CN101133053A - 取代的吡啶衍生物 - Google Patents

取代的吡啶衍生物 Download PDF

Info

Publication number
CN101133053A
CN101133053A CNA2006800068313A CN200680006831A CN101133053A CN 101133053 A CN101133053 A CN 101133053A CN A2006800068313 A CNA2006800068313 A CN A2006800068313A CN 200680006831 A CN200680006831 A CN 200680006831A CN 101133053 A CN101133053 A CN 101133053A
Authority
CN
China
Prior art keywords
base
alkene
alkane
alkynes
cycloalkanes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2006800068313A
Other languages
English (en)
Chinese (zh)
Inventor
C·W·托诺
N·坎津
M·罗特兰德
W·P·沃森
D·R·格雷弗
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
H Lundbeck AS
Original Assignee
H Lundbeck AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck AS filed Critical H Lundbeck AS
Publication of CN101133053A publication Critical patent/CN101133053A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNA2006800068313A 2005-03-03 2006-03-02 取代的吡啶衍生物 Pending CN101133053A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200500321 2005-03-03
DKPA200500321 2005-03-03

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN201110168073.8A Division CN102276523B (zh) 2005-03-03 2006-03-02 取代的吡啶衍生物
CN2011103097414A Division CN102516165A (zh) 2005-03-03 2006-03-02 取代的吡啶衍生物

Publications (1)

Publication Number Publication Date
CN101133053A true CN101133053A (zh) 2008-02-27

Family

ID=37908541

Family Applications (3)

Application Number Title Priority Date Filing Date
CN2011103097414A Pending CN102516165A (zh) 2005-03-03 2006-03-02 取代的吡啶衍生物
CNA2006800068313A Pending CN101133053A (zh) 2005-03-03 2006-03-02 取代的吡啶衍生物
CN201110168073.8A Expired - Fee Related CN102276523B (zh) 2005-03-03 2006-03-02 取代的吡啶衍生物

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN2011103097414A Pending CN102516165A (zh) 2005-03-03 2006-03-02 取代的吡啶衍生物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201110168073.8A Expired - Fee Related CN102276523B (zh) 2005-03-03 2006-03-02 取代的吡啶衍生物

Country Status (14)

Country Link
KR (2) KR20070108884A (ru)
CN (3) CN102516165A (ru)
AR (1) AR052931A1 (ru)
BR (1) BRPI0608122A2 (ru)
DK (1) DK2298766T3 (ru)
EA (1) EA016244B1 (ru)
ES (1) ES2433593T3 (ru)
HK (1) HK1164868A1 (ru)
IL (1) IL185113A (ru)
NZ (1) NZ556613A (ru)
PT (1) PT2298766E (ru)
SI (1) SI2298766T1 (ru)
UA (1) UA92340C2 (ru)
ZA (1) ZA200705987B (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114409593B (zh) * 2022-01-20 2024-02-23 上海泾维化工科技有限公司 一种2-氨基-5-甲基吡啶的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60037321T4 (de) * 1999-08-04 2010-01-07 Icagen, Inc. Benzanilide als öffner des kaliumkanals
CA2412208C (en) * 2000-06-29 2009-08-18 Neurosearch A/S Use of 3-substituted oxindole derivatives as kcnq potassium channel modulators
PL372944A1 (en) * 2001-02-20 2005-08-08 Bristol-Myers Squibb Company 2,4-disubstituted pyrimidine-5-carboxamide derivatives as kcnq potassium channel modulators
EP1613303A1 (en) * 2003-03-21 2006-01-11 H. Lundbeck A/S Substituted p-diaminobenzene derivatives
TWI349666B (en) * 2004-03-12 2011-10-01 Lundbeck & Co As H Substituted morpholine and thiomorpholine derivatives

Also Published As

Publication number Publication date
NZ556613A (en) 2010-11-26
BRPI0608122A2 (pt) 2010-11-09
KR20130088905A (ko) 2013-08-08
UA92340C2 (en) 2010-10-25
DK2298766T3 (da) 2013-11-11
AR052931A1 (es) 2007-04-11
EA016244B1 (ru) 2012-03-30
IL185113A (en) 2013-10-31
HK1164868A1 (en) 2012-09-28
EA200701877A1 (ru) 2008-02-28
ZA200705987B (en) 2009-05-27
PT2298766E (pt) 2013-11-07
KR20070108884A (ko) 2007-11-13
SI2298766T1 (sl) 2014-05-30
IL185113A0 (en) 2007-12-03
ES2433593T3 (es) 2013-12-11
CN102516165A (zh) 2012-06-27
CN102276523A (zh) 2011-12-14
CN102276523B (zh) 2014-12-10

Similar Documents

Publication Publication Date Title
JP5237643B2 (ja) 置換されたピリジン誘導体
CN102516204A (zh) 取代的吗啉和硫代吗啉衍生物
EP2468732B1 (en) 1H-Quinazoline-2,4-diones
US7683058B2 (en) Substituted pyrimidine derivatives
US7368472B2 (en) 1,2,4-Triaminobenzene derivatives useful for treating disorders of the central nervous system
CN101906105B (zh) 吡唑并[1，5-a]嘧啶酮衍生物及其药物组合物以及其用途
CN101258133A (zh) 嘧啶衍生物和它们作为kcnq钾通道开放剂的用途
CN102276523B (zh) 取代的吡啶衍生物
TW200307548A (en) Histamine-3 receptor ligands for diabetic conditions
JP2006502102A (ja) １−フェニルアルキル−ピペラジン
CN100448867C (zh) 用于治疗中枢神经系统疾病的1,2,4-三氨基苯衍生物
JP2003246732A (ja) １，２−エタンジオール誘導体またはその塩を含有する神経断裂治療剤

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1117842

Country of ref document: HK

C12 Rejection of a patent application after its publication
RJ01 Rejection of invention patent application after publication

Open date: 20080227

REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1117842

Country of ref document: HK