CN101133080A - 天然来源的蛋白质及由其制备的材料 - Google Patents

天然来源的蛋白质及由其制备的材料 Download PDF

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Publication number
CN101133080A
CN101133080A CNA2005800243750A CN200580024375A CN101133080A CN 101133080 A CN101133080 A CN 101133080A CN A2005800243750 A CNA2005800243750 A CN A2005800243750A CN 200580024375 A CN200580024375 A CN 200580024375A CN 101133080 A CN101133080 A CN 101133080A
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CN
China
Prior art keywords
adf
protein
silk
gly
seq
Prior art date
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Pending
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CNA2005800243750A
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English (en)
Chinese (zh)
Inventor
T·沙伊贝尔
D·许梅里希
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AMSilk GmbH
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Technical University of Munich
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Publication of CN101133080A publication Critical patent/CN101133080A/zh
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    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F4/00—Monocomponent artificial filaments or the like of proteins; Manufacture thereof
    • D01F4/02—Monocomponent artificial filaments or the like of proteins; Manufacture thereof from fibroin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06—At least partially resorbable materials
    • A61L17/08—At least partially resorbable materials of animal origin, e.g. catgut, collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06166—Sutures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/08—Muscles; Tendons; Ligaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30756—Cartilage endoprostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Insects & Arthropods (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Botany (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Textile Engineering (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Artificial Filaments (AREA)
CNA2005800243750A 2004-06-25 2005-06-23 天然来源的蛋白质及由其制备的材料 Pending CN101133080A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58322704P 2004-06-25 2004-06-25
US60/583,227 2004-06-25
EP05005395.8 2005-03-11

Publications (1)

Publication Number Publication Date
CN101133080A true CN101133080A (zh) 2008-02-27

Family

ID=34934219

Family Applications (1)

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CNA2005800243750A Pending CN101133080A (zh) 2004-06-25 2005-06-23 天然来源的蛋白质及由其制备的材料

Country Status (5)

Country Link
US (2) US8030024B2 (cg-RX-API-DMAC7.html)
EP (3) EP1609801A1 (cg-RX-API-DMAC7.html)
JP (1) JP4990763B2 (cg-RX-API-DMAC7.html)
CN (1) CN101133080A (cg-RX-API-DMAC7.html)
WO (2) WO2006002827A1 (cg-RX-API-DMAC7.html)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108290935A (zh) * 2015-08-10 2018-07-17 赛威克斯材料科学公司 用于制造合成的拖丝蜘蛛丝的组合物和方法
CN109477252A (zh) * 2016-02-11 2019-03-15 赛威克斯材料科学公司 包括合成拖丝蜘蛛丝的复合材料
CN112567083A (zh) * 2018-04-03 2021-03-26 丝芭博株式会社 高收缩人造丝心蛋白加捻纱及其制造方法、以及人造丝心蛋白加捻纱及其收缩方法
CN112680884A (zh) * 2020-12-30 2021-04-20 苏州经贸职业技术学院 一种抗菌口罩材料的制备方法
US12453688B2 (en) 2020-04-23 2025-10-28 Seevix Material Sciences Ltd. Cosmetic compositions comprising dragline spider silk
US12668828B2 (en) 2019-07-04 2026-06-30 Seevix Material Sciences Ltd. Prokaryotic expression system and methods of using the same

