CN101181487A - 一种内服治疗骨质疏松的中药组合物 - Google Patents
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Abstract
本发明公开了一种内服治疗骨质疏松的中药组合物，制成有效成分的原料药按下述重量为：仙茅6克，黄柏10克，巴戟天10克，淫羊藿10克，草乌6克，当归12克，川芎12克，炙甘草5克，葛根10克，知母10克。水煎服，一日一剂，没剂分两次口服。本发明诸药合用，阴阳双补，标本同治，温而不燥，使用后不仅可较快地缓解疼痛，而且能逐渐改善骨质疏松症的其他症状，提高机体抗病能力。
Description
技术领域
本发明涉及一种内服治疗骨质疏松的中药组合物，属中药领域。
背景技术
骨质疏松是一种涉及到全身骨骼系统长期、持续的丢失骨所形成的疾病。骨质疏松症是一种全身性疾病，其特点是骨量减少和骨组织的微细结构破坏，导致骨脆性增加，容易发生骨折。
引起骨质疏松的原因：雌激素会刺激骨质的形成及抑制骨质的分解。妇女若因卵巢切除或更年期，便雌激素停止或減少分泌，就會加速骨质疏松；钙摄取不足或常吃高蛋白、高盐的食物或嗜烟、嗜酒；缺少运动、少晒太阳陽；長期服用类固醇、抗癌药、利尿剂、抗凝血剂、胃药或止痛药者；骨质疏松有一定的遗传性。
骨质疏松的症状以腰背痛多见，骨支撑人体及抵抗外力的功能减弱，脆性增加，变得容易骨折。当骨密度严重降低时，连咳嗽、开窗、弯腰端水这样的小动作也可能导致骨折。
中医治疗骨质疏松特点是辨证论治，整体调节，应用补肾壮骨，健脾助运，活血化淤等疗法，常能取得较满意的效果，使引起机体失衡的多重因素得以纠正。
发明内容
本发明人经过多年的临床实践，充分发挥中药治疗的长处，总结研制出了该种内服治疗骨质疏松的中药组合物。
本发明是通过下述技术方案实现的：该种内服治疗骨质疏松的中药组合物，其特征在于，制成有效成分的原料药按下述重量为：仙茅6克，黄柏10克，巴戟天10克，淫羊藿10克，草乌6克，当归12克，川芎12克，炙甘草5克，葛根10克，知母10克。
用法：水煎服，一日一剂，没剂分两次口服。
仙茅：温肾阳，壮筋骨。 治阳萎精冷，小便失禁，崩漏，心腹冷痛，腰脚冷痹，痈疽，瘰疬，阳虚冷泻。
黄柏：寒，归肾经，可坚阴治疗骨蒸潮热。
淫羊藿：补肾壮阳，祛风除湿。治阳痿不举，小便淋沥，筋骨挛急，半身不遂，腰膝无力，风湿痹痛，四肢不仁。
草乌：祛风除湿，温经止痛。用于风寒湿痹、关节疼痛、心腹冷痛、寒疝作痛、麻醉止痛。
巴戟天：补肾阳，壮筋骨，祛风湿。治阳痿，少腹冷痛，小便不禁，子宫虚冷，风寒湿痹，腰膝酸痛。
当归：补血和血，调经止痛，润燥滑肠。治月经不调，经闭腹痛，癥瘕结聚，崩漏；血虚头痛，眩晕，痿痹；肠燥便难，赤痢后重；痈疽疮窃，跌扑损伤。
川芎：行气开郁，法风燥湿，活血止痛。治风冷头痛旋晕，胁痛腹疼，寒痹筋挛，经闭，难产，产后瘀阻块痛，痈疽疮疡。
炙甘草：和中缓急，润肺，解毒，调和诸药。炙用治脾胃虚弱，食少，腹痛便溏，劳倦发热，心悸，肺痿咳嗽。
葛根：升阳解肌，透疹止泻，除烦止渴，治伤寒，温热头痛项强，烦热消渴。
知母：滋阴降火，润燥滑肠。治烦热消渴，骨蒸劳热，肺热咳嗽，大便燥结，小便不利。
方中淫羊藿辛甘温归肝肾经，可补肾壮阳、通络止痛，黄柏苦寒亦归肾经，可坚阴治疗骨蒸潮热，二药合用，阴阳双补，相辅相成，以治根本，共为君药；仙茅、巴戟天均为温性归肾经，以助淫羊藿补肾壮阳、知母苦寒坚阴，可助黄柏坚阴降虚热，三药在方中为臣药；葛根、草乌通络止痛、温经散寒，当归、川芎养血活血、化瘀止痛，四者合用，止痛以急治其标，故为佐药；炙甘草既可健脾以补肾，又能缓解二乌之毒性，为使药。纵观全方，诸药合用，阴阳双补，标本同治，温而不燥，使用后不仅可较快地缓解疼痛，而且能逐渐改善骨质疏松症的其他症状，提高机体抗病能力。
研究过程中将骨质疏松症患者100人，分为本发明药物组组和西药对照组。两组经西医诊断排除心脑血管及其他代谢性疾病，并在病情、病程、性别及一般情况等方面均无明显差异。本发明药物组给与本发明药物一日一剂；西药对照组口服乳酸钙两片，每天3次。治疗3个疗程后，本发明药物组疗效明显优于西药对照组(p＜0.01)。在治疗后的追踪观察中，未发现类似雌激素引起的副作用，肝肾功能及血象化验等亦未见异常，表明中药骨松康具有调节内分泌，促进钙质吸收的功能。
具体实施方式
例一：一种内服治疗骨质疏松的中药组合物，其特征在于，制成有效成分的原料药按下述重量为：仙茅6克，黄柏10克，巴戟天10克，淫羊藿10克，草乌6克，当归12克，川芎12克，炙甘草5克，葛根10克，知母10克。
用法：水煎服，一日一剂，没剂分两次口服。
Claims (1)
1.一种内服治疗骨质疏松的中药组合物，其特征在于，制成有效成分的原料药按下述重量为：仙茅6克，黄柏10克，巴戟天10克，淫羊藿10克，草乌6克，当归12克，川芎12克，炙甘草5克，葛根10克，知母10克。
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101708266B (zh) * | 2009-12-14 | 2011-04-27 | 耿爱芝 | 一种内服治疗骨质疏松的中药汤剂 |
| CN104095914A (zh) * | 2013-04-02 | 2014-10-15 | 上海圣赐康生物医药科技有限公司 | 一种增加骨密度的骨泰胶囊配方及其制备方法 |
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| CN1059115C (zh) * | 1997-10-06 | 2000-12-06 | 苏顺兴 | 一种治疗骨质疏松症的药物组合物 |
| CN1323677C (zh) * | 2004-06-03 | 2007-07-04 | 陈根生 | 治疗骨质疏松症的药物 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101708266B (zh) * | 2009-12-14 | 2011-04-27 | 耿爱芝 | 一种内服治疗骨质疏松的中药汤剂 |
| CN104095914A (zh) * | 2013-04-02 | 2014-10-15 | 上海圣赐康生物医药科技有限公司 | 一种增加骨密度的骨泰胶囊配方及其制备方法 |
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