CN101172187A - Biological information electrical pulse sequence for needle treating instrument - Google Patents
Biological information electrical pulse sequence for needle treating instrument Download PDFInfo
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- CN101172187A CN101172187A CNA2007101336363A CN200710133636A CN101172187A CN 101172187 A CN101172187 A CN 101172187A CN A2007101336363 A CNA2007101336363 A CN A2007101336363A CN 200710133636 A CN200710133636 A CN 200710133636A CN 101172187 A CN101172187 A CN 101172187A
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Abstract
The invention relates to a biological information electrical impulse sequence. Organism acupuncture points are respectively stimulated through six acupuncture manipulations of even reinforcing and reducing, reinforcing or reducing by rotating the needle, reinforcing and reducing methods by lifting and thrusting needle, slow-rapid reinforcing-reducing, green dragon shaking tail stitch and turtle probing needling at point in the Chinese medical acupuncture, a group of importation information encoding actions induced on the spinal cord wide-dynamic neurons is respectively a group of voltage pulse sequences with chaos motion characteristic, the chaos degree according to the time sequence can be quantitatively described with a Lyapunov index. The electrical impulse sequence can accurately express and quantize biological information induced a variety of acupuncture needling manipulations, according to the feedback therapeutics principle of the biological information, the electrical impulse sequence including the biological information is applied to a needle treatment instrument, and the clinical curative effect of the needle treatment instrument can be improved.
Description
Technical field
The present invention relates to medical treatment and acupuncture instrument (also claiming " electric acupuncture and moxibustion instrument " or " electric acupuncture apparatus ") for health care, be specifically related to a kind of biological information electrical pulse sequence that is used for acupuncture instrument.This biological information electrical pulse sequence is to use famous expert's manipulation of acupuncture to cause by stimulation, and can converge all that cause from acupoint stimulation from organism and import the nerves reaction spike potential sequence of information coding into, the bio-electrical information that the various manipulations of acupuncture cause can accurately be expressed and quantize to this spike potential electrical pulse sequence, further improves the clinical efficacy of acupuncture instrument.
Background technology
Nerve electric stimulation therapy (peripheral nerve crude fibre electrical stimulating therapy, Transcuataneous electricalnerve stimulation) is with the electrotherapy method of specific low frequency pulse current input human body with treatment pain by skin.This is a kind of electrotherapy of rising the seventies in 20th century, receives effect preferably aspect pain relieving, has been proved kind of a maladjusted nervous system disease surplus 20 is had definite curative effect.Thereby (especially in country of Europe, the United States) obtained using widely clinically, and progressively generally used both at home and abroad.
The nerve electric stimulation therapy combines with the Chinese medicine acupuncture therapy and has formed the acupuncture electrical acupuncture method.This therapy sticks a needle into acupuncture points on the human body bring about the desired sensation after, on puncture needle, pass to little electric current near human biological electricity, utilize pin and the electricity two kinds of stimulations combine with disease preventing and treating.Its advantage be can replace the people do the long period continue handle the needle, save manpower.In the Chinese medicine acupuncture treatment, the widely-used of electric acupuncture apparatus arises from 70～eighties of last century, though the electric acupuncture apparatus kind of use is a lot of clinically at present, mainly contains following several types from principle:
1, buzzing formula electric acupuncture apparatus is a kind of electric bell oscillation principle that utilizes, and converts unidirectional current to pulse current, acts on human body at last.This pulse current waveform is narrower, as tip-like, and asymmetric.Because power consumption is big, and noise is arranged, seldom use now.
2, buck exchanges electric acupuncture apparatus, is a kind ofly voltage to be reduced to below the 25V through transformator with general mains ac power supply, is regulated and control output through resistance and potentiometer again, to obtain suitable stimulus intensity.Because frequency is non-adjustable, also seldom use now.
3, audio oscillation electric acupuncture apparatus is a kind of audio oscillator that utilizes, and in 20～200Hz scope, produces the sinusoidal wave electric acupuncture apparatus of frequency adjustable.Though frequency and output intensity are adjustable, waveform is simple, and curative effect is relatively poor, therefore also seldom uses at present.
4, transistor noise formula electric acupuncture apparatus.The power supply of this kind electric acupuncture apparatus is direct current 6V, and frequency noise is 15000～20000Hz, and modulating frequency is 3～30Hz, and output voltage is 0～50V.Be mainly used in needle anaesthesia and analgesia therapy etc., but in treatment, easily acupuncture needle caused electrochemical reaction, cause unexpected.
5, sound wave electric needle instrument, it is the acoustic-electric pin, it is the multiple sound source that audio wave generator is produced, as sound waves such as music, drama, song, broadcasting input electric acupuncture apparatus, output links to each other with the acupuncture needle that thrusts the acupuncture point by lead, stimulate thereby produce a kind of complex sound electric wave intricate, uneven, transition at random, thus be difficult for causing adaptability of human body, thus its effect is unattenuated when treating for a long time.Do not disturb owing to there is stronger first-harmonic, stimulate more comfortablely, the patient easily accepts, and acoustoelectric current is better than general impulse wave analgesic effect.
