CN106421082A - Medicine composition for treating gastric ulcer - Google Patents
Medicine composition for treating gastric ulcer Download PDFInfo
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- CN106421082A CN106421082A CN201611223291.6A CN201611223291A CN106421082A CN 106421082 A CN106421082 A CN 106421082A CN 201611223291 A CN201611223291 A CN 201611223291A CN 106421082 A CN106421082 A CN 106421082A
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- Prior art keywords
- gastric ulcer
- pharmaceutical composition
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- medicine composition
- active component
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a medicine composition for treating gastric ulcer. The active ingredients of the medicine composition comprises, by mass, 0.7-1.1 parts of houttuynia cordata extractive, 28-34 parts of rabeprazole and 2.5-3.0 parts of pemetrexed; dosage of administration for an adult is 0.54-0.60 mg active ingredients/kg/day. The medicine composition has functions of promoting qi circulation to relieve pain, invigorating spleen to promote digestion, tranquilizing mind by nourishing the heart, and promoting blood circulation and arresting bleeding, and the medicine composition has the advantages of being simple and convenient in preparation, remarkable and reliable in efficacy, short in course of treatment, and quick in result, and can be broadly applied and popularized clinically.
Description
Technical field
The present invention relates to Western medicine field, specifically a kind of pharmaceutical composition for treating gastric ulcer.
Background technology
Peptic Ulcerss or peptic ulcer are a kind of common digestive tract disease, can betide esophaguses, stomach or duodenum,
Stomach-intestinal anastomosis mouth can be betided nearby or in the diverticulum containing gastric mucosa, because gastric ulcer and duodenal ulcer are most common,
Therefore typically so-called peptic ulcer refers to gastric ulcer and duodenal ulcer.Epigastrium pain is the cardinal symptom of primary disease.Many
Positioned at epigastrium, after may also appear in left upper abdomen or breastbone, xiphoid-process.Often in dull pain, dull pain, distending pain, burn sample pain.Gastric ulcer
Pain many occurred in 1 hour after the meal, gradually alleviate after 1-2 hour, until reappearing the above-mentioned rhythm and pace of moving things again after lower meal feed.Portion
Point patient can be asymptomatic, or using complication such as bleeding, perforation as onset symptoms.After gastric ulcer, need to be treated in time,
Not so the complication such as upper gastrointestinal hemorrhage, perforated ulcer, pyloric obstruction can be caused, or even canceration can be caused.
The method of existing treatment gastric ulcer mainly includes pharmacotherapy and operative treatment.Drug therapy is more slow, effect
Very undesirable, medicine will be treated especially in pharmacotherapy based on Western medicine, Western medicine has side effect, and high recurrence rate；And perform the operation
There is great risk in treatment, while bringing pain to patient, also increased great economic pressures to patient.
Content of the invention
It is an object of the invention to provide a kind of low cost, drug effect significantly treat the pharmaceutical composition of gastric ulcer.
For achieving the above object, the present invention provides following technical scheme：
A kind of pharmaceutical composition for treating gastric ulcer, according to mass fraction meter, its active component is by Herba Houttuyniae extract
0.7-1.1 part, rabeprazole 28-34 part and pemetrexed 2.5-3.0 part composition.
As the further scheme of the present invention：According to mass fraction meter, its active component is by Herba Houttuyniae extract 0.8-1.0
Part, rabeprazole 30-32 part and pemetrexed 2.6-2.8 part composition.
As the further scheme of the present invention：According to mass fraction meter, its active component by 0.9 part of Herba Houttuyniae extract,
31 parts of rabeprazole and 2.7 parts of compositions of pemetrexed.
As the further scheme of the present invention：Adult's dosage of described pharmaceutical composition is lived for 0.54-0.60mg
Property composition/kg/ day.
As the further scheme of the present invention：Adult's dosage of described pharmaceutical composition becomes for 0.58mg activity
Point/kg/ day.
Purposes of the described pharmaceutical composition in treatment Gastric Ulcer Treatment is prepared.
Compared with prior art, the invention has the beneficial effects as follows：Pharmaceutical composition of the present invention has promoting the circulation of QI to relieve pain, spleen invigorating and disappears
The effects such as food, tranquilizing by nourishing the heart, promoting blood circulation and hemostasis, the treatment to gastric ulcer has configuration simplicity, drug effect notable reliability, short treating period, sees
The fast advantage of effect, extensively clinically can be applicable.
Specific embodiment
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described,
Obviously, described embodiment is only a part of embodiment of the present invention, rather than whole embodiments.Based in the present invention
Embodiment, the every other embodiment obtained under the premise of creative work is not made by those of ordinary skill in the art, all
Belong to the scope of protection of the invention.
Embodiment 1
In the embodiment of the present invention, a kind of pharmaceutical composition for treating gastric ulcer, according to mass fraction meter, its active component by
0.7 part of Herba Houttuyniae extract, 34 parts of rabeprazole and 2.5 parts of compositions of pemetrexed.
Embodiment 2
In the embodiment of the present invention, a kind of pharmaceutical composition for treating gastric ulcer, according to mass fraction meter, its active component by
1.1 parts of Herba Houttuyniae extract, 28 parts of rabeprazole and 3.0 parts of compositions of pemetrexed.
