CN101028372B - Chinese medicinal decoction for treating hives - Google Patents
Chinese medicinal decoction for treating hives Download PDFInfo
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- CN101028372B CN101028372B CN200710065502A CN200710065502A CN101028372B CN 101028372 B CN101028372 B CN 101028372B CN 200710065502 A CN200710065502 A CN 200710065502A CN 200710065502 A CN200710065502 A CN 200710065502A CN 101028372 B CN101028372 B CN 101028372B
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Abstract
A Chinese medicine in the form of decoction for treating urticaria is prepared from more than 10 Chinese-medicinal materials including Chinese angelica root, white peony root, pilose asiabell root, tangerine peel, etc.
Description
Technical field
The present invention relates to the urticarial Chinese medicine decoction of a kind of treatment, is that a kind of urticaria for the treatment of is the Chinese medicine decoction of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Urticaria is owing to skin, the little vascular reactivity expansion of mucosa and permeability increase a kind of localized edema reaction that produces.Primary disease is more common, and the people of about 15%-25% was taken place once in life at least.The urticaria traditional Chinese medical science is called urticaria, rubella, red rash, miliaria alba, acute angioneurotic edema, urticaria etc.Be commonly called as terrible wind pimple, rubella wheal, bellows chamber etc.As saying that " the evil exopathogenic heat of husband is skin, meets wind and cold and hinders and then play urticaria, and overabundant heat is red complexion then, and wind color at most is white, and very the person itches bitterly, and that scratches then becomes skin ulcer in " Standards of Diagnosis and Treatment air door "." " urticaria person, the sound granule is had a nightmare among skin, the loathing of cold pruritus all over of generating heat and for example " surgery great achievement urticaria ".Classical prescription: exposure to the wind after sweating due to overstrain is a Cuo numbness.The little red complexion of heat, heat is darkish complexion very., control and should lung heat clearing fall expectorant and induce sweat at lung by expectorant heat.”
The urticaria clinical manifestation is the localized edema welt that differs in size.The welt color can be cerise, pale red, pale asphyxia or skin-color, and form can rounded, oval, annular or irregular shape.Welt can take place suddenly in several minutes, can disappear in several minutes to a few hours, did not stay any vestige, but this plays that again, outbreak repeatedly.Its Clinical symptoms is stepped back no vestige for taking place rapidly and disappearing, and itches with play.Severe patient can be with headache, dizziness, arthralgia, stomachache, nausea,vomiting,diarrhea, uncomfortable in chest, nervous, hoarseness, dyspnea, severe patient can occur that laryngeal edema, pale complexion, heart rate quicken, anaphylactic shock such as pulse is thin and delicate, blood pressure drops, confusion, threat to life.Clinical in course of disease length, generally anxious onset, the course of disease was called acute urticaria at three months with interior person, and its morbidity is hurried, the welt number is more, how with General Symptoms; Welt shows effect repeatedly and is called chronic urticaria above person more than three months, and is few for a long time during its welt, but most welt is less, and General Symptoms is lighter.
The common cause of disease of urticaria has: 1. food: as fish, shrimp, Eriocheir sinensis, egg or milk etc.2. medicine: penicillin, furazolidone, serum, vaccine etc.3. infect: tonsillitis, viral hepatitis, Enterozoa etc.4. animal and plant factor: as sucking scurf, feather or the pollen etc. of animal.5. physics and chemical factor: as hot and cold, daylight, friction and pressure etc.6. internal organs and general disease and nervously all can bring out primary disease.
Urticaria also has specific type urticaria, (1) peptone urticaria (acute protein anaphylaxis urticaria) except that being divided into acute urticaria and chronic urticaria.(2) cold urticaria is divided into again: familial cold urticaria and acquired cold urticaria.(3) heat urticaria.(4) cholinergic urticaria.(5) solar urticaria.(6) pressure urticaria.(7) aquagenic urticaria.(8) serum sickness urticaria.(9) autoimmunity Progesterone urticaria.(10) angioedema (huge urticaria).(11) factitial urticaria.Acute urticaria disappeared through a few days or several weeks, and reason is more easily traced, and disappeared rapidly after dispeling the cause of disease.Chronic urticaria is shown effect repeatedly, does not heal throughout the year.Cause of disease complexity is difficult to find out, lives, brings mentally very big misery and inconvenience to the patient.Serious symptom when its acute attack can cause the shock of suffocating, threat to life.Therefore, the problem of relevant prevention minimizing chronic urticaria recurrence is the difficult point of present clinical treatment aspect.