6, pulsed electric acupuncture apparatus is the widest a kind of electric acupuncture apparatus of present domestic and international application.It adopts intermittent oscillation is pulse generator, by the time constant of variable resistance change circuit, control impuls frequency.Be wound with the mutual isolated output winding of many groups on oscillation transformer, the output of winding is exported after the potentiometer dividing potential drop.By the defeated square wave of multivibrator, can obtain dilatational wave and discontinuous wave and pulse wave.But the frequency of these two kinds of waveforms is nonadjustable, and the fluctuating signal that square wave produces can be modulated its amplitude, and ripple and sawtooth waveforms isopulse wave mode can obtain to rise and fall.
In the Chinese medicine acupuncture treatment, acusector and hand-manoeuvring are two kinds of stimulations of different nature, acusector be rely on impressed current (voltage) be used for excited acupuncture point tissue, easily produce effect fatigue (the nervus centripetalis granting stably decays), hand-manoeuvring then is to insert the twisted purpose that waits mechanical action to reach the stimulating acupoint tissue by carrying.Therefore acusector is different with the afferent nerve fiber classification with the pin sense of hand-manoeuvring, and the former mainly imports maincenter into through the crude fibre based on the II class based on fiber crops, and the latter is expanded based on acid and felt, and main warp imports maincenter into based on the fine fibre of III class.Experimental results show that, hand-manoeuvring is good than acusector all improving skin temperature, analgesia needle anaesthesia, adjusting the stomach electricity, promote lymphocyte transformation, suppress the discharge of epilepsy sample, reduce the cortex Ach and the K+ activity that raise under the epilepsy state, improve the aspects such as Na+ activity that reduce under the epilepsy state, acusector to promote the reticuloendothelial system phagocytic function with to the polypeptide relevant with pro-opiocortin influence the aspect then than hand-manoeuvring for well.
Therefore in recent years, Chinese medicine acupuncture circle is all generally being studied the clinical effectiveness that how to improve acusector both at home and abroad, in other words be exactly that research and development can be saved manpower, replace the people do the long period continue handle the needle, embody electrical acupuncture method advantage and effect, can absorb the hand-manoeuvring effect again, control the novel Chinese medicine acupuncture method and the electric acupuncture apparatus of quantity of stimulus objectively.This has become the latest development trend of present Chinese medicine acupuncture treatment and healthcare field.
Summary of the invention
The invention provides a kind of biological information electrical pulse sequence that is used for acupuncture instrument, its objective is that the different maneuvers of inquiring into Chinese medicine acupuncture stimulate the nervus centripetalis information encoding reaction that causes, design and develop and accurately to express the biological information electrical pulse sequence that imports information decoding with the quantized various acupuncture manipulations of acupuncture into, utilize bio information feedback therapy principle that the Chinese medicine acupuncture maneuver is combined with acupuncture instrument, thereby improve the clinical efficacy of acupuncture instrument.
For achieving the above object, first kind of technical scheme that the present invention adopts is: a kind of biological information electrical pulse sequence that is used for acupuncture instrument, this electrical pulse sequence is one group of sequence of voltage pulses with chaotic characteristic, and its attractor has specificity, and the Lyapunov index is 1.7691 ± 0.0007.This programme biological information electrical pulse sequence is by Chinese medicine acupuncture even reinforcing-reducing method manipulation of acupuncture stimulating organism body acupuncture point, one group that causes on the wide power type neuron of this organism spinal cord imports the information encoding reaction into, and this imports the information encoding reaction into is one group of spike potential pulse train with chaotic motion characteristic.
For achieving the above object, second kind of technical scheme that the present invention adopts is: a kind of biological information electrical pulse sequence that is used for acupuncture instrument, this electrical pulse sequence is one group of sequence of voltage pulses with chaotic characteristic, and its attractor has specificity, and the Lyapunov index is 1.7333 ± 0.0138.This programme biological information electrical pulse sequence is by Chinese medicine acupuncture re-enforcing and reducing by twis ting and twirling of the needle manipulation of acupuncture stimulating organism body acupuncture point, one group that causes on the wide power type neuron of this organism spinal cord imports the information encoding reaction into, and this imports the information encoding reaction into is one group of spike potential pulse train with chaotic motion characteristic.
For achieving the above object, the third technical scheme that the present invention adopts is: a kind of biological information electrical pulse sequence that is used for acupuncture instrument, this electrical pulse sequence is one group of sequence of voltage pulses with chaotic characteristic, and its attractor has specificity, and the Lyapunov index is 1.7676 ± 0.0007.This programme biological information electrical pulse sequence is by the reinforcing and reducing by lifting and thrusting manipulation of acupuncture stimulating organism of Chinese medicine acupuncture body acupuncture point, one group that causes on the wide power type neuron of this organism spinal cord imports the information encoding reaction into, and this imports the information encoding reaction into is one group of spike potential pulse train with chaotic motion characteristic.
