CN101175715B - 制备二苯基丙氨酸衍生物的不对称氢化反应 - Google Patents

制备二苯基丙氨酸衍生物的不对称氢化反应 Download PDF

Info

Publication number
CN101175715B
CN101175715B CN2006800170720A CN200680017072A CN101175715B CN 101175715 B CN101175715 B CN 101175715B CN 2006800170720 A CN2006800170720 A CN 2006800170720A CN 200680017072 A CN200680017072 A CN 200680017072A CN 101175715 B CN101175715 B CN 101175715B
Authority
CN
China
Prior art keywords
alkyl
phenyl
general formula
ligand
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2006800170720A
Other languages
English (en)
Chinese (zh)
Other versions
CN101175715A (zh
Inventor
L·T·博尔顿
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr Reddys Laboratories Ltd
Original Assignee
Dow Global Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Global Technologies LLC filed Critical Dow Global Technologies LLC
Publication of CN101175715A publication Critical patent/CN101175715A/zh
Application granted granted Critical
Publication of CN101175715B publication Critical patent/CN101175715B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/16—Preparation of optical isomers
    • C07C231/18—Preparation of optical isomers by stereospecific synthesis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
CN2006800170720A 2005-05-20 2006-05-09 制备二苯基丙氨酸衍生物的不对称氢化反应 Expired - Fee Related CN101175715B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68315005P 2005-05-20 2005-05-20
US60/683,150 2005-05-20
PCT/US2006/017978 WO2006127273A2 (en) 2005-05-20 2006-05-09 Asymmetric hydrogenation for the preparation of diphenylalanine derivatives

Publications (2)

Publication Number Publication Date
CN101175715A CN101175715A (zh) 2008-05-07
CN101175715B true CN101175715B (zh) 2011-04-13

Family

ID=37027602

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2006800170720A Expired - Fee Related CN101175715B (zh) 2005-05-20 2006-05-09 制备二苯基丙氨酸衍生物的不对称氢化反应

Country Status (6)

Country Link
EP (1) EP1885688B1 (enExample)
JP (1) JP5001263B2 (enExample)
CN (1) CN101175715B (enExample)
AT (1) ATE482182T1 (enExample)
DE (1) DE602006017064D1 (enExample)
WO (1) WO2006127273A2 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8680278B2 (en) * 2007-10-30 2014-03-25 Janssen Pharmaceutica Nv Enantioselective process for preparing a substituted alkanoic acid
JP2023535595A (ja) * 2020-07-28 2023-08-18 ジャズ ファーマシューティカルズ アイルランド リミテッド 縮合二環式ｒａｆ阻害剤のキラル合成

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5198548A (en) * 1992-01-30 1993-03-30 Warner-Lambert Company Process for the preparation of D(-) and L(+)-3,3-diphenylalanine and D(-) and L(+)-substituted 3,3-diphenylalanines and derivatives thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874629A (en) * 1996-06-12 1999-02-23 Merck & Co., Inc. Chiral bisphosphines
WO2002057278A1 (en) * 2001-01-19 2002-07-25 Chirotech Technology Limited Ligands and their use
JP2007537256A (ja) * 2004-05-11 2007-12-20 メルク　エンド　カムパニー　インコーポレーテッド Ｎ−スルホン化アミノ酸誘導体調製のためのプロセス

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5198548A (en) * 1992-01-30 1993-03-30 Warner-Lambert Company Process for the preparation of D(-) and L(+)-3,3-diphenylalanine and D(-) and L(+)-substituted 3,3-diphenylalanines and derivatives thereof

Also Published As

Publication number Publication date
JP2008540650A (ja) 2008-11-20
ATE482182T1 (de) 2010-10-15
WO2006127273A3 (en) 2007-03-22
DE602006017064D1 (de) 2010-11-04
EP1885688A2 (en) 2008-02-13
JP5001263B2 (ja) 2012-08-15
EP1885688B1 (en) 2010-09-22
WO2006127273A2 (en) 2006-11-30
CN101175715A (zh) 2008-05-07

Similar Documents

Publication Publication Date Title
JP3517265B2 (ja) 均一触媒の配位子としてのフェロセンジホスフィン
US6451727B2 (en) Catalysts for use in asymmetric synthesis comprising transition metals and chiral amine oxazolinyl ligands
US6492544B2 (en) Process for synthesis of enantiomerically enriched β-amino acids
JP4426012B2 (ja) エステル化合物および酸化合物の均一触媒によるエナンチオ選択的な水素添加のための方法および水素添加生成物の使用
JP6018046B2 (ja) ケトエステル類の水素化のためのプロセス
US20090221851A1 (en) Process for production of optically active aminophosphinylbutanoic acids
US6583312B2 (en) Process for preparing optically active trimethyllactic acid and its esters
WO2015178846A1 (en) Process for the preparation of chiral amines from prochiral ketones
CN101175715B (zh) 制备二苯基丙氨酸衍生物的不对称氢化反应
Zhou et al. Chiral 1-phenylethylamine-derived phosphine-phosphoramidite ligands for highly enantioselective Rh-catalyzed hydrogenation of β-(acylamino) acrylates: significant effect of substituents on 3, 3′-positions of binaphthyl moiety
US20090227805A1 (en) Axially Asymmetric Phosphorus Compound and Production Method Thereof
JP2005518339A (ja) 対応する（Ｚ）エナミドの鏡像選択的水素化によりエナンチオリッチなＮ−アシル−β−アミノ酸誘導体の製造方法
JPH0816078B2 (ja) 光学活性フェニル酢酸誘導体の製造法
JP2001026580A (ja) 光学活性１−アリール−１，２，３，４−テトラヒドロイソキノリン類の製造法
JP5147410B2 (ja) アクリル酸誘導体の遷移金属触媒不斉水素化方法および不斉遷移金属触媒反応用の新規な触媒系
US9340519B2 (en) Paracyclophane-based ligands, their preparation and use in catalysis
JP4658289B2 (ja) 光学活性な含フッ素アミノ酸誘導体の製造方法
WO2015178847A1 (en) Process for the preparation of chiral amines by asymmetric hydrogenation of prochiral oximes
US6998495B2 (en) Method for producing optically active 3,5-dihydroxycarboxylic acid derivative
US6020527A (en) Stereospecific isomerisation of allyl amines using chiral phosphorous ligands
US20040186314A1 (en) Process for the preparation of enantiomerically enriched n-acyl-beta-amino acid derivatives by enantioselective hydrogenation of the corresponding (z)-enamides
JP2007176824A (ja) 不斉還元方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
ASS Succession or assignment of patent right

Owner name: DR. REDDY S LABORATORIES(EUROPE) LTD.

Free format text: FORMER OWNER: THE DOW GLOBAL TECHNOLOGIES INC.

Effective date: 20100513

COR Change of bibliographic data

Free format text: CORRECT: ADDRESS; FROM: MICHIGAN, U.S. TO: EAST YORKSHIRE, U.K.

TA01 Transfer of patent application right

Effective date of registration: 20100513

Address after: The British East Yorkshire

Applicant after: Dr.reddy's Laboratories Ltd.

Address before: michigan

Applicant before: Dow Global Technologies Inc.

C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20110413

Termination date: 20130509