CN101044247B - 用于鉴定,评估,预防和治疗子宫颈癌的组合物,试剂盒及方法 - Google Patents
用于鉴定,评估,预防和治疗子宫颈癌的组合物,试剂盒及方法 Download PDFInfo
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- CN101044247B CN101044247B CN03824456XA CN03824456A CN101044247B CN 101044247 B CN101044247 B CN 101044247B CN 03824456X A CN03824456X A CN 03824456XA CN 03824456 A CN03824456 A CN 03824456A CN 101044247 B CN101044247 B CN 101044247B
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57411—Specifically defined cancers of cervix
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Hospice & Palliative Care (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40477002P | 2002-08-20 | 2002-08-20 | |
| US60/404,770 | 2002-08-20 | ||
| PCT/US2003/026184 WO2004018999A2 (en) | 2002-08-20 | 2003-08-20 | Compositions, kits, and methods for identification, assessment, prevention, and therapy of cervical cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011101186127A Division CN102220423A (zh) | 2002-08-20 | 2003-08-20 | 用于鉴定,评估,预防和治疗子宫颈癌的组合物,试剂盒及方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101044247A CN101044247A (zh) | 2007-09-26 |
| CN101044247B true CN101044247B (zh) | 2011-06-22 |
Family
ID=31946760
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN03824456XA Expired - Fee Related CN101044247B (zh) | 2002-08-20 | 2003-08-20 | 用于鉴定,评估,预防和治疗子宫颈癌的组合物,试剂盒及方法 |
| CN2011101186127A Pending CN102220423A (zh) | 2002-08-20 | 2003-08-20 | 用于鉴定,评估,预防和治疗子宫颈癌的组合物,试剂盒及方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011101186127A Pending CN102220423A (zh) | 2002-08-20 | 2003-08-20 | 用于鉴定,评估,预防和治疗子宫颈癌的组合物,试剂盒及方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US7361511B2 (enExample) |
| EP (6) | EP2311978A1 (enExample) |
| JP (2) | JP2006514823A (enExample) |
| KR (1) | KR20050058407A (enExample) |
| CN (2) | CN101044247B (enExample) |
| AT (1) | ATE519862T1 (enExample) |
| AU (1) | AU2003265556A1 (enExample) |
| CA (1) | CA2496272A1 (enExample) |
| WO (1) | WO2004018999A2 (enExample) |
Families Citing this family (30)
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| US7579160B2 (en) | 1998-03-18 | 2009-08-25 | Corixa Corporation | Methods for the detection of cervical cancer |
| WO2002101075A2 (en) * | 2001-06-13 | 2002-12-19 | Millennium Pharmaceuticals, Inc. | Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of cervical cancer |
| US7482116B2 (en) | 2002-06-07 | 2009-01-27 | Dna Genotek Inc. | Compositions and methods for obtaining nucleic acids from sputum |
| KR20050058407A (ko) * | 2002-08-20 | 2005-06-16 | 밀레니엄 파머슈티컬스 인코퍼레이티드 | 자궁경부암의 확인, 평가, 예방 및 요법을 위한 조성물, 키트 및 방법 |
| AU2003278112A1 (en) * | 2002-10-18 | 2004-05-04 | Silence Therapeutics Ag | Factor involved in metastasis and uses thereof |
| DE602005009702D1 (de) * | 2004-07-16 | 2008-10-23 | Oncomethylome Sciences S A | Esr1 und gebärmutterhalskrebs |
| KR100939274B1 (ko) | 2004-08-16 | 2010-01-29 | 쿠아크 파마수티칼스 인코퍼레이티드 | 알티피801 억제제의 치료적 용도 |
| JP2009508493A (ja) | 2005-09-19 | 2009-03-05 | ベリデックス・エルエルシー | すい臓がんを診断するための方法 |
| AT502722B8 (de) * | 2005-10-31 | 2009-08-15 | Bmt Medizinische Forschung Und | Verwendung des interferon induzierten gens 12 (isg 12, ifi 27) zur modulation transkriptioneller aktivitäten von nuklearen rezeptoren |
| AU2006332806B2 (en) * | 2005-12-30 | 2012-03-15 | Ventana Medical Systems, Inc. | Na+, K+-ATPase expression in cervical dysplasia and cancer |
| NL2000439C2 (nl) | 2006-01-20 | 2009-03-16 | Quark Biotech | Therapeutische toepassingen van inhibitoren van RTP801. |
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| EP2137205A2 (en) | 2007-02-26 | 2009-12-30 | Quark Pharmaceuticals, Inc. | Inhibitors of rtp801 and their use in disease treatment |
| US8614311B2 (en) | 2007-12-12 | 2013-12-24 | Quark Pharmaceuticals, Inc. | RTP801L siRNA compounds and methods of use thereof |
| JP5526378B2 (ja) * | 2009-03-05 | 2014-06-18 | 国立大学法人山口大学 | 子宮頸癌の検出方法 |
| KR20120034593A (ko) * | 2009-03-09 | 2012-04-12 | 유니버시티 오브 조지아 리서치 파운데이션 인코퍼레이티드 | 위암 진단용 단백질 마커의 동정 |
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| WO2012161670A2 (en) | 2010-04-07 | 2012-11-29 | Incube Labs, Llc | Method for treating diabetes and other glucose regulation disorders using stem cells |
