EA200701877A1 - Derivatives of Substituted Pyridines - Google Patents
Derivatives of Substituted PyridinesInfo
- Publication number
- EA200701877A1 EA200701877A1 EA200701877A EA200701877A EA200701877A1 EA 200701877 A1 EA200701877 A1 EA 200701877A1 EA 200701877 A EA200701877 A EA 200701877A EA 200701877 A EA200701877 A EA 200701877A EA 200701877 A1 EA200701877 A1 EA 200701877A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- derivatives
- substituted pyridines
- openers
- treatment
- general formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Настоящее изобретение относится к производным пиридина общей формулы I и их применению в качестве открывателей каналов калиевых ионов семейства KCNQ для лечения нарушений ЦНС.The present invention relates to pyridine derivatives of general formula I and their use as openers of potassium ion channels of the KCNQ family for the treatment of CNS disorders.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200500321 | 2005-03-03 | ||
PCT/DK2006/000123 WO2006092143A1 (en) | 2005-03-03 | 2006-03-02 | Substituted pyridine derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
EA200701877A1 true EA200701877A1 (en) | 2008-02-28 |
EA016244B1 EA016244B1 (en) | 2012-03-30 |
Family
ID=37908541
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200701877A EA016244B1 (en) | 2005-03-03 | 2006-03-02 | Substituted pyridine derivatives |
Country Status (14)
Country | Link |
---|---|
KR (2) | KR20070108884A (en) |
CN (3) | CN102276523B (en) |
AR (1) | AR052931A1 (en) |
BR (1) | BRPI0608122A2 (en) |
DK (1) | DK2298766T3 (en) |
EA (1) | EA016244B1 (en) |
ES (1) | ES2433593T3 (en) |
HK (1) | HK1164868A1 (en) |
IL (1) | IL185113A (en) |
NZ (1) | NZ556613A (en) |
PT (1) | PT2298766E (en) |
SI (1) | SI2298766T1 (en) |
UA (1) | UA92340C2 (en) |
ZA (1) | ZA200705987B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114409593B (en) * | 2022-01-20 | 2024-02-23 | 上海泾维化工科技有限公司 | Preparation method of 2-amino-5-methylpyridine |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE380176T1 (en) * | 1999-08-04 | 2007-12-15 | Icagen Inc | BENZANILIDE AS AN OPENER OF THE POTASSIUM CHANNEL |
NZ522794A (en) * | 2000-06-29 | 2005-04-29 | Neurosearch As | Use of 3-substituted oxindole derivatives as KCNQ potassium channel modulators |
EP1361879A1 (en) * | 2001-02-20 | 2003-11-19 | Bristol-Myers Squibb Company | 2,4-disubstituted pyrimidine-5-carboxamide derivatives as kcnq potassium channel modulators |
WO2004082677A1 (en) * | 2003-03-21 | 2004-09-30 | H. Lundbeck A/S | Substituted p-diaminobenzene derivatives |
TWI349666B (en) * | 2004-03-12 | 2011-10-01 | Lundbeck & Co As H | Substituted morpholine and thiomorpholine derivatives |
-
2006
- 2006-02-03 UA UAA200710648A patent/UA92340C2/en unknown
- 2006-03-02 BR BRPI0608122-3A patent/BRPI0608122A2/en not_active IP Right Cessation
- 2006-03-02 ZA ZA200705987A patent/ZA200705987B/en unknown
- 2006-03-02 KR KR1020077019782A patent/KR20070108884A/en not_active Application Discontinuation
- 2006-03-02 KR KR1020137019572A patent/KR20130088905A/en not_active Application Discontinuation
- 2006-03-02 NZ NZ556613A patent/NZ556613A/en not_active IP Right Cessation
- 2006-03-02 ES ES10182072T patent/ES2433593T3/en active Active
- 2006-03-02 AR ARP060100790A patent/AR052931A1/en unknown
- 2006-03-02 CN CN201110168073.8A patent/CN102276523B/en not_active Expired - Fee Related
- 2006-03-02 EA EA200701877A patent/EA016244B1/en not_active IP Right Cessation
- 2006-03-02 SI SI200631682T patent/SI2298766T1/en unknown
- 2006-03-02 DK DK10182072.8T patent/DK2298766T3/en active
- 2006-03-02 CN CNA2006800068313A patent/CN101133053A/en active Pending
- 2006-03-02 CN CN2011103097414A patent/CN102516165A/en active Pending
- 2006-03-02 PT PT101820728T patent/PT2298766E/en unknown
-
2007
- 2007-08-07 IL IL185113A patent/IL185113A/en not_active IP Right Cessation
-
2012
- 2012-06-07 HK HK12105602.5A patent/HK1164868A1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR20130088905A (en) | 2013-08-08 |
CN102276523A (en) | 2011-12-14 |
NZ556613A (en) | 2010-11-26 |
PT2298766E (en) | 2013-11-07 |
CN102516165A (en) | 2012-06-27 |
IL185113A0 (en) | 2007-12-03 |
KR20070108884A (en) | 2007-11-13 |
EA016244B1 (en) | 2012-03-30 |
ZA200705987B (en) | 2009-05-27 |
ES2433593T3 (en) | 2013-12-11 |
BRPI0608122A2 (en) | 2010-11-09 |
CN102276523B (en) | 2014-12-10 |
SI2298766T1 (en) | 2014-05-30 |
DK2298766T3 (en) | 2013-11-11 |
IL185113A (en) | 2013-10-31 |
HK1164868A1 (en) | 2012-09-28 |
CN101133053A (en) | 2008-02-27 |
AR052931A1 (en) | 2007-04-11 |
UA92340C2 (en) | 2010-10-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): BY |
|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ KZ KG MD TJ TM RU |