CN105433899A - Pupil detection device - Google Patents

Pupil detection device Download PDF

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Publication number
CN105433899A
CN105433899A CN201510861573.8A CN201510861573A CN105433899A CN 105433899 A CN105433899 A CN 105433899A CN 201510861573 A CN201510861573 A CN 201510861573A CN 105433899 A CN105433899 A CN 105433899A
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pupil
image
light source
stimulating light
chip microcomputer
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CN201510861573.8A
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Chinese (zh)
Inventor
付威威
顾可可
董月芳
许一
刘志颖
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Suzhou Institute of Biomedical Engineering and Technology of CAS
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Suzhou Institute of Biomedical Engineering and Technology of CAS
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Priority to CN201510861573.8A priority Critical patent/CN105433899A/en
Publication of CN105433899A publication Critical patent/CN105433899A/en
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Abstract

The invention discloses a pupil detection device. The pupil detection device comprises a binocular pupil imaging system, a pupil tracking and measuring system and a display screen, wherein the binocular pupil imaging system comprises a first infrared illumination light source, a second infrared illumination light source, a first stimulation light source, a second stimulation light source, a sighting mark device, a baffle, a reflection mirror, an infrared filter, a lens and an infrared camera. The pupil tracking and measuring system comprises a single-chip microcomputer. Time of the stimulation light sources of the device can be regulated, the device accuracy is high, two pupils conducts imaging completely synchronously, the pupil tracking and measuring algorithm precision is high, measurement can be rapidly conducted, and use is convenient.

Description

Pupil detection equipment
Technical field
The present invention relates to pupillometry technical field, be specifically related to a kind of pupil detection equipment.
Background technology
Eyes are the most important sensory organ of human perception external information, and the still visual manner that in the consciousness such as vision, olfactory sensation, sense of touch, the sense of taste, audition, human brain impression is the most directly perceived, the amount of receiving information is maximum, accounts for human body from 70% of extraneous receipt message.And in human visual function, pupil has important science and value of clinical studies due to its special photonasty.Common people's pupil diameter variable, in 2mm-8mm, presents different sizes at different age levels, simultaneously also can shrink due to the impact of disease or medicine or expand.
Light is penetrated and is at the moment caused contracted pupil, claims luminous reflectance.Divide direct, consensual reflex two kinds.Penetrate at a glance with illumination, cause illuminated eye contracted pupil to claim direct light reflex.Illumination is penetrated at a glance, causes another eye pupil hole to reduce title consensual reflex simultaneously.Afferent pupillary disturbance refers to the pathological changes being positioned at retina, optic nerve, optic chiasma, tractus opticus or tectum of midbrain proparea, such as retina from, optic neuritis, repressive optic neuropathy etc., optical stimulus signal is imported into be obstructed, can not normally reach pupil movement maincenter, cause reaction of pupil to light to decline.If only there is afferent pupillary disturbance and another emmetropia, or two afferent pupillary disturbance degree are asymmetric, are called neuroretinal rim area at a glance.
RAPD reflects the asymmetric defect of one-sided or bilateral of pupil afferent pathway, and common detection method has alternately exposure experiments to light, neutral-density filter method, three seconds batch technique, inclining test method and Pupillometer inspection techniques.The most frequently used method of at present its clinical examination is alternately exposure experiments to light.
Examinee enters darkroom, and dark adaptation 5 minutes, watches front attentively.First check pupil of both eyes size and record before inspection, avoid the situation originally just having pupil of both eyes not wait, the judgement after impact.Examiner is about 25cm place apart from examinee, makes light source with a 3V concentration torch, is placed in the optical axis slightly below, apart from eye 3 ~ 5cm, every irradiates about 1 second, then moves to rapidly another eye, alternately mobile between two with stable frequency, observe and compare the direct light reflex of pupil of both eyes.If right eye is strong eye, left eye is the trouble eye of the afferent pupillary disturbance of relative property.When irradiating right eye with pocket lamp, pupil of both eyes reduces, and suffers from eye pupil hole and reduces due to indirect reference; Moving pocket lamp subsequently impinges upon on left eye, and pupil of both eyes does not reduce, because of the afferent pupillary disturbance of left eye; Alternately irradiate eyes with 1 second gap, strong eye contracted pupil, suffers from eye platycoria.
