CN101129493B - Antineoplastic anti-AIDS pharmaceutical composition and method of preparing the same - Google Patents
Antineoplastic anti-AIDS pharmaceutical composition and method of preparing the same Download PDFInfo
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- CN101129493B CN101129493B CN2007100589656A CN200710058965A CN101129493B CN 101129493 B CN101129493 B CN 101129493B CN 2007100589656 A CN2007100589656 A CN 2007100589656A CN 200710058965 A CN200710058965 A CN 200710058965A CN 101129493 B CN101129493 B CN 101129493B
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- cortex moutan
- herba taraxaci
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Abstract
The invention relates to an antineoplastic pharmaceutical composition for treating AIDS and process for preparation, wherein the constituents include fine Chinese caterpillar fungus 3-15%, red ginseng 20-40%, notoginseng 5-30%, bark of peony root 5-20%, dandehon herb 12-40% and scutellaria root extract 5-20%.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition and preparation method, particularly relate to a kind of antineoplastic anti-AIDS pharmaceutical composition and preparation method.
Background technology
Acquired immune deficiency syndrome (AIDS), tumor have become the 21 century mankind's common disaster.Chinese medicine is thought: acquired immune deficiency syndrome (AIDS), tumor are variability extracellular toxin intrusion body and cause human body vital QI being weakened and pathogen being violent, qi depression to blood stasis, scorchingly hot interior knot, vigour to dry up and fall ill.Modern medicine treatment acquired immune deficiency syndrome (AIDS), tumor all use put, amic therapy method, in kill virus, keeps human life activity's cell in a large number and also killed, even its quantity of being killed is greater than sick cell.So far the good medicine that does not still have these diseases of radical cure.Therefore seeking a kind of anti-AIDS, antitumor effectively and the medicine little to the human body toxic and side effects, is problem demanding prompt solution.
Summary of the invention
The objective of the invention is to overcome deficiency of the prior art, a kind of antineoplastic anti-AIDS pharmaceutical composition is provided.
Second purpose of the present invention provides a kind of preparation method of antineoplastic anti-AIDS pharmaceutical composition.
Technical scheme of the present invention is summarized as follows:
A kind of antineoplastic anti-AIDS pharmaceutical composition is made up of following component: Cordyceps 3%-15%, Radix Ginseng Rubra 20%-40%, Radix Notoginseng 5%-30%, Cortex Moutan 5%-20%, Herba Taraxaci 12%-40%, Radix Scutellariae extract 5%-20% by weight percentage.
Preferably: described Cordyceps is 6.24%, and Radix Ginseng Rubra is 31.25%, and Radix Notoginseng is 10.42%, and Cortex Moutan is 10.42%, and Herba Taraxaci is 31.25%, and Radix Scutellariae extract is 10.42%.
Preferably can also be: described Cordyceps be 8%, and Radix Ginseng Rubra is 25%, and Radix Notoginseng is 30%, and Cortex Moutan is 12%, and Herba Taraxaci is 12%, and Radix Scutellariae extract is 13%.
A kind of preparation method of antineoplastic anti-AIDS pharmaceutical composition comprises the steps: that (1) takes by weighing by weight percentage: Cordyceps 3%-15%, Radix Ginseng Rubra 20%-40%, Radix Notoginseng 5%-30%, Cortex Moutan 5%-20%, Herba Taraxaci 12%-40%, Radix Scutellariae extract 5%-20%; (2) be 1 by weight: 4-8 ratio doubly at every turn, with the described Cortex Moutan concentration expressed in percentage by volume ethanol water reflux that is 50%-90% 1-4 time, return time is 1-6 hour, extracting solution filters, filtrate recycling ethanol and when being concentrated into 80 ℃ relative density be 1.00-1.20, spray drying gets Cortex Moutan extract; It is 1 by weight: the ratio of 3-10 at every turn, with the described Herba Taraxaci concentration expressed in percentage by volume ethanol water reflux that is 50%-95% 1-4 time, return time is 1-4 hour, extracting solution filters, filtrate recycling ethanol and when being concentrated into 80 ℃ relative density be 1.00-1.20, carry out spray drying, get Herba Taraxaci extract; (3) with described Cordyceps, Radix Ginseng Rubra, Radix Notoginseng, Radix Scutellariae extract is ground into fine powder, with Cortex Moutan extract and Herba Taraxaci extract mix homogeneously, makes a kind of antineoplastic anti-AIDS pharmaceutical composition.
