CN201701309U - Pain stimulating device - Google Patents

Pain stimulating device Download PDF

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Publication number
CN201701309U
CN201701309U CN2010202256378U CN201020225637U CN201701309U CN 201701309 U CN201701309 U CN 201701309U CN 2010202256378 U CN2010202256378 U CN 2010202256378U CN 201020225637 U CN201020225637 U CN 201020225637U CN 201701309 U CN201701309 U CN 201701309U
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China
Prior art keywords
pain
terminal
tested object
feedback
physical signs
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Expired - Lifetime
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CN2010202256378U
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Chinese (zh)
Inventor
秋云海
王立平
李光林
徐昊
吴心音
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Shenzhen Institute of Advanced Technology of CAS
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Shenzhen Institute of Advanced Technology of CAS
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Abstract

The utility model relates to a pain stimulating device comprising a micro-injection pump, an objective physiological index acquiring terminal, a pain estimating terminal, a feedback unit and a controller, wherein the micro-injection pump is used for injecting high-permeability physiological saline to a measured object to stimulate the measured object to generate a continuous pain; the objective physiological index acquiring terminal is used for acquiring the pain objective physiological index of the measured object; the pain estimating terminal is used for analyzing and estimating the pain according to the pain objective physiological index and providing a pain estimation value; the feedback unit is used for carrying out feedback to the pain estimation value to provide a feedback value; and the controller is used for controlling the injection speed of the micro-injection pump according to the feedback value. The pain stimulating device uses the micro-injection pump for injecting the high-permeability physiological saline to the measured object to stimulate the measured object to generate the pain, the objective physiological index of the measured object is acquired in real time for analyzing and estimating the pain, the pain estimate value is accurately provided for feedback, the injection speed is regulated, and finally the constant and continuous pain of the expected degree is obtained; and therefore, the pain stimulating device is greatly convenient for people to research and simulate the pain, improves the researching accuracy of the pain and takes the effect of great promotion on treating the pain.

