CN101041015B - Medicine for treating hyperplasia of mammary glands - Google Patents
Medicine for treating hyperplasia of mammary glands Download PDFInfo
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- CN101041015B CN101041015B CN2007100720591A CN200710072059A CN101041015B CN 101041015 B CN101041015 B CN 101041015B CN 2007100720591 A CN2007100720591 A CN 2007100720591A CN 200710072059 A CN200710072059 A CN 200710072059A CN 101041015 B CN101041015 B CN 101041015B
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Abstract
The invention relates to a traditional Chinese medicinal composition for treating mammary gland hyperplasia, which is prepared from calculus bovis 15-20 parts, orpiment 5-10 parts, wasp's nest 20-40 parts, frank incense 10-30 parts, myrrh 10-30 parts, Sichuan fritillary bulb 10-30 parts, sea weed 15-30 parts, buthus martensi kirsch 10-30 parts, house lizard 10-30 parts, pangolin scales 10-30 parts, blister bug 1-5 parts, centipede 10-20 parts, bulb of edible tulip 10-30 parts, seed of cowherb 10-30 parts, wood louse 10-30 parts, secretio bufonis 0.5-2 parts, cinnabar 2-10 parts, deglued antler powder 10-30 parts and white mustard seed 5-10 parts.
Description
Technical field:
The present invention relates to a kind of Chinese medicine preparation.
Background technology:
" cyclomastopathy " disease is women's frequently-occurring disease, is the benign proliferative diseases of mammary gland tissue.This cyclomastopathy is generally at the one-sided of women or lump appears in the bilateral breast and with mastalgia, generally before menstrual onset or when unhappy, increase the weight of, through after alleviate or disappear, suffer from cyclomastopathy, though life is had not big harm, health brought have a strong impact on.The cyclomastopathy sickness rate accounts for women's at reproduction age about 40%, and accounts for all mastoticly 75%, is modal cystic hyperplasia of breast, and therefore, effective medicine of research cyclomastopathy is significant.Now, the drug main of treatment cyclomastopathy will reach other articles for use as GUIZHI FULING JIAONANG, RUPIXIAO, anti-hypertrophy sheet etc., the prescription of its treatment hyperplasia of mammary glands is loaded down with trivial details, processing inconvenience, DeGrain, low, the toxic side effect of cure rate, and recurs easily.
Summary of the invention:
The present invention be have when cyclomastopathy being treated in order to solve that prescription is loaded down with trivial details with existing medicine, processing inconvenience, DeGrain, low, the toxic side effect of cure rate, and the problem that recurs easily.Disappear newborn anti-tumor capsule according to ratio of weight and number by Calculus Bovis 15-20 part; Realgar 5-10 part; Nidus Vespae 20-40 part; Olibanum 10-30 part; Myrrha 10-30 part; Bulbus Fritillariae Cirrhosae 10-30 part; Sargassum 15-30 part; Scorpio 10-30 part; Gekko Swinhonis 10-30 part; Squama Manis (Squama Manis of the process of preparing Chinese medicine) 10-30 part; Mylabris 1-5 part; Scolopendra 10-20 part; Pseudobulbus cremastrae seu pleiones 10-30 part; Semen Vaccariae 10-30 part; Eupolyphaga Seu Steleophaga 10-30 part; Venenum Bufonis 0.5-2 part; Cinnabaris 2-10 part; Cornu Cervi Degelatinatum 10-30 part; Semen Sinapis Albae 5-10 part is made.Manufacture method of the present invention is: above medicine is broken into 100 purpose fine powders, and sieve back sterilization stirs and can take every heavy 0.25g after incapsulating.The present invention has that prescription is refining, easy to process, determined curative effect, cure rate height, the advantage that has no side effect.After adhering to taking 1～3 course of treatment (menstrual cycle is a course of treatment), effective percentage of the present invention is up to 96.7%, and cure rate reaches more than 80%, inefficiency 3.3%.The present invention also can be used for the treatment to mastadenoma and thyroid tumor except that curing the cyclomastopathy.
