CN101112572A - Chinese traditional medicine preparations for treating cheloid - Google Patents

Chinese traditional medicine preparations for treating cheloid Download PDF

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Publication number
CN101112572A
CN101112572A CNA2007101209156A CN200710120915A CN101112572A CN 101112572 A CN101112572 A CN 101112572A CN A2007101209156 A CNA2007101209156 A CN A2007101209156A CN 200710120915 A CN200710120915 A CN 200710120915A CN 101112572 A CN101112572 A CN 101112572A
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China
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chinese medicine
traditional chinese
keloid
rhizoma
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CNA2007101209156A
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Chinese (zh)
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Priority to CNA2007101209156A priority Critical patent/CN101112572A/en
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Abstract

The present invention relates to a traditional Chinese medicine preparation for treating keloid, which takes more than 10 Chinese herbal medicines of common burreed rhizome, zedoary, peach seed, salvia miltiorrhiza etc. as the raw materials. The present invention has the effects of promoting blood circulation, removing blood stasis, activating qi and resolving hard mass. Based on the differential treatment of the traditional Chinese medicine, the invention is developed by combining the latest scientific research results with the traditional Chinese medicine. The present invention aims at providing the traditional Chinese medicine preparation for treating keloid. The present invention is characterized by accurate efficacy, safety, convenience, no toxicity or side effects and low price.