A kind of preparation method of antineoplastic anti-AIDS pharmaceutical composition, preferably described step is: (1) takes by weighing by weight percentage: Cordyceps 6.24%, Radix Ginseng Rubra 31.25%, Radix Notoginseng 10.42%, Cortex Moutan 10.42%, Herba Taraxaci 31.25%, Radix Scutellariae extract 10.42%; (2) with described Cortex Moutan concentration expressed in percentage by volume be 60% ethanol water reflux 2 times, add for the first time the ethanol water amount and be 6 times of Cortex Moutan weight, refluxed 3 hours, add for the second time amount of alcohol and be 4 times of Cortex Moutan weight, refluxed 2 hours, extracting solution filters, filtrate recycling ethanol and when being concentrated into 80 ℃ relative density be 1.00-1.10, carry out spray drying, get Cortex Moutan extract; With described Herba Taraxaci concentration expressed in percentage by volume is 85% ethanol water reflux 2 times, add for the first time amount of alcohol and be 8 times of Herba Taraxaci weight, refluxed 2 hours, add for the second time amount of alcohol and be 5 times of Herba Taraxaci weight, refluxed 2 hours, extracting solution filters, filtrate recycling ethanol and when being concentrated into 80 ℃ relative density be 1.00-1.10, carry out spray drying; (3) with described Cordyceps, Radix Ginseng Rubra, Radix Notoginseng, Radix Scutellariae extract is ground into fine powder, with Cortex Moutan extract and Herba Taraxaci extract mix homogeneously, makes a kind of antineoplastic anti-AIDS pharmaceutical composition.
Preferably can also be: described Cordyceps be 8%, and Radix Ginseng Rubra is 25%, and Radix Notoginseng is 30%, and Cortex Moutan is 12%, and Herba Taraxaci is 12%, and Radix Scutellariae extract is 13%.
A kind of antineoplastic anti-AIDS pharmaceutical composition of the present invention is a kind of treatment with prevent AIDS that poison carries, acquired immune deficiency syndrome (AIDS), malignant tumor, leukemia and deficient, the worn with age pure Chinese medicinal preparation of prolonged illness.This medical instrument has the effect of strengthening by means of tonics, strengthening the body resistance, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing; Product absorbance height, taking convenience and economy.
The specific embodiment
The present invention is further illustrated below in conjunction with specific embodiment.
Embodiment 1
A kind of antineoplastic anti-AIDS pharmaceutical composition is made up of following component: Cordyceps 6.24%, Radix Ginseng Rubra 31.25%, Radix Notoginseng 10.42%, Cortex Moutan 10.42%, Herba Taraxaci 31.25%, Radix Scutellariae extract 10.42% by weight percentage.
Embodiment 2
A kind of antineoplastic anti-AIDS pharmaceutical composition is made up of following component: Cordyceps 3%, Radix Ginseng Rubra 40%, Radix Notoginseng 10%, Cortex Moutan 20%, Herba Taraxaci 20%, Radix Scutellariae extract 7% by weight percentage.
Embodiment 3
A kind of antineoplastic anti-AIDS pharmaceutical composition is made up of following component: Cordyceps 15%, Radix Ginseng Rubra 20%, Radix Notoginseng 5%, Cortex Moutan 5%, Herba Taraxaci 40%, Radix Scutellariae extract 15% by weight percentage.