Medical material Calculus Bovis-function among the present invention cures mainly: clears away heart-fire, reduces phlegm, and function of gallbladder promoting, relieving convulsion, control the calentura coma, delirium, epilepsy is gone mad, and infantile convulsion is twitched, ulcerative gingivitis, larynx is swollen, aphtha of the mouth and tongue, carbuncle, furunculosis.
Realgar-function cures mainly: dispels the wind, and parasite killing, detoxifcation is controlled scabies, tinea alba, carbuncle, acute gangrenous stomatitis, herpes zoster, tetanus, snakeworm sting, bromhidrosis, ecthyma, asthma, sore throat ， Jing Epilepsy, hemorrhoid complicated by anal fistula.
Nidus Vespae-function cures mainly: dispel the wind counteracting toxic substances, parasite killing.Zhi Jing Epilepsy, migratory arthralgia, the urticaria pruritus, acute mastitis, furunculosis, scrofula, anal fistula, acute toothache, tinea capitis, honeybee stings swollen painful.
Olibanum-function cures mainly: regulating qi and activating blood, and analgesic therapy chases after poison, and control QI and blood and coagulate band, trusted subordinate's pain, the carbuncle skin ulcer swells and ache, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.
Myrrha-function cures mainly: the blood blood stasis removing that looses, subduing swelling and relieving pain is controlled and is fallen damage, incised wound, muscles and bones, all Tong ， of trusted subordinate mass in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye.
Bulbus Fritillariae Cirrhosae-function cures mainly: the lung moistening eliminating stagnation, relieving cough and resolving phlegm is controlled cough due to consumptive disease, the spitting of blood of spitting, ambition pent-up, consumptive lung disease, lung abscess, goiter, scrofula, sore throat, acute mastitis
Sargassum-function cures mainly: softening the hard mass, and expectorant, diuretic expels the heat-evil, and controls scrofula, and goiter is gathered, edema, beriberi, painful and swollen testis.
Scorpio-function cures mainly: the spasmolytic that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., antiinflammatory counteracting toxic substances, removing obstruction in the collateral to relieve pain.
Gekko Swinhonis-function cures mainly: dispels the wind, and arresting convulsion, eliminating stagnation, paralysis due to windstroke is controlled in detoxifcation, severe and migratory arthralgia pain, wind-phlegm Jing Epilepsy, scrofula, malignant boil.
Squama Manis-function cures mainly: the stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis, expel wind to dredge collateral.Be used for amenorrhea and mass in the abdomen, galactostasis, carbuncle sore tumefacting virus, arthralgia, numbness contracture.
Mylabris-function cures mainly: counteracting toxic substances, removing blood stasis.
Scolopendra-function cures mainly: dispel the wind arresting convulsion, counteracting toxic substances, eliminating stagnation.Control apoplexy ， Jing Epilepsy, tetanus, pertussis, scrofula, tuberculosis ， mass in the abdomen tumor piece, sore swollen toxin, tinea corporis, bald in vain, anal fistula is scalded.
Pseudobulbus cremastrae seu pleiones-function cures mainly: detumescence, and eliminating stagnation is reduced phlegm, detoxifcation, it is swollen to control the carbuncle furuncle, scrofula, sore throat swells and ache, Serpentis, worm, mad dog hinders.
Semen Vaccariae-function cures mainly: promoting the circulation of blood is stimulated the menstrual flow, and expedites the emergence of stimulating milk secretion, and skin ulcer is held back in detumescence, controls women's amenorrhea, galactostasis, and difficult labour, stranguria with blood, carbuncle, incised wound is hemorrhage.
Eupolyphaga Seu Steleophaga-function cures mainly: removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.Be used for the muscles and bones folding and hinder blood stasis amenorrhea ， mass in the abdomen mass in the abdomen.
Venenum Bufonis-function cures mainly: detoxifcation, detumescence, heart tonifying, pain relieving, treatment skin ulcer, carbuncle, carbuncle on the back, scrofula, chronic osteomyelitis, laryngopharynx swelling and pain, infantile malnutrition, heart failure, wind, carious pain.