Description

A kind of Chinese medicine preparation for the treatment of keloid
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of keloid, is that a kind of keloid for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Keloid claims " the Eriocheir sinensis worm is swollen " again, is a kind of optimum fibrous connective tissue hypertrophy of skin histology.Keloid is not subjected to the restriction of age or sex.Some race, especially this disease takes place in Black people Geng Yi.Keloid also more easily takes place in some patient's family.The traditional Chinese medical science is called " meat Testudinis skin ulcer " or " kerf disease ".The pathogenesis of keloid is also not fully aware of, but mainly is the relation of scar diathesis.Stimulate or exopathogenic factor for the inoperative external force of common people, and can suffer from keloid the people of scar diathesis.Common factor has: operation back, wound, scratch, inject, burn, scald, insect bite and external escharotica etc., all can cause keloid.Keloid also can take place in dermatosis affected parts such as acne, variola, chickenpox, eczema, dermatitis, lupus vulgaris, herpes zoster, syphilelcosis, skin infection.The traditional Chinese medical science thinks that primary disease is many because of congenital factors, or owing to golden sword is hindered, or because burn due to hot liquid or fire, residual poison is unclean, is subjected to exopathogen invasion skin again, causes damp and hot rich knot, and coagulation of QI-blood forms.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of keloid.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by following raw materials by weight proportions:
0.1~2 part of 0.1~2 part of Cortex Moutan of 1.5~6 parts of rhizoma sparganic of Radix Salviae Miltiorrhizae
0.1~2 part of 0.1~2 part of Semen Vaccariae of 1.0~4 parts of Rhizoma Curcumae of Pericarpium Citri Reticulatae
0.1~2 part of 0.1~2 part of Fructus Aurantii of 1.0~4 parts of Semen Persicaes of Radix Paeoniae Rubra
0.1~1 part of 0.1~2 part of Rhizoma Pinelliae Preparatum of 1.0~4 parts of Flos Carthamis of Radix Scrophulariae.
The weight proportion of each crude drug of optimization formula of the present invention is:
0.5~1.5 part of 0.5~1.5 part of Cortex Moutan of 2.5~3.5 parts of rhizoma sparganic of Radix Salviae Miltiorrhizae
0.5~1.5 part of 0.5~1.5 part of Semen Vaccariae of 1.5~2.5 parts of Rhizoma Curcumae of Pericarpium Citri Reticulatae
0.5~1.5 part of 0.5~1.5 part of Fructus Aurantii of 1.5~2.5 parts of Semen Persicaes of Radix Paeoniae Rubra
0.3~0.7 part of 0.5~1.5 part of Rhizoma Pinelliae Preparatum of 1.5~2.5 parts of Flos Carthamis of Radix Scrophulariae.
The weight proportion of each crude drug of optimum formula of the present invention is:
1 part of 1 part of Cortex Moutan of 3 parts of rhizoma sparganic of Radix Salviae Miltiorrhizae
1 part of 1 part of Semen Vaccariae of 2 parts of Rhizoma Curcumae of Pericarpium Citri Reticulatae
1 part of 1 part of Fructus Aurantii of 2 parts of Semen Persicaes of Radix Paeoniae Rubra
0.5 part of 1 part of Rhizoma Pinelliae Preparatum of 2 parts of Flos Carthamis of Radix Scrophulariae.
Drug action mechanism among the present invention is as follows:
Radix Salviae Miltiorrhizae property of medicine hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Have blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, the effect of removing heat from blood eliminating carbuncle.Can treat menoxenia, dysmenorrhea, amenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swells and ache, traumatic injury, heat is gone into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.(the 647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Pericarpium Citri Reticulatae property of medicine suffering, hardship, temperature.Return spleen, stomach, lung meridian.Having in the accent of regulating the flow of vital energy stopping nausea and vomiting by lowering the adverse flow of QI, the effect of drying dampness to eliminate phlegm.It is full vexed to treat chest and diaphragm, abdominal distention, anorexia, vomiting, hiccup; Cough with copious phlegm.Acute mastitis from the beginning of etc.(the 1668th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Paeoniae Rubra property of medicine hardship is slightly cold.Return liver, spleen channel.Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, the carbuncle skin infection, amenorrhea, dysmenorrhea, the metrorrhagia and leukorrhagia stranguria with turbid discharge, the stasis of blood hypochondriac pain that stagnates, the hernia abdominal mass is gathered, injury from falling down etc.(the 1440th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Scrophulariae property of medicine is sweet, bitter, salty, is slightly cold.Return lung, stomach, kidney channel.Has removing heat from blood, nourishing YIN to lower pathogenic fire, antidotal effect.Can treat the warm febrile disease blood of joining the army, fever of the body, excessive thirst, crimson tongue is sent out speckle, the hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency is insomnia, and constipation is hindered in Tianjin, and order is puckery dim-sighted, laryngopharynx swelling and pain, tuberculous lymphadenitis, skin sore etc.(the 1062nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma sparganic nature and flavor suffering, hardship, flat.Return liver, spleen channel.Has removing blood stasis, circulation of qi promoting, removing food stagnancy analgesic effect.Can treat lump in the abdomen, coagulation of QI-blood, trusted subordinate's pain, the food stagnation distending pain, the side of body expands down painful, amenorrhea, dysmenorrhea, puerperal abdominalgia with blood stasis, traumatic injury, skin ulcer is swollen hard, hepatosplenomegaly etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 69th page).
Rhizoma Curcumae nature and flavor hardship, suffering, temperature.Return liver, spleen channel.Have the circulation of qi promoting removing blood stasis with potent drugs, the removing food stagnancy pain relieving is changed poly-eliminating mass, the effect of antiearly pregnancy.Can treat that trusted subordinate's distending pain, lump in the abdomen, dyspepsia do not disappear, hepatosplenomegaly, abdominal pain due to blood stasis, amenorrhea due to stagnation of blood, cervical erosion, traumatic injury have a pain etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 995th page).