Embodiment 4
A kind of antineoplastic anti-AIDS pharmaceutical composition is made up of following component: Cordyceps 10%, Radix Ginseng Rubra 20%, Radix Notoginseng 20%, Cortex Moutan 10%, Herba Taraxaci 20%, Radix Scutellariae extract 20% by weight percentage.
Embodiment 5
A kind of antineoplastic anti-AIDS pharmaceutical composition is made up of following component: Cordyceps 15%, Radix Ginseng Rubra 30%, Radix Notoginseng 10%, Cortex Moutan 15%, Herba Taraxaci 25%, Radix Scutellariae extract 5% by weight percentage.
Embodiment 6
A kind of antineoplastic anti-AIDS pharmaceutical composition is made up of following component: Cordyceps 8%, Radix Ginseng Rubra 25%, Radix Notoginseng 30%, Cortex Moutan 12%, Herba Taraxaci 12%, Radix Scutellariae extract 13% by weight percentage.
A kind of antineoplastic anti-AIDS pharmaceutical composition of embodiment 1-embodiment 6 can after taking by weighing by weight percentage, be pulverized according to a conventional method, and mix homogeneously is made.
Embodiment 7
A kind of preparation method of antineoplastic anti-AIDS pharmaceutical composition, adopt following steps: (1) takes by weighing by weight percentage: Cordyceps 6.24%, Radix Ginseng Rubra 31.25%, Radix Notoginseng 10.42%, Cortex Moutan 10.42%, Herba Taraxaci 31.25%, Radix Scutellariae extract 10.42%; (2) with described Cortex Moutan concentration expressed in percentage by volume be 60% ethanol water reflux 2 times, add for the first time the ethanol water amount and be 6 times of Cortex Moutan weight, refluxed 3 hours, add for the second time amount of alcohol and be 4 times of Cortex Moutan weight, refluxed 2 hours, extracting solution filters, filtrate recycling ethanol and when being concentrated into 80 ℃ relative density be 1.00-1.10, carry out spray drying, get Cortex Moutan extract; With described Herba Taraxaci concentration expressed in percentage by volume is 85% ethanol water reflux 2 times, add for the first time amount of alcohol and be 8 times of Herba Taraxaci weight, refluxed 2 hours, add for the second time amount of alcohol and be 5 times of Herba Taraxaci weight, refluxed 2 hours, extracting solution filters, filtrate recycling ethanol and when being concentrated into 80 ℃ relative density be 1.00-1.10, carry out spray drying; (3) with described Cordyceps, Radix Ginseng Rubra, Radix Notoginseng, Radix Scutellariae extract is ground into fine powder, with Cortex Moutan extract and Herba Taraxaci extract mix homogeneously, makes a kind of antineoplastic anti-AIDS pharmaceutical composition.
Embodiment 8
A kind of preparation method of antineoplastic anti-AIDS pharmaceutical composition, adopt following steps:
(1) takes by weighing by weight percentage: Cordyceps 8%, Radix Ginseng Rubra 25%, Radix Notoginseng 30%, Cortex Moutan 12%, Herba Taraxaci 12%, Radix Scutellariae extract 13%;
Step (2) (3) is with embodiment 7.
Embodiment 9
A kind of preparation method of antineoplastic anti-AIDS pharmaceutical composition, adopt following steps: (1) takes by weighing embodiment 6 described each component by weight percentage; (2) being 1: 4 times ratio by weight, is 90% ethanol water reflux 1 time with described Cortex Moutan concentration expressed in percentage by volume, and return time is 6 hours, extracting solution filters, filtrate recycling ethanol and relative density 1.00 when being concentrated into 80 ℃, spray drying, Cortex Moutan extract; Be 1: 3 ratio by weight, be 95% ethanol water reflux 1 time with described Herba Taraxaci concentration expressed in percentage by volume at every turn, and return time is 4 hours, extracting solution filters, filtrate recycling ethanol and relative density 1.00 when being concentrated into 80 ℃ are carried out spray drying, Herba Taraxaci extract; (3) with described Cordyceps, Radix Ginseng Rubra, Radix Notoginseng, Radix Scutellariae extract is ground into fine powder, and with Cortex Moutan extract, Herba Taraxaci extract, mix homogeneously is made a kind of antineoplastic anti-AIDS pharmaceutical composition.
