CN101071115B - Erythritol production method - Google Patents
Erythritol production method Download PDFInfo
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- CN101071115B CN101071115B CN 200710014929 CN200710014929A CN101071115B CN 101071115 B CN101071115 B CN 101071115B CN 200710014929 CN200710014929 CN 200710014929 CN 200710014929 A CN200710014929 A CN 200710014929A CN 101071115 B CN101071115 B CN 101071115B
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- CN
- China
- Prior art keywords
- antierythrite
- conductivity
- product
- feed liquid
- erythritol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 title claims abstract description 47
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 title claims abstract description 45
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 10
- 239000004386 Erythritol Substances 0.000 title abstract 6
- 229940009714 erythritol Drugs 0.000 title abstract 6
- 235000019414 erythritol Nutrition 0.000 title abstract 6
- 238000000034 method Methods 0.000 claims abstract description 26
- 239000007788 liquid Substances 0.000 claims abstract description 22
- 238000000855 fermentation Methods 0.000 claims abstract description 12
- 230000004151 fermentation Effects 0.000 claims abstract description 12
- 239000007864 aqueous solution Substances 0.000 claims abstract description 9
- 239000011347 resin Substances 0.000 claims abstract description 5
- 229920005989 resin Polymers 0.000 claims abstract description 5
- 238000001914 filtration Methods 0.000 claims abstract 2
- 238000002425 crystallisation Methods 0.000 claims description 4
- 230000008025 crystallization Effects 0.000 claims description 4
- 238000012856 packing Methods 0.000 claims description 4
- 235000014666 liquid concentrate Nutrition 0.000 claims 1
- 239000000463 material Substances 0.000 abstract 3
- 238000000502 dialysis Methods 0.000 abstract 2
- 150000001450 anions Chemical class 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 238000012797 qualification Methods 0.000 abstract 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 238000005374 membrane filtration Methods 0.000 description 2
- 238000003908 quality control method Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 150000005846 sugar alcohols Chemical class 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- JVWLUVNSQYXYBE-UHFFFAOYSA-N Ribitol Natural products OCC(C)C(O)C(O)CO JVWLUVNSQYXYBE-UHFFFAOYSA-N 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 235000009754 Vitis X bourquina Nutrition 0.000 description 1
- 235000012333 Vitis X labruscana Nutrition 0.000 description 1
- 240000006365 Vitis vinifera Species 0.000 description 1
- 235000014787 Vitis vinifera Nutrition 0.000 description 1
- -1 acyclic butanols Chemical class 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 235000013351 cheese Nutrition 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 235000021107 fermented food Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 238000011059 hazard and critical control points analysis Methods 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
- 230000007269 microbial metabolism Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- HEBKCHPVOIAQTA-ZXFHETKHSA-N ribitol Chemical compound OC[C@H](O)[C@H](O)[C@H](O)CO HEBKCHPVOIAQTA-ZXFHETKHSA-N 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 235000015067 sauces Nutrition 0.000 description 1
- 210000000697 sensory organ Anatomy 0.000 description 1
- 230000008786 sensory perception of smell Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 235000013555 soy sauce Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 150000003538 tetroses Chemical class 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Seasonings (AREA)
Abstract
This invention discloses a production method of erythritol, characterized in that a dialysis liquid is obtained after filtration and decoloration of an erythritol fermentation liquid, an erythritol process material liquid is obtained after anion and cation resin exchange treatment of the dialysis liquid, the conductivity of the process material liquid is less than or equal to 100mus/cm, and finally obtained the conductivity of the 0.1%-50% of the erythritol aqueous solution is less than or equal to 10.0mus/cm. The issue of odor is solved by controlling the material liquid conductivity in the process of extracting erythritol, and the qualification of products is achieved.
Description
Technical field
The invention belongs to the acyclic butanols technical field that contains hydroxyl, be specifically related to the production method of antierythrite (1,2,3,4-butantetraol).
Background technology
Antierythrite (1,2,3,4-butantetraol) is the sweet substance that tetrose alcohol has sucrose sweetness about 75%.It is present in fermented foods such as soy sauce, sauce class, grape wine, cheese.The suitability for industrialized production of antierythrite mainly is to adopt fermentation method now.Fermentation method is to be raw material with the starch hydrolyzation of glucose, produces accessory substances such as antierythrite and a spot of ribitol, glycerine through the osmophilic yeast strain fermentation, through separating, extract, refiningly obtaining highly purified antierythrite product.Roll up the 4th phase P63,64 " antierythrite Study on Fermentation " (Yang Xiaowei " biotechnology " August the 15th in 2005, Wu Yan etc.), the Chinese patent of CN1335391A, CN1369549A, CN1629299A, CN1932002A all relates to and adopts fermentation method to prepare antierythrite, its disclosed content quotation is in this.
