CN101066416A - Medicine containing rabeprazole for treating gastric ulcer - Google Patents
Medicine containing rabeprazole for treating gastric ulcer Download PDFInfo
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- CN101066416A CN101066416A CNA2007101059888A CN200710105988A CN101066416A CN 101066416 A CN101066416 A CN 101066416A CN A2007101059888 A CNA2007101059888 A CN A2007101059888A CN 200710105988 A CN200710105988 A CN 200710105988A CN 101066416 A CN101066416 A CN 101066416A
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- medicine
- rhizoma
- chinese medicine
- gastric ulcer
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Abstract
The present invention discloses one kind of synergistic medicine composition containing rabeprazole and Chinese medicine extract, and the application of the medicine composition in preparing medicine for treating gastric ulcer.
Description
The present invention relates to a kind of medicine for the treatment of gastropathy, is the compositions of being made by Chinese crude drug extract and Western medicine, is particularly suitable for the medicine as treatment gastritis, peptic ulcer gastropathy such as (containing gastric ulcer and duodenal bulbar ulcer).
Gastropathy, particularly gastritis (shallow harmony in the exterior atrophic), peptic ulcer (containing gastric ulcer and duodenal bulbar ulcer) is a kind of commonly encountered diseases, frequently-occurring disease.At present, the medicine for the treatment of these diseases is more, the curative effect of the degree of having nothing in common with each other, but generally speaking, curative effect is not ideal enough, and relapse rate is higher after the drug withdrawal, and with regard to better medicine at present commonly used: its effective percentage is below 80%, and its relapse rate is more than 36%.
Purpose of the present invention just is: invent a kind of composition medicine of being made up of Chinese medicine extract and Western medicine for the treatment of gastric ulcer, to improve the treatment curative effect and to reduce relapse rate.
The present invention realizes its purpose like this: the present composition comprises Chinese medicine extract and Western medicine, and wherein Chinese medicine extract is prepared by following method:
Chinese medicine medical material component and proportional quantity thereof, % counts with percentage ratio:
Rhizoma Alpiniae Officinarum 4, the Radix Aucklandiae 3, Os Sepiae 3, Rhizoma Curcumae 10, Amomum globosum loureiro 1,
Radix Et Rhizoma Nardostachyos 6, dried Alumen 3, Endothelium Corneum Gigeriae Galli 3, Rhizoma Coptidis 3, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10,
Rhizoma Corydalis 11, Fructus Hordei Germinatus 1, Radix Aristolochiae 20, Semen Trichosanthis 2, Corium elephatis 20.
The summation of its each component is 100%.
Earlier Chinese crude drug is cleaned, press the proportional quantity metering, and the medicine village is concocted with conventional concocting method, powder is defended in pulverizing, decoct with water, and filtration, concentrated filtrate is to thick paste, drying.
Pharmaceutical composition Chinese medicine and western medicine of the present invention in addition is a rabeprazole, and the weight ratio of Chinese medicine extract and Western medicine is 53: 1.
Chinese medicine extract prescription in the pharmaceutical composition of the present invention is from the embodiment 1 of CN1055015C.
Pharmaceutical composition of the present invention can be made into various peroral dosage forms, and three times on the one, each 2 grams, seriously ill person's four times a day, boiled water is taken after mixing it with water.For gastritis (shallow table or atrophic), 7 is a course of treatment, serve on 2-3 the course of treatment, and for peptic ulcer (containing gastric ulcer and bulboduodenal ulcer), be a course of treatment January, serve on 2-3 the course of treatment.Taboo: dry peppery, the raw food food such as hard of fasting.
Clinical effectiveness:
To gastric ulcer 39 examples, treat 5 courses of treatment after.Through hospital's fiber microscopy and biopsy, 17 examples of wherein fully recovering, effective 19 examples, invalid 3 examples.Average total effective rate is 92.3%, and the toxic side effect reaction is found at the end.And with the pure Chinese medicine extract or the rabeprazole of Isodose, effective percentage is respectively 65% and 84%.
The treatment standard declaration: recovery from illness refers to after 2-3 the course of treatment 1 clinical symptom disappearance.Through fiber microscopy and biopsy, foci disappearance.Effectively refer to after 2～8 courses of treatment, through fiber microscopy and biopsy, clinical symptom disappearance, the lesion tissue scope is dwindled.Invalid finger is after 2-3 the course of treatment, and clinical symptoms does not have significant change before fiber microscopy and biopsy and treatment.