Cinnabaris-function cures mainly: calm the nerves, the arresting convulsion, make eye bright, the detoxifcation, control demented, the palpitation with fear, vexed, the insomnia, dizzy, blurred vision, toxic swelling, skin infection, scabies.
Cornu Cervi Degelatinatum-function cures mainly: tonify deficiency, and supporing yang, control insufficiency of kidney-YANG, ache of the spinal column, Deficiency and coldness of spleen and stomach, anorexia and loose stool, deficiency-cold of uterus, bleeding not during menses
Semen Sinapis Albae-function cures mainly: the promoting the circulation of QI eliminating phlegm, and warming spleen and stomach for dispelling cold, removing obstruction in the collateral to relieve pain is controlled the phlegm retention cough with asthma, fullness and distention in the chest and hypochondrium pain, regurgitation vomiting, aphasia due to apoplexy, limbs arthralgia pain fiber crops, beriberi, carbuncle of yin nature, toxic swelling, treating swelling and pain by traumatic injury.
The specific embodiment:
The specific embodiment one: the newborn anti-tumor capsule that disappears in the present embodiment according to ratio of weight and number by 15-20 part Calculus Bovis; 5-10 part Realgar; 20-40 part Nidus Vespae; 10-30 part Olibanum; 10-30 part Myrrha; 10-30 part Bulbus Fritillariae Cirrhosae; 15-30 part Sargassum; 10-30 part Scorpio; 10-30 part Gekko Swinhonis; 10-30 part Squama Manis (Squama Manis of the process of preparing Chinese medicine); 1-5 part Mylabris; 10-20 part Scolopendra; 10-30 part Pseudobulbus cremastrae seu pleiones; 10-30 part Semen Vaccariae; 10-30 part Eupolyphaga Seu Steleophaga; 0.5-2 part Venenum Bufonis; 2-10 part Cinnabaris; 10-30 part Cornu Cervi Degelatinatum; 5-10 part Semen Sinapis Albae is made.The method for production of present embodiment is: will more than be broken into 100 purpose fine powders, sieve back sterilization, stirring incapsulates, and promptly obtains a kind of medicine for the treatment of mammary gland, every heavy 0.25g.
The specific embodiment two: the newborn anti-tumor capsule that disappears in the present embodiment according to ratio of weight and number by 15.5-19.5 part Calculus Bovis; 5.5-9.5 part Realgar; 22-38 part Nidus Vespae; 12-28 part Olibanum; 12-28 part Myrrha; 12-28 part Bulbus Fritillariae Cirrhosae; 16-29 part Sargassum; 12-28 part Scorpio; 12-28 part Gekko Swinhonis; 12-28 part Squama Manis (Squama Manis of the process of preparing Chinese medicine); 1.5-4.5 part Mylabris; 11-19 part Scolopendra; 12-28 part Pseudobulbus cremastrae seu pleiones; 12-28 part Semen Vaccariae; 12-28 part Eupolyphaga Seu Steleophaga; 0.6-1.9 part Venenum Bufonis; 2.5-9.5 part Cinnabaris; 12-28 part Cornu Cervi Degelatinatum; 5.5-9.5 a part Semen Sinapis Albae is made.The manufacture method of present embodiment is identical with the specific embodiment one.
The specific embodiment three: the newborn anti-tumor capsule that disappears in the present embodiment according to ratio of weight and number by 16-19 part Calculus Bovis; 6-9 part Realgar; 24-36 part Nidus Vespae; 14-26 part Olibanum; 14-26 part Myrrha; 14-26 part Bulbus Fritillariae Cirrhosae; 17-28 part Sargassum; 14-26 part Scorpio; 14-26 part Gekko Swinhonis; 14-26 part Squama Manis (Squama Manis of the process of preparing Chinese medicine); 1.8-4.3 part Mylabris; 12-18 part Scolopendra; 14-26 part Pseudobulbus cremastrae seu pleiones; 14-26 part Semen Vaccariae; 14-26 part Eupolyphaga Seu Steleophaga; 0.7-1.8 part Venenum Bufonis; 3-9 part Cinnabaris; 14-26 part Cornu Cervi Degelatinatum; 6-9 part Semen Sinapis Albae is made.The manufacture method of present embodiment is identical with the specific embodiment one.