The shortcoming of existing checkout facility and method is:
1. existing alternately exposure experiments to light uses pocket lamp to stimulate and naked-eye observation, can only judge whether roughly to there is RAPD, estimates reaction of pupil to light change, cannot carry out objective, quantitatively, accurately measure, comprise pupil radium, centroid position etc.;
2. manual method detects RAPD and can only observe state at a glance simultaneously, easily ignores another eye state, thus easily causes error in judgement;
3. existing alternately exposure experiments to light method cannot ensure that the incentive condition of eyes is identical, makes easily to occur false RAPD or false-negative result during inspection;
4. traditional instrument for examining pupil equipment, a lot of test link needs artificial participation, and manually-operated diversity and subjective judgment all may cause test inaccurate, and require that the fitness of experimenter is very high, can bring sticky feeling to experimenter;
5. existing pupillometry software poor real, therefore certainty of measurement is limited;
6. existing binocular pupil detection equipment mostly is bench device, and common handheld device generally adopts two image collecting devices to gather, and the synchronicity of collection is difficult to ensure card, and volume is bigger than normal, and mechanism is complicated, and cost is higher.
Summary of the invention
The object of the invention is to, a kind of pupil detection equipment is provided, can solve that the accuracy of pupillometry that prior art exists is low, the poor synchronization of the pupil image of two eyes, measurement is convenient not, cost is high problem.
For this purpose, the present invention proposes a kind of pupil detection equipment, comprising:
Binocular pupil image system, pupil tracing measuring system and display screen; Wherein,
Described binocular pupil image system comprises the first infrared illumination source, second infrared illumination source, first stimulating light source, second stimulating light source, visual testing sign device, baffle plate, reflecting mirror, infrared fileter, camera lens and infrared camera, described pupil tracing measuring system comprises single-chip microcomputer, described first infrared illumination source is connected with described single-chip microcomputer with the second infrared illumination source, by described Single-chip Controlling opening and closing, described first stimulating light source is connected with described single-chip microcomputer with the second stimulating light source, stimulated in turn by described Single-chip Controlling, described Infrared Detectors is connected with described single-chip microcomputer, the collection of pupil image is carried out by described Single-chip Controlling,
Described first infrared illumination source, second infrared illumination source, the bright spot that the position of the first stimulating light source and the second stimulating light source all can make himself be formed at person's inside ofeye to be measured drops on pupil inside, described visual testing sign device is away from described person's eyes to be measured, and be positioned at described person to be measured two mid-eye dead ahead predeterminable range places, described baffle plate is between described two eyes, its position can make described first stimulating light source and the second stimulating light source stimulate described two eyes simultaneously respectively and not interfere with each other, described reflecting mirror is connect after described baffle plate, described reflecting mirror is positioned at described two mid-eye dead aheads, described camera lens is connect after described infrared fileter, described infrared camera is connect after described camera lens, the light that described first infrared illumination source sends and the light that described second infrared illumination source sends are reflected by the left eye of described person to be measured and right eye respectively, reflection ray is after described reflecting mirror reflection, enter described infrared fileter, and through described camera lens, be imaged on described infrared camera,
Described single-chip microcomputer, for obtaining described first infrared illumination source, the second infrared illumination source is luminous, and described first stimulating light source, the pupil image of described two eyes that described infrared camera gathers under a stimulating light source luminance in the second stimulating light source, described pupil image is processed, obtain the radius of pupil and the position of barycenter in described pupil image, and give described display screen by the location transmission of the radius of described pupil image, pupil and barycenter, to make described display screen, the data that described single-chip microcomputer transmits are shown.
