CN101036735A - External-use medicine for dermatosis and its preparation - Google Patents

Abstract

The invention discloses an external remedy for dermatosis, belonging to traditional Chinese medicine domain. Its feature lies in that it is composed of 80-120 portions of lycoris radiata, 50-80 portions of borneol, 50-80 portions of menthol, 50-100 portions of camphor, 100-200 portions of southenwood. The ethanol which is 90-95% of the full weight and the acetic acid which is 5-10% of the full weight is equably mixed to obtain ethanol-acetic acid mixed liquor. The lycoris radiata, borneol, menthol, camphor and southenwood are taken according to the above ratio, and then added to the ethanol-acetic acid mixed liquor until the mixed liquor submerges the crude medicines. After closed immersion for 15-20 days and filtrating, the filtrate is just the said external remedy. The invention has features of remarkable therapeutic efficacy, short period of treatment, fast effect, uneasy to recur.

Description

Dermopathic medicine for external use of a kind of treatment and preparation method thereof

Technical field

The invention belongs to the field of Chinese medicines, relate in particular to the dermopathic medicine for external use of a kind of treatment, also relate to its preparation method simultaneously.

Background technology

Dermatosis is the commonly encountered diseases and the frequently-occurring disease of human body, and wherein tinea is divided into tinea capitis, tinea corporis, tinea manus and pedis, tinea cruris, tinea versicolor, Tinea and microbid etc.Alopecia areata is a kind of patchy alopecia trichopathy of limitation that takes place suddenly.Its lesion scalp is normal, NIP and subjective symptoms.The primary disease course of disease is through slow, but spontaneous remission and recurrence.Neurodermatitis has another name called chronic simple lichen.The traditional Chinese medical science is called neurodermatitis or stubborn dermatitis is a kind of common chronic dermatosis, is feature with skin lichenification and violent pruritus.Main clinical manifestation: primary disease is more common in youth or adult, and the old people is more rare, and the child does not generally fall ill.During onset, pars affecta skin often only has pruritus and does not have the erythra generation.After often scratching or rubbing, just occur the foxtail millet gruel to the Semen phaseoli radiati size to pimple, last for a long time slightly, because of pimple increases day by day, intensive fusion forms that dermatoglyph is deepened and the patch of the typical lichenification that cutaneous ridge swells.Though this type of dermopathic kind of treatment is more at present, effect is not good enough, and very easily recurrence.

Summary of the invention

The object of the present invention is to provide a kind of therapeutic effect significantly, short treating period, instant effect, be difficult for the dermopathic medicine for external use of treatment of recurrence.

Another object of the present invention also is to provide this to treat the preparation method of dermopathic medicine for external use.

The present invention treats dermopathic medicine for external use component and consumption be the inventor according in, doctor trained in Western medicine is clinical dialectical to dermatosis, in conjunction with secret prescription handed down in the family from generation to generation, sum up clinical experience for many years, carry out that a large amount of repetition tests draws, each component and consumption all have better curative effect in the following weight parts scope:

Bulbus Lycoridis Radiatae 80-120 part Borneolum Syntheticum 50-80 part Mentholum 50-80 part

Camphora 50-100 part Herba Artemisiae Annuae 100-200 part.

Preferred each amounts of components is:

50 parts of 50 parts of Mentholums of 100 parts of Borneolum Syntheticums of Bulbus Lycoridis Radiatae

100 parts of 50 portions of Herba Artemisiae Annuaes of Camphora.

The preparation method of the active ingredient of medicine of the present invention comprises the steps:

(1) preparation of ethanol-acetic acid mixed liquor: will account for the ethanol and the acetic acid mix homogeneously that accounts for gross weight 5-10% of gross weight 90-95%, and get ethanol-acetic acid mixed liquor;

(2) take by weighing Bulbus Lycoridis Radiatae, Borneolum Syntheticum, Mentholum, Camphora and Herba Artemisiae Annuae by said ratio, add ethanol-acetic acid mixed liquor, can flood medical material and get final product, sealing was soaked 15-20 days then, filtered, and filtrate promptly.

Medicine for external use of the present invention, selecting natural plant for use is raw material, utilizes the comprehensive function treatment dermatosis of each component, to the human body safe without toxic side effect, free from extraneous odour, and cheap.Show through clinical observation, to various tinea, alopecia, therapeutic effect such as dermatitis significantly, short treating period, instant effect, be difficult for recurrence, have sterilization, antiinflammatory, antipruritic, promote skin metabolism, activate normally immunity of skin, recover the effect of the growth of skin cell tissue.

The specific embodiment

Below clinical observation on the therapeutic effect test by medicine for external use of the present invention further set forth the beneficial effect of medicine of the present invention.

Test example: the clinical observation of the external-use tincture of the embodiment of the invention 1 gained

(1) physical data

Meet alopecia areata alopecia patient 60 examples, the shortest person of the course of disease is 1 year, elder is 12 years; Neurodermatitis patient 60 examples, the shortest person of the course of disease are 1 year, and elder is 10 years; Tinea pedis patient's 200 examples, the shortest person of the course of disease are 1 year, and elder is 13 years.

