CN101028450A - Medicinal composition for treating cardica cerebrovascular diseases - Google Patents

Abstract

A Chinese medicine in the form of honeyed pills for treating cardiovascular and cerebrovascular diseases is prepared from 23 Chinese-medicinal materials including gastrodia tuber, capejasmine fruit, scutellaria root, corpion, etc.

Description

A kind of pharmaceutical composition for the treatment of cardiovascular and cerebrovascular disease

Technical field:

The present invention relates to a kind of medicine for the treatment of cardiovascular and cerebrovascular disease, especially relating to a kind of is the pharmaceutical composition of the treatment cardiovascular and cerebrovascular disease of feedstock production with the Chinese herbal medicine.

Background technology:

Cardiovascular and cerebrovascular disease generally comprises diseases such as cerebral thrombosis, hypertension, hyperlipidemia, cerebral arteriosclerosis, myocardial infarction, cerebral ischemia, premature beat, and this class disease is a kind of common multiple disease, seriously influences patient's physical and mental health and daily life.

The real cause of disease of cardiovascular and cerebrovascular disease is three fat (cholesterol, triglyceride, the phospholipid) content overproof in the blood, and disequilibrium makes the blood sticking silk fabric that becomes, and the formation blood fat group that is sticked together mutually, the flow velocity of blood is slowed down, and oxygen supply is untimely, thereby causes cardiovascular and cerebrovascular disease.So, as long as adjusting three fat and balance three fat are only the basic of treatment cardiovascular and cerebrovascular disease.

At present, the treatment cardiovascular and cerebrovascular disease is based on Western medicine, and the medicine narrow range of suiting the medicine to the illness, and needs to obey multiple Western medicine sometimes, can not Comprehensive Treatment, furthermore the side effect of Western medicine is also very big.Such as: depressor can only temporarily play hypotensive effect, and blood pressure can rise again after the drug withdrawal; Heart disease is by temporary transient symptomatic treatment such as heart tonifying, coronary artery dilator, only plays mitigation.

Summary of the invention:

Technical problem to be solved by this invention aims to provide the pharmaceutical composition of the treatment cardiovascular and cerebrovascular disease that a kind of curative effect is fast, effect is lasting, have no side effect.

The present invention according to the traditional Chinese medical science to pathogenetic understanding of cardiovascular and cerebrovascular disease and Therapeutic Principle, with reference to the modern pharmacological research achievement, and clinical practice for many years, from motherland's medical treasure-house, filter out following raw material of Chinese medicine medicine, by traditional Chinese medical science prescription theory, make pharmaceutical composition.

Pharmaceutical composition of the present invention is made by following raw materials in weight portion medicine:

Rhizoma Gastrodiae 80-120 Ramulus Uncariae Cum Uncis 20-60 Herba Taxilli 30-70 Fructus Gardeniae 25-80

Radix Scutellariae 20-60 Cortex Eucommiae 40-80 Radix Achyranthis Bidentatae 75-120 Caulis Polygoni Multiflori 40-80

Poria cum Radix Pini 60-100 Herba Leonuri 30-75 Concha Haliotidis 80-120 Scorpio 20-70

Hirudo 50-100 Pheretima 60-100 Flos Carthami 30-60 Rhizoma Chuanxiong 80-130

Radix Angelicae Sinensis 25-80 Radix Salviae Miltiorrhizae 70-120 Radix Astragali 60-120 Scolopendra 50-90

Rhizoma Coptidis 30-80 Cortex Phellodendri 20-75 Squama Manis 30-75

The raw material of Chinese medicine of said ratio is made oral pharmaceutical composition.

Optimum weight part proportioning of pharmaceutical composition of the present invention is:

Rhizoma Gastrodiae 100 Ramulus Uncariae Cum Uncis 40 Herba Taxillis 50 Fructus Gardeniaes 50 Radix Scutellariaes 40

The Cortex Eucommiae 60 Radix Achyranthis Bidentataes 100 Caulis Polygoni Multiflori 60 Poria cum Radix Pinis 80 Herba Leonuris 50

Concha Haliotidis 100 Scorpios 50 Hirudos 80 Pheretimas 80 Flos Carthamis 560

Rhizoma Chuanxiong 100 Radix Angelicae Sinensis 50 Radix Salviae Miltiorrhizaes 100 Radixs Astragali 1020 Scolopendras 70

Rhizoma Coptidis 50 Cortex Phellodendris 50 Squama Maniss 50

The raw material of Chinese medicine of said ratio is made the combination of oral medication of honeyed pill dosage form.