For achieving the above object, the 4th kind of technical scheme that the present invention adopts is: a kind of biological information electrical pulse sequence that is used for acupuncture instrument, this electrical pulse sequence is one group of sequence of voltage pulses with chaotic characteristic, and its attractor has specificity, and the Lyapunov index is 1.7635 ± 0.0034.This programme biological information electrical pulse sequence is by Chinese medicine acupuncture slow-rapid reinforcing-reducing method manipulation of acupuncture stimulating organism body acupuncture point, one group that causes on the wide power type neuron of this organism spinal cord imports the information encoding reaction into, and this imports the information encoding reaction into is one group of spike potential pulse train with chaotic motion characteristic.
For achieving the above object, the 5th kind of technical scheme that the present invention adopts is: a kind of biological information electrical pulse sequence that is used for acupuncture instrument, this electrical pulse sequence is one group of sequence of voltage pulses with chaotic characteristic, and its attractor has specificity, and the Lyapunov index is 1.5934 ± 0.1261.This programme biological information electrical pulse sequence is by Chinese medicine acupuncture blue dragon wagging tail manipulation of acupuncture stimulating organism body acupuncture point, one group that causes on the wide power type neuron of this organism spinal cord imports the information encoding reaction into, and this imports the information encoding reaction into is one group of spike potential pulse train with chaotic motion characteristic.
For achieving the above object, the 6th kind of technical scheme that the present invention adopts is: a kind of biological information electrical pulse sequence that is used for acupuncture instrument, this electrical pulse sequence is one group of sequence of voltage pulses with chaotic characteristic, and its attractor is unusual, and the Lyapunov index is 1.7536 ± 0.0065.This programme bio information spike potential pulse train is by Chinese medicine acupuncture dark tortoise seeking hole manipulation of acupuncture stimulating organism body acupuncture point, one group that causes on the wide power type neuron of this organism spinal cord imports the information encoding reaction into, and this imports the information encoding reaction into is one group of spike potential pulse train with chaotic motion characteristic.
The related content of technique scheme is explained as follows:
1, the principle of the invention
Bio information spike potential pulse train of the present invention is by the even reinforcing-reducing method of Chinese medicine acupuncture, re-enforcing and reducing by twis ting and twirling of the needle, reinforcing and reducing by lifting and thrusting, slow-rapid reinforcing-reducing method, blue dragon wagging tail and 6 kinds of manipulations of acupuncture of dark tortoise seeking hole stimulating organism body acupuncture point respectively, one group that causes on the wide power type neuron of this organism spinal cord imports the information encoding reaction into, this information encoding reaction that imports into is respectively one group of spike potential pulse train with chaotic motion characteristic, and it presses seasonal effect in time series chaos degree can come quantitative description with the Lyapunov index.The bio information that the various acupuncture manipulations of acupuncture cause can accurately be expressed and quantize to this spike potential pulse train, according to bio information feedback therapy principle this spike potential pulse train that contains bio information is applied to acupuncture instrument, can improves the clinical efficacy of acupuncture instrument.
2, about chaos
In non-chaos system, adjacent orbit is astringent or disperses to be slower than exponential speed, and in chaos system, adjacent orbit but is that index is dispersed.Lyapunov index (Lyapunovexponent) is exactly to be used for weighing the rate of convergence of track and to disperse speed.For being higher than unidimensional system, can calculate one group of Lyapunov index, be called Lyapunov exponential spectrum (Lyapunovexponent spectrum), wherein each index is corresponding to track convergency factor or diverging rate on certain specific direction.The exponential number of Lyapunov equals the dimension of phase space generally speaking.Chaos system in its Lyapunov exponential spectrum, have one or more on the occasion of.The exponential calculating of Lyapunov is carried out in phase space, so will calculate time series, will adopt the way of time-delay coordinate phase space reconfiguration.A successive signal uniformly-spaced to sample, is produced the time series of M dimension, and this time arrow forms the track of oneself in M dimension phase space, Here it is phase space reconfiguration.So just can be in the phase space of reconstruct calculating Lyapunov index.The Lyapunov index has been described the sensitivity of chaos system to initial value.
3, gather the neural activity coded signal that the manipulation of acupuncture causes
Utilize even reinforcing-reducing method, re-enforcing and reducing by twis ting and twirling of the needle, reinforcing and reducing by lifting and thrusting, slow-rapid reinforcing-reducing method, blue dragon wagging tail and 6 kinds of traditional Chinese medical science of dark tortoise seeking hole maneuver acupuncture tsu san li commonly used, collect the wide power neuron of cornu dorsale medullae spinalis spike potential signal time sequence respectively.