Description

The pain stimulation device
[technical field]
This utility model relates to a kind of medical apparatus and instruments, relates in particular to a kind of pain stimulation device.
[background technology]
Pain is as one of the most general clinical symptoms, and is little of to pain object (human body or animal) quality of life, brought a lot of negative effects to the health and the surroundings thereof of pain object greatly.
Treatment pain must be studied the mechanism of pain generation and the impression and the variation of different pain degree pain objects.At present, research pain mostly by with human body or animal as tested object, stimulate tested object to produce of short duration pain, observe the change of tested object behavior, language and manner and judge pain degree, obtain the pain in various degree that needs pain is studied.
But pain is kind of offending impression and emotional experience, with other coenesthesia (auditions, vision) difference, be subjected to psychology and society factors to a great extent, by tested object behavior, the change of language and manner judges that pain degree is very inaccurate, especially for animal, can't understand its language, also can't accurately understand its behavior, simultaneously, different doctors are for tested object behavior, language has different judgements with manner, subjectivity is strong, thereby can not accurately obtain the lasting constant pain of expected degree, brings very big inconvenience for research pain.
[utility model content]
Based on this, be necessary the pain stimulation device that provides a kind of lasting constant pain that obtains expected degree to study.
A kind of pain stimulation device, comprise to tested target injection hypertonic saline stimulate tested object to produce the micro-injection pump of constant pain, the objective physical signs of obtaining the objective physical signs of tested object pain is in real time obtained terminal, according to the objective physical signs of pain pain is analyzed and is assessed and provide the pain assessed value pain assessment terminal, feed back the feedback unit that provides value of feedback and according to the controller of value of feedback control micro-injection pump injection speed according to the pain assessed value.
Preferably, described objective physical signs is obtained the heart rate that terminal comprises that the multichannel brain electric wave that obtains tested object brain wave obtains terminal, the skin conductivity rate of obtaining tested subject's skin conductivity is obtained terminal and obtain tested object heart rate and is obtained terminal.
Preferably, described multichannel brain electric wave obtains terminal and comprises brain wave monitoring electrode and reference electrode.
Preferably, described skin conductivity rate is obtained terminal and is comprised silver-colored solid reference electrode or silver chloride solid reference electrode.
Preferably, described heart rate obtains terminal and comprises the heart rate electrode.
Preferably, also comprise the display terminal that the objective physical signs of tested object and pain assessed value are shown, described display terminal links to each other with described pain assessment terminal.
Above-mentioned pain stimulation device, use micro-injection pump to stimulate tested object to produce pain to tested target injection hypertonic saline, obtaining the objective physical signs of tested object in real time analyzes and assesses pain, accurately the objective pain assessed value that provides is fed back the micro-injection pump injection speed, regulate the injection speed of hypertonic saline, obtain the constant and lasting pain of expected degree, research and simulation have greatly been made things convenient for to pain, improved the accuracy of pain research, played very big impetus for treatment pain.Especially for the research of animal behavior, overcome disturbance of understanding, greatly improved, great impetus has been played in research and the cognition of animal animal pain behavioral study accuracy to its language, behavior and manner.
[description of drawings]
Fig. 1 is the structural representation of pain stimulation device.
Fig. 2 is that objective physical signs is obtained the terminal structure sketch map.
[specific embodiment]
Below in conjunction with accompanying drawing,, will make the technical solution of the utility model and other beneficial effects apparent by the specific embodiment of the present utility model is described in detail.
Fig. 1 is the structural representation of pain stimulation device.Pain stimulation device 10 comprises that micro-injection pump 100, objective physical signs are obtained terminal 200, pain is assessed terminal 300, feedback unit 400 and controller 500.
Micro-injection pump 100 is to tested object 600 (human body or animal, can be that healthy human body or animal also can make human body or the animal that suffers from pain) the injection hypertonic saline, stimulate tested object 600 to produce pain, the speed difference of injection can make tested object 600 produce and continue constant pain the pain degree difference that tested object 600 produces when keeping constant speed.The hypertonic saline injection speed is by controller 500 controls.
Objective physical signs is obtained terminal 200 and is obtained tested object 600 and the closely-related physical signs of pain (brain wave, skin conductivity rate, heart rate, respiratory frequency and amplitude, blood pressure etc.) in real time.In conjunction with Fig. 2 is that objective physical signs is obtained the terminal structure sketch map, in the optimum embodiment of this utility model, it is brain wave, skin conductivity rate and the heart rate of tested object 600 that objective physical signs is obtained the physical signs that terminal 200 obtains, and it comprises that the multichannel brain electric wave obtains terminal 210 (preferably using 128 passages), the skin conductivity rate obtains terminal 220 and heart rate obtains terminal 230.
The terminal 210 of obtaining the multichannel brain electric wave adopts two external electrodes to obtain the brain wave of tested object 600, is respectively a brain wave monitoring electrode and a reference electrode.When obtaining brain wave, brain wave monitoring electrode is connected to the motor area of cerebral cortex (CZ) of tested object 600, and reference electrode is connected to the ear of tested object 600.
The skin conductivity rate is obtained terminal 220 and is adopted silver-colored solid reference electrode or silver chloride solid reference electrode to obtain the skin conductivity rate of tested object 600.When obtaining the skin conductivity rate, if tested object 600 is a human body, silver solid reference electrode or silver chloride solid reference electrode be positioned over the finger veutro of human body forefinger, if tested object 600 is animal, silver solid reference electrode or silver chloride solid reference electrode are positioned over the palmar of animal, and sample rate is 200sample/sec.
Heart rate obtains terminal 230 and adopts the heart rate measurement electrode to obtain the heart rate of tested object.When obtaining heart rate, if tested object 600 be human body, the heart rate measurement electrode is positioned over the finger veutro of human body middle finger, if tested object 600 is an animal, the heart rate measurement electrode is positioned over the palmar of animal, sample rate is 200sample/sec.