Pharmacology and resultant effect analysis.The Rhizoma Curcumae heat-clearing and toxic substances removing of this medicine with the same usefulness of Rhizoma Coptidis, strengthens heat-clearing toxin-expelling functions, Corium elephatis granulation promoting good medicine, and dried Alumen is held back skin ulcer, reuses poliosis, the same usefulness of three flavors, granulation promoting power is grand, and it is remarkable to hold back skin ulcer, promotes the lesion tissue reparation effectively, and well can end digestive tract hemorrhage preferably; Semen Trichosanthis a surname spleen helps circulation of qi promoting intestinal stasis relieving class efficacy of drugs such as Radix Et Rhizoma Nardostachyos more remarkable, has effectively promoted the recovery of gastric motility function, reuses Rhizoma Corydalis, Radix Aristolochiae, fast and effeciently pain relieving.Therefore, comprehensive compatibility, this Chinese patent medicine is heat-clearing and toxic substances removing effectively, and effectively gastric acid inhibitory secretion of rabeprazole.The Chinese medicine and western medicine binding energy fundamentally reaches therapeutic purposes.
Claims (2)
1 one kinds of compositionss for the treatment of gastric ulcer, said composition comprises Chinese medicine extract and Western medicine, and wherein Chinese medicine extract is prepared by following method:
Chinese medicine medical material component and proportional quantity thereof, % counts with percentage ratio:
Rhizoma Alpiniae Officinarum 4, the Radix Aucklandiae 3, Os Sepiae 3, Rhizoma Curcumae 10, Amomum globosum loureiro 1,
Radix Et Rhizoma Nardostachyos 6, dried Alumen 3, Endothelium Corneum Gigeriae Galli 3, Rhizoma Coptidis 3, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10,
Rhizoma Corydalis 11, Fructus Hordei Germinatus 1, Radix Aristolochiae 20, Semen Trichosanthis 2, Corium elephatis 20.
The summation of its each component is 100%,
Earlier Chinese crude drug is cleaned, press the proportional quantity metering, and the medicine village is concocted with conventional concocting method, powder is defended in pulverizing, decoct with water, and filtration, concentrated filtrate is to thick paste, drying;
Pharmaceutical composition Chinese medicine and western medicine of the present invention in addition is a rabeprazole, and the weight ratio of Chinese medicine extract and Western medicine is 53: 1.
The usefulness of 2 compositionss as claimed in claim 1 in the medicine of preparation treatment gastric ulcer is coated with.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2007101059888A CN100534516C (en) | 2007-06-05 | 2007-06-05 | Medicine containing rabeprazole for treating gastric ulcer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2007101059888A CN100534516C (en) | 2007-06-05 | 2007-06-05 | Medicine containing rabeprazole for treating gastric ulcer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101066416A true CN101066416A (en) | 2007-11-07 |
| CN100534516C CN100534516C (en) | 2009-09-02 |
Family
ID=38879198
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2007101059888A Expired - Fee Related CN100534516C (en) | 2007-06-05 | 2007-06-05 | Medicine containing rabeprazole for treating gastric ulcer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100534516C (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101810828A (en) * | 2010-04-15 | 2010-08-25 | 张大宇 | Combination medicament containing teprenone |
| CN101926958B (en) * | 2009-12-30 | 2011-12-21 | 宁波市鄞州福瑞达生物科技有限公司 | Chinese and Western medicine composition containing carbenoxolone sodium |
| CN106421082A (en) * | 2016-12-27 | 2017-02-22 | 郑州莉迪亚医药科技有限公司 | Medicine composition for treating gastric ulcer |
-
2007
- 2007-06-05 CN CNB2007101059888A patent/CN100534516C/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101926958B (en) * | 2009-12-30 | 2011-12-21 | 宁波市鄞州福瑞达生物科技有限公司 | Chinese and Western medicine composition containing carbenoxolone sodium |
| CN101810828A (en) * | 2010-04-15 | 2010-08-25 | 张大宇 | Combination medicament containing teprenone |
| CN106421082A (en) * | 2016-12-27 | 2017-02-22 | 郑州莉迪亚医药科技有限公司 | Medicine composition for treating gastric ulcer |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100534516C (en) | 2009-09-02 |
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| C57 | Notification of unclear or unknown address | ||
| DD01 | Delivery of document by public notice |
Addressee: Zhang Hongyu Document name: Written notice of preliminary examination of application for patent for invention |
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| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C57 | Notification of unclear or unknown address | ||
| DD01 | Delivery of document by public notice |
Addressee: Zhang Hongyu Document name: Notice of application for publication of patent for invention and entry into the substantive examination procedure |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20090902 Termination date: 20100605 |