4, the neural activity coded signal that the manipulation of acupuncture that collects is caused carries out nonlinear dynamic analysis
At first carried out phase space reconfiguration, at definite reconstruction parameter: time delay T and when embedding dimension m, adopted the mutual information function to determine time-delay T; Determine to embed dimension m with the method that the Cao method combines, obtain the reconstruct attractor of every kind of maneuver.The attractor of various maneuver correspondences all is unusual, illustrates that qualitatively these signals are chaos time sequences.Utilized the exponential method of Lyapunov that is particularly suitable for calculating biosystem to portray these seasonal effect in time series chaos degree quantitatively simultaneously.
(1), to the theory of time series analysis
1., phase space reconfiguration
Employing is present most popular method by the time-delay coordinate method phase space reconstruction that Takens and Packard put forward.If the time variable sequence that obtains from real system is x (t
i), i=1 ..., N utilizes the time-delay coordinate method, can construct the state vector of a multiple embedded space
X
n＝x(n)，x(n+T)，x(n+2T)，…，x(n+(m-1)T) (1)
N=1 wherein, 2 ..., N-(m-1) T, T are called delay time (delay time), and m is called and embeds dimension (Embedding dimension).
Two very important parameters are arranged in the phase space reconfiguration process: time delay T, embed dimension m.This paper determines time-delay T with the mutual information function, determines to embed dimension m with the Cao method.
At first determine T time delay.Time-delay T is a positive integer, and the actual time delay time is the product of sampling time interval Δ t and T.If T is too little for delay time, will cause state vector very approaching, each state vector is carried a large amount of redundancies.When T → 0, all state vectors all can not be differentiated under noise conditions, cause the reconstruct attractor to be squeezed near the leading diagonal of phase space.On the contrary, if delay time T is too big, it doesn't matter basically will to cause the m dimension coordinate, even make simple figure seem also very complicated.Select the task of delay time will avoid these two kinds exactly extremely, make the time-delay coordinate independent to greatest extent, kinetic property is maintained simultaneously.Utilizing more at present is the pairing time of first local minimum of mutual information function to be defined as delay time T.Because the mutual information function is two related immediately tolerance of the generality between variable immediately, therefore utilizes the mutual information function to determine that delay time is a kind of reasonable method.
Determine the best dimension that embeds then.According to the Takens theorem, embedding dimension m should satisfy: m 〉=2d+1, d are the attractor fractal dimensions.It is too little to embed dimension m, and the reconstruct attractor is disassemble fully; But m is too big, and invariants such as Practical Calculation Lyapunov index are brought a large amount of unnecessary calculating, and has increased the effect of the pollution of noises such as round-off error and apparatus measures error.Adopt the Cao method to determine the best dimension that embeds, it is with range estimation scalar E
1(relevant dimension) determines the best dimension that embeds along with embedding the variation tendency that dimension increases.Work as E
1Pairing value is exactly the best dimension that embeds when arriving saturation point.Its advantage is: a) do not need many data points, b) can very clearly distinguish noise and chaotic signal, c) sequence with higher-dimension attractor is stood good, d) the computational efficiency height.
2., Lyapunov Index for Calculation
On the basis of phase space reconstruction, need further to analyze the temporal-spatial evolution characteristic of dynamical system.The Lyapunov index is an important motivity mathematic(al) parameter of describing the nonlinear system dynamic characteristic, and its represents to close in phase space, and track is dispersed or astringent average index rate.
Consider the one dimension mapping
x
n+1＝f(x
n) (2)
If its initial value x
0Deviation be δ x
0, then through obtaining after n the iteration
λ is called the Lyapunov index.If λ is minus, represent that then the track of phase space shrinks, can not produce chaos, zero exponent is represented to be lower than moving of index speed along track, and positive index, then the Exponential growth in time of the distance between the adjacent track, show the sensitive dependence to initial value, system is a chaos.Even so the exponential size of Lyapunov is ignorant, the type of exponent sign also can provide the qualitative situation of dynamical system.
For n dimension mapping, can adopt uses the same method obtains n the different Lyapunov index of its correspondence, but maximum Lyapunov exponent generally is most important, utilizes it to judge the chaos state of system and the chaos characteristic of extraction system.In order accurately to estimate the maximum Lyapunov exponent of the cornu dorsale medullae spinalis signal of telecommunication, the method that adopts A.Wolf to propose:
To time series x (t), utilize the time-delay coordinate method that phase space is reconstructed.With initial point x
0Be basic point, at point set { x
iNearest-neighbor point of middle search, constitute an initial vector, remember that its length is L (t
0), make it in a reasonable time, develop to time t along track
1, initial length develops to L ' (t
1), use λ
1The Exponential growth rate of representing vector length in this time period, T
0Express time length has
L’(t
1)＝L(t
0)e
λ 1T
0 (4)
When search, desired data point should satisfy two criterions: 1. each evolution vector should have smaller length, 2. develops vectorial and be replaced vector to keep little angle.If meet can not finding of above-mentioned condition, keep presently used vector temporarily, said process is performed until point set { x
iTerminal point, the meansigma methods of getting the Exponential growth rate is as the exponential estimated value of the Lyapunov of maximum, promptly
In the formula, N
kThe total step number that expression is developed, k represents constant.