Antierythrite microbial metabolism meeting in fermentation production process produces gas and has peculiar smell, if control is improper in follow-up product leaching process, can cause finished product to have certain peculiar smell, the moment peculiar smell of opening again after the packing of product is fairly obvious, under the form that the client requires the product increasingly stringent, influence quality and the sale of product.Therefore, seek the effective ways that a kind of stable control solves product odour, become the key that solves product quality.
The smell of in the past judging the antierythrite final products mainly relies on people's sense organ sense of smell that product is judged, there be very big subjective randomness and instability, in addition, from GMP, HACCP angle, also need to control by quality Control during Production the quality of final products.
Summary of the invention
The present invention is directed to problems of the prior art, extract the conductivity of feed liquid before the crystallization by controlling the back, thoroughly solved the smell problem of final products, stable provide up-to-standard antierythrite product for the client; But whether the smell of the control final products of the conductivity stable science by detecting the final products aqueous solution is qualified.
The present invention is achieved in that a kind of production method of antierythrite, it is characterized in that, controls its smell index by the conductivity of control antierythrite product aqueous solution.
The applicant is by evidence, and concentration is the conductivity≤10.0 μ s/cm of 0.1%-50% antierythrite aqueous solution, antierythrite product free from extraneous odour.
The present invention is by the control of control production run, realize the purpose of control final products smell index, specifically: the antierythrite fermentation liquor obtains dislysate after decolouring, dislysate obtains antierythrite process feed liquid after handling through the yin and yang resin exchange column again, and process feed liquid conductivity is less than 100 μ m/cm.More concrete scheme of the present invention is: the antierythrite fermentation liquor obtains dislysate after membrane filtration is handled, dislysate obtains antierythrite process feed liquid after handling through the yin and yang resin exchange column again, analytic process feed liquid conductivity is qualified, the antierythrite product that concentrate then, crystallization, centrifugal, oven dry, packing obtains free from extraneous odour.
Principle of the present invention is to utilize the impurity of control conductivity control procedure feed liquid, final products, and through applicant's evidence, the concentration of antierythrite is little to the conductivity influence of journey feed liquid and antierythrite aqueous solution.
The quality standard of prior art antierythrite is:
Compare with the method for quality control of prior art, the present invention has following beneficial effect:
1) the present invention controls the conductivity of final products by the conductivity of control pilot process feed liquid, and the control final products smell index that can stablize as one is qualified;
2) the present invention controls the conductivity of antierythrite aqueous solution, and quality index is quantized, and is conducive to further improve product quality;
3) conductivity of pilot process feed liquid of the present invention can be implemented in line traffic control.
Embodiment
Embodiment 1
Antierythrite fermentation liquor 35m
3, sugar alcohol concentration is 15.6%, carries out separation and sterilization through membrane filtration and obtains 36m
3Dislysate, sugar alcohol concentration are 15.1%, then through concentrating to such an extent that the concentrate volume is 8m
3Through the negative resin exchange column, remove smell in the feed liquid through positive resin-column again after, recording process feed liquid conductivity is 25.5 μ s/cm, carries out 3.36 tons of operation antierythrite products such as crystallization, centrifugal, oven dry, packing again.Product is carried out sampling Detection, 20 gram antierythrite products are dissolved in the 100ml deionized water, detecting antierythrite finished product aqueous solution conductivity is 1.9 μ s/cm, and product is the smell specification product.
Embodiment 2-10
According to the conductivity of following table control procedure feed liquid and final products, all the other are with embodiment 1.
| Embodiment | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 |
| The process feed concentration, % | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 |
| Process feed liquid conductivity, | 10 | 15 | 20 | 30 | 50 | 60 | 70 | 90 | 100 |
| Antierythrite finished product concentration, % | 0.1 | 0.5 | 1 | 10 | 15 | 20 | 30 | 40 | 50 |
| Antierythrite finished product conductivity, μ s/cm | 1.0 | 2.0 | 3.0 | 4.0 | 5.0 | 6.0 | 7.0 | 9.0 | 10.0 |
The above embodiments of the present invention are can not limit the present invention to explanation of the present invention, in the implication suitable with claims of the present invention and any change and the combination in the scope, all should think in the scope of claims.