| CN102372773B (zh) | 2010-08-11 | 2013-06-05 | 中国科学院生物物理研究所 | 人膀胱癌肿瘤标志物及其抗体和应用 |
| MX347611B (es) | 2011-06-19 | 2017-05-04 | Abogen Inc | Dispositivos, soluciones y metodos para recoleccion de muestras. |
| US9804160B2 (en) | 2011-09-28 | 2017-10-31 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Protein-protein interaction as biomarkers |
| JP5876359B2 (ja) * | 2012-03-30 | 2016-03-02 | シスメックス株式会社 | 癌化情報提供方法および癌化情報提供装置 |
| US20160187341A1 (en) * | 2013-08-08 | 2016-06-30 | The Research Foundation For The State University Of New York | Keratins as biomarkers for cervical cancer and survival |
| CN114965989A (zh) | 2015-02-09 | 2022-08-30 | Dna吉诺特克股份有限公司 | 用于采集相关应用、分析和诊断的样本的设备、溶液和方法 |
| SG11201708360TA (en) * | 2015-04-13 | 2017-11-29 | Aduro Biotech Inc | Epidermal growth factor receptor variant iii-mesothelin fusions and methods of using the same |
| HK1250731A1 (zh) | 2015-04-13 | 2019-01-11 | 艾杜罗生物科技公司 | 用於治疗癌症的免疫原性融合蛋白 |
| US10487365B2 (en) | 2016-09-20 | 2019-11-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods for detecting expression of lnc-FANCI-2 in cervical cells |
| CN109198732A (zh) * | 2018-08-20 | 2019-01-15 | 苏州晞光生物科技有限公司 | 一种智能化可穿戴检测人体分泌物的服装及测试方法 |
| GB201820867D0 (en) * | 2018-12-20 | 2019-02-06 | Arquer Diagnostics Ltd | Detection method |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001042467A2 (en) * | 1999-12-08 | 2001-06-14 | Millennium Pharmaceuticals, Inc. | Genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of cervical cancer |
| WO2001042792A2 (en) * | 1999-12-08 | 2001-06-14 | Millennium Pharmaceuticals, Inc. | Diagnosis of cervical cancer using marker proteins |
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2003
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- 2003-08-20 CN CN03824456XA patent/CN101044247B/zh not_active Expired - Fee Related
- 2003-08-20 AU AU2003265556A patent/AU2003265556A1/en not_active Abandoned
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- 2003-08-20 AT AT03793217T patent/ATE519862T1/de not_active IP Right Cessation
- 2003-08-20 WO PCT/US2003/026184 patent/WO2004018999A2/en not_active Ceased
- 2003-08-20 EP EP10012249A patent/EP2311978A1/en not_active Withdrawn
- 2003-08-20 EP EP03793217A patent/EP1565581B1/en not_active Expired - Lifetime
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- 2003-08-20 EP EP10012317A patent/EP2314716A1/en not_active Withdrawn
- 2003-08-20 EP EP10012324A patent/EP2305836A1/en not_active Withdrawn
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- 2003-08-20 EP EP10012330A patent/EP2311980A1/en not_active Withdrawn
- 2003-08-20 JP JP2004529772A patent/JP2006514823A/ja active Pending
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2008
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2010
- 2010-08-16 JP JP2010181748A patent/JP2011036247A/ja active Pending
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- 2011-10-14 US US13/273,808 patent/US20120264625A1/en not_active Abandoned
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| WO2001042792A2 (en) * | 1999-12-08 | 2001-06-14 | Millennium Pharmaceuticals, Inc. | Diagnosis of cervical cancer using marker proteins |
Also Published As
| Publication number | Publication date |
|---|---|
| US20120264625A1 (en) | 2012-10-18 |
| CN102220423A (zh) | 2011-10-19 |
| AU2003265556A8 (en) | 2004-03-11 |
| WO2004018999A3 (en) | 2005-06-30 |
| EP1565581A2 (en) | 2005-08-24 |
| EP1565581B1 (en) | 2011-08-10 |
| JP2006514823A (ja) | 2006-05-18 |
| ATE519862T1 (de) | 2011-08-15 |
| KR20050058407A (ko) | 2005-06-16 |
| US20080286781A1 (en) | 2008-11-20 |
| EP2314716A1 (en) | 2011-04-27 |
| AU2003265556A1 (en) | 2004-03-11 |
| CN101044247A (zh) | 2007-09-26 |
| EP1565581A4 (en) | 2008-01-02 |
| US20050037010A1 (en) | 2005-02-17 |
| EP2311980A1 (en) | 2011-04-20 |
| EP2311979A1 (en) | 2011-04-20 |
| CA2496272A1 (en) | 2004-03-04 |
| WO2004018999A2 (en) | 2004-03-04 |
| EP2311978A1 (en) | 2011-04-20 |
| JP2011036247A (ja) | 2011-02-24 |
| US7361511B2 (en) | 2008-04-22 |
| EP2305836A1 (en) | 2011-04-06 |
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