CN101190120A - Binocular pupil detecting system - Google Patents
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- CN101190120A CN101190120A CNA2006101186249A CN200610118624A CN101190120A CN 101190120 A CN101190120 A CN 101190120A CN A2006101186249 A CNA2006101186249 A CN A2006101186249A CN 200610118624 A CN200610118624 A CN 200610118624A CN 101190120 A CN101190120 A CN 101190120A
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Abstract
The invention discloses a pupil detection system of both eyes, including a pupil detection terminal and a computer which contains a pupil detection software, wherein: the detection terminal includes a camera head and a luminous light source which is arranged at the periphery of the camera head; the detection software in the computer includes: a serial communication module, an image collection module which is connected with the serial communication module, and a processing module which is connected with the image collection module; the invention is characterized in that: the detection terminal is a pupil detection terminal of the both eyes, the pupil detection terminal of the both eyes further includes a front end circuit board which is equipped with the luminous light source, and a main circuit board which is connected with the front end circuit board; the processing module includes a pupil diameter processing submodule, a rest or pupillary light reflex process indicator processing submodule which is connected with the pupil diameter processing submodule and a database submodule which is connected with the pupil diameter processing submodule and the rest or pupillary light reflex process indicator processing submodule. The invention can be widely applied in the field of medical detection and has the advantages of objective, quantitative and accurate detection, support of synchronous detection of pupils of the both eyes and so on.
Description
Technical field
The invention belongs to the medical detecting Instrument technical field, relate in particular to a kind of human body binocular pupil detecting system.
Background technology
Pupillary light reflex is meant that pupil dwindles immediately when with the irradiate light pupil, and light source is removed the rapid restorable physiological phenomenon of back pupil.When stimulating a side pupil with light, this side contracted pupil, remove light after pupil restore again, be called direct light reflex; If separate two (for example using dividing plate, palm) with light tight thing, during with irradiate light one side pupil, the opposite side pupil also can dwindle immediately, is called indirect light reflex.
At present, in medical practice, manual type is adopted in the observation of patient's pupil size, form and light reflex situation more, promptly medical personnel are with pocket lamp irradiation patient's a side pupil, perusal patient's pupil and situation of change thereof.In addition, a kind of survey pupil chi is arranged clinically, can carry out quantitative measurement to the diameter of a side pupil, but its precision only is about 0.5mm.
The weak point of above-mentioned these manual methods is: it is objective, quantitatively, measure accurately that (1) can't carry out the size of pupil and light reflex situation, particularly can't carry out the accurate measurement of time class index, the latter comprises light reflex incubation period, contraction speed etc.; (2) synchronous detecting of pupil of both eyes can not be carried out, thereby the index of pupil indirect light reflex and light reflex nerve conduction path can't be drawn; (3) all belong to the subjective experience judgement, different medical personnel's check result may differ greatly, and is repeatable poor; (4) can't obtain objectively to write down to preserve, can not hold a consultation afterwards, make troubles to clinical and research work as medical evidence.
Domestic applications belong to the neurobiology checkout gear number for the invention of 200410079526.X has proposed a kind of drug addict's pupillary movements method for quick and device thereof.This invention reaches video signal collecting card on the computer with the view data of pupil in the mode of video signal, becomes digital signal by the video analog digital conversion and makes further Flame Image Process; Compare with the data base, finally tested whether the drug abuse made differentiation.This device is made up of glasses and computer; Wherein, the eye-shade of plastics is housed on the glasses, is fixed on an infrared miniature close-shot photographic head on the eye-shade of plastics, the infrared light sources that its both sides LED constitutes, and 3 red light emitting diodes that are positioned at shade the right; Data acquisition and processing (DAP) software is housed in the computer.
The weak point of foregoing invention is: 1) can only carry out simple eye pupil and detect, can not carry out the detection of pupil of both eyes simultaneously, thereby can not obtain the index of pupil indirect light reflex and light reflex nerve conduction path; 2) adopt the analog video shooting, need convert digital picture to by the video signal collecting card on the computer, rather than direct capturing digital image; 3) do not provide the specific targets of pupil, but, judge tested whether the drug abuse by making comparisons with the data base; 4) object distance of its photographic head is non-adjustable, and light intensity, the time limit of stimulation are non-adjustable; 5) belong to the drug rehabilitation field, rather than the medical detecting Instrument field.