(2) Therapeutic Method

The alopecia areata alopecia patient is applied in whole scalp position, every day 2-3 time after external-use tincture is exchanged uniform in 1: 1 ratio with cold boiled water; Neurodermatitis is applied in disease sites with external-use tincture, every day 1-2 time; Tinea pedis patient places external-use tincture in the footwear and puts on barefoot, or smears the affected part after the foot bath every night.

(3) efficacy assessment standard

Produce effects: symptomatology is eliminated;

Effectively: cardinal symptom is eliminated substantially;

Invalid: and compare the each side no change or the person of increasing the weight of before the treatment.

(4) therapeutic effect

The sick kind	The example number	Produce effects		Effectively		Invalid		Total effective rate %
										The example number	Cure rate %	The example number	Cure rate %	The example number	Cure rate %
Alopecia areata alopecia		60	58	96.67	2	3.33	0										100
	Neurodermatitis							60	60	100					100
Tinea pedis		200	100	100													100

The shortest person treatment course of treatment is 3 months to bald property hair loss patient, and elder is 8 months; The neurodermatitis patient treatment course of treatment, the shortest person was 2 weeks, and elder was 4 weeks; The tinea pedis patient treatment course of treatment, the shortest person was 2 weeks, and elder was 3 weeks.Follow up a case by regular visits to and do not see recurrence in 3 years.

Come further to set forth the preparation method of medicine for external use of the present invention by the following examples.

Embodiment 1:

The preparation method of the tincture of medicine of the present invention comprises the steps:

(1) preparation of ethanol-acetic acid mixed liquor:, get ethanol-acetic acid mixed liquor with 3325kg ethanol and 175kg acetic acid mix homogeneously;

(2) take by weighing Bulbus Lycoridis Radiatae 100kg, Borneolum Syntheticum 50kg, Mentholum 50kg, Camphora 50kg and Herba Artemisiae Annuae 100kg, add ethanol-acetic acid mixed liquor, can flood medical material and get final product, sealing was soaked 15-20 days then, filtered, and filtrate promptly.

Embodiment 2:

The preparation method of the tincture of medicine of the present invention comprises the steps:

(1) preparation of ethanol-acetic acid mixed liquor:, get ethanol-acetic acid mixed liquor with 3510kg ethanol and 390kg acetic acid mix homogeneously;

(2) take by weighing Bulbus Lycoridis Radiatae 80kg, Borneolum Syntheticum 80kg, Mentholum 70kg, Camphora 100kg and Herba Artemisiae Annuae 200kg, add ethanol-acetic acid mixed liquor, can flood medical material and get final product, sealing was soaked 15-20 days then, filtered, and filtrate promptly.

Embodiment 3:

The preparation method of the tincture of medicine of the present invention comprises the steps:

(1) preparation of ethanol-acetic acid mixed liquor:, get ethanol-acetic acid mixed liquor with 3720kg ethanol and 280kg acetic acid mix homogeneously;

(2) take by weighing Bulbus Lycoridis Radiatae 120kg, Borneolum Syntheticum 60kg, Mentholum 80kg, Camphora 80kg and Herba Artemisiae Annuae 150kg, add ethanol-acetic acid mixed liquor, can flood medical material and get final product, sealing was soaked 15-20 days then, filtered, and filtrate promptly.

The above, it only is preferred embodiment of the present invention, be not that the present invention is done any pro forma restriction, any technical solution of the present invention content that do not break away from,, all still belong in the scope of technical solution of the present invention any simple modification, equivalent variations and modification that above embodiment did according to technical spirit of the present invention.

Claims (3)

1, the dermopathic medicine for external use of a kind of treatment is characterized in that it is the medicament of being made by the raw material of following weight parts:

Bulbus Lycoridis Radiatae 80-120 part Borneolum Syntheticum 50-80 part Mentholum 50-80 part

Camphora 50-100 part Herba Artemisiae Annuae 100-200 part.

2, the dermopathic medicine for external use of treatment as claimed in claim 1, wherein the weight proportion of each raw material is:

50 parts of 50 parts of Mentholums of 100 parts of Borneolum Syntheticums of Bulbus Lycoridis Radiatae

100 parts of 50 portions of Herba Artemisiae Annuaes of Camphora.

3, the preparation method of the dermopathic medicine for external use of treatment as claimed in claim 1 or 2 is characterized in that:

(1) preparation of ethanol-acetic acid mixed liquor: will account for the ethanol and the acetic acid mix homogeneously that accounts for gross weight 5-10% of gross weight 90-95%, and get ethanol-acetic acid mixed liquor;

(2) take by weighing Bulbus Lycoridis Radiatae, Borneolum Syntheticum, Mentholum, Camphora and Herba Artemisiae Annuae by said ratio, add ethanol-acetic acid mixed liquor, can flood medical material and get final product, sealing was soaked 15-20 days then, filtered, and filtrate promptly.