The specific embodiment four: the newborn anti-tumor capsule that disappears in the present embodiment according to ratio of weight and number by 16.5-18.5 part Calculus Bovis; 6.5-8.5 part Realgar; 26-34 part Nidus Vespae; 16-24 part Olibanum; 16-24 part Myrrha; 16-24 part Bulbus Fritillariae Cirrhosae; 18-27 part Sargassum; 16-24 part Scorpio; 16-24 part Gekko Swinhonis; 16-24 part Squama Manis (Squama Manis of the process of preparing Chinese medicine); 2-4 part Mylabris; 13-16 part Scolopendra; 16-24 part Pseudobulbus cremastrae seu pleiones; 16-24 part Semen Vaccariae; 16-24 part Eupolyphaga Seu Steleophaga; 0.8-1.7 part Venenum Bufonis; 3.5-8.5 part Cinnabaris; 16-24 part Cornu Cervi Degelatinatum; 6.5-8.5 a part Semen Sinapis Albae is made.The manufacture method of present embodiment is identical with the specific embodiment one.
The specific embodiment five: the newborn anti-tumor capsule that disappears in the present embodiment according to ratio of weight and number by 17-18 part Calculus Bovis; 7-8 part Realgar; 28-32 part Nidus Vespae; 18-22 part Olibanum; 18-22 part Myrrha; 18-22 part Bulbus Fritillariae Cirrhosae; 20-25 part Sargassum; 18-22 part Scorpio; 18-22 part Gekko Swinhonis; 18-22 part Squama Manis (Squama Manis of the process of preparing Chinese medicine); 2.2-3.8 part Mylabris; 14-15 part Scolopendra; 18-22 part Pseudobulbus cremastrae seu pleiones; 18-22 part Semen Vaccariae; 18-22 part Eupolyphaga Seu Steleophaga; 1-1.5 part Venenum Bufonis; 4-8 part Cinnabaris; 18-22 part Cornu Cervi Degelatinatum; 7-8 part Semen Sinapis Albae is made.The manufacture method of present embodiment is identical with the specific embodiment one.
The specific embodiment six: the newborn anti-tumor capsule that disappears in the present embodiment is made by 17 parts of Calculus Boviss, 7 portions of Realgars, 30 parts of Nidus Vespaes, 20 parts of Olibanums, 20 parts of Myrrhas, 20 parts of Bulbus Fritillariae Cirrhosaes, 23 portions of Sargassums, 20 parts of Scorpio, 20 parts of Gekko Swinhonis, 20 parts of Squama Maniss (Squama Manis of the process of preparing Chinese medicine), 3 portions of Mylabris, 14 parts of Scolopendras, 20 parts of Pseudobulbus cremastrae seu pleiones, 20 parts of Semen Vaccariae, 20 parts of Eupolyphaga Seu Steleophagas, 1 part of Venenum Bufonis, 6 parts of Cinnabaris, 20 parts of Cornu Cervi Degelatinatums, 7 parts of Semen Sinapis Albaes according to ratio of weight and number.The manufacture method of present embodiment is identical with the specific embodiment one.
The pharmacodynamics summary:
Usage: the newborn anti-tumor capsule that disappears in the present embodiment is used for the treatment of cyclomastopathy, a twice-daily when taking, and each 2, a menstrual cycle is a course of treatment.
The criterion of curative effect is: cure: lump in breast dwindles gradually during the medication, is not had by little change again, eliminates lump in breast, distending pain of the breast at last completely without the person; Produce effects: lump in breast obviously dwindles, distending pain of the breast alleviates; Effectively: distending pain of the breast alleviates; Invalid: the lump in breast size does not change, distending pain of the breast does not subtract.