The beneficial effect of equipment of the present invention is:
1, need the artificial link participated in less, pupil tracing measuring system arithmetic accuracy is high, real-time, and software system is stablized, and this device measuring result is accurate, directly perceived, can promptly show on a display screen;
2, be configured with visual testing sign device, in measuring process, human eye can annotate sighting target, avoids Rotation of eyeball to cause measurement result inaccurate;
3, adopt the opening and closing of Single-chip Controlling infrared illumination source and the stimulation in turn of stimulating light source, can ensure that the incentive condition of eyes is identical, make not easily to occur false RAPD or false-negative result during inspection;
4, the image capture device of this equipment only adopts an infrared camera to gather pupil of both eyes, while guaranteeing certainty of measurement, ensure that the synchronicity of collection, saves cost simultaneously, reduces volume, ensures the portability of equipment;
5, substantially can not bring excessive sense of discomfort to measured in measuring process, Consumer's Experience sense is stronger.
Accompanying drawing explanation
The part run schematic diagram of Fig. 1 involved by a kind of pupil detection equipment of the present invention;
Fig. 2 is the front view of pupil detection equipment of the present invention;
Fig. 3 is the rearview of the equipment shown in Fig. 2;
Fig. 4 is the side view of the equipment shown in Fig. 2;
Fig. 5 is the top view of the equipment shown in Fig. 2;
The schematic flow sheet of Fig. 6 involved by the pupil tracing measuring system of a kind of pupil detection equipment of the present invention.
Detailed description of the invention
For making the object of the embodiment of the present invention, technical scheme and advantage clearly, below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly described, obviously, described embodiment is the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Referring to Fig. 1, the present embodiment discloses a kind of pupil detection equipment, comprising:
Binocular pupil image system 1, pupil tracing measuring system 2 and display screen; Wherein,
Described binocular pupil image system 1 comprises the first infrared illumination source, second infrared illumination source, first stimulating light source, second stimulating light source, visual testing sign device, baffle plate, reflecting mirror, infrared fileter, camera lens and infrared camera, described pupil tracing measuring system 2 comprises single-chip microcomputer, described first infrared illumination source is connected with described single-chip microcomputer with the second infrared illumination source, by described Single-chip Controlling opening and closing, described first stimulating light source is connected with described single-chip microcomputer with the second stimulating light source, stimulated in turn by described Single-chip Controlling, described Infrared Detectors is connected with described single-chip microcomputer, the collection of pupil image is carried out by described Single-chip Controlling,
Described first infrared illumination source, second infrared illumination source, the bright spot that the position of the first stimulating light source and the second stimulating light source all can make himself be formed at person's inside ofeye to be measured drops on pupil inside, described visual testing sign device is away from described person's eyes to be measured, and be positioned at described person to be measured two mid-eye dead ahead predeterminable range places, described baffle plate is between described two eyes, its position can make described first stimulating light source and the second stimulating light source stimulate described two eyes simultaneously respectively and not interfere with each other, described reflecting mirror is connect after described baffle plate, described reflecting mirror is positioned at described two mid-eye dead aheads, described camera lens is connect after described infrared fileter, described infrared camera is connect after described camera lens, the light that described first infrared illumination source sends and the light that described second infrared illumination source sends are reflected by the left eye of described person to be measured and right eye respectively, reflection ray is after described reflecting mirror reflection, enter described infrared fileter, and through described camera lens, be imaged on described infrared camera,
Described single-chip microcomputer, for obtaining described first infrared illumination source, the second infrared illumination source is luminous, and described first stimulating light source, the pupil image of described two eyes that described infrared camera gathers under a stimulating light source luminance in the second stimulating light source, described pupil image is processed, obtain the radius of pupil and the position of barycenter in described pupil image, and give described display screen by the location transmission of the radius of described pupil image, pupil and barycenter, to make described display screen, the data that described single-chip microcomputer transmits are shown.
This equipment stimulating light source time is adjustable, and equipment degree of accuracy is high, the imaging of two pupil Complete Synchronizations, and pupil tracing Measurement Algorithm precision is high, can Quick Measurement, easy to use.