The multichannel E.E.G obtains terminal 210, skin conductivity rate and obtains terminal 220 and heart rate and obtain terminal 230 and all adopt the electrode contact to obtain the physical signs of tested object 600, tested object 600 is not caused wound, avoid tested object 600 is caused new injury and pain, influence is to the assessment of pain.
Pain assessment terminal 300 is obtained the physical signs that terminal 200 is obtained according to the objective physical signs that receives, adopt mathematical methods such as fuzzy theory, gray system and neutral net to analyze the relation of each physical signs and pain, the relation of comprehensive then each physical signs and pain provides quantitative pain assessed value, and the pain degree of tested object 600 is assessed.
Tested object 600 (healthy humans and animals) is except that individual variation, and brain wave all respectively has its characteristics, but with regard to normal adult and animal brain electric wave, its waveform, wave amplitude, frequency and position equate all to have certain characteristics.Height according to its frequency is divided into following four kinds with waveform clinically:
The β ripple: frequency is more than 13C/S, and wave amplitude is about half of δ ripple, and forehead and central area are the most obvious.
The α ripple: frequency is 8 to 13C/S, wave amplitude 25 to 75 μ V, and the most obvious with the top occipitalia, bilateral is roughly synchronous, repeats rhythm and pace of moving things ground and the δ ripple occurs and be called theta rhythm.
The Φ ripple: frequency is 4 to 7C/S, wave amplitude 20 to 40 μ V, and lateral symmetry, see more in the temporo district.
The δ ripple: frequency is below the 4C/S, and delta rhythm is mainly in the frontal region, and one and non-circumscribed δ ripple less than 20 μ V is normal, and focal δ ripple then is unusual.δ ripple and β ripple are referred to as slow wave.
Pain assessment terminal 300 receives the brain wave that the multichannel E.E.Gs obtain the tested object 600 that terminal 210 obtains, adopt multichannel brain electric node rule analytical technology, obtain the variation of tested object 600 brain wave frequencies, wave amplitude, and the variation of the brain wave rhythm and pace of moving things, and according to the above-mentioned normal brain activity electric wave statistical law that draws clinically, analyze tested object 600 brain wave frequencies, wave amplitude and the variation of the brain wave rhythm and pace of moving things and the relation of pain, zone and character to pain are differentiated, pain degree is assessed.
Pain assessment terminal 300 receives the skin conductivity rates and obtains the heart rate that tested object 600 skin conductivity rates that terminal 220 obtains and heart rate obtain the tested object 600 that terminal 230 obtains, remove high frequency spurious signal and noise, the skin conductivity rate is calculated as skin conductivity rate fluctuation number (Number of Fluctuation in SkinConductance is called for short NFSC/min), and according to the situation of change of skin conductivity rate fluctuation number, the relation of analyzing skin conductivity and pain is assessed pain degree.
Pain assessment terminal 300 is analyzed the relation of heart rate and pain according to the situation of change of heart rate, and pain degree is assessed.
The relation of pain assessment terminal 300 comprehensive a plurality of physical signs and pain to the assessment that pain degree carries out, provides a comprehensive pain assessed value, and the degree of pain is carried out comprehensive reflection.
Feedback unit 400 receives the pain assessed value that pain assessment terminals 300 provide, and provides the value of feedback with corresponding adjusting micro-injection pump 100 injection speeds of pain assessed value, and sends value of feedback to controller 500.
Controller 500 receives value of feedback, and regulate the injection speed of micro-injection pump 100 according to value of feedback, the pain degree that control produces tested object 600, make pain degree in preset range, continue to change, obtain expected degree and can keep the pain of constant degree, so that better study mechanism that pain produces and the variation that causes tested object 600.
The objective physical signs of 700 pairs of acquisitions of display terminal and the pain assessed value shown gets information about the variation of objective physical signs and pain degree, realizes visual.
Above-mentioned pain stimulation device 10, microsyringe 100 is injected hypertonic salines with certain speed to tested object 600, the constant pain that tested object 600 is produced to a certain degree, cause the effects on physiological indexes relevant with pain, objective physical signs is obtained terminal 200 and is obtained the physical signs relevant with pain, transfer to pain assessment terminal 300 pain assessment terminal 300 and analyze the relation of objective effects on physiological indexes and pain, the relieve pain mechanism and the objective effects on physiological indexes rule of different pain that produce, the relation of comprehensive then objective effects on physiological indexes and pain is carried out objective evaluation to pain, provides the pain assessed value.Feedback unit 400 receives the pain assessed value and produces value of feedback, transfers to controller 500.Controller 500 is adjusted the injection speed of micro-injection pump 100 according to value of feedback, the pain that makes tested object 600 produce another degree is studied, so, form closed feedback loop, constantly obtain the pain of different expected degrees, pain is studied, the mechanism that produces of relieve pain and the variation that causes tested object 600.
Above-mentioned pain stimulation device, use micro-injection pump to stimulate tested object to produce pain to tested target injection hypertonic saline, obtaining the objective physical signs of tested object in real time analyzes and assesses pain, accurately the objective pain assessed value that provides is fed back the micro-injection pump injection speed, regulate the injection speed of hypertonic saline, obtain the constant and lasting pain of expected degree, research and simulation have greatly been made things convenient for to pain, improved the accuracy of pain research, played very big impetus for treatment pain.Especially for the research of animal behavior, overcome disturbance of understanding, greatly improved, great impetus has been played in research and the cognition of animal animal pain behavioral study accuracy to its language, behavior and manner.
The above embodiment has only expressed embodiment of the present utility model, and it describes comparatively concrete and detailed, but can not therefore be interpreted as the restriction to this utility model claim.Should be pointed out that for the person of ordinary skill of the art under the prerequisite that does not break away from this utility model design, can also make some distortion and improvement, these all belong to protection domain of the present utility model.Therefore, the protection domain of this utility model patent should be as the criterion with claims.