Constantly repeat top computational process, stable up to the estimated value maintenance of λ, the result that obtain this moment is the maximum Lyapunov exponent of being asked.
(2), Data Processing in Experiment
The data that 6 kinds of maneuvers are obtained are analyzed respectively, the sequence number strong point that we select for use is 80000, go through 20s, wherein, the even reinforcing-reducing method maneuver as shown in Figure 1, the re-enforcing and reducing by twis ting and twirling of the needle maneuver is as shown in Figure 4, reinforcing and reducing by lifting and thrusting maneuver as shown in Figure 7, the slow-rapid reinforcing-reducing method maneuver as shown in figure 10, the blue dragon wagging tail maneuver as shown in figure 13, the dark tortoise seeking hole maneuver is as shown in figure 16.
At first carry out the calculating of time delay and embedding dimension, two kinds of parameters can be painted to such an extent that phase space reconfiguration attracts subgraph thus, wherein, the even reinforcing-reducing method maneuver as shown in Figure 2, the re-enforcing and reducing by twis ting and twirling of the needle maneuver as shown in Figure 5, reinforcing and reducing by lifting and thrusting maneuver as shown in Figure 8, the slow-rapid reinforcing-reducing method maneuver is as shown in figure 11, the blue dragon wagging tail maneuver as shown in figure 14, the dark tortoise seeking hole maneuver is as shown in figure 17.From these six figure as can be seen, the attractor of the corresponding waveforms of 6 kinds of maneuvers all is unusual, and different maneuver shows different shapes, can determine tentatively that these signals are chaos.
Utilize maximum Lyapunov exponent (L) to come the chaos degree of these 6 kinds of sequences of quantitative analysis at last, wherein, the even reinforcing-reducing method maneuver as shown in Figure 3, the re-enforcing and reducing by twis ting and twirling of the needle maneuver as shown in Figure 6, reinforcing and reducing by lifting and thrusting maneuver as shown in Figure 9, the slow-rapid reinforcing-reducing method maneuver as shown in figure 12, the blue dragon wagging tail maneuver as shown in figure 15, the dark tortoise seeking hole maneuver is as shown in figure 18.
The attractor structure of six kinds of maneuvers seems identical, but its Lyapunov index has difference, the pairing Lyapunov index of the signal of six kinds of maneuvers is respectively: 1.7691,1.7333,1.7676,1.7635,1.5934,1.7536 the exponential difference of Lyapunov has reflected the difference that signal develops in time.Therefore can think: the neural activity information coding that every kind of manipulation of acupuncture causes all has its distinctive attraction subring, the Lyapunov index of its maneuver feature that all responds on this basis.
Because the technique scheme utilization, the present invention compared with prior art has following advantage and effect:
1, the present invention is justifiable will be the once great revolution of the clinical and scientific research field of traditional Chinese medicine acupuncture, promote the collaborative development of the science of acupuncture and moxibustion and bioinformatics, and then promote the standardized process of Chinese medicine acupuncture, carry forward this nonmaterial culture.
2, acupuncture is a kind of irritation therapy of body surface, and the acupuncture information spinner will be transmitted to the central nervous system by afferent nervous system.It is to bring into play integration and regulation and control to the body functional activity with one group of group in the presence of coding form in mesencephalic centre of time and spatial sequence combination nerve information.The information of importing into the coding of understanding acupuncture not only can quantize to understand acapuncture action and mechanism, also will promote the understanding to the processing procedure of nerve information.The research of acupuncture and the conduction and the processing of nerve information coding form are combined research, and this original research will promote the collaborative development of two science.
3, be cloned under the manipulation of acupuncture that the present invention can differ from one another the famous expert and extensively receive on the various wide power type neurons of spinal cord that import information into, formed the decode procedure of various maneuvers the special stimulation of nervus centripetalis.Bio information spike potential of the present invention pulse is not an impressed current, but the nerve of organism self imports the information coded pulse into, meet the biofeedback therapy principle, bio information group coding is not the single pulse that simple electric pulse signal generator sends, organize sensor to be difficult for adapting to, thereby keep successive, changeable stimulation state, thereby further improved the clinical efficacy of acupuncture instrument.Simple constant impulse stimulation produces fast-the chronic adaptation phenomenon human feeling's device easily, and under stimulus intensity and the constant situation of frequency, the reaction of importing into of sensor reduces very fast adaptation and stops gradually.