The Chinese traditional treatment acute urticaria is single can to obtain good curative effect with treatment by Chinese herbs.Clinical syndrome differentiation is based on excess syndrome, heat syndrome, and common card has pattern of syndrome such as wind heat, blood hot air wind producing, the intestines and stomach be damp and hot, and ailment said due to cold or exposure is a main external cause, treats antipruritic based on dispelling wind; Be equipped with the medicine of relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, clearing away heat and cooling blood, heat clearing away purging FU-organs intestinal stasis relieving respectively.The chronic urticaria Chinese medical discrimination is many with deficiency syndrome, blood stasis syndrome.Common pattern of syndrome has: insufficiency of the spleen catching cold, weakened defensive QI; Deficiency of qi and blood; Give birth in the hepatic and renal YIN deficiency, wind syndrome caused by deficiency; Qi depression to blood stasis; Chong and Ren channel disorder etc.Treat respectively with invigorating the spleen and benefiting QI the cold expelling consolidating superficial resistance; Benefiting QI and nourishing blood, dispelling wind is antipruritic; Adjusting and reinforcing liver and kidney, nourishing blood to stop wind syndrome; Blood circulation promoting and blood stasis dispelling, dispelling wind for relieving itching; Regulating thoroughfare and controlling vessel is a method.
Doctor trained in Western medicine thinks that urticaria will prevent its recurrence, at first when finding clear and definite its cause of disease, is removed.But often the cause of disease is difficult to find clinically.So present western medical treatment is symptomatic treatment mostly.Traditional antihistaminic has stronger maincenter inhibition ability easily to produce the drowsiness side effect that waits, and the antihistaminic of a new generation does not have side effect such as drowsiness as astemizole, loratadine, cetirizine etc., and its short term effect is better, but late result is relatively poor.This is concerning treatment of Chronic Urticaria and reduce its relapse rate, and curative effect is often not ideal enough.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide the urticarial Chinese medicine decoction of a kind of treatment.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.0～4 parts in 1.0～4 parts of Poria of 1.5～6 parts of Radix Rehmanniae of the Rhizoma Atractylodis Macrocephalae
1.0～4 parts of 1.0～4 parts of Radix Bupleuri of 1.5～6 portions of Radix Glehniaes of Radix Angelicae Sinensis
0.1～2 part of 1.0～4 parts of Pericarpium Citri tangerinae of 1.5～6 parts of Cortex Dictamni of the Radix Paeoniae Alba
0.1～2 part of 0.1～2 part of Radix Saposhnikoviae of 1.0～4 parts of Fructus Kochiae of Radix Codonopsis
The weight proportion of each raw material of optimization formula of the present invention is:
From 1.5～2.5 parts in 1.5～2.5 parts of Poria of 2.5～3.5 parts of Radix Rehmanniae of art
1.5～2.5 parts of 1.5～2.5 parts of Radix Bupleuri of 2.5～3.5 portions of Radix Glehniaes of Radix Angelicae Sinensis
0.5～1.5 part of 1.5～2.5 parts of Pericarpium Citri tangerinae of 2.5～3.5 parts of Cortex Dictamni of the Radix Paeoniae Alba
0.5～1.5 part of 0.5～1.5 part of Radix Saposhnikoviae of 1.5～2.5 parts of Fructus Kochiae of Radix Codonopsis
The weight proportion of each raw material of optimum formula of the present invention is:
2 parts in 2 parts of Poria of 3 parts of Radix Rehmanniae of the Rhizoma Atractylodis Macrocephalae
2 parts of 2 parts of Radix Bupleuri of 3 portions of Radix Glehniaes of Radix Angelicae Sinensis
1 part of 2 parts of Pericarpium Citri tangerinae of 3 parts of Cortex Dictamni of the Radix Paeoniae Alba
1 part of 1 part of Radix Saposhnikoviae of 2 parts of Fructus Kochiae of Radix Codonopsis
Drug action mechanism among the present invention is as follows:
Rhizoma Atractylodis Macrocephalae property of medicine hardship, sweet, temperature.Return spleen, stomach warp.Has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.Can treat the weak of deficiency-weakness of spleen-QI, lack of appetite abdominal distention is had loose bowels, constipation, the dysuria of fluid-retention stagnating in the interior, edema, dizziness due to fluid-retention, cold-damp numbness, general pain, spontaneous sweating due to deficiency of QI, frequent fetal movement etc.(the 945th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis nature and flavor are sweet, hot, warm.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of loosening bowel to relieve constipation.Can be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea stimulates the menstrual flow, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, traumatic injury, ulcer sores etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 553rd page).