The inventor is by consulting amount of literature data and through clinical practice for many years, determine that " fill blood, purify the blood, promoting blood circulation, by arthralgia due to stagnation of blood, blood circulation promoting and blood stasis dispelling, eliminating evil collateral dredging " is the principles of formulating prescriptions, and then regulate three fat, and blood fat group is faded away, smooth flexible up to blood vessel wall.

Rhizoma Gastrodiae endogenous wind stopping relieving convulsion, suppressing the hyperactive liver and subsiding YANG, wind-damp dispelling, stopping numbness pain in the prescription of the present invention; Ramulus Uncariae Cum Uncis endogenous wind stopping relieving convulsion, heat clearing away suppressing the hyperactive liver; Herba Taxilli wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening; Fructus Gardeniae pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body; Radix Scutellariae heat clearing and damp drying, eliminating fire and detoxication, hemostasis; Cortex Eucommiae invigorating the liver and kidney, bone and muscle strengthening; Radix Achyranthis Bidentatae blood circulation promoting and blood stasis dispelling, invigorating the liver and kidney, bone and muscle strengthening, inducing diuresis for treating stranguria syndrome, conducting blood to flow downwards; Caulis Polygoni Multiflori tranquilizing by nourishing the heart, collateral dredging dispel the wind; Poria cum Radix Pini exorcises evil spirits that gas, spasmolytic are throbbed with fear, happy key, peace soul, support spirit, tonify deficiency is weary; Herba Leonuri blood circulation promoting and blood stasis dispelling, inducing diuresis to remove edema; Concha Haliotidis suppressing the hyperactive liver and subsiding YANG, liver heat removing and eyesight improving; Scorpio endogenous wind stopping relieving convulsion, detoxicating and resolving stagnation of pathogens, removing obstruction in the collateral to relieve pain; The Hirudo removing blood stasis; The Pheretima clearing heat for calming endogenous wind, relieving asthma, collateral dredging, diuresis; The Flos Carthami blood circulation promoting and blood stasis dispelling; Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping; Chinese angelica blood supplementing, invigorate blood circulation, pain relieving, intestine moistening; Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, removing heat from blood eliminating carbuncle, nourishing blood to tranquillize the mind; Radix Astragali tonifying Qi and lifting yang, benefit are defended consolidating superficial resistance, promoting pus discharge and tissue regeneration strengthening, diuretic detumescent; Scolopendra endogenous wind stopping relieving convulsion, detoxicating and resolving stagnation of pathogens, removing obstruction in the collateral to relieve pain; Rhizoma Coptidis heat clearing and damp drying, eliminating fire and detoxication; Cortex Phellodendri heat clearing and damp drying, eliminating fire and detoxication, reducing the asthenic fever; Squama Manis promoting blood circulation to restore menstrual flow, detumescence and apocenosis.Above-mentioned 23 flavor medicines are worked in coordination, the effect of collaborative playing " fill blood, purify the blood, promoting blood circulation, by arthralgia due to stagnation of blood, blood circulation promoting and blood stasis dispelling, eliminating evil collateral dredging ", thereby regulate three fat, balance three fat meet the traditional Chinese medical science to pathogenetic understanding of cardiovascular and cerebrovascular disease and Therapeutic Principle.

The present invention is made by pure Chinese medicine, no side effects, and preparation technology is simple, stable curative effect, effective percentage reaches 93%.

For showing therapeutic effect of the present invention, the inventor is as follows to the clinical treatment situation statistics of 100 routine various cardiovascular and cerebrovascular diseases.