Semen Persicae property of medicine hardship, sweet, mild toxicity.GUIXIN, liver, large intestine channel.Has blood circulation promoting and blood stasis dispelling, the effect of loosening bowel to relieve constipation.Can treat dysmenorrhea, amenorrhea due to stagnation of blood, the stagnant stomachache of the stasis of blood in puerperal , mass in the abdomen caking, traumatic injury, swelling and pain due to blood stasis, lung abscess, acute appendicitis, dryness of the intestine constipation etc.(the 2542nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Flos Carthami property of medicine suffering, temperature.GUIXIN, Liver Channel.Has promoting blood circulation to restore menstrual flow, the effect of stasis-dispelling and pain-killing.Can treat the blood stasis amenorrhea, dysmenorrhea, postpartum stagnation stomachache, obstruction of qi in the chest and cardialgia , mass in the abdomen knot is poly-, traumatic injury, arthralgia, apoplectic hemiplegia, macule etc.(the 2763rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Moutan property of medicine hardship, suffering are slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.Can treat the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, carbuncle sore tumefacting virus falls and pounces on the pain of injury, rheumatic arthralgia etc.(the 1578th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Vaccariae property of medicine hardship, flat.Return liver, stomach warp.Has promoting blood circulation to restore menstrual flow, the effect of stimulating milk secretion eliminating carbuncle.Can treat women's abdominal pain during menstruation, amenorrhea, galactostasis, acute mastitis, carbuncle etc.(the 426th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Aurantii property of medicine hardship, acid are slightly cold.Return lung, spleen, stomach, large intestine channel.Has the chest stuffiness relieving of regulating the flow of vital energy, the effect of the stagnant removing food stagnancy of row.Can treat the septum pectorale feeling of fullness, distending pain over the hypochondrium, accumulation of food in the stomach and intes tine due to indigestion, distension and fullness in the abdomen, heavy behind the dysentery, proctoptosis, uterine prolapse etc.(the 2227th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Pinelliae Preparatum property of medicine suffering, temperature, poisonous.Return spleen, stomach, lung meridian.Has drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the effect of dissolving lump and resolving mass.Can treat the cough with asthma abundant expectoration, vomiting regurgitation, feeling of oppression and fullness in the chest and epigastrium, pain is dizzy, uneasy sleeping at night, goiter sucutaneous nodule, swollen ulcer drug etc.(the 1073rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with rhizoma sparganic, Rhizoma Curcumae and Radix Salviae Miltiorrhizae; With Semen Persicae, Flos Carthami, Pericarpium Citri Reticulatae, Radix Paeoniae Rubra, Radix Scrophulariae and Rhizoma Pinelliae Preparatum is ministerial drug; With Cortex Moutan, Semen Vaccariae and Fructus Aurantii is adjuvant.All medicines are harmonious, and are total to the tool blood circulation promoting and blood stasis dispelling, the effect of promoting QI to circulate and dispersing the agglomeration of the pathogens.The treatment keloid has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment keloid of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat keloid, and the prevention of keloid is also had good effect, and the treatment keloid has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment keloid; Treatment keloid patient 20 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.9 examples of fully recovering account for 45%, and 9 examples that take a turn for the better account for 45%, and more 2 examples do not account for 10%, and total effective rate reaches 90%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction is pressed following weight weighting raw materials:
1 part of 1 part of Cortex Moutan of 3 parts of rhizoma sparganic of Radix Salviae Miltiorrhizae
1 part of 1 part of Semen Vaccariae of 2 parts of Rhizoma Curcumae of Pericarpium Citri Reticulatae
1 part of 1 part of Fructus Aurantii of 2 parts of Semen Persicaes of Radix Paeoniae Rubra
0.5 part of 1 part of Rhizoma Pinelliae Preparatum of 2 parts of Flos Carthamis of Radix Scrophulariae.
Preparation method is to get the above-mentioned raw materials medicine to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment keloid that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1. Chinese medicine preparation for the treatment of keloid is characterized in that it is made by following raw materials by weight proportions:
0.1~2 part of 0.1~2 part of Cortex Moutan of 1.5~6 parts of rhizoma sparganic of Radix Salviae Miltiorrhizae
0.1~2 part of 0.1~2 part of Semen Vaccariae of 1.0~4 parts of Rhizoma Curcumae of Pericarpium Citri Reticulatae
0.1~2 part of 0.1~2 part of Fructus Aurantii of 1.0~4 parts of Semen Persicaes of Radix Paeoniae Rubra
0.1~1 part of 0.1~2 part of Rhizoma Pinelliae Preparatum of 1.0~4 parts of Flos Carthamis of Radix Scrophulariae.
2. a kind of Chinese medicine preparation for the treatment of keloid according to claim 1, wherein the weight proportion of each crude drug is:
0.5~1.5 part of 0.5~1.5 part of Cortex Moutan of 2.5~3.5 parts of rhizoma sparganic of Radix Salviae Miltiorrhizae
0.5~1.5 part of 0.5~1.5 part of Semen Vaccariae of 1.5~2.5 parts of Rhizoma Curcumae of Pericarpium Citri Reticulatae
0.5~1.5 part of 0.5~1.5 part of Fructus Aurantii of 1.5~2.5 parts of Semen Persicaes of Radix Paeoniae Rubra
0.3~0.7 part of 0.5~1.5 part of Rhizoma Pinelliae Preparatum of 1.5~2.5 parts of Flos Carthamis of Radix Scrophulariae.
3. a kind of Chinese medicine preparation for the treatment of keloid according to claim 1, wherein the weight proportion of each crude drug is:
1 part of 1 part of Cortex Moutan of 3 parts of rhizoma sparganic of Radix Salviae Miltiorrhizae
1 part of 1 part of Semen Vaccariae of 2 parts of Rhizoma Curcumae of Pericarpium Citri Reticulatae
1 part of 1 part of Fructus Aurantii of 2 parts of Semen Persicaes of Radix Paeoniae Rubra
0.5 part of 1 part of Rhizoma Pinelliae Preparatum of 2 parts of Flos Carthamis of Radix Scrophulariae.
CNA2007101209156A 2007-08-29 2007-08-29 Chinese traditional medicine preparations for treating cheloid Pending CN101112572A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102512618A (en) * 2012-01-10 2012-06-27 隋玉兰 Medicament for treating cicatrices

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102512618A (en) * 2012-01-10 2012-06-27 隋玉兰 Medicament for treating cicatrices
CN102512618B (en) * 2012-01-10 2013-03-27 隋玉兰 Medicament for treating cicatrices

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Open date: 20080130