Embodiment 10
A kind of preparation method of antineoplastic anti-AIDS pharmaceutical composition, adopt following steps: (1) takes by weighing embodiment 3 described each component by weight percentage; (2) be 1: 8 times ratio by weight, be 50% ethanol water reflux 4 times with described Cortex Moutan concentration expressed in percentage by volume at every turn, and return time is 1 hour, extracting solution filters, filtrate recycling ethanol and relative density 1.20 when being concentrated into 80 ℃, spray drying, Cortex Moutan extract; Be 1: 10 ratio by weight, be 50% ethanol water reflux 4 times with described Herba Taraxaci concentration expressed in percentage by volume at every turn, and return time is 1 hour, extracting solution filters, filtrate recycling ethanol and relative density 1.20 when being concentrated into 80 ℃ are carried out spray drying, Herba Taraxaci extract; (3) with described Cordyceps, Radix Ginseng Rubra, Radix Notoginseng, Radix Scutellariae extract is ground into fine powder, and with Cortex Moutan extract, Herba Taraxaci extract, mix homogeneously is made a kind of antineoplastic anti-AIDS pharmaceutical composition.
Embodiment 11
A kind of preparation method of antineoplastic anti-AIDS pharmaceutical composition takes by weighing embodiment 4 described each component, makes by step (2), (3) of embodiment 7.
Embodiment 12
A kind of preparation method of antineoplastic anti-AIDS pharmaceutical composition takes by weighing embodiment 5 described each component, makes by step (2), (3) of embodiment 8.
Embodiment 13
A kind of preparation method of antineoplastic anti-AIDS pharmaceutical composition, adopt following steps: (1) takes by weighing embodiment 1 described each component by weight percentage; (2) being 1: 6 times ratio by weight, is 75% ethanol water reflux 2 times with described Cortex Moutan concentration expressed in percentage by volume, and return time is 3 hours, extracting solution filters, filtrate recycling ethanol and relative density 1.15 when being concentrated into 80 ℃, spray drying, Cortex Moutan extract; Be 1: 5 ratio by weight, be 75% ethanol water reflux 2 times with described Herba Taraxaci concentration expressed in percentage by volume at every turn, and return time is 2 hours, extracting solution filters, filtrate recycling ethanol and relative density 1.15 when being concentrated into 80 ℃ are carried out spray drying, Herba Taraxaci extract; (3) with described Cordyceps, Radix Ginseng Rubra, Radix Notoginseng, Radix Scutellariae extract is ground into fine powder, and with Cortex Moutan extract, Herba Taraxaci extract, mix homogeneously is made a kind of antineoplastic anti-AIDS pharmaceutical composition.
A kind of antineoplastic anti-AIDS pharmaceutical composition is added starch 16 times to Radix Scutellariae extract weight, make capsule (the holy health-care capsule of universe health).
Embodiment 14
A kind of preparation method of antineoplastic anti-AIDS pharmaceutical composition, adopt following steps: (1) takes by weighing embodiment 2 described each component by weight percentage; (2), (3) are with embodiment 13.
A kind of antineoplastic anti-AIDS pharmaceutical composition is added starch 10 times to Radix Scutellariae extract weight, make capsule.
Embodiment 15
A kind of preparation method of antineoplastic anti-AIDS pharmaceutical composition, adopt following steps: (1) takes by weighing embodiment 3 described each component by weight percentage; (2), (3) are with embodiment 13.
A kind of antineoplastic anti-AIDS pharmaceutical composition is added starch 20 times to Radix Scutellariae extract weight, make capsule.