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EP1609801A1 (en) * 2004-06-25 2005-12-28 Technische Universität München Proteins of natural origin and materials made therefrom
DE102005043609A1 (de) * 2005-09-13 2007-03-22 Technische Universität München Verfahren und Vorrichtung zur Herstellung eines Fadens aus Seidenproteinen
RU2444527C2 (ru) 2005-12-30 2012-03-10 Спибер Текнолоджиз Аб Рекомбинантный спидроиновый белок главной ампулярной железы, способный к полимеризации, рекомбинантный слитый белок, способный к управляемой полимеризации, полимер спидроинового белка главной ампулярной железы, композиция для управляемой полимеризации, рекомбинантная молекула нуклеиновой кислоты (варианты), способ получения растворимого слитого белка, способ получения полимера спидроинового белка главной ампулярной железы и способ культивирования эукариотических клеток
WO2007141131A1 (en) * 2006-06-08 2007-12-13 Technische Universitaet Muenchen Microfluidic device for controlled aggregation of spider silk
DE102006038445A1 (de) * 2006-08-16 2008-02-21 Gustav Pirazzi & Comp. Kg Verwendung von künstlich hergestellter Spinnenseide
WO2008108838A2 (en) * 2006-11-21 2008-09-12 Charles Stark Draper Laboratory, Inc. Microfluidic devices and methods for fabricating the same
DE102007002222A1 (de) 2007-01-10 2008-07-17 Gustav Pirazzi & Comp. Kg Verwendung von künstlich hergestellter Spinnenseide
AU2008265231B2 (en) * 2007-06-20 2014-05-01 Basf Se Synthetic repetitive proteins, the production and use thereof
EP2475677B1 (en) * 2009-08-26 2018-08-01 Commonwealth Scientific and Industrial Research Organisation Processes for producing silk dope
WO2011069643A2 (en) 2009-12-08 2011-06-16 Amsilk Gmbh Silk protein coatings
CN102946914B (zh) * 2010-04-12 2015-06-03 思百博技术股份公司 方法及组合物
DE202013003445U1 (de) 2012-04-11 2013-04-26 Amsilk Gmbh Staubbeutel
EP3682912B1 (en) 2012-08-17 2025-11-26 AMSilk GmbH Use of self-assembling polypeptides as tissue adhesives
EP2892916B1 (en) * 2012-09-06 2021-08-25 AMSilk GmbH Methods for producing high toughness silk fibres
SG10201703051WA (en) 2012-10-17 2017-06-29 Univ Nanyang Tech Compounds and methods for the production of suckerin and uses thereof
JP5678283B2 (ja) 2012-12-26 2015-02-25 スパイバー株式会社 クモ糸タンパク質フィルム及びその製造方法
EP3000125A4 (en) 2013-05-22 2017-02-08 Transient Electronics, Inc. Controlled transformation of non-transient electronics
EP3060389B1 (en) 2013-10-21 2019-11-20 The North Face Apparel Corp. Functional biomaterial coatings for textiles and other substrates
SG11201704010UA (en) 2014-08-20 2017-06-29 Silk Tech Ltd Fibroin-derived protein composition
CN108431094A (zh) 2015-12-25 2018-08-21 丝芭博株式会社 高分子凝集体的制造方法
SG11201808804TA (en) 2016-04-08 2018-11-29 Univ Cornell A method to enhance wound healing using silk-derived protein
EP3476859A4 (en) 2016-06-23 2019-12-11 Spiber Inc. MODIFIED FIBROIN
CA3033507A1 (en) 2016-08-12 2018-02-15 Silk Technologies, Ltd. Silk-derived protein for treating inflammation
US20180096033A1 (en) * 2016-10-04 2018-04-05 International Business Machines Corporation Query management in database management systems
WO2018087239A1 (en) * 2016-11-11 2018-05-17 Amsilk Gmbh Use of a shrinkable biopolymer fiber as sensor
DE102016222480B4 (de) 2016-11-16 2020-02-13 Adidas Ag Bekleidungsstück, das Spinnenseide aufweist oder Schuh, der Spinnenseide aufweist, und ein entsprechendes Herstellungsverfahren
WO2018229341A1 (en) * 2017-06-13 2018-12-20 Aalto University Foundation Sr. Method for producing a condensed adhesive phase of silk fusion proteins
EP3556914A1 (de) 2018-04-20 2019-10-23 Lenzing Aktiengesellschaft Regenerierte cellulosische formkörper und verfahren zur herstellung regenerierter cellulosischer formkörper
WO2019241859A1 (en) * 2018-06-22 2019-12-26 Natura Cosméticos S.A. Cosmetic composition for treating keratin fibers
WO2022084285A1 (de) 2020-10-20 2022-04-28 Strauch Georg Beschichtetes haar und dessen verwendung
CN116446064B (zh) * 2022-12-29 2025-04-04 宜宾惠美纤维新材料股份有限公司 一种蛹虫草蛋白纤维及其制备方法