Table 1 is the clinical pharmacodynamics report of the newborn anti-tumor capsule for treating cyclomastopathy that disappears in the present embodiment.
30 examples are carried out the treatment of 1-3 the course of treatment 25～62 years old cyclomastopathy patient at the ages, and effective percentage is up to 96.7%, and cure rate is higher than 80%, and therapeutic effect is as shown in table 1, and wherein the state of an illness is diagnosed and accepted and believed the diagnosis that regular hospital provides.
Table 1
| Sequence number | Age | Sex | Disease or symptom | Use soft capsule (course of treatment) | Therapeutic effect |
| 1? | 25? | The woman | Cyclomastopathy | Two | Cure |
| 2? | 30? | The woman | Cyclomastopathy | Two | Cure |
| 29? | 40? | The woman | Cyclomastopathy | Three | Cure |
| 30? | 30? | The woman | Cyclomastopathy | Three | Cure |
Present embodiment treatment cyclomastopathy, effect is good, Bulbus Fritillariae Uninbracteatae, Pseudobulbus cremastrae seu pleiones hard masses softening and resolving in the side, Scorpio, Scolopendra detoxifcation pain relieving, Squama Manis, Olibanum, Myrrha blood circulation promoting and blood stasis dispelling, full side's blood stasis dispelling softening the hard mass, loose and separate pain relieving, promoting blood circulation to remove obstruction in the collateral, medicine meet cyclomastopathy QI and blood activity imbalance, and wet the friendship with QI and blood of the stasis of blood tied in newborn network and morbific traditional Chinese medical science pathogeny.
Table 2 carries out three courses of treatment the treatment of (menstrual cycle is a course of treatment) with medicine in the present embodiment and GUIZHI FULING JIAONANG contrast treatment 152 routine patients, and wherein 76 people are the treatment group, and 76 people are matched group.The total effective rate of treatment group is 96%, the total effective rate 74% of matched group; The cure rate of treatment group reaches 87%, and the cure rate of matched group is 53%.
Table 2
| Group | Patient's (number) | Administrated method | Cure (example) | Produce effects (example) | Effectively (example) | Invalid (example) |
| The treatment group | 76? | Twice/day; Two/time | 66? | 4? | 3? | 3? |
| Matched group | 76? | Three times/day; Three/time | 40? | 10? | 6? | 20? |
Present embodiment treatment to mastadenoma, thyroid tumor in clinical experiment also has significant curative effect.
Example 1: Chen, woman, 37 years old, the cadre, on May 20 2003 first visit date, patient both sides lump in breast is hypodynia 1 year slightly, the right breast lump is bigger, through breathing out the First Academy of medical university pathologic finding, is reported as cyclomastopathy, determine operative treatment, the patient disagrees with operation, takes the course of treatment of newborn anti-tumor capsule that disappears, patient's distending pain of the breast disappears, the patient is that lump diminishes to the examination in hospital result, recovers, and patient is very much satisfied.Pay a return visit after 2 years, do not see recurrence.
Example 2: poplar, the woman, 40 years old, the peasant, on March 24 2004 first visit date, the patient found two of right breast lumps in 2002, did colorful ultrasonic in provincial hospital and was diagnosed as " mastadenoma " pernicious i.e. " breast carcinoma ", two lumps are respectively 3 * 3.5cm, 3.5 * 2.5cm, often with taking out the sample pain of pulling, be drawn to the bilateral oxter, provincial hospital advises its operative treatment, the patient disagrees with operation, take and disappear newborn anti-tumor capsule after two courses of treatment, the patient finds that lump disappears, and fully recovers to the examination in hospital result, the patient continues to have taken a course of treatment again, is consolidated.Visit and do not see recurrence in 2 years.