Summary of the invention
Technical problem to be solved by this invention provides a kind of binocular pupil detecting system, and it can be objective, quantitatively, exactly the diameter of pupil is measured, and then can carry out quantitative measurement and record to the tranquillization process and the light reflex process of pupil.The technical scheme that it adopts is: a kind of binocular pupil detecting system, comprise pupil sense terminals and the computer that pupil detects software that contains that is connected with terminal, and wherein: sense terminals comprises photographic head, is positioned at the illuminating source of photographic head periphery; Detection software in the computer comprises: the serial communication module, the image capture module that is connected with the serial communication module, and the processing module that is connected with image capture module, it is characterized in that: sense terminals is the pupil of both eyes sense terminals, this pupil of both eyes sense terminals also comprises the front-end circuit plate that illuminating source is installed, and the main circuit board that is connected with the front-end circuit plate; Data base's submodule that described processing module comprises pupil diameter processing sub, the tranquillization that is connected with the pupil diameter processing sub or light reflex in-process metrics processing sub, is connected with tranquillization or light reflex in-process metrics processing sub with the pupil diameter processing sub.Wherein, the serial communication module has realized the self-defining serial port communicating protocol of a cover.
The used photographic head of the present invention is two infrared close-shot photographic head of numeral; The illuminating source that the pupil of both eyes sense terminals is adopted is the LED that sends out infrared light and visible light that is installed on the front-end circuit plate; Pupil diameter processing sub of the present invention comprise image gray-scale level change little submodule, the little submodule of rim detection that is connected with image gray-scale level conversion boy module, the little submodule of noise reduction that is connected with rim detection boy module, be connected with noise reduction boy module do the little submodule of match circle, with do match and justify image effectiveness that boy's module is connected and judge little submodule and judge that with the image effectiveness effective image pupil diameter that boy's module is connected calculates little submodule.
The invention has the beneficial effects as follows: owing to adopt digital image acquisition and computer software to handle, the detection data of gained pupil index are more accurate, objective; And, but because eyes synchronous acquisition image, can obtain to comprise the pupil tranquillization process of nerve conduction index of indirect light reflex and light reflex path and many-sided index of light reflex process; Also can keep the foundation of patient's inspection record by database technology as the medical evidence or the consultation of doctors.
Description of drawings
Accompanying drawing 1 is a structural representation of the present invention;
Accompanying drawing 2 is pupil sense terminals main circuit board structural representations;
Accompanying drawing 3 is object distance adjusting device structural representations;
Accompanying drawing 4 is pupil diameter processing sub structural representations.
The specific embodiment mode
The invention will be further described below in conjunction with accompanying drawing:
As shown in Figure 1, the present invention includes pupil of both eyes sense terminals 1 and the computer 2 that pupil detects software that contains that is connected with terminal, wherein: sense terminals comprises two photographic head 101, is positioned at the illuminating source 102 of photographic head periphery, detection software in the computer comprises: the serial communication module, the image capture module that is connected with the serial communication module, and the processing module that is connected with image capture module; This pupil of both eyes sense terminals also comprises the front-end circuit plate 103 that illuminating source 102 is installed, and the main circuit board 104 that is connected with front-end circuit plate 103; Data base's submodule 20203 that described processing module 202 comprises pupil diameter processing sub 20201, the tranquillization that is connected with pupil diameter processing sub 20201 or light reflex in-process metrics processing sub 20202, is connected with tranquillization or light reflex in-process metrics processing sub 20202 with pupil diameter processing sub 20201.
For the effectively collection of control figure picture, between pupil sense terminals 1 and image capture module 201, be connected with an image acquisition control module, by computer 2 and special-purpose connection cable 4 control instruction is sent to pupil sense terminals 1, the acquisition parameter of control photographic head 101 comprises time of exposure, color etc.The picture frame form that image capture module 201 collects is a 24bit RGB bitmap, and image sequence is passed to pupil diameter processing sub 20201.