Embodiment 3
In the embodiment of the present invention, a kind of pharmaceutical composition for treating gastric ulcer, according to mass fraction meter, its active component by
0.8 part of Herba Houttuyniae extract, 32 parts of rabeprazole and 2.6 parts of compositions of pemetrexed.
Embodiment 4
In the embodiment of the present invention, a kind of pharmaceutical composition for treating gastric ulcer, according to mass fraction meter, its active component by
1.0 parts of Herba Houttuyniae extract, 30 parts of rabeprazole and 2.8 parts of compositions of pemetrexed.
Embodiment 5
In the embodiment of the present invention, a kind of pharmaceutical composition for treating gastric ulcer, according to mass fraction meter, its active component by
0.9 part of Herba Houttuyniae extract, 31 parts of rabeprazole and 2.7 parts of compositions of pemetrexed.
In above-described embodiment, the preparation process of the described pharmaceutical composition for treating gastric ulcer is：With Herba Houttuyniae extract,
Rabeprazole and pemetrexed are active component, using acceptable technique and adjuvant on pharmaceuticss, to make on various pharmaceuticss
Acceptable peroral dosage form.
The effects such as pharmaceutical composition of the present invention has promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion, tranquilizing by nourishing the heart, promoting blood circulation and hemostasis, bursts to stomach
The treatment of infectionss is have the advantages that configuration simplicity, drug effect notable reliability, short treating period, instant effect.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie
In the case of spirit or essential attributes without departing substantially from the present invention, the present invention can be realized in other specific forms.Therefore, no matter
From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power
Profit is required rather than described above is limited, it is intended that all in the implication and scope of the equivalency of claim by falling
Change is included in the present invention.
Moreover, it will be appreciated that although this specification is been described by according to embodiment, not each embodiment is only wrapped
Containing an independent technical scheme, this narrating mode of description is only that those skilled in the art should for clarity
Using description as an entirety, the technical scheme in each embodiment can also form those skilled in the art through appropriately combined
Understandable other embodiment.
Claims (6)
1. a kind of pharmaceutical composition for treating gastric ulcer, it is characterised in that according to mass fraction meter, its active component is by Herba Houttuyniae
Extract 0.7-1.1 part, rabeprazole 28-34 part and pemetrexed 2.5-3.0 part composition.
2. according to claim 1 treatment gastric ulcer pharmaceutical composition, it is characterised in that according to mass fraction meter, its
Active component is made up of Herba Houttuyniae extract 0.8-1.0 part, rabeprazole 30-32 part and pemetrexed 2.6-2.8 part.
3. according to claim 2 treatment gastric ulcer pharmaceutical composition, it is characterised in that according to mass fraction meter, its
Active component is made up of 0.9 part of Herba Houttuyniae extract, 31 parts of rabeprazole and 2.7 parts of pemetrexed.
4. according to the pharmaceutical composition of the arbitrary described treatment gastric ulcer of claim 1-3, it is characterised in that described medicine group
Adult's dosage of compound is 0.54-0.60mg active component/kg/ day.
5. according to claim 4 treatment gastric ulcer pharmaceutical composition, it is characterised in that described pharmaceutical composition
Adult's dosage is 0.58mg active component/kg/ day.
6. the purposes in treatment Gastric Ulcer Treatment is being prepared according to the arbitrary described pharmaceutical composition of claim 1-3.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611223291.6A CN106421082A (en) | 2016-12-27 | 2016-12-27 | Medicine composition for treating gastric ulcer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611223291.6A CN106421082A (en) | 2016-12-27 | 2016-12-27 | Medicine composition for treating gastric ulcer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106421082A true CN106421082A (en) | 2017-02-22 |
Family
ID=58215673
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611223291.6A Pending CN106421082A (en) | 2016-12-27 | 2016-12-27 | Medicine composition for treating gastric ulcer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106421082A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1480179A (en) * | 2003-07-21 | 2004-03-10 | 洪彰福 | Preparation of houttuynia for treating peptic ulcer as well as acute and chronic gastritis |
| CN1907284A (en) * | 2006-07-28 | 2007-02-07 | 南京依诺维医药科技有限公司 | Pharmaceutical composition containing pemetrexed |
| CN101066416A (en) * | 2007-06-05 | 2007-11-07 | 徐雪娟 | Medicine containing rabeprazole for treating gastric ulcer |
-
2016
- 2016-12-27 CN CN201611223291.6A patent/CN106421082A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1480179A (en) * | 2003-07-21 | 2004-03-10 | 洪彰福 | Preparation of houttuynia for treating peptic ulcer as well as acute and chronic gastritis |
| CN1907284A (en) * | 2006-07-28 | 2007-02-07 | 南京依诺维医药科技有限公司 | Pharmaceutical composition containing pemetrexed |
| CN101066416A (en) * | 2007-06-05 | 2007-11-07 | 徐雪娟 | Medicine containing rabeprazole for treating gastric ulcer |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170222 |
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| RJ01 | Rejection of invention patent application after publication |