Radix Paeoniae Alba nature and flavor hardship, acid, be slightly cold.Return liver, spleen channel.Effect with suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating, antibiotic, thrombocytosis.Can treat that the pain over the hypochondriac region, dysentery stomachache, night sweat, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia, headache are dizzy, limb pain twin, blood deficiency and yellow complexion etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 432nd page).
The Radix Codonopsis nature and flavor are sweet, flat.Return spleen, lung meridian.Has invigorating the spleen and replenishing QI, the effect of spleen invigorating lung benefiting.Can treat deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, the dyspnea due to deficiency cough, interior-heat is quenched one's thirst.And compatibility is controlled malignant tumor such as osteosarcoma, leukemia, chorionic epithelioma, proctoptosis, uterine prolapse etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1031st page).
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
The Radix Glehniae property of medicine is sweet, cold.Attach to the lung and stomach meridians.Has nourishing YIN and clearing away lung-heat, the effect of reinforcing stomach reg fluid.Can treat dryness of the lung dry cough, the asthenia hemoptysis, deficiency of stomach-Yin, Tianjin wound is dried etc.(the 903rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Dictamni nature and flavor hardship, cold.Return spleen, stomach, urinary bladder channel.Has heat clearing and damp drying, the antidotal effect of dispeling the wind.Can treat damp and hot sore, yellow fluid is dripping, eczema, rubella, scabies skin ulcer leprosy, rheumatism pyretic arthralgia, jaundice dark coloured urine etc.(the 83rd page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The Poria nature and flavor are sweet, flat, light.GUIXIN, lung, spleen, kidney channel.Has eliminating dampness and diuresis, the effect of strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Can treat that dysuria, edema distension, phlegm retention cough with dyspnea, brain are throbbed with fear, have loose bowels in the loose stool, irritability, palpitation with fear, insomnia, forgetful, seminal emission, stranguria with turbid discharge, insufficiency of the spleen, stop that drink is not eaten, gastral cavity is vexed, three YIN malaria (malaria pathogen in three YIN) disease, heating do not heal, end empty YANG-depletion etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 898th page).
Radix Bupleuri nature and flavor hardship, be slightly cold.Return liver, gallbladder meridian.Effect with reconciling superficies and interior, soothing the liver, yang invigorating.Can treat alternate attack of chill and fever, fullness in the chest and hypochondriac pain, deafness, headache and dizziness, malaria, dysentery proctoptosis, menoxenia, uterine prolapse, flu, upper respiratory tract infection, hepatitis, cholecystitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1004th page).
Pericarpium Citri tangerinae property of medicine suffering, hardship, temperature.Return spleen, stomach, lung meridian.Having in the accent of regulating the flow of vital energy stopping nausea and vomiting by lowering the adverse flow of QI, the effect of drying dampness to eliminate phlegm.It is full vexed to treat septum pectorale, abdominal distention, anorexia, vomiting, hiccup; Cough with copious phlegm.Acute mastitis from the beginning of etc.(the 1668th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Kochiae nature and flavor suffering, hardship, cold.Return kidney, urinary bladder channel.Has clearing away heat-damp and promoting diuresis, the effect of dispelling wind for relieving itching.Can treat difficulty and pain in micturition, pudendal pruritus leukorrhagia, rubella, eczema, skin pruritus etc.(the 93rd page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Radix Saposhnikoviae nature and flavor suffering, sweet, temperature.Return bladder, liver, spleen channel.Have inducing diaphoresis to dispel wind, win and wet, the effect of relieving convulsion.Can treat headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus etc.(the 117th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis and the Radix Paeoniae Alba; With Radix Codonopsis, Radix Rehmanniae, Radix Glehniae, Cortex Dictamni, Poria and Radix Bupleuri is ministerial drug; With Pericarpium Citri tangerinae, the Fructus Kochiae and Radix Saposhnikoviae is adjuvant.All medicines are harmonious, and are total to the tool benefiting QI and nourishing blood, the effect of dispelling wind for relieving itching.The treatment urticaria has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment urticaria of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through animal acute toxicity experiment the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, the present invention need not decoct, no bitterness sense, rich in proteins in the medicine, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat urticaria, and urticarial prevention is also had good effect, and the treatment urticaria has determined curative effect, has no side effect taking convenience, cheap characteristics.
Further specify medicine of the present invention to treating urticarial therapeutic effect below by the clinical practice example.The urticaria curative effect determinate standard: 1. cure: welt disappears, and clinical sign disappears, and the person does not reaccess.2. take a turn for the better: welt disappear 30% or the back recurrent interval time that disappears prolong sx persons such as pruritus.3. do not heal: welt and pruritus do not have obvious improver, or the less than 30% that disappears.(the 859th page of chief editor's " traditional Chinese medical science disease diagnosis and treatment standard and prescription are selected for use " People's Health Publisher's calendar year 2001 version such as Dai Shen).
