CN101068830B - 蛋白质过敏原衍生物 - Google Patents

蛋白质过敏原衍生物 Download PDF

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Publication number
CN101068830B
CN101068830B CN2005800416270A CN200580041627A CN101068830B CN 101068830 B CN101068830 B CN 101068830B CN 2005800416270 A CN2005800416270 A CN 2005800416270A CN 200580041627 A CN200580041627 A CN 200580041627A CN 101068830 B CN101068830 B CN 101068830B
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CN
China
Prior art keywords
allergens
allergen
rder
wild
derivative
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Expired - Fee Related
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CN2005800416270A
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English (en)
Chinese (zh)
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CN101068830A (zh
Inventor
K·韦斯特恩
M·弗克
P·瓦朗
W·凯勒
R·瓦伦察
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Biomay AG
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Biomay AG
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36202602&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN101068830(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biomay AG filed Critical Biomay AG
Publication of CN101068830A publication Critical patent/CN101068830A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN2005800416270A 2004-12-02 2005-12-02 蛋白质过敏原衍生物 Expired - Fee Related CN101068830B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT0202804A AT501101B1 (de) 2004-12-02 2004-12-02 Protein-allergen-derivat
ATA2028/2004 2004-12-02
PCT/AT2005/000486 WO2006058359A2 (en) 2004-12-02 2005-12-02 Protein allergen derivatives

Publications (2)

Publication Number Publication Date
CN101068830A CN101068830A (zh) 2007-11-07
CN101068830B true CN101068830B (zh) 2012-05-09

Family

ID=36202602

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2005800416270A Expired - Fee Related CN101068830B (zh) 2004-12-02 2005-12-02 蛋白质过敏原衍生物

Country Status (11)

Country Link
US (1) US20080286311A1 (enExample)
EP (1) EP1817330B1 (enExample)
JP (1) JP2008521837A (enExample)
CN (1) CN101068830B (enExample)
AT (2) AT501101B1 (enExample)
AU (1) AU2005312324B2 (enExample)
CA (1) CA2589187A1 (enExample)
DE (1) DE602005011667D1 (enExample)
ES (1) ES2319218T3 (enExample)
PL (1) PL1817330T3 (enExample)
WO (1) WO2006058359A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8709435B2 (en) 2003-01-21 2014-04-29 Biomay Ag Hypallergenic mosaic antigens and methods of making same
ES2307381B1 (es) * 2006-04-12 2009-10-23 Bial Industrial Farmaceutica S.A. Proteinas quimericas hipoalergenicas pertenecientes a la familia de transportadoras de lipidos de parietaria judaica utiles para el tratami ento de alergias.
AT503690A1 (de) * 2006-06-09 2007-12-15 Biomay Ag Hypoallergene moleküle
EP1872792A1 (en) * 2006-06-29 2008-01-02 Biotech Tools S.A. A method for the production of hydrolyzed allergen
ES2638308T3 (es) * 2008-03-25 2017-10-19 Bial Industrial Farmaceutica, S.A. Proteínas híbridas hipoalergénicas de alérgenos de ácaros del grupo 1 y 2 principales para uso en el tratamiento de alergias
EP2110383A1 (en) 2008-04-14 2009-10-21 Biomay AG Hypoallergenic variants
EP2295076A1 (en) 2009-09-10 2011-03-16 Biomay Ag Hypoallergenic hybrid polypeptides for the treatment of allergy
CA2870399A1 (en) * 2012-04-16 2013-10-24 Alk-Abello A/S Plant profilin polypeptides for use in non-specific allergy immunotherapy
CN110055340B (zh) * 2019-04-11 2021-01-01 中国农业大学 一种食品中牛源成分快速检测方法及试剂盒
CN113173982B (zh) * 2021-04-14 2022-09-06 中国海洋大学 Rap v 2蛋白相关的抗原表位肽及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0765936A1 (en) * 1987-06-17 1997-04-02 Institute For Child Health Research Cloning of mite allergens
US5433948A (en) * 1990-02-13 1995-07-18 Thomas; Wayne R. Cloning and sequencing of allergens of dermatophagoides (house dust mite)
CA2066801A1 (en) * 1991-04-26 1992-10-27 Shyam S Mohapatra Determination of dna sequences of a novel group of major grass pollen allergens and the synthesis of their correspsonding recombinant proteins
JPH1075783A (ja) * 1996-09-04 1998-03-24 Fumakilla Ltd 組換えダニアレルゲン
JP2001231563A (ja) * 2000-02-18 2001-08-28 Asahi Breweries Ltd 改変したダニアレルゲン（システイン変異体）及びその製造方法
US7265208B2 (en) * 2001-05-01 2007-09-04 The Regents Of The University Of California Fusion molecules and treatment of IgE-mediated allergic diseases
US7279295B2 (en) * 2002-03-27 2007-10-09 Phadia Ab Allergen
PT1403280E (pt) * 2002-09-27 2005-11-30 Biomay Prod & Handel Vacinas hipoalergenicas baseadas no alergenio ph1 p 7 de polen de capim timoteo
WO2004039834A2 (en) * 2002-11-01 2004-05-13 Alk-Abelló A/S Recombinant protein variants
DE60301944T2 (de) * 2003-01-21 2006-06-01 Biomay Produktions- Und Handels-Aktiengesellschaft Verfahren zur Vorbereitung von hypoallergenen Mosaikproteinen#

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Kerstin Westritschnig and Rudolf Valenta.Can we genetically engineer safer and more effectiveimmunotherapy reagents?.Current opipion in allergy and clinical immunology3 6.2003,3(6),495-500.
Kerstin Westritschnig and Rudolf Valenta.Can we genetically engineer safer and more effectiveimmunotherapy reagents?.Current opipion in allergy and clinical immunology3 6.2003,3(6),495-500. *
Susanne Vrtala et al.Strategies for converting allergens into hypoallergenicvaccine candidates.Methods32 3.2004,32(3),313-320.
Susanne Vrtala et al.Strategies for converting allergens into hypoallergenicvaccine candidates.Methods32 3.2004,32(3),313-320. *

Also Published As

Publication number Publication date
PL1817330T3 (pl) 2009-06-30
WO2006058359A2 (en) 2006-06-08
ATE417060T1 (de) 2008-12-15
AT501101A1 (de) 2006-06-15
ES2319218T3 (es) 2009-05-05
CA2589187A1 (en) 2006-06-08
AU2005312324B2 (en) 2011-05-12
WO2006058359A3 (en) 2006-07-27
CN101068830A (zh) 2007-11-07
EP1817330A2 (en) 2007-08-15
AT501101B1 (de) 2008-01-15
EP1817330B1 (en) 2008-12-10
AU2005312324A1 (en) 2006-06-08
JP2008521837A (ja) 2008-06-26
US20080286311A1 (en) 2008-11-20
DE602005011667D1 (de) 2009-01-22

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CN101068830B (zh) 蛋白质过敏原衍生物
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Granted publication date: 20120509

Termination date: 20151202

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