4,6 kinds of manipulations of acupuncture commonly used of the present invention stimulate the group's coding that produces to differ from one another, and do not see that in the whole process of handling the needle electroacupuncture stimulation equally adapts to (the nervus centripetalis granting stably decays).Have been noted that in laboratory observation different skill of handling needles acusectors have nothing in common with each other to the electricity irritation of different body surface pain and the inhibitory action of chronic inflammation pain and Encelialgia.Thereby the clinician can select the different skill of handling needles to adapt to the acupuncture individualized treatment according to the state of an illness.
Description of drawings
Accompanying drawing 1 collects the signal of telecommunication time series of going through 20s for adopting the even reinforcing-reducing method manipulation of acupuncture from cornu dorsale medullae spinalis, wherein, and the abscissa express time, second; Vertical coordinate is represented neuron spike potential amplitude, and unit is a microvolt.
Accompanying drawing 2 is that the phase space reconfiguration of even reinforcing-reducing method maneuver correspondence attracts subgraph, and wherein, abscissa is represented a bit of action potential amplitude-calculating; Vertical coordinate is represented another point of action potential amplitude-calculating.
Accompanying drawing 3 is the Lyapunov index collection of illustrative plates of even reinforcing-reducing method maneuver correspondence, and wherein, the calculating of abscissa express time is counted; Vertical coordinate is represented dimensionless, the reduced value of the coding of neuron reaction.
Accompanying drawing 4 collects the signal of telecommunication time series of going through 20s for adopting the re-enforcing and reducing by twis ting and twirling of the needle manipulation of acupuncture from cornu dorsale medullae spinalis, wherein, and the abscissa express time, second; Vertical coordinate is represented neuron spike potential amplitude, and unit is a microvolt.
Accompanying drawing 5 attracts subgraph for the phase space reconfiguration of re-enforcing and reducing by twis ting and twirling of the needle maneuver correspondence, and wherein, abscissa is represented a bit of action potential amplitude-calculating; Vertical coordinate is represented another point of action potential amplitude-calculating.
Accompanying drawing 6 is the Lyapunov index collection of illustrative plates of re-enforcing and reducing by twis ting and twirling of the needle maneuver correspondence, and wherein, the calculating of abscissa express time is counted; Vertical coordinate is represented dimensionless, the reduced value of the coding of neuron reaction.
Accompanying drawing 7 collects the signal of telecommunication time series of going through 20s for adopting the reinforcing and reducing by lifting and thrusting manipulation of acupuncture from cornu dorsale medullae spinalis, wherein, and the abscissa express time, second; Vertical coordinate is represented neuron spike potential amplitude, and unit is a microvolt.
Accompanying drawing 8 is that the phase space reconfiguration of reinforcing and reducing by lifting and thrusting maneuver correspondence attracts subgraph, and wherein, abscissa is represented a bit of action potential amplitude-calculating; Vertical coordinate is represented another point of action potential amplitude-calculating.
Accompanying drawing 9 is the Lyapunov index collection of illustrative plates of reinforcing and reducing by lifting and thrusting maneuver correspondence, and wherein, the calculating of abscissa express time is counted; Vertical coordinate is represented dimensionless, the reduced value of the coding of neuron reaction.
Accompanying drawing 10 collects the signal of telecommunication time series of going through 20s for adopting the slow-rapid reinforcing-reducing method manipulation of acupuncture from cornu dorsale medullae spinalis, wherein, and the abscissa express time, second; Vertical coordinate is represented neuron spike potential amplitude, and unit is a microvolt.
Accompanying drawing 11 is that the phase space reconfiguration of slow-rapid reinforcing-reducing method maneuver correspondence attracts subgraph, and wherein, abscissa is represented a bit of action potential amplitude-calculating; Vertical coordinate is represented another point of action potential amplitude-calculating.
Accompanying drawing 12 is the Lyapunov index collection of illustrative plates of slow-rapid reinforcing-reducing method maneuver correspondence, and wherein, the calculating of abscissa express time is counted; Vertical coordinate is represented dimensionless, the reduced value of the coding of neuron reaction.
Accompanying drawing 13 collects the signal of telecommunication time series of going through 20s for adopting the blue dragon wagging tail manipulation of acupuncture from cornu dorsale medullae spinalis, wherein, and the abscissa express time, second; Vertical coordinate is represented neuron spike potential amplitude, and unit is a microvolt.
Accompanying drawing 14 is that the phase space reconfiguration of blue dragon wagging tail maneuver correspondence attracts subgraph, and wherein, abscissa is represented a bit of action potential amplitude-calculating; Vertical coordinate is represented another point of action potential amplitude-calculating.
Accompanying drawing 15 is the Lyapunov index collection of illustrative plates of blue dragon wagging tail maneuver correspondence, and wherein, the calculating of abscissa express time is counted; Vertical coordinate is represented dimensionless, the reduced value of the coding of neuron reaction.