Pupil detection equipment described in the embodiment of the present invention, need the artificial link participated in less, pupil tracing measuring system arithmetic accuracy is high, real-time, and software system is stablized, and this device measuring result is accurate, directly perceived, can promptly show on a display screen; Be configured with visual testing sign device, in measuring process, human eye can annotate sighting target, avoids Rotation of eyeball to cause measurement result inaccurate; Adopt the opening and closing of Single-chip Controlling infrared illumination source and the stimulation in turn of stimulating light source, can ensure that the incentive condition of eyes is identical, make not easily to occur false RAPD or false-negative result during inspection; The image capture device of this equipment only adopts an infrared camera to gather pupil of both eyes, while guaranteeing certainty of measurement, ensure that the synchronicity of collection, saves cost simultaneously, reduces volume, ensures the portability of equipment; Substantially can not bring excessive sense of discomfort to measured in measuring process, Consumer's Experience sense is stronger.
Alternatively, in another embodiment of pupil detection equipment of the present invention, described Single-chip Controlling, for controlling the light illumination of described first stimulating light source and the second stimulating light source, optical source wavelength, stimulation time and stimulus frequency in turn, described first stimulating light source and the second stimulating light source are provided with reflector.
Alternatively, in another embodiment of pupil detection equipment of the present invention, the stimulation time of described first stimulating light source and the second stimulating light source is 200ms, 400ms or 1000ms, and described stimulus frequency is in turn 1s, 2s or 3s.
Alternatively, in another embodiment of pupil detection equipment of the present invention, described single-chip microcomputer, for intercepting pupil region image from described pupil image, from described pupil region image, extract pupil edge image, calculate the radius of pupil and the position of barycenter in described pupil image according to described pupil edge image.
Alternatively, in another embodiment of pupil detection equipment of the present invention, described single-chip microcomputer, for estimating the center of pupil in described pupil image, carrying out the intercepting of pupil region image, obtaining pupil region image according to the center of described pupil.
Alternatively, in another embodiment of pupil detection equipment of the present invention, described single-chip microcomputer, positions the pupil region in described pupil image for the center according to described pupil, carry out the intercepting of pupil region image according to positioning result, obtain pupil region image.
Alternatively, in another embodiment of pupil detection equipment of the present invention, described single-chip microcomputer, for the center according to pupil in the first frame pupil image, the pupil region in described first frame pupil image is positioned, the intercepting of pupil region image is carried out according to the positioning result of the pupil region in described first frame pupil image, obtain the pupil region image in described first frame pupil image
For positioning the pupil region in the second frame pupil image according to the positioning result of the pupil region in described first frame pupil image, carry out the intercepting of pupil region image according to the positioning result of the pupil region in described second frame pupil image, obtain the pupil region image in described second frame pupil image.
Alternatively, in another embodiment of pupil detection equipment of the present invention, described single-chip microcomputer, also for before extract pupil edge image from described pupil region image, carries out noise reduction process to described pupil region image.
Alternatively, in another embodiment of pupil detection equipment of the present invention, described single-chip microcomputer, for by carrying out carrying out image threshold segmentation to described pupil region image, extracts pupil edge image from described pupil region image.
Alternatively, in another embodiment of pupil detection equipment of the present invention, described single-chip microcomputer, also for the radial difference of pupil and the position deviation of barycenter of two eyes according to the radius of the pupil in described pupil image and the position calculation of barycenter, according to the radial difference of pupil and the position deviation of barycenter of described two eyes, and the disease mapping table preset obtains the state of an illness result of the neuroretinal rim area of described person to be measured, wherein, described disease mapping table comprises a left side, the radial difference field of the pupil of right eye eyeball, left, the position deviation field of the barycenter of the pupil of right eye eyeball and the state of an illness result of neuroretinal rim area.