The image that collects in order to preserve, be convenient to later playback and analysis again, can be connected with a video file module with image capture module 201 and pupil diameter processing sub 20201, after the image sequence of having gathered a tranquillization or light reflex process, all image sequences are saved in the video file module as video flowing, can pass to pupil diameter processing sub 20201 to these image sequences and reanalyse processing by reading video file when needed.
Pupil sense terminals 1 adopts special-purpose connection cable 4 to be connected with computer 2 among Fig. 1.Two are detected photographic head 101 and are respectively applied for the binocular images of gathering the detected person simultaneously, by the USB cable in the special-purpose connection cable 4 of pupil sense terminals view data is sent to computer 2, computer 2 at the realtime image data that receives by the Digital Image Processing algorithm, draw various detection indexs, and the mode with numerical value and figure shows on the display device of computer 2.Detect photographic head 101 and adopt the digital camera of supporting the microspur infrared photography, can clearly obtain eye image.
The front-end circuit plate 103 of one embodiment of the invention is equipped with 2 visible light LED and 2 infrared LEDs.Perforate is left at the middle part of front-end circuit plate 103, and the camera lens part that allows to detect photographic head 101 is therefrom passed through.Each LED be evenly distributed in detect photographic head 101 camera lenses around, make the eyeball image irradiation of collection even, imaging is clear.The opening and closing of visible light LED and infrared LED utilize the timer internal of microcontroller (MCU) 10404, and the control signal by LED control module 10401 decides.Except that the opening and closing (being the luminous time limit) of control visible light LED and infrared LED, microcontroller (MCU) 10404 also adopts PWM (pulse width modulation) mode accurately to control its luminosity by LED control module 10401.
For the eye that makes those who are investigated is in best measured position, two photographic head of pupil of both eyes sense terminals can be connected with an object distance adjusting device respectively, as shown in Figure 3, this object distance adjusting device comprises motor 501, the differential gear housing 502 that is connected successively with motor, screw mandrel 503, the photographic head carriage 504 that is connected with screw mandrel 503, and the guide rail 505 and the forward and backward switch 506,507 that touches that places on the guide rail that are used to put carriage.
The structure of the main circuit board 104 that is connected with the object distance adjusting device comprises LED control module 10401, motor drive module 10402, serial communication module 10403 and microcontroller (MCU) 10404 as shown in Figure 2.It also is to be connected with computer 2 by special-purpose connection cable 4.Computer 2 is sent to serial communication module 10403 with control instruction, 10403 pairs of data of receiving of serial communication module are carried out level conversion, the ECL level signal that universal serial bus is used converts the Transistor-Transistor Logic level signal that microcontroller (MCU) 10404 can be accepted to, and sends to microcontroller (MCU) 10404.Microcontroller (MCU) 10404 is analyzed, is handled the instruction that receives according to self-defined communications protocol, and controls corresponding LED control module 10401 respectively or/and the action of motor drive module 10402 according to concrete command content.After motor drive module 10402 in the main circuit board 104 receives the motor rotation control instruction that microcontroller (MCU) 10404 sends, drive motors 501 direction and speed is according to the rules rotated, and the output shaft of process differential gear housing 502 acts on screw mandrel 503, by screw mandrel 503 rotation of motor 501 is become and to detect seesawing of photographic head carriage 504, guide rail 505 has played the effect of constraint detection photographic head carriage 504 movement locus, and guide rail 505 is fixed on the order tube of terminal.The front-end and back-end of guide rail 505 are equipped with respectively and are touched switch 506 and 507, when detection photographic head carriage 504 moves to front/rear maximum position, it is closed to touch switch 506/507 contact, send one and feed back signal to microcontroller (MCU) 10404, microcontroller (MCU) 10404 will send the rotation that instruction stops object distance adjustment motor 501 after receiving this signal, avoids motor overload.Detect photographic head 101 and be fixed on the front end that detects photographic head carriage 504, because detection photographic head carriage 504 carries detection photographic head 101 and seesaws, with respect to those who are investigated's eyeball reducing and increasing of object distance, therefore can avoid because of detecting photographic head 101 fixed focal length, and the unsharp problem of detection photographic head 101 imagings that the not equal factor in those who are investigated's eyeball curvature and position causes, guarantee favorable imaging quality, improved the detection accuracy of every index.