Comparative Examples
Prepare antierythrite according to the method for implementing 1, process feed liquid conductivity after the exchange of process zwitterion is greater than 100 μ s/cm, if continue to separate purification according to the method for implementing 1, the antierythrite product that then makes has the peculiar smell of strong fermentation, and the smell index is defective.Detect the conductivity of finished product, 20% antierythrite finished product aqueous solution conductivity is 10.5 μ s/cm.
Claims (1)
1. the production method of an antierythrite, it is characterized in that, the antierythrite fermentation liquor obtains dislysate after decolouring after filtration, dislysate obtains antierythrite process feed liquid after exchange is handled through yin and yang resin again, described process feed liquid conductivity≤100 μ s/cm, the process feed liquid concentrates, crystallization, centrifugal, oven dry, packing obtain the antierythrite product, when concentration is the conductivity≤10.0 μ s/cm of 0.1%-50% antierythrite product aqueous solution, and described antierythrite product free from extraneous odour.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200710014929 CN101071115B (en) | 2007-06-15 | 2007-06-15 | Erythritol production method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200710014929 CN101071115B (en) | 2007-06-15 | 2007-06-15 | Erythritol production method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101071115A CN101071115A (en) | 2007-11-14 |
| CN101071115B true CN101071115B (en) | 2013-07-03 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200710014929 Expired - Fee Related CN101071115B (en) | 2007-06-15 | 2007-06-15 | Erythritol production method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101071115B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105861570B (en) * | 2016-04-19 | 2019-05-03 | 齐鲁工业大学 | A kind of production method of odorless antierythrite |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1335391A (en) * | 2000-07-21 | 2002-02-13 | 食品工业发展研究所 | Saccharomycetes strain for producing erythritol |
| CN1629299A (en) * | 2004-10-12 | 2005-06-22 | 山东保龄宝生物技术有限公司 | Process for preparing Erythritol through fermentation |
| CN1932002A (en) * | 2005-09-14 | 2007-03-21 | 中国食品发酵工业研究院 | Candida lipolytica and the erythritol producing process therewith |
-
2007
- 2007-06-15 CN CN 200710014929 patent/CN101071115B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1335391A (en) * | 2000-07-21 | 2002-02-13 | 食品工业发展研究所 | Saccharomycetes strain for producing erythritol |
| CN1629299A (en) * | 2004-10-12 | 2005-06-22 | 山东保龄宝生物技术有限公司 | Process for preparing Erythritol through fermentation |
| CN1932002A (en) * | 2005-09-14 | 2007-03-21 | 中国食品发酵工业研究院 | Candida lipolytica and the erythritol producing process therewith |
Non-Patent Citations (3)
| Title |
|---|
| JP特开2003-279516A 2003.10.02 |
| 发酵法生产无热量的赤藓糖醇及其特性和应用;金其荣等;《中国食品添加剂协会成立十周年暨第七届中国国际食品添加剂展览会学术论文集》;20031231;199-201 * |
| 金其荣等.发酵法生产无热量的赤藓糖醇及其特性和应用.《中国食品添加剂协会成立十周年暨第七届中国国际食品添加剂展览会学术论文集》.2003,199-201. |
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| Publication number | Publication date |
|---|---|
| CN101071115A (en) | 2007-11-14 |
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Address after: 255120 No. 18 Zhai Lu, Zichuan District, Shandong, Zibo Applicant after: ZIBO ZHONGSHUN BIOTECH Co.,Ltd. Address before: 255120 No. 18 Zhai Lu, Zichuan District, Shandong, Zibo Applicant before: Zibo Sino Shun Real Estate Co.,Ltd. |
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Denomination of invention: Production method of erythritol Effective date of registration: 20170206 Granted publication date: 20130703 Pledgee: Zichuan Zibo rural commercial bank Limited by Share Ltd. Pledgor: Zibo Zhongshi Green Biotech Co.,Ltd. Registration number: 2017370000013 |
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Date of cancellation: 20170214 Granted publication date: 20130703 Pledgee: Zichuan Zibo rural commercial bank Limited by Share Ltd. Pledgor: Zibo Zhongshi Green Biotech Co.,Ltd. Registration number: 2017370000013 |
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Denomination of invention: Production method of erythritol Effective date of registration: 20170216 Granted publication date: 20130703 Pledgee: Zichuan Zibo rural commercial bank Limited by Share Ltd. Pledgor: Zibo Zhongshi Green Biotech Co.,Ltd. Registration number: 2017370000017 |
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Denomination of invention: Production method of erythritol Effective date of registration: 20180523 Granted publication date: 20130703 Pledgee: Zichuan Zibo rural commercial bank Limited by Share Ltd. Pledgor: Zibo Zhongshi Green Biotech Co.,Ltd. Registration number: 2018370000093 |
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