Can also be that pharmaceutical composition with the preparation method preparation of a kind of antineoplastic anti-AIDS pharmaceutical composition of a kind of antineoplastic anti-AIDS pharmaceutical composition of embodiment 1-embodiment 6 and embodiment 7-embodiment 12 adds pharmacy acceptable auxiliary (as starch, dextrin, magnesium stearate, hydroxypropyl starch sodium, sodium carboxymethyl cellulose, carboxymethylcellulose calcium, lactose, pregelatinized Starch etc.) and makes granule, encapsulated, or tabletting becomes tablet.
Also can make pill, soft capsule, granule, slow releasing tablet, drop pill etc. according to a conventional method or make syrup or mixture etc.
Embodiment 16
A kind of antineoplastic anti-AIDS pharmaceutical composition of the present invention (embodiment 13 preparations) (the holy health-care capsule of universe health) treatment type b chronic viral hepatitis compares clinical experiment with FUGANNING PIAN.
Universe Kang Shengbao group: capsule, ante cibum is oral, and every day 3 times, each 2, the course of treatment 1 was to 3 months.The Fuganning group: tablet, oral meal, every day 1 time, each 6, the course of treatment 1 was to 3 months.The result: universe Kang Shengbao group chronic persistent hepatitis 100 examples, after treatment, 14 routine produce effects, 19 examples take a turn for the better, effective percentage 33%, chronic active hepatitis 25 examples, 4 routine produce effects, 9 examples take a turn for the better effective percentage 52%.Fuganning group chronic persistent hepatitis 106 examples, 4 routine produce effects, 7 examples take a turn for the better, effective percentage 10.4%, chronic active hepatitis 19 examples, 2 routine produce effects, 4 examples take a turn for the better effective percentage 31.6%.
A kind of antineoplastic anti-AIDS pharmaceutical composition of the present invention (the holy health-care capsule of universe health) treatment 3 routine late malignant tumour patients, wherein 1 routine osteocarcinoma and 1 routine pulmonary carcinoma have mitigation, and the multiple transfer pulmonary carcinoma of 1 routine carcinoma of prostate is through treating 2 years, and focus dissipates fully.
The intravital nef gene of HIV sufferers has the effect that impels HIV (human immunodeficiency virus) (Human Immunodeficiency Virus) to breed rapidly.Through the effect of a kind of antineoplastic anti-AIDS pharmaceutical composition (the holy health-care capsule of universe health) anti-AIDS has been carried out clinical observation, the nef gene of taking 16 HIV sufferers that the holy health-care capsule of universe health more than 7 years, the state of an illness take a turn for the better is to some extent analyzed, be found that the intravital nef gene of 14 people is destroyed among them.This shows that the holy health-care capsule of universe health can destroy the nef gene, thus the breeding of containment HIV (human immunodeficiency virus) (Human Immunodeficiency Virus).
Clinical experiment shows that the holy health-care capsule of universe health has significant protection and facilitation to hemopoietic function of bone marrow.The bone marrow injury that effectively prevention is put, chemotherapy causes, alleviate put, chemotherapy is to the injury that peripheral blood cells causes, and helps putting, the finishing of chemotherapy cycles, and improves clinical efficacy.Can protect gastric mucosa effectively, improve gastrointestinal function, stimulating appetite and dietary amount, obviously alleviate put, gastrointestinal side effect that chemotherapy causes.Can increase cancer patient specificity and non-specific immunity.Strengthen patient's body constitution, disease resistance enhancemen reduces infection chance.Not only can tonification strong, can protect also that organ function is avoided putting, the infringement of chemotherapy.
The present invention is pure green Chinese prescription, and medication is superior.Consolidate QI invigorating with Cordyceps, Radix Ginseng Rubra, increase first tonifying YIN, improve function comprehensively and be monarch drug altogether; With Radix Notoginseng, Cortex Moutan blood circulation promoting and blood stasis dispelling, promoting the circulation of blood removing heat from blood, hemostasis, accent blood, the analgesia relieving convulsion; With Herba Taraxaci, Radix Scutellariae heat-clearing and toxic substances removing, remove relieving internal heat in internal organs and the blood, be the medicine of minister assistant altogether.Full side amounts to the effect that consolidates tonifying YIN, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing.