Fig. 4 is the structure chart of pupil diameter processing sub 20201, it comprise image gray-scale level conversion boy module 301, the rim detection boy's module 302 that is connected with image gray-scale level conversion boy module, the noise reduction boy module 303 that is connected with rim detection boy module, be connected with noise reduction boy module do the round boy's module 304 of match, with make image effectiveness judgement boy module 305 that the round boy's module of match is connected and the effective image pupil diameter calculating boy module 306 that is connected with image effectiveness judgement boy module.
Change the gray scale image that 301,24 RGB images of boy's module are converted into 8 by image gray-scale level, conversion method is: GTG value=R * 0.3+G * 0.59+B * 0.11.
302 pairs of gray scale images of rim detection boy's module use the Sobel edge detection operator to carry out rim detection.Use two Sobel edge detection operators, one is used for the detection level edge, and another is used for the detection of vertical edge, and they are as follows respectively:
-1 -2 -1 ′-1 0 1′
0 0 0 -2 0 2
1 2 1 -1 2 1
The Sobel horizontal edge detects operator Sobel vertical edge and detects operator
All use above-mentioned two operators to make two-dimensional convolution to each point in the image, obtain one by 0,1 two-dimensional matrix of forming, the edge image after the binaryzation that Here it is.Value is that 1 point is illustrated on the edge, and value is that 0 point is represented not on the edge.Comprise in this edge image that pupil contour edge, eyelash edge, eyebrow edge and LED are radiated at formed bright spot edge such as reflective on cornea, the retina etc.
Noise reduction boy module 303 is used square frame translation in edge image of a n * n, if does not intersect with any edge on four limits of this square frame, then the value of being had a few in the square frame is changed to 0, has so just removed the noise of scope less than n * n.In order the pupil contour edge not to be removed by mistake, must guarantee that the value of n is less than the pupil diameter of expecting in this image (unit is a pixel value).For the pupil diameter that obtains expecting, can be with reference to the pupil diameter information of former frame image.
Make match circle boy module 304 and use Hough conversion match circle in edge image.In the effective edge image of a frame, the most approaching circle of pupil contour edge in general uses the Hough algorithm can calculate circle in the edge image.Using Hough algorithm computation bowlder, specifying the minima and the maximum of circular diameter, these two values have determined the diameter of a circle scope that finds out.Similarly, can decide these two values with reference to the pupil diameter of former frame image.Simulate central coordinate of circle and diameter after the Hough conversion.
The image effectiveness judges that boy's module 305 judges according to the feature of normal pupil image whether the circle that back obtains meets the pupil profile.The diameter of a circle of supposing match in previous step is D (unit is a pixel value), the center of circle be C (x, y).If any establishment in the following condition, then this image is invalid:
In the image that noise reduction boy module 303 obtains, with do circle that match circle boy module 304 obtains around get a concentric annulus.Add up the number of the intra-annular edge pixel point of this circle, if the number of these points less than certain empirical value, this two field picture is invalid.Can get rid of the circle that scattered marginal point institute match is come out like this.
In this annulus, orient four points, correspond respectively to the point of transverse axis coordinate figure maximum, the point of transverse axis coordinate figure minimum, the point of ordinate of orthogonal axes value maximum and the point of ordinate of orthogonal axes value minimum, if four points of this that find out are not four different points, this two field picture is invalid.Can get rid of the circle that comes out by less than the circular arc institute match of 90 degree like this, the image that part is closed one's eyes just has this feature.