Accompanying drawing 16 collects the signal of telecommunication time series of going through 20s for adopting the dark tortoise seeking hole manipulation of acupuncture from cornu dorsale medullae spinalis, wherein, and the abscissa express time, second; Vertical coordinate is represented neuron spike potential amplitude, and unit is a microvolt.
Accompanying drawing 17 is that the phase space reconfiguration of dark tortoise seeking hole maneuver correspondence attracts subgraph, and wherein, abscissa is represented a bit of action potential amplitude-calculating; Vertical coordinate is represented another point of action potential amplitude-calculating.
Accompanying drawing 18 is the Lyapunov index collection of illustrative plates of dark tortoise seeking hole maneuver correspondence, and wherein, the calculating of abscissa express time is counted; Vertical coordinate is represented dimensionless, the reduced value of the coding of neuron reaction.
The specific embodiment
Below in conjunction with drawings and Examples the present invention is further described:
Embodiment one: the bio information spike potential pulse train of even reinforcing-reducing method manipulation of acupuncture correspondence
A kind of bio information spike potential pulse train that is used for acupuncture instrument, this electrical pulse sequence is by Chinese medicine acupuncture even reinforcing-reducing method manipulation of acupuncture stimulating organism body acupuncture point, one group that causes on the wide power type neuron of this organism spinal cord imports the information encoding reaction into, this imports the information encoding reaction into is one group of sequence of voltage pulses with chaotic characteristic, its attractor has specificity, and the Lyapunov index is 1.7691.
Fig. 1 collects the signal of telecommunication time series of going through 20s for the embodiment even reinforcing-reducing method manipulation of acupuncture from cornu dorsale medullae spinalis.Fig. 2 is that the phase space reconfiguration of embodiment even reinforcing-reducing method maneuver correspondence attracts subgraph.Fig. 3 is the Lyapunov index collection of illustrative plates of embodiment even reinforcing-reducing method maneuver correspondence.
Embodiment two: the bio information spike potential pulse train of re-enforcing and reducing by twis ting and twirling of the needle manipulation of acupuncture correspondence
A kind of bio information spike potential pulse train that is used for acupuncture instrument, this electrical pulse sequence is by Chinese medicine acupuncture re-enforcing and reducing by twis ting and twirling of the needle manipulation of acupuncture stimulating organism body acupuncture point, one group that causes on the wide power type neuron of this organism spinal cord imports the information encoding reaction into, this imports the information encoding reaction into is one group of sequence of voltage pulses with chaotic characteristic, its attractor has specificity, and the Lyapunov index is 1.7333.
Fig. 4 collects the signal of telecommunication time series of going through 20s for the embodiment re-enforcing and reducing by twis ting and twirling of the needle manipulation of acupuncture from cornu dorsale medullae spinalis.Fig. 5 is that the phase space reconfiguration of embodiment re-enforcing and reducing by twis ting and twirling of the needle maneuver correspondence attracts subgraph.Fig. 6 is the Lyapunov index collection of illustrative plates of embodiment re-enforcing and reducing by twis ting and twirling of the needle maneuver correspondence.
Embodiment three: the bio information spike potential pulse train of reinforcing and reducing by lifting and thrusting manipulation of acupuncture correspondence
A kind of bio information spike potential pulse train that is used for acupuncture instrument, this electrical pulse sequence is by the reinforcing and reducing by lifting and thrusting manipulation of acupuncture stimulating organism of Chinese medicine acupuncture body acupuncture point, one group that causes on the wide power type neuron of this organism spinal cord imports the information encoding reaction into, this imports the information encoding reaction into is one group of sequence of voltage pulses with chaotic characteristic, its attractor has specificity, and the Lyapunov index is 1.7676.
Fig. 7 collects the signal of telecommunication time series of going through 20s for the reinforcing and reducing by lifting and thrusting manipulation of acupuncture of embodiment from cornu dorsale medullae spinalis.Fig. 8 is that the phase space reconfiguration of the reinforcing and reducing by lifting and thrusting maneuver correspondence of embodiment attracts subgraph.Fig. 9 is the Lyapunov index collection of illustrative plates of the reinforcing and reducing by lifting and thrusting maneuver correspondence of embodiment.
Embodiment four: the bio information spike potential pulse train of slow-rapid reinforcing-reducing method manipulation of acupuncture correspondence
A kind of bio information spike potential pulse train that is used for acupuncture instrument, this electrical pulse sequence is by Chinese medicine acupuncture slow-rapid reinforcing-reducing method manipulation of acupuncture stimulating organism body acupuncture point, one group that causes on the wide power type neuron of this organism spinal cord imports the information encoding reaction into, this imports the information encoding reaction into is one group of sequence of voltage pulses with chaotic characteristic, its attractor has specificity, and the Lyapunov index is 1.7635.