Claims (6)

1. pain stimulation device is characterized in that: comprise to tested target injection hypertonic saline stimulate tested object to produce the micro-injection pump of constant pain, the objective physical signs of obtaining the objective physical signs of tested object pain is in real time obtained terminal, according to the objective physical signs of pain pain is analyzed and is assessed and provide the pain assessed value pain assessment terminal, feed back the feedback unit that provides value of feedback and according to the controller of value of feedback control micro-injection pump injection speed according to the pain assessed value.
2. pain stimulation device according to claim 1 is characterized in that: described objective physical signs is obtained the heart rate that terminal comprises that the multichannel brain electric wave that obtains tested object brain wave obtains terminal, the skin conductivity rate of obtaining tested subject's skin conductivity is obtained terminal and obtain tested object heart rate and is obtained terminal.
3. pain stimulation device according to claim 2 is characterized in that: described multichannel brain electric wave obtains terminal and comprises brain wave monitoring electrode and reference electrode.
4. pain stimulation device according to claim 2 is characterized in that: described skin conductivity rate is obtained terminal and is comprised silver-colored solid reference electrode or silver chloride solid reference electrode.
5. pain stimulation device according to claim 2 is characterized in that: described heart rate obtains terminal and comprises the heart rate electrode.
6. pain stimulation device according to claim 1 is characterized in that: also comprise the display terminal that the objective physical signs of tested object and pain assessed value are shown, described display terminal links to each other with described pain assessment terminal.
CN2010202256378U 2010-06-07 2010-06-07 Pain stimulating device Expired - Lifetime CN201701309U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107427248A (en) * 2015-02-24 2017-12-01 国立大学法人大阪大学 pain measuring device and pain measurement system

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107427248A (en) * 2015-02-24 2017-12-01 国立大学法人大阪大学 pain measuring device and pain measurement system

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