All pixels in the scanning gray scale image in this circle count the number of GTG value less than the pixel of certain empirical value, if this number less than 1/3 (empirical value) of area of this circle, this two field picture is invalid.Effectively the color of most of pixel of pupil region should be (LED is radiated at except the reflective formed bright spot on the retina) of inclined to one side black in the pupil image.Can get rid of blink image and acorea image like this.
The actual value (mm) that effective image pupil diameter calculating boy module 306 calculates pupil diameter is: other pixel of D * this eye is apart from (mm).Pixel is apart from being meant the actual range apart from representative between adjacent two pixels in this image.
Data base's submodule 20203 is saved in the data base to the pupil index of this two field picture.
At the tranquillization process, the workflow of tranquillization or light reflex in-process metrics processing sub 20202 is as follows:
1) obtain the pupil index of the tranquillization procedural image sequence that pupil diameter processing sub 20201 calculates, the image sequence of an eye is one road image;
2) adding up the number of image frames of this time process efficiency index, if the number of image frames of efficiency index, judges then that this time process is invalid less than the certain percentage of all images frame number, otherwise is effective;
3), calculate following tranquillization in-process metrics with statistical method to effective procedure: as meansigma methods, maximum, minima, fluctuating margin, standard deviation, standard error, confidence interval etc.
Data base's submodule 20203 is saved in the data base to this tranquillization in-process metrics.
At the light reflex process, the workflow of tranquillization or light reflex in-process metrics processing sub 20202 is as follows:
1) obtains the pupil index of the light reflex image sequence that pupil diameter processing sub 20201 calculates, the most for a long time, have left eye directly (the stimulation left eye is measured left eye), left eye indirect (the stimulation right eye is measured left eye), right eye direct (stimulating right eye measurement right eye), right eye indirect (stimulating left eye measurement right eye) 4 road images.
2) adding up the number of image frames of this time process efficiency index, if the number of image frames of efficiency index, judges then that this time process is invalid less than the certain percentage of all images frame number, otherwise is effective.
3), calculate following light reflex index according to following method to effective light reflex process:
Incubation period: after the photostimulation, the absolute value of the difference of pupil diameter and pupil tranquillization diameter is greater than the acquisition time and the difference of photostimulation time started of first two field picture (this two field picture is called picture frame incubation period) of collapse threshold incubation period;
Contraction time: the acquisition time of a two field picture of pupil diameter value minimum and incubation period picture frame the difference of acquisition time;
Tranquillization diameter: the meansigma methods of the pupil diameter of effective image of gathering before the photostimulation;
Shrinkage peak diameter: the diameter (corresponding this two field picture be called peak image frame) of pupil contraction during to minima;
Shrinkage amplitude :=tranquillization diameter-shrinkage peak diameter;
Shrinkage ratio :=shrinkage amplitude/tranquillization diameter;
Maximal velocity of contraction: the sliding window that uses fixed length, since incubation period picture frame between the sampled point the peak image frame, slide, only handle effective image, use linear regression fit to go out linear equation to the sampled data in the sliding window, collinear slope is exactly the contraction speed of sampled point correspondence in the sliding window, mobile one by one sliding window obtains next contraction speed value to next sampled point, and the absolute value maximum is exactly maximal velocity of contraction in the contraction speed of all sliding windows;
Initial diastolic velocity: from the peak image frame, use the pupil diameter of the effective image of consecutive numbers frame of fixed length to go out linear equation with linear regression fit, this collinear slope is exactly initial diastolic velocity;
Diastasis diameter: before the next photostimulation or the pupil diameter in sampling latter stage;
The diastole amplitude :=diastasis diameter-shrinkage peak diameter;
Be retracted to time of 50%, be retracted to time of 75%, time of the time of diastole to 50%, diastole to 75%, average shrinkage speed etc.