Example 3: Chen, man 28 years old, workman, on February 5 2005 first visit date, the patient finds throat portion kept left a lump, dysphagia on ordinary days, this disease causes patient body to be become thin, and is unhappy, and the First Academy of medical university is diagnosed as " thyroid tumor " in the Kazakhstan, and inform and want operative treatment that the patient disagrees with operation, takes to disappear newborn anti-tumor capsule after course of treatment, the patient swallows smoothly, the result is to examination in hospital, and neck region lump diminishes, promptly gets well very soon.Visit and do not see recurrence in 1 year.
Claims (1)
1. medicine for the treatment of cyclomastopathy is characterized in that the capsule for the treatment of cyclomastopathy made by the Squama Manis of 17 parts of Calculus Boviss, 7 portions of Realgars, 30 parts of Nidus Vespaes, 20 parts of Olibanums, 20 parts of Myrrhas, 20 parts of Bulbus Fritillariae Cirrhosaes, 23 portions of Sargassums, 20 parts of Scorpio, 20 parts of Gekko Swinhonis, 20 parts of processes of preparing Chinese medicine, 3 parts Mylabris, 14 parts Scolopendra, 20 parts of Pseudobulbus cremastrae seu pleiones, 20 parts of Semen Vaccariae, 20 parts of Eupolyphaga Seu Steleophagas, 1 part of Venenum Bufonis, 6 parts of Cinnabaris, 20 parts of Cornu Cervi Degelatinatums, 7 parts of Semen Sinapis Albaes according to ratio of weight and number.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2007100720591A CN101041015B (en) | 2007-04-19 | 2007-04-19 | Medicine for treating hyperplasia of mammary glands |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2007100720591A CN101041015B (en) | 2007-04-19 | 2007-04-19 | Medicine for treating hyperplasia of mammary glands |
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| CN101041015A CN101041015A (en) | 2007-09-26 |
| CN101041015B true CN101041015B (en) | 2011-05-18 |
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| CN2007100720591A Expired - Fee Related CN101041015B (en) | 2007-04-19 | 2007-04-19 | Medicine for treating hyperplasia of mammary glands |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102205071B (en) * | 2011-05-28 | 2012-07-04 | 吴汉利 | Chinese medicinal composition for treating thyroid cyst |
| CN104189495B (en) * | 2014-09-16 | 2017-05-17 | 李爱新 | Traditional Chinese medicine preparation for treating breast cancer and preparation method thereof |
| CN105998626A (en) * | 2016-07-12 | 2016-10-12 | 袁威成 | Traditional Chinese medicine for treating hyperplasia, pain and lumps of mammary glands |
| CN107334924A (en) * | 2017-08-01 | 2017-11-10 | 张培芝 | A kind of Chinese medicine composition for treating the intractable proliferation of mammary gland |
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|---|---|---|---|---|
| CN1136909C (en) * | 2002-01-27 | 2004-02-04 | 郭朗轩 | Liniment 'Rubikang' and its preparing process |
| CN1679828A (en) * | 2005-01-14 | 2005-10-12 | 赵庆丽 | Medicine composition for treating cyclomastopathy |
| CN1857550A (en) * | 2006-03-20 | 2006-11-08 | 南京同仁堂药业有限责任公司 | Medicine composition for treating lobular hyperplasia of mammary gland and its preparing method |
| CN1310659C (en) * | 2005-09-09 | 2007-04-18 | 郝天发 | Tongue dropping medicine pill for diminishing inflammation and detoxicating |
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2007
- 2007-04-19 CN CN2007100720591A patent/CN101041015B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1136909C (en) * | 2002-01-27 | 2004-02-04 | 郭朗轩 | Liniment 'Rubikang' and its preparing process |
| CN1679828A (en) * | 2005-01-14 | 2005-10-12 | 赵庆丽 | Medicine composition for treating cyclomastopathy |
| CN1310659C (en) * | 2005-09-09 | 2007-04-18 | 郝天发 | Tongue dropping medicine pill for diminishing inflammation and detoxicating |
| CN1857550A (en) * | 2006-03-20 | 2006-11-08 | 南京同仁堂药业有限责任公司 | Medicine composition for treating lobular hyperplasia of mammary gland and its preparing method |
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