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US5994099A (en) * 1997-12-31 1999-11-30 The University Of Wyoming Extremely elastic spider silk protein and DNA coding therefor
FR2774588B1 (fr) * 1998-02-11 2000-05-05 Oreal Composition cosmetique ou dermatologique contenant au moins une proteine de soie d'arachnides naturelle, recombinante ou un analogue
US7157615B2 (en) * 1998-03-17 2007-01-02 Nexia Biotechnologies, Inc. Production of biofilaments in transgenic animals
JP2005502347A (ja) 2001-08-29 2005-01-27 ユニバーシティ オブ ワイオミング クモ糸タンパク質をコードする核酸、ポリペプチド、抗体とそれらの使用方法
AU2003202949A1 (en) * 2002-01-11 2003-07-30 Ali Alwattari Methods and apparatus for spinning spider silk protein
WO2003057727A1 (en) * 2002-01-11 2003-07-17 Nexia Biotechnologies, Inc. Methods of producing silk polypeptides and products thereof
EP1609801A1 (en) * 2004-06-25 2005-12-28 Technische Universität München Proteins of natural origin and materials made therefrom
AU2005263622B2 (en) * 2004-07-22 2012-04-26 Amsilk Gmbh Recombinant spider silk proteins

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108290935A (zh) * 2015-08-10 2018-07-17 赛威克斯材料科学公司 用于制造合成的拖丝蜘蛛丝的组合物和方法
US10981959B2 (en) 2015-08-10 2021-04-20 Seevix Material Sciences Ltd. Compositions and methods for fabricating synthetic dragline spider silk
CN109477252A (zh) * 2016-02-11 2019-03-15 赛威克斯材料科学公司 包括合成拖丝蜘蛛丝的复合材料
US11345727B2 (en) 2016-02-11 2022-05-31 Seevix Material Sciences Ltd. Composite materials comprising synthetic dragline spider silk
US12030919B2 (en) 2016-02-11 2024-07-09 Seevix Material Sciences Ltd. Composite materials comprising synthetic dragline spider silk
CN112567083A (zh) * 2018-04-03 2021-03-26 丝芭博株式会社 高收缩人造丝心蛋白加捻纱及其制造方法、以及人造丝心蛋白加捻纱及其收缩方法
CN112567083B (zh) * 2018-04-03 2023-07-07 丝芭博株式会社 高收缩人造丝心蛋白加捻纱及其制造方法、以及人造丝心蛋白加捻纱及其收缩方法
US12668828B2 (en) 2019-07-04 2026-06-30 Seevix Material Sciences Ltd. Prokaryotic expression system and methods of using the same
US12453688B2 (en) 2020-04-23 2025-10-28 Seevix Material Sciences Ltd. Cosmetic compositions comprising dragline spider silk
CN112680884A (zh) * 2020-12-30 2021-04-20 苏州经贸职业技术学院 一种抗菌口罩材料的制备方法

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Publication number Publication date
US8030024B2 (en) 2011-10-04
WO2006002827A1 (en) 2006-01-12
EP1609801A1 (en) 2005-12-28
US20070196429A1 (en) 2007-08-23
US8097583B2 (en) 2012-01-17
JP4990763B2 (ja) 2012-08-01
US20080021553A1 (en) 2008-01-24
WO2006002853A1 (en) 2006-01-12
EP1778722A1 (en) 2007-05-02
JP2008507260A (ja) 2008-03-13
EP1778849A1 (en) 2007-05-02

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