In the embodiment of the present invention, the radius value obtained is stimulated to calculate the position deviation of radial difference and barycenter according to carrying out separately stimulating light source to two eyes, the state of an illness result of neuroretinal rim area is obtained according to the position deviation of radial difference and barycenter, in addition, other embodiment can also be had.For left eye, during independent stimulation left eye, obtain the radius of pupil of left eye and the position of barycenter, then right eye is stimulated separately, obtain the radius of pupil of left eye and the position of barycenter, according to the radius of pupil of left eye to obtain for twice and the radial difference of position calculation pupil of left eye of barycenter and the position deviation of barycenter, the state of an illness result that corresponding disease mapping table obtains the neuroretinal rim area of person's left eye to be measured is searched according to the radial difference of pupil of left eye and the position deviation of barycenter, wherein, corresponding disease mapping table comprises the radial difference field of pupil of left eye, the position deviation field of the barycenter of pupil of left eye and the state of an illness result of neuroretinal rim area.
Below in conjunction with accompanying drawing, the present invention is described in further detail:
The part run schematic diagram of accompanying drawing 1 involved by structure of the present invention, comprises binocular pupil image system and pupil tracing measuring system.Wherein, imaging system comprises two infrared illumination source, two stimulating light sources, visual testing sign device, baffle plate, reflecting mirror, infrared fileter, camera lens and infrared cameras, and pupil tracing measuring system comprises single-chip microcomputer.Light source is connected with single-chip microcomputer with infrared camera, is carried out the input and output of control and data by single-chip microcomputer.Single-chip microcomputer carries out tracking to the image of infrared camera collection and measures, and carries out analyzing and processing to measurement result, can also export terminal to by wireless (as WIFI, bluetooth).The infrared illumination source illumination of binocular pupil image internal system is fixed, by Single-chip Controlling; Stimulating light source regulates by single-chip microcomputer, select different light illuminations according to user's request and stimulate wavelength, different stimulation times and eyes can be selected according to demand to stimulate inversion frequency simultaneously, as: stimulating light source stimulation time can select 200ms, 400ms and 1000ms, and eyes stimulate inversion frequency to select 1s, 2s and 3s.
Pupil image and measurement result are shown on display screen, and measurement result can comprise (comprising pupil deviation of mass center change curve and radial difference change curve) such as binocular pupil change curve (comprising pupil centroid position change curve and radius change curve), pupil of both eyes comparison curvess.
The output of pupil tracing measuring system supported data and the output of measurement report, export result to terminal, so that further inventory analysis.
Accompanying drawing 2 to 5 is a kind of light channel structure schematic diagram of the present invention, is respectively front view, rearview, side view and top view,
The present invention can be made into hand-held measurement device, binocular pupil image system and pupil tracing measuring system are arranged on device interior, image collecting device in portable equipment only comprises an infrared camera 19, ensure the synchronicity gathered, save cost simultaneously, reduce volume, ensure the portability of equipment, directly controlled to gather by single-chip microcomputer 8; Camera lens 18 and infrared fileter 17 are installed before camera;
Measured's right and left eyes is placed on 6,7 positions respectively, is thrown light on by infrared illumination source 10 and infrared illumination source 12, and is stimulated by stimulating light source 11 and stimulating light source 13; The intensity of stimulating light source, time and eyes stimulate inversion frequency etc. to be controlled by single-chip microcomputer 8; Human eye pupil image is received by infrared camera after turning back via reflecting mirror 15;
Light source position is as far as possible near middle, and the luminous point making it be formed in human eye drops on pupil center as far as possible, in order to avoid affect certainty of measurement, also will note the image-receptive that can not affect infrared camera simultaneously;
Reflector can be added on stimulating light source 11 and 13, reduce its angle of divergence, strengthen stimulation;
Sighting target 16 is positioned at human eye sight front, helps human eye fixed position, makes its pupil imaging in fixed position, improves certainty of measurement;
Baffle plate 14 is arranged on two centres, and interfering with each other of isolated right and left eyes infrared illumination source and stimulating light source, improves certainty of measurement; Its length is selected should consider to stop that right and left eyes interferes with each other, and considers the reception not hindering infrared camera to image again;
Be provided with display screen 5 above equipment handle, display screen, by single-chip microcomputer input picture and measurement result, shows pupil image and the measurement result of collected by camera;
Inside, equipment handle position is provided with single-chip microcomputer 8 and power supply 9, the input and output of camera control and collection are responsible for by single-chip microcomputer, be responsible for the control of various light source, be responsible for the display driver etc. of display screen, be connected with infrared camera, light source, display screen with data wire by control line.Power supply 9 provides power supply to camera and single-chip microcomputer, and power supply supports alternating current charging, easy to use;
Infrared illumination source, stimulating light source are by portable equipment by Single-chip Controlling, and the button namely on handheld apparatus, by the button on handheld apparatus, selects different stimulation wavelength, source stimulating time, stimulus intensity and eyes to stimulate inversion frequency.As shown in Figure 2, there is button 0,1,2,3,4 equipment handle position, 0 is facility switching button, 1 is button up and down, and for selecting different mode and switching, 2 is infrared light supply button, 3 is stimulating light source button, 4 is pupil tracing button, and its mid-infrared light source button, stimulating light source button and pupil tracing button respectively install one group about handle, facilitate right-hand man all can operate.