4) be not effective light reflex process of eyes at the configuration eye, the light reflex in-process metrics calculates the nerve conduction index that little submodule also can calculate this time light reflex process, uses following method to calculate following index:
Left eye path introduction time: incubation period=left eye direct light reflex incubation period-left eye indirect light reflex;
Right eye path introduction time: incubation period=right eye direct light reflex incubation period-right eye indirect light reflex;
Eyes on average import into incubation period :=(left eye path introduction time+right eye path introduction time)/2;
The left eye path spreads out of the time: incubation period=left eye direct light reflex incubation period-right eye indirect light reflex;
The right eye path spreads out of the time: incubation period=right eye direct light reflex incubation period-left eye indirect light reflex;
Eyes on average spread out of incubation period :=(left eye path spread out of time+the right eye path spreads out of the time)/2.
Data base's submodule 20203 is saved in the data base to this light reflex in-process metrics.
Parameter is set separately when system's support is checked at every turn, comprises tranquillization process and light reflex process, and keep these parameters in the data base.System also has photographic head management, terminal unit management, those who are investigated's management, inspection record management, show pupil diameter curve, printed report, analyze, measure calibration, manual measurement again, function such as import and export.
Claims (9)
1. a binocular pupil detecting system comprises pupil sense terminals and the computer that pupil detects software that contains that is connected with terminal, and wherein: sense terminals comprises photographic head, is positioned at the illuminating source of photographic head periphery; Detection software in the computer comprises: the serial communication module, the image capture module that is connected with the serial communication module, and the processing module that is connected with image capture module, it is characterized in that: sense terminals is the pupil of both eyes sense terminals, this pupil of both eyes sense terminals also comprises the front-end circuit plate that illuminating source is installed, and the main circuit board that is connected with the front-end circuit plate; Data base's submodule that described processing module comprises pupil diameter processing sub, the tranquillization that is connected with the pupil diameter processing sub or light reflex in-process metrics processing sub, is connected with tranquillization or light reflex in-process metrics processing sub with the pupil diameter processing sub.
2. binocular pupil detecting system as claimed in claim 1 is characterized in that the detection software in the computer also comprises the image acquisition control module that is connected between pupil sense terminals and the image capture module.
3. binocular pupil detecting system as claimed in claim 1 is characterized in that the detection software in the computer also comprises the video file module that is connected with the pupil diameter processing sub with image capture module.
4. binocular pupil detecting system as claimed in claim 1 is characterized in that the photographic head that the pupil of both eyes sense terminals is adopted is two infrared close-shot photographic head of numeral.
5. binocular pupil detecting system as claimed in claim 1 is characterized in that the illuminating source that the pupil of both eyes sense terminals is adopted is the semiconductor diode of sending out infrared light and visible light that is installed on the front-end circuit plate.
6. binocular pupil detecting system as claimed in claim 1 is characterized in that two photographic head of pupil of both eyes sense terminals are connected with the object distance adjusting device respectively.
7. binocular pupil detecting system as claimed in claim 6, it is characterized in that described object distance adjusting device comprises motor, the differential gear housing that is connected successively with motor, screw mandrel, the photographic head carriage that is connected with screw mandrel, and the guide rail and the forward and backward switch that touches that places on the guide rail that are used to put carriage.
8. binocular pupil detecting system as claimed in claim 1 is characterized in that the main circuit board of described pupil of both eyes sense terminals comprises LED control module, motor drive module, serial communication module and microcontroller.
9. as the described binocular pupil detecting system of above-mentioned arbitrary claim, it is characterized in that described pupil diameter processing sub comprise image gray-scale level change little submodule, the little submodule of rim detection that is connected with image gray-scale level conversion boy module, the little submodule of noise reduction that is connected with rim detection boy module, be connected with noise reduction boy module do the round little submodule of match, with make the image effectiveness that the round boy's module of match is connected and judge that little submodule calculates little submodule with the effective image pupil diameter that is connected with image effectiveness judgement boy module.