Figure 10 collects the signal of telecommunication time series of going through 20s for the embodiment slow-rapid reinforcing-reducing method manipulation of acupuncture from cornu dorsale medullae spinalis.Figure 11 is that the phase space reconfiguration of embodiment slow-rapid reinforcing-reducing method maneuver correspondence attracts subgraph.Figure 12 is the Lyapunov index collection of illustrative plates of embodiment slow-rapid reinforcing-reducing method maneuver correspondence.
Embodiment five: the bio information spike potential pulse train of blue dragon wagging tail manipulation of acupuncture correspondence
A kind of bio information spike potential pulse train that is used for acupuncture instrument, this electrical pulse sequence is by Chinese medicine acupuncture blue dragon wagging tail manipulation of acupuncture stimulating organism body acupuncture point, one group that causes on the wide power type neuron of this organism spinal cord imports the information encoding reaction into, this imports the information encoding reaction into is one group of sequence of voltage pulses with chaotic characteristic, its attractor has specificity, and the Lyapunov index is 1.5934.
Figure 13 collects the signal of telecommunication time series of going through 20s for the embodiment blue dragon wagging tail manipulation of acupuncture from cornu dorsale medullae spinalis.Figure 14 is that the phase space reconfiguration of embodiment blue dragon wagging tail maneuver correspondence attracts subgraph.Figure 15 is the Lyapunov index collection of illustrative plates of embodiment blue dragon wagging tail maneuver correspondence.
Embodiment six: the bio information spike potential pulse train of dark tortoise seeking hole manipulation of acupuncture correspondence
A kind of bio information spike potential pulse train that is used for acupuncture instrument, this electrical pulse sequence is by Chinese medicine acupuncture dark tortoise seeking hole manipulation of acupuncture stimulating organism body acupuncture point, one group that causes on the wide power type neuron of this organism spinal cord imports the information encoding reaction into, this imports the information encoding reaction into is one group of sequence of voltage pulses with chaotic characteristic, its attractor has specificity, and the Lyapunov index is 1.7536.
Figure 16 collects the signal of telecommunication time series of going through 20s for the embodiment dark tortoise seeking hole manipulation of acupuncture from cornu dorsale medullae spinalis.Figure 17 is that the phase space reconfiguration of embodiment dark tortoise seeking hole maneuver correspondence attracts subgraph.Figure 18 is the Lyapunov index collection of illustrative plates of embodiment dark tortoise seeking hole maneuver correspondence.
The foregoing description only is explanation technical conceive of the present invention and characteristics, and its purpose is to allow the personage who is familiar with this technology can understand content of the present invention and enforcement according to this, can not limit protection scope of the present invention with this.All equivalences that spirit is done according to the present invention change or modify, and all should be encompassed within protection scope of the present invention.
Claims (6)
1. biological information electrical pulse sequence that is used for acupuncture instrument, it is characterized in that: this electrical pulse sequence is one group of sequence of voltage pulses with chaotic characteristic, and its attractor has specificity, the Lyapunov index is 1.7691 ± 0.0007.
2. biological information electrical pulse sequence that is used for acupuncture instrument, it is characterized in that: this electrical pulse sequence is one group of sequence of voltage pulses with chaotic characteristic, and its attractor has specificity, the Lyapunov index is 1.7333 ± 0.0138.
3. biological information electrical pulse sequence that is used for acupuncture instrument, it is characterized in that: this electrical pulse sequence is one group of sequence of voltage pulses with chaotic characteristic, and its attractor has specificity, the Lyapunov index is 1.7676 ± 0.0007.
4. biological information electrical pulse sequence that is used for acupuncture instrument, it is characterized in that: this electrical pulse sequence is one group of sequence of voltage pulses with chaotic characteristic, and its attractor has specificity, the Lyapunov index is 1.7635 ± 0.0034.
5. biological information electrical pulse sequence that is used for acupuncture instrument, it is characterized in that: this electrical pulse sequence is one group of sequence of voltage pulses with chaotic characteristic, and its attractor has specificity, the Lyapunov index is 1.5934 ± 0.1261.
6. biological information electrical pulse sequence that is used for acupuncture instrument, it is characterized in that: this electrical pulse sequence is one group of sequence of voltage pulses with chaotic characteristic, and its attractor has specificity, the Lyapunov index is 1.7536 ± 0.0065.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103300854A (en) * | 2012-03-16 | 2013-09-18 | 上海中医药大学 | Human acupuncture point chaotic characteristic measuring instrument based on virtual instrument and measuring method thereof |
| CN103391071A (en) * | 2013-07-18 | 2013-11-13 | 苏州好博医疗器械有限公司 | Pulse generator for swallowing dysfunction treatment |
-
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103300854A (en) * | 2012-03-16 | 2013-09-18 | 上海中医药大学 | Human acupuncture point chaotic characteristic measuring instrument based on virtual instrument and measuring method thereof |
| CN103391071A (en) * | 2013-07-18 | 2013-11-13 | 苏州好博医疗器械有限公司 | Pulse generator for swallowing dysfunction treatment |
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