Accompanying drawing 6 is the handling process schematic diagram of pupil tracing measuring system of the present invention, after system input pupil image, gray feature first based on pupil image estimates pupil of both eyes center, carry out the oculopupillary just location of people, carry out the intercepting of pupil image, remove the remainder especially interference of bridge of the nose part inactive area between eyes, improve measuring speed.Again the pretreatment such as the elimination of the noise such as bright spot, eyelashes are carried out to the pupil image region after intercepting.Threshold segmentation is carried out to pretreated image, extracts pupil edge, calculate barycenter and radius, compare the data difference of pupil of both eyes.Limit next frame pupil position fast by tracing algorithm and accelerate detection speed, the real-time positioning realizing pupil is followed the trail of.To be detectedly to complete, will the data difference of pupil of both eyes under simple eye stimulation be drawn, according to the relation quantitative analysis state of an illness of itself and RAPD.
Portable construction of the present invention, small and exquisite, image collecting device only adopts an infrared camera to carry out binocular images collection, ensures the synchronicity that right and left eyes gathers, and can save cost, reduce volume, ensure its portability; Support binocular pupillometry, pupillary light reflex measurement result can be obtained; Portable equipment portability is strong, can be applicable to the occasion that the natural conditions such as first aid, ward, even field are poor; Equipment flexibility ratio is high, supports wireless or wired by measurement result output data terminal, meets measurement result and stores and printing demand; The stimulating light source Wavelength tunable of measurement device, stimulus intensity, stimulation time, eyes stimulate inversion frequency adjustable with the demand meeting different situations; Pupil detection Trancking Software algorithm can draw the fiducial value of pupil of both eyes, carries out the judgement of RAPD symptom.
Although describe embodiments of the present invention by reference to the accompanying drawings, but those skilled in the art can make various modifications and variations without departing from the spirit and scope of the present invention, such amendment and modification all fall into by within claims limited range.