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| CN102961119A (en) * | 2012-11-26 | 2013-03-13 | 黄立贤 | Centrometer |
| CN103445759A (en) * | 2013-09-06 | 2013-12-18 | 重庆大学 | Self-operated measuring unit for reaction of pupil aperture to light based on digital image processing |
| CN104068827A (en) * | 2014-06-25 | 2014-10-01 | 深圳市斯尔顿科技有限公司 | Self-service eye comprehensive detection method and detection equipment |
| CN104739367A (en) * | 2015-03-14 | 2015-07-01 | 中国科学院苏州生物医学工程技术研究所 | Binocular pupil light synthetic detection system |
| CN104739366A (en) * | 2015-03-14 | 2015-07-01 | 中国科学院苏州生物医学工程技术研究所 | Portable binocular pupil detection device |
| CN104739364A (en) * | 2015-03-14 | 2015-07-01 | 中国科学院苏州生物医学工程技术研究所 | Binocular pupil light reflex tracking system |
| CN105433899A (en) * | 2015-11-30 | 2016-03-30 | 中国科学院苏州生物医学工程技术研究所 | Pupil detection device |
| CN105520713A (en) * | 2015-11-30 | 2016-04-27 | 中国科学院苏州生物医学工程技术研究所 | Binocular pupil light reflex measuring equipment |
| CN107358224A (en) * | 2017-08-18 | 2017-11-17 | 北京工业大学 | A kind of method that iris outline detects in cataract operation |
| CN110251074A (en) * | 2019-06-19 | 2019-09-20 | 重庆市中医院 | Multifunctional medical detection system |
| CN111772575A (en) * | 2020-06-02 | 2020-10-16 | 岭南师范学院 | LED (light emitting diode) -based optical nondestructive special children detector and detection method |
| CN113405505A (en) * | 2020-03-16 | 2021-09-17 | 同方威视技术股份有限公司 | Method and device for determining distance and height based on multiple sensors |
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| CN102961119B (en) * | 2012-11-26 | 2015-01-07 | 深圳恒兴视光科技有限公司 | Centrometer |
| CN102961119A (en) * | 2012-11-26 | 2013-03-13 | 黄立贤 | Centrometer |
| CN103445759A (en) * | 2013-09-06 | 2013-12-18 | 重庆大学 | Self-operated measuring unit for reaction of pupil aperture to light based on digital image processing |
| CN104068827A (en) * | 2014-06-25 | 2014-10-01 | 深圳市斯尔顿科技有限公司 | Self-service eye comprehensive detection method and detection equipment |
| CN104739366B (en) * | 2015-03-14 | 2016-08-24 | 中国科学院苏州生物医学工程技术研究所 | A kind of portable binocular pupil detector |
| CN104739367A (en) * | 2015-03-14 | 2015-07-01 | 中国科学院苏州生物医学工程技术研究所 | Binocular pupil light synthetic detection system |
| CN104739366A (en) * | 2015-03-14 | 2015-07-01 | 中国科学院苏州生物医学工程技术研究所 | Portable binocular pupil detection device |
| CN104739364A (en) * | 2015-03-14 | 2015-07-01 | 中国科学院苏州生物医学工程技术研究所 | Binocular pupil light reflex tracking system |
| CN104739364B (en) * | 2015-03-14 | 2017-01-11 | 中国科学院苏州生物医学工程技术研究所 | Binocular pupil light reflex tracking system |
| CN105520713A (en) * | 2015-11-30 | 2016-04-27 | 中国科学院苏州生物医学工程技术研究所 | Binocular pupil light reflex measuring equipment |
| CN105433899A (en) * | 2015-11-30 | 2016-03-30 | 中国科学院苏州生物医学工程技术研究所 | Pupil detection device |
| CN107358224A (en) * | 2017-08-18 | 2017-11-17 | 北京工业大学 | A kind of method that iris outline detects in cataract operation |
| CN110251074A (en) * | 2019-06-19 | 2019-09-20 | 重庆市中医院 | Multifunctional medical detection system |
| CN110251074B (en) * | 2019-06-19 | 2021-10-08 | 重庆市中医院 | Multifunctional medical detection system |
| CN113405505A (en) * | 2020-03-16 | 2021-09-17 | 同方威视技术股份有限公司 | Method and device for determining distance and height based on multiple sensors |
| CN111772575A (en) * | 2020-06-02 | 2020-10-16 | 岭南师范学院 | LED (light emitting diode) -based optical nondestructive special children detector and detection method |
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