1. physical data

Hyperpietic 17 people, man 1 people more than 60 years old, woman 5 people more than 60 years old, male 40-60 year 6 people, women 40-60 year 5 people;

Cerebral thrombus patient 20 people, man 3 people more than 60 years old, woman 5 people more than 60 years old, male 40-60 year 8 people, women 40-60 year 4 people;

Cardiac 14 people, man 3 people more than 60 years old, woman 2 people more than 60 years old, male 40-60 year 5 people, women 40-60 year 4 people;

Hyperlipemic patients 16 people, man 5 people more than 60 years old, woman 6 people more than 60 years old, male 40-60 year 2 people, women 40-60 year 3 people;

Cerebral Infarction Patients 15 people, man 8 people more than 60 years old, male 40-60 year 3 people, women 40-60 year 4 people;

Myocardial infarction patient 18 people, man 6 people more than 60 years old, woman 5 people more than 60 years old, male 40-60 year 3 people, women 40-60 year 4 people.

2. Therapeutic Method

Seriously ill person every day three times, each 3 balls, sick the lighter every day twice, each 2 balls, every ball 15 grams, serve on three courses of treatment at 30 days course of treatment.

3. efficacy assessment standard

Produce effects: clinical symptom disappearance, functional rehabilitation is normal, cures and does not have recurrence after 1 year.

Take a turn for the better: clinical symptom relief, stable disease.

Invalid: symptom does not have obvious improvement.

4. therapeutic outcome sees the following form

Disease	Case load	Produce effects	Take a turn for the better	Invalid	Effective percentage
						Hypertension	17	11	5	1	94％
Cerebral thrombosis	20	15	4	1	95％
						Heart disease	14	9	4	1	93％
Hyperlipidemia	16	14	1	1	94％
						Cerebral infarction	15	9	5	1	93％
Myocardial infarction	18	14	3	1	94％

From above data show, the present invention treats various cardiovascular and cerebrovascular diseases all better curative effect, and effective percentage reaches 93%.

Model case:

1, Hu Zhendong, man, 48 years old, suffered from cerebral thrombosis, myocardial infarction 6 years, facial hemiparalysis, sialorrhea, walking needs the people to assist in, after taking the present invention (melting the bolt ball) 3 courses of treatment, effect has had tangible improvement, taken 2 courses of treatment again after, do not choose on foot and held up, the symptom of facial hemiparalysis obviously alleviates, also sialorrhea not, and sequela has all disappeared.

2, Lee protects, the man, and 45 years old, suffered from cerebral infarction, hypertension, hyperlipidemia 5 years, language has obstacle when being in a bad way, and the right side body is inactive, goes to toilet on foot and all must someone help, and melts the bolt ball after 1 month by taking, and life just can have been taken care of oneself fully.

3, Liu Guang, the man 55 years old, got myocardial infarction in 2004, after doing support operation and leaving hospital, the state of an illness has had improvement, but feels sensation of oppression over the chest with shortness of breath, takes to melt the bolt ball and just feel that breast is not vexed 2 courses of treatment, also easily how whole body, used a course of treatment at last again, symptom complete obiteration uncomfortable in chest, all very normal so far.

4, Wang Xiu, the woman 56 years old, suffers from myocardial ischemia more than 1 year, like upstairs heart all will be jumped out, weak from head to foot, what is lived is not all done, and takes to melt the bolt ball after 3 courses of treatment, last heart is downstairs jumped to such an extent that do not resembled former severity so, general housework can both have been done, and to examination in hospital, every index is all normal.

5, Li Ayu, the woman 65 years old, suffers from cerebral thrombosis, arrhythmia 5 years, once repeatedly morbidity was in hospital, and numbness of hands and feet be can't take care of oneself, and all are all looked after by my old man, listened relatives to introduce and melted the bolt ball, just used a course of treatment, trick as a result is not numb, continues to have used 2 courses of treatment, state of an illness rehabilitation.

6, Wu is with, man, 49 years old, suffers from a heart complaint, hypertension nervous breathing hard, heart also stops sometimes steathily, has spent a lot of money in the past, does not all cure, and takes to melt two weeks of bolt ball, nervous symptom of breathing hard has just disappeared, and after 2 months, blood pressure is also normal by the time, and heart disease does not commit excesses yet again.

