CN101177700B - 生产具有预定的翻译后修饰的蛋白质的方法和手段 - Google Patents
生产具有预定的翻译后修饰的蛋白质的方法和手段 Download PDFInfo
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- CN101177700B CN101177700B CN2007101494988A CN200710149498A CN101177700B CN 101177700 B CN101177700 B CN 101177700B CN 2007101494988 A CN2007101494988 A CN 2007101494988A CN 200710149498 A CN200710149498 A CN 200710149498A CN 101177700 B CN101177700 B CN 101177700B
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Toxicology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NLPCT/NL01/00792 | 2001-10-29 | ||
PCT/NL2001/000792 WO2003050286A1 (en) | 2001-10-29 | 2001-10-29 | Methods and means for producing proteins with predetermined post-translational modifications |
PCT/NL2002/000257 WO2003089468A1 (en) | 2002-04-19 | 2002-04-19 | Methods and means for producing proteins with predetermined post-translational modifications |
NLPCT/NL02/00257 | 2002-04-19 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB028216903A Division CN100347306C (zh) | 2001-10-29 | 2002-10-29 | 生产具有预定的翻译后修饰的蛋白质的方法和手段 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101177700A CN101177700A (zh) | 2008-05-14 |
CN101177700B true CN101177700B (zh) | 2012-03-21 |
Family
ID=19760777
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2007101494988A Expired - Fee Related CN101177700B (zh) | 2001-10-29 | 2002-10-29 | 生产具有预定的翻译后修饰的蛋白质的方法和手段 |
Country Status (7)
Country | Link |
---|---|
KR (3) | KR100692784B1 (es) |
CN (1) | CN101177700B (es) |
AU (1) | AU2002224199A1 (es) |
IL (1) | IL161674A0 (es) |
MX (1) | MXPA04003940A (es) |
WO (1) | WO2003050286A1 (es) |
ZA (1) | ZA200403209B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9244235B2 (en) | 2008-10-17 | 2016-01-26 | Foro Energy, Inc. | Systems and assemblies for transferring high power laser energy through a rotating junction |
TWI532495B (zh) * | 2009-10-05 | 2016-05-11 | 菲瑞茵國際中心股份有限公司 | 藥學製劑 |
CN102818896B (zh) * | 2011-06-09 | 2014-12-17 | 北京华大蛋白质研发中心有限公司 | 一种基于特异抗体的硝基化修饰位点的检测方法及特异识别scot硝基化位点的抗体 |
EP3382014A1 (en) * | 2017-03-29 | 2018-10-03 | CEVEC Pharmaceuticals GmbH | Recombinant glycoproteins with reduced antennary fucosylation |
US20230331798A1 (en) * | 2020-09-22 | 2023-10-19 | Jecho Laboratories, Inc. | Glycosylation-modified erythopoietin and use thereof |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5789247A (en) * | 1994-04-01 | 1998-08-04 | Ballay; Annick | Expression in non-tumoral human lymphoblastoid lines with an integrative vector |
WO1998044141A2 (en) * | 1997-03-27 | 1998-10-08 | The University Of British Columbia | Insect expression vectors |
WO2000063403A2 (en) * | 1999-04-15 | 2000-10-26 | Crucell Holland B.V. | Recombinant protein production in a human cell using sequences encoding adenovirus e1 protein |
-
2001
- 2001-10-29 AU AU2002224199A patent/AU2002224199A1/en not_active Abandoned
- 2001-10-29 WO PCT/NL2001/000792 patent/WO2003050286A1/en active Application Filing
-
2002
- 2002-10-29 KR KR1020047006311A patent/KR100692784B1/ko not_active IP Right Cessation
- 2002-10-29 KR KR1020067008077A patent/KR100737639B1/ko not_active IP Right Cessation
- 2002-10-29 KR KR1020067008079A patent/KR100602772B1/ko not_active IP Right Cessation
- 2002-10-29 MX MXPA04003940A patent/MXPA04003940A/es active IP Right Grant
- 2002-10-29 IL IL16167402A patent/IL161674A0/xx unknown
- 2002-10-29 CN CN2007101494988A patent/CN101177700B/zh not_active Expired - Fee Related
-
2004
- 2004-04-28 ZA ZA200403209A patent/ZA200403209B/en unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5789247A (en) * | 1994-04-01 | 1998-08-04 | Ballay; Annick | Expression in non-tumoral human lymphoblastoid lines with an integrative vector |
WO1998044141A2 (en) * | 1997-03-27 | 1998-10-08 | The University Of British Columbia | Insect expression vectors |
WO2000063403A2 (en) * | 1999-04-15 | 2000-10-26 | Crucell Holland B.V. | Recombinant protein production in a human cell using sequences encoding adenovirus e1 protein |
Non-Patent Citations (4)
Title |
---|
John E. Cronan.Biotination of Proteins in vivo.The Journal of Biological Chemistry265 18.1990,265(8),全文. |
John E. Cronan.Biotination of Proteins in vivo.The Journal of Biological Chemistry265 18.1990,265(8),全文. * |
John H. Pazur et al.Oligosaccharides as Immunodeterminants of Erythropoietin forTwo Sets of Anti-Carbohydrate Antibodies.Journal of Protein Chemistry19 8.2000,265(8),全文. |
John H. Pazur et al.Oligosaccharides as Immunodeterminants of Erythropoietin forTwo Sets of Anti-Carbohydrate Antibodies.Journal of Protein Chemistry19 8.2000,265(8),全文. * |
Also Published As
Publication number | Publication date |
---|---|
KR20060057648A (ko) | 2006-05-26 |
KR100692784B1 (ko) | 2007-03-12 |
KR100737639B1 (ko) | 2007-07-09 |
AU2002224199A1 (en) | 2003-06-23 |
MXPA04003940A (es) | 2004-11-29 |
IL161674A0 (en) | 2004-09-27 |
ZA200403209B (en) | 2005-01-14 |
WO2003050286A1 (en) | 2003-06-19 |
KR20050040824A (ko) | 2005-05-03 |
CN101177700A (zh) | 2008-05-14 |
KR100602772B1 (ko) | 2006-07-20 |
KR20060057647A (ko) | 2006-05-26 |
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