A kind of antineoplastic anti-AIDS pharmaceutical composition of the present invention is widely applicable, cures the disease, keeps fit in one.Can improve symptom for acquired immune deficiency syndrome (AIDS), tumor patient, reduce or remove put, chemotherapy is to the infringement of human body, effectively life-saving; For worn with age, the weakness due to chronic disease person can improve, strengthen body immunity, regulates the human body functions of immune system, life prolonging consolidates tonifying YIN, improves sleep, improves quality of life.
Pharmacological evaluation is found
(1) a kind of antineoplastic anti-AIDS pharmaceutical composition of the present invention (the holy health-care capsule of universe health) can significantly improve the phagocytic rate and the phagocytic index of the macrophage of mice, improve total white blood cells in the peripheral blood, reduce leukocytic movement index, mice body endoantigen is had obvious facilitation in conjunction with the generation of cell.The holy health-care capsule of proof universe health has certain immunoregulation effect.
(2) the holy health-care capsule of universe health can obviously improve the activity of the SOD in rat cerebral tissue and the blood, significantly reduces the content of Lpo in cerebral tissue and the blood, has anti-aging effects.
(3) the holy health-care capsule of universe health can improve the corticosterone content of serum, promotes body nucleic acid and proteinic metabolism, and mice is had tangible tumor-inhibiting action, and tumour inhibiting rate can reach 45.71%.
Embodiment 17
The holy health-care capsule inspection of universe health: should meet every regulation relevant under the capsule item (" appendix IL of Chinese pharmacopoeia version in 2005).
Moisture: measure according to aquametry, must not cross 9.0%.
Content uniformity: the content uniformity limit should indicate loading amount (or average loading amount) ± 10% in.
Disintegration: disintegrate fully in 30 minutes.
Limit test of microbe: measure according to microbial limit test,
Bacterial population must not be crossed 10000/g;
Mycete and yeast must not be crossed 100/g;
The every 1g of escherichia coli must not detect;
Coliform should be less than 100/g.
Function cures mainly: heat-clearing and toxic substances removing, strengthening the body resistance, strengthening by means of tonics, life lengthening; This product has the regeneration of the human body of helping vigour, improves function, and the blood circulation promoting and blood stasis dispelling eliminating stagnation is removed blood dirt in the blood vessel, the effect of dual regulation immunity; Can improve cancer patient and AIDS VICTIMS's various symptoms, and effectively prolong above two kinds of crowds' life-span.
Usage and dosage: oral.One time 2,3 times on the one.
Specification: every dress 0.4g.
Claims (6)
1. antineoplastic anti-AIDS pharmaceutical composition is characterized in that being made up of following component by weight percentage: Cordyceps 3%-15%, Radix Ginseng Rubra 20%-40%, Radix Notoginseng 5%-30%, Cortex Moutan 5%-20%, Herba Taraxaci 12%-40%, Radix Scutellariae extract 5%-20%.
2. a kind of antineoplastic anti-AIDS pharmaceutical composition according to claim 1 is characterized in that described Cordyceps is 6.24%, and Radix Ginseng Rubra is 31.25%, Radix Notoginseng is 10.42%, Cortex Moutan is 10.42%, and Herba Taraxaci is 31.25%, and Radix Scutellariae extract is 10.42%.
3. a kind of antineoplastic anti-AIDS pharmaceutical composition according to claim 1 is characterized in that described Cordyceps is 8%, and Radix Ginseng Rubra is 25%, and Radix Notoginseng is 30%, and Cortex Moutan is 12%, and Herba Taraxaci is 12%, and Radix Scutellariae extract is 13%.
