 grams, Radix Codonopsis 10 grams, Radix Rehmanniae Preparata 10 grams, Arisaema Cum Bile 10 grams, Radix Curcumae 15 grams, Radix Polygalae 10 grams.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2007101142565A CN101199819B (en) | 2007-12-19 | 2007-12-19 | Medicament compound for treating Parkinson syndrome |
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| CN2007101142565A CN101199819B (en) | 2007-12-19 | 2007-12-19 | Medicament compound for treating Parkinson syndrome |
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| CN101199819A CN101199819A (en) | 2008-06-18 |
| CN101199819B true CN101199819B (en) | 2010-08-11 |
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Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102600371B (en) * | 2012-03-12 | 2014-01-22 | 上海交通大学医学院附属新华医院 | Traditional Chinese medicine composition for preventing parkinsonism and application of traditional Chinese medicine composition |
| CN104147460A (en) * | 2014-09-02 | 2014-11-19 | 杭州金培科技有限公司 | Traditional Chinese medicinal preparation for treating Parkinson's disease and preparation method thereof |
| CN104547897A (en) * | 2014-12-09 | 2015-04-29 | 张祺 | Traditional Chinese medicine composition for treating parkinson disease |
| CN104800606A (en) * | 2015-04-29 | 2015-07-29 | 赵汝君 | Traditional Chinese medicine composition for treating Parkinson's syndrome |
| CN110279824B (en) * | 2019-05-22 | 2021-07-27 | 曹子成 | Traditional Chinese medicine composition for treating Parkinson's disease and application thereof |
| CN111281927A (en) * | 2020-04-17 | 2020-06-16 | 山西中医药大学 | Traditional Chinese medicine composition for treating Parkinson's disease and preparation method and application thereof |
| CN111407853B (en) * | 2020-06-04 | 2021-07-30 | 孟胜喜 | Traditional Chinese medicine composition for treating Parkinson's disease and preparation method thereof |
| CN115429863B (en) * | 2022-09-01 | 2023-10-13 | 河南大学第一附属医院 | Traditional Chinese medicine composition for treating parkinsonism-related non-motor symptoms |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1840128A (en) * | 2005-04-01 | 2006-10-04 | 包德圻 | Medicine for treating cardiovascular disease |
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| CN1840128A (en) * | 2005-04-01 | 2006-10-04 | 包德圻 | Medicine for treating cardiovascular disease |
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