The specific embodiment:

Embodiment 1

Rhizoma Gastrodiae 80 Ramulus Uncariae Cum Uncis 20 Herba Taxillis 30 Fructus Gardeniaes 25 Radix Scutellariaes 20

The Cortex Eucommiae 40 Radix Achyranthis Bidentataes 75 Caulis Polygoni Multiflori 40 Poria cum Radix Pinis 60 Herba Leonuris 30

Concha Haliotidis 80 Scorpios 20 Hirudos 50 Pheretimas 60 Flos Carthamis 30

Rhizoma Chuanxiong 80 Radix Angelicae Sinensis 25 Radix Salviae Miltiorrhizaes 70 Radixs Astragali 60 Scolopendras 50

Rhizoma Coptidis 30 Cortex Phellodendris 20 Squama Maniss 30

Preparation method: take by weighing raw material by prescription, clean, oven dry is ground into 100-150 order fine powder, and fine powder and ripe Mel is even by part by weight blending in 3: 1, and every ball weighs 15 grams.

Embodiment 2

Rhizoma Gastrodiae 100 Ramulus Uncariae Cum Uncis 40 Herba Taxillis 50 Fructus Gardeniaes 50 Radix Scutellariaes 40

The Cortex Eucommiae 60 Radix Achyranthis Bidentataes 100 Caulis Polygoni Multiflori 60 Poria cum Radix Pinis 80 Herba Leonuris 50

Concha Haliotidis 100 Scorpios 50 Hirudos 80 Pheretimas 80 Flos Carthamis 50

Rhizoma Chuanxiong 100 Radix Angelicae Sinensis 50 Radix Salviae Miltiorrhizaes 100 Radixs Astragali 100 Scolopendras 70

Rhizoma Coptidis 50 Cortex Phellodendris 50 Squama Maniss 50

Method for making is with embodiment 1.

Embodiment 3

Rhizoma Gastrodiae 120 Ramulus Uncariae Cum Uncis 60 Herba Taxillis 70 Fructus Gardeniaes 80 Radix Scutellariaes 60

The Cortex Eucommiae 80 Radix Achyranthis Bidentataes 120 Caulis Polygoni Multiflori 80 Poria cum Radix Pinis 100 Herba Leonuris 75

Concha Haliotidis 120 Scorpios 70 Hirudos 100 Pheretimas 100 Flos Carthamis 60

Rhizoma Chuanxiong 130 Radix Angelicae Sinensis 80 Radix Salviae Miltiorrhizaes 120 Radixs Astragali 120 Scolopendras 90

Rhizoma Coptidis 80 Cortex Phellodendris 75 Squama Maniss 75.

Claims (2)

1, a kind of pharmaceutical composition for the treatment of cardiovascular and cerebrovascular disease, it is characterized in that: it is made by following Chinese medicinal raw materials in portion by weight:

Rhizoma Gastrodiae 80-120 Ramulus Uncariae Cum Uncis 20-60 Herba Taxilli 30-70 Fructus Gardeniae 25-80

Radix Scutellariae 20-60 Cortex Eucommiae 40-80 Radix Achyranthis Bidentatae 75-120 Caulis Polygoni Multiflori 40-80

Poria cum Radix Pini 60-100 Herba Leonuri 30-75 Concha Haliotidis 80-120 Scorpio 20-70

Hirudo 50-100 Pheretima 60-100 Flos Carthami 30-60 Rhizoma Chuanxiong 80-130

Radix Angelicae Sinensis 25-80 Radix Salviae Miltiorrhizae 70-120 Radix Astragali 60-120 Scolopendra 50-90

Rhizoma Coptidis 30-80 Cortex Phellodendri 20-75 Squama Manis 30-75.

2, a kind of pharmaceutical composition for the treatment of cardiovascular and cerebrovascular disease according to claim 1, it is characterized in that: it is the honeyed pill of being made by following Chinese medicinal raw materials in portion by weight:

Rhizoma Gastrodiae 100 Ramulus Uncariae Cum Uncis 40 Herba Taxillis 50 Fructus Gardeniaes 50 Radix Scutellariaes 40

The Cortex Eucommiae 60 Radix Achyranthis Bidentataes 100 Caulis Polygoni Multiflori 60 Poria cum Radix Pinis 80 Herba Leonuris 50

Concha Haliotidis 100 Scorpios 50 Hirudos 80 Pheretimas 80 Flos Carthamis 560

Rhizoma Chuanxiong 100 Radix Angelicae Sinensis 50 Radix Salviae Miltiorrhizaes 100 Radixs Astragali 100 Scolopendras 70

Rhizoma Coptidis 50 Cortex Phellodendris 50 Squama Maniss 50.