Claims (10)

1. a pupil detection equipment, is characterized in that, comprising:
Binocular pupil image system, pupil tracing measuring system and display screen; Wherein,
Described binocular pupil image system comprises the first infrared illumination source, second infrared illumination source, first stimulating light source, second stimulating light source, visual testing sign device, baffle plate, reflecting mirror, infrared fileter, camera lens and infrared camera, described pupil tracing measuring system comprises single-chip microcomputer, described first infrared illumination source is connected with described single-chip microcomputer with the second infrared illumination source, by described Single-chip Controlling opening and closing, described first stimulating light source is connected with described single-chip microcomputer with the second stimulating light source, stimulated in turn by described Single-chip Controlling, described Infrared Detectors is connected with described single-chip microcomputer, the collection of pupil image is carried out by described Single-chip Controlling,
Described first infrared illumination source, second infrared illumination source, the bright spot that the position of the first stimulating light source and the second stimulating light source all can make himself be formed at person's inside ofeye to be measured drops on pupil inside, described visual testing sign device is away from described person's eyes to be measured, and be positioned at described person to be measured two mid-eye dead ahead predeterminable range places, described baffle plate is between described two eyes, its position can make described first stimulating light source and the second stimulating light source stimulate described two eyes simultaneously respectively and not interfere with each other, described reflecting mirror is connect after described baffle plate, described reflecting mirror is positioned at described two mid-eye dead aheads, described camera lens is connect after described infrared fileter, described infrared camera is connect after described camera lens, the light that described first infrared illumination source sends and the light that described second infrared illumination source sends are reflected by the left eye of described person to be measured and right eye respectively, reflection ray is after described reflecting mirror reflection, enter described infrared fileter, and through described camera lens, be imaged on described infrared camera,
Described single-chip microcomputer, for obtaining described first infrared illumination source, the second infrared illumination source is luminous, and described first stimulating light source, the pupil image of described two eyes that described infrared camera gathers under a stimulating light source luminance in the second stimulating light source, described pupil image is processed, obtain the radius of pupil and the position of barycenter in described pupil image, and give described display screen by the location transmission of the radius of described pupil image, pupil and barycenter, to make described display screen, the data that described single-chip microcomputer transmits are shown.
2. pupil detection equipment according to claim 1, it is characterized in that, described Single-chip Controlling, for controlling the light illumination of described first stimulating light source and the second stimulating light source, optical source wavelength, stimulation time and stimulus frequency in turn, described first stimulating light source and the second stimulating light source are provided with reflector.
3. pupil detection equipment according to claim 2, is characterized in that, the stimulation time of described first stimulating light source and the second stimulating light source is 200ms, 400ms or 1000ms, and described stimulus frequency is in turn 1s, 2s or 3s.
4. pupil detection equipment according to claim 1, it is characterized in that, described single-chip microcomputer, for intercepting pupil region image from described pupil image, from described pupil region image, extract pupil edge image, calculate the radius of pupil and the position of barycenter in described pupil image according to described pupil edge image.
5. pupil detection equipment according to claim 4, is characterized in that, described single-chip microcomputer, for estimating the center of pupil in described pupil image, carrying out the intercepting of pupil region image, obtain pupil region image according to the center of described pupil.
6. pupil detection equipment according to claim 5, it is characterized in that, described single-chip microcomputer, for the center according to described pupil, the pupil region in described pupil image is positioned, carry out the intercepting of pupil region image according to positioning result, obtain pupil region image.
7. pupil detection equipment according to claim 5, it is characterized in that, described single-chip microcomputer, for the center according to pupil in the first frame pupil image, the pupil region in described first frame pupil image is positioned, the intercepting of pupil region image is carried out according to the positioning result of the pupil region in described first frame pupil image, obtain the pupil region image in described first frame pupil image
For positioning the pupil region in the second frame pupil image according to the positioning result of the pupil region in described first frame pupil image, carry out the intercepting of pupil region image according to the positioning result of the pupil region in described second frame pupil image, obtain the pupil region image in described second frame pupil image.
8. pupil detection equipment according to claim 4, is characterized in that, described single-chip microcomputer, also for before extract pupil edge image from described pupil region image, carries out noise reduction process to described pupil region image.
9. pupil detection equipment according to claim 4, is characterized in that, described single-chip microcomputer, for by carrying out carrying out image threshold segmentation to described pupil region image, from described pupil region image, extracts pupil edge image.
10. pupil detection equipment according to claim 1, it is characterized in that, described single-chip microcomputer, also for the radial difference of pupil and the position deviation of barycenter of two eyes according to the radius of the pupil in described pupil image and the position calculation of barycenter, according to the radial difference of pupil and the position deviation of barycenter of described two eyes, and the disease mapping table preset obtains the state of an illness result of the neuroretinal rim area of described person to be measured, wherein, described disease mapping table comprises a left side, the radial difference field of the pupil of right eye eyeball, left, the position deviation field of the barycenter of the pupil of right eye eyeball and the state of an illness result of neuroretinal rim area.
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