For showing medicine of the present invention, as follows through clinical test results to treating urticarial therapeutic effect; Treatment urticaria patient 35 examples, male's 19 examples, women's 16 examples, the age is 18～60 years old.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.27 examples of fully recovering account for 77%, and 6 examples that take a turn for the better account for 17%, and more 2 examples do not account for 6%, and total effective rate reaches 94%.After three course of therapy, symptoms such as patient's welt and pruritus all have clear improvement or fully recover.And patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
2 parts in 2 parts of Poria of 3 parts of Radix Rehmanniae of the Rhizoma Atractylodis Macrocephalae
2 parts of 2 parts of Radix Bupleuri of 3 portions of Radix Glehniaes of Radix Angelicae Sinensis
1 part of 2 parts of Pericarpium Citri tangerinae of 3 parts of Cortex Dictamni of the Radix Paeoniae Alba
1 part of 1 part of Radix Saposhnikoviae of 2 parts of Fructus Kochiae of Radix Codonopsis
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The urticaria decoction plastic packaging that the present invention makes is packed, and every bag of 210m1 is oral, one time one bag, every day two to three times.One month is a course of treatment.
Claims (3)
1. urticarial Chinese medicine decoction of treatment is characterized in that it is made by following raw materials by weight proportions:
1.0～4 parts in 1.0～4 parts of Poria of 1.5～6 parts of Radix Rehmanniae of the Rhizoma Atractylodis Macrocephalae
1.0～4 parts of 1.0～4 parts of Radix Bupleuri of 1.5～6 portions of Radix Glehniaes of Radix Angelicae Sinensis
0.1～2 part of 1.0～4 parts of Pericarpium Citri tangerinae of 1.5～6 parts of Cortex Dictamni of the Radix Paeoniae Alba
0.1～2 part of 0.1～2 part of Radix Saposhnikoviae of 1.0～4 parts of Fructus Kochiae of Radix Codonopsis.
2. the urticarial Chinese medicine decoction of a kind of treatment according to claim 1, wherein the weight proportion of each crude drug is:
1.5～2.5 parts in 1.5～2.5 parts of Poria of 2.5～3.5 parts of Radix Rehmanniae of the Rhizoma Atractylodis Macrocephalae
1.5～2.5 parts of 1.5～2.5 parts of Radix Bupleuri of 2.5～3.5 portions of Radix Glehniaes of Radix Angelicae Sinensis
0.5～1.5 part of 1.5～2.5 parts of Pericarpium Citri tangerinae of 2.5～3.5 parts of Cortex Dictamni of the Radix Paeoniae Alba
0.5～1.5 part of 0.5～1.5 part of Radix Saposhnikoviae of 1.5～2.5 parts of Fructus Kochiae of Radix Codonopsis.
3. the urticarial Chinese medicine decoction of a kind of treatment according to claim 1, wherein the weight proportion of each crude drug is:
2 parts in 2 parts of Poria of 3 parts of Radix Rehmanniae of the Rhizoma Atractylodis Macrocephalae
2 parts of 2 parts of Radix Bupleuri of 3 portions of Radix Glehniaes of Radix Angelicae Sinensis
1 part of 2 parts of Pericarpium Citri tangerinae of 3 parts of Cortex Dictamni of the Radix Paeoniae Alba
1 part of 1 part of Radix Saposhnikoviae of 2 parts of Fructus Kochiae of Radix Codonopsis.
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| CN101181612B (en) * | 2007-11-21 | 2010-09-22 | 李玉珍 | Medicament for curing cold urticaria |
| CN101874850B (en) * | 2009-04-30 | 2012-03-21 | 杨少梅 | Medicament for treating chronic urticaria |
| CN102973711A (en) * | 2012-12-16 | 2013-03-20 | 青岛汉河药业有限公司 | Traditional Chinese medicine decoction for treating urticaria |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1907378A (en) * | 2006-08-04 | 2007-02-07 | 胡彩芳 | Decoction preparation for treating QIXUELIANGXU type chronic urticaria and its preparation process |
| CN1907368A (en) * | 2006-08-04 | 2007-02-07 | 胡彩芳 | Decoction preparation for treating heat-toxin type chronic urticaria and its preparation process |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1907378A (en) * | 2006-08-04 | 2007-02-07 | 胡彩芳 | Decoction preparation for treating QIXUELIANGXU type chronic urticaria and its preparation process |
| CN1907368A (en) * | 2006-08-04 | 2007-02-07 | 胡彩芳 | Decoction preparation for treating heat-toxin type chronic urticaria and its preparation process |
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