4. the preparation method of an antineoplastic anti-AIDS pharmaceutical composition, it is characterized in that comprising the steps: that (1) takes by weighing by weight percentage: Cordyceps 3%-15%, Radix Ginseng Rubra 20%-40%, Radix Notoginseng 5%-30%, Cortex Moutan 5%-20%, Herba Taraxaci 12%-40%, Radix Scutellariae extract 5%-20%; (2) be 1 by weight: 4-8 ratio doubly at every turn, with the described Cortex Moutan concentration expressed in percentage by volume ethanol water reflux that is 50%-90% 1-4 time, return time is 1-6 hour, extracting solution filters, filtrate recycling ethanol and when being concentrated into 80 ℃ relative density be 1.00-1.20, spray drying gets Cortex Moutan extract; It is 1 by weight: the ratio of 3-10 at every turn, with the described Herba Taraxaci concentration expressed in percentage by volume ethanol water reflux that is 50%-95% 1-4 time, return time is 1-4 hour, extracting solution filters, filtrate recycling ethanol and when being concentrated into 80 ℃ relative density be 1.00-1.20, carry out spray drying, get Herba Taraxaci extract; (3) with described Cordyceps, Radix Ginseng Rubra, Radix Notoginseng, Radix Scutellariae extract is ground into fine powder, with Cortex Moutan extract and Herba Taraxaci extract mix homogeneously, makes a kind of antineoplastic anti-AIDS pharmaceutical composition.
5. the preparation method of a kind of antineoplastic anti-AIDS pharmaceutical composition according to claim 4, it is characterized in that described step is: (1) takes by weighing by weight percentage: Cordyceps 6.24%, Radix Ginseng Rubra 31.25%, Radix Notoginseng 10.42%, Cortex Moutan 10.42%, Herba Taraxaci 31.25%, Radix Scutellariae extract 10.42%; (2) with described Cortex Moutan concentration expressed in percentage by volume be 60% ethanol water reflux 2 times, add for the first time the ethanol water amount and be 6 times of Cortex Moutan weight, refluxed 3 hours, add for the second time amount of alcohol and be 4 times of Cortex Moutan weight, refluxed 2 hours, extracting solution filters, filtrate recycling ethanol and when being concentrated into 80 ℃ relative density be 1.00-1.10, carry out spray drying, get Cortex Moutan extract; With described Herba Taraxaci concentration expressed in percentage by volume is 85% ethanol water reflux 2 times, add for the first time amount of alcohol and be 8 times of Herba Taraxaci weight, refluxed 2 hours, add for the second time amount of alcohol and be 5 times of Herba Taraxaci weight, refluxed 2 hours, extracting solution filters, filtrate recycling ethanol and when being concentrated into 80 ℃ relative density be 1.00-1.10, carry out spray drying; (3) with described Cordyceps, Radix Ginseng Rubra, Radix Notoginseng, Radix Scutellariae extract is ground into fine powder, with Cortex Moutan extract and Herba Taraxaci extract mix homogeneously, makes a kind of antineoplastic anti-AIDS pharmaceutical composition.
6. the preparation method of a kind of antineoplastic anti-AIDS pharmaceutical composition according to claim 4 is characterized in that described Cordyceps is 8%, and Radix Ginseng Rubra is 25%, and Radix Notoginseng is 30%, and Cortex Moutan is 12%, and Herba Taraxaci is 12%, and Radix Scutellariae extract is 13%.
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| CN1331995A (en) * | 2001-05-18 | 2002-01-23 | 吉林省九台市肺癌药物研究所 | Chinese medicine composition for treating lung cancer |
| CN1559572A (en) * | 2004-03-05 | 2005-01-05 | 陈大刚 | Compound Sanhuang powder |
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| CN1331995A (en) * | 2001-05-18 | 2002-01-23 | 吉林省九台市肺癌药物研究所 | Chinese medicine composition for treating lung cancer |
| CN1559572A (en) * | 2004-03-05 | 2005-01-05 | 陈大刚 | Compound Sanhuang powder |
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