UA92340C2 - Substituted pyridine derivatives - Google Patents

Substituted pyridine derivatives

Info

Publication number
UA92340C2
UA92340C2 UAA200710648A UAA200710648A UA92340C2 UA 92340 C2 UA92340 C2 UA 92340C2 UA A200710648 A UAA200710648 A UA A200710648A UA A200710648 A UAA200710648 A UA A200710648A UA 92340 C2 UA92340 C2 UA 92340C2
Authority
UA
Ukraine
Prior art keywords
pyridine derivatives
substituted pyridine
openers
treatment
general formula
Prior art date
Application number
UAA200710648A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Кристиан Венсель Торнее
Николай Ханжин
Марио Роттлондер
Вильям Патрик Ватсон
Даниэль Родригес Греве
Original Assignee
Х. Луннбек А/С
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Х. Луннбек А/С filed Critical Х. Луннбек А/С
Publication of UA92340C2 publication Critical patent/UA92340C2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol

Abstract

The present invention relates to pyridine derivatives of the general formula (I) and their use as openers of the KCNQ family potassium ion channels for the treatment of CNS disorders.
UAA200710648A 2005-03-03 2006-02-03 Substituted pyridine derivatives UA92340C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200500321 2005-03-03

Publications (1)

Publication Number Publication Date
UA92340C2 true UA92340C2 (en) 2010-10-25

Family

ID=37908541

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200710648A UA92340C2 (en) 2005-03-03 2006-02-03 Substituted pyridine derivatives

Country Status (14)

Country Link
KR (2) KR20070108884A (en)
CN (3) CN102276523B (en)
AR (1) AR052931A1 (en)
BR (1) BRPI0608122A2 (en)
DK (1) DK2298766T3 (en)
EA (1) EA016244B1 (en)
ES (1) ES2433593T3 (en)
HK (1) HK1164868A1 (en)
IL (1) IL185113A (en)
NZ (1) NZ556613A (en)
PT (1) PT2298766E (en)
SI (1) SI2298766T1 (en)
UA (1) UA92340C2 (en)
ZA (1) ZA200705987B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114409593B (en) * 2022-01-20 2024-02-23 上海泾维化工科技有限公司 Preparation method of 2-amino-5-methylpyridine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003506387A (en) * 1999-08-04 2003-02-18 アイカゲン インコーポレイテッド Benzanilide as a potassium channel opener
MXPA03000032A (en) * 2000-06-29 2003-08-19 Neurosearch As Use of 3-substituted oxindole derivatives as kcnq potassium channel modulators.
MXPA03007395A (en) * 2001-02-20 2003-12-04 Bristol Myers Squibb Co 2,4-disubstituted pyrimidine-5-carboxamide derivatives as kcnq potassium channel modulators.
CA2519582A1 (en) * 2003-03-21 2004-09-30 H. Lundbeck A/S Substituted p-diaminobenzene derivatives
TWI349666B (en) * 2004-03-12 2011-10-01 Lundbeck & Co As H Substituted morpholine and thiomorpholine derivatives

Also Published As

Publication number Publication date
BRPI0608122A2 (en) 2010-11-09
NZ556613A (en) 2010-11-26
AR052931A1 (en) 2007-04-11
EA200701877A1 (en) 2008-02-28
SI2298766T1 (en) 2014-05-30
PT2298766E (en) 2013-11-07
EA016244B1 (en) 2012-03-30
HK1164868A1 (en) 2012-09-28
CN101133053A (en) 2008-02-27
CN102276523B (en) 2014-12-10
ES2433593T3 (en) 2013-12-11
CN102276523A (en) 2011-12-14
KR20130088905A (en) 2013-08-08
DK2298766T3 (en) 2013-11-11
IL185113A (en) 2013-10-31
ZA200705987B (en) 2009-05-27
CN102516165A (en) 2012-06-27
IL185113A0 (en) 2007-12-03
KR20070108884A (en) 2007-11-13

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