CN101024095A - Sterilized magnesium sulfate dressing preparation - Google Patents
Sterilized magnesium sulfate dressing preparation Download PDFInfo
- Publication number
- CN101024095A CN101024095A CN 200710087101 CN200710087101A CN101024095A CN 101024095 A CN101024095 A CN 101024095A CN 200710087101 CN200710087101 CN 200710087101 CN 200710087101 A CN200710087101 A CN 200710087101A CN 101024095 A CN101024095 A CN 101024095A
- Authority
- CN
- China
- Prior art keywords
- magnesium sulfate
- dressing
- sterilized
- sterilization
- medical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to sterilized magnesium sulfate wet dressing agent. It is formed by medical using magnesium sulfate aqueous solution and carrier. The former accounts for 20-50wt%, and can be made by high temperature sterilizing after sand stick filtering with 0.50-0.80mum aperture. The latter can be the water absorption paper towel, gauze, or medical using dressing. It can be used to cure local subcutaneous tissue swelling ache. The using method includes the following steps: dressing it along the vein direction, changing for every 30-60min until to the dripping off, stopping the wet dressing after withdrawing the needle for 1-2h. The user can understand clearly through the direction for use on the packaging bag which can solve the problems of carryover, using inconvenient, and infection.
Description
The application requires on May 11st, 06, the priority of Chinese patent application numbers 200620026022.6.
Technical field
The invention belongs to field of medical technology, relate to and have the Wet-dressing agent that swollen effect is gone in antiinflammatory, a kind of sterilized magnesium sulfate dressing preparation of saying so more specifically is mainly used in the swelling pain that the treatment local subcutaneous tissue occurs.
Background technology
Clinically in the Chang Yong venous transfusion because negligent supervision easily causes non-aggressive medicine or corrosive medicine or solution to enter surrounding tissue causes and ooze out and exosmose, cause local subcutaneous tissue and swelling pain occurs, influence limb function, severe patient can cause cutaneous necrosis, increase the patient suffering, and cause easily conflicting of nursing staff and patient.Moisten compress therapy is meant with the gauze dip in liquid medicine and applies a kind of method that disease is treated in the affected part.This method has effects such as suppressing to ooze out, to restrain antipruritic, reducing swelling and alleviating pain, control infection, promotion skin healing.For many years, the soak gauze that Adlerika is soaked spreads on the affected part, adopted by vast doctor always, common way is that the doctor gives the patient with the Adlerika and the gauze that prepare, instrucion is folding with gauze, spreads on the affected part after soaking with Adlerika, will tell simultaneously when patient's gauze is pulled out from medicinal liquid, want twisting to get not do and wet, just right.Overdrying effect bad, the medicinal liquid cross flow of having wet excessively.This way needs the doctor to make detailed description and interpretation on the one hand, and the patient carries and use equal inconvenience on the other hand; The used Adlerika of what is more important, gauze, utensil etc. can not guarantee to operate under the environmental condition of cleaning, cause bacteria attack easily, cause the infection in affected part, have increased the weight of patient's misery.
Summary of the invention
The object of the present invention is to provide a kind of improved sterilized magnesium sulfate dressing preparation, it can overcome in the prior art because the defective that operational issue causes the bacteria attack affected part to infect.
Another object of the present invention has been to provide the using method of sterilized magnesium sulfate dressing preparation, makes the patient effectively prevent phlebitic generation in the treatment disease.
Why the inventor selects the main component of magnesium sulfate as reducing swelling and alleviating pain, be because magnesium sulfate can the antagonism calcium ion, usually magnesium sulfate is used as calcium ion antagonist and uses, and calcium ion is to participate in smooth muscle contraction, so magnesium sulfate can the vasodilator smooth muscle, since edema be because interstitial fluid too much due to, its tissue is pressed higher, and when smooth muscle relaxation, too much interstitial fluid can be along pressure current blood back pipe, edema will alleviate, its repercussive mechanism that Here it is.
For achieving the above object, the technical solution adopted in the present invention is: a kind of sterilized magnesium sulfate dressing preparation is characterized in that: it is made up of medicinal ingredient magnesium sulfate solution and medical carrier; Its medicinal ingredient magnesium sulfate solution is 20%-50% (weight), and adopting the aperture is the sand rod filtration back high temperature sterilize of 0.50-0.80 μ m; Medical carrier is selected high-hydroscopicity napkin, gauze or medical dressing for use.
The sterilized magnesium sulfate dressing preparation that contains variable concentrations of the present invention mainly is different with the reason that produces swelling at the degree of the intravenous injection medicinal liquid difference of using, swelling, determines to use the sterilized magnesium sulfate dressing preparation of various variable concentrations.Wherein said medicinal ingredient magnesium sulfate sterile water solution is generally 20%～50% (weight), is preferably 20%-45% (weight), is more preferably to adopt 25-33% (weight) magnesium sulfate sterile water solution.
The using method of sterilized magnesium sulfate dressing preparation of the present invention, a kind of is will contain 20%～50% sterilization sulphuric acid Wet-dressing agent to move towards soak along vein on the vein of injection in transfusion, per 30～60min changes once, drips off until medicine, pulls out pin 1～2h and stops soak.Another method is to adopt 20%～50% sterilization sulphuric acid Wet-dressing agent to add plastic protective film for plastics the part of swelling, and all parcel is opened the 20～30min that ventilates every 1h.
High-hydroscopicity napkin of the present invention, gauze or medical dressing are through 20%～50% Adlerika immersion treatment, tailor pack into behind sterilization plastic bag sealing packing of slabbing, and its detailed preparation method is as follows:
(1) with magnesium sulfate with after the water for injection dissolving, add proper amount of water for injection as requested and be configured to 20%; 25%; 33%; 45%; 50% medicinal liquid, medicinal liquid should be controlled at 5～7 through checking its content of dispersion, pH value, and medicinal liquid is with to be that the sand rod of 0.50～0.80 μ m filters standby in the aperture (above-mentioned production process should under the condition of 100,000 grades of cleanings).
(2) under the working condition of 10,000 grades of cleanings, will put into container as carrier through high-hydroscopicity napkin, gauze or the medical dressing of tailoring slabbing of sterilization treatment, add the medicinal liquid that is up to the standards and soak 30～60min, pack into and seal through in the high pressure resistant pyritous plastic bag of sterilization treatment.Put into the sterilization cabinet then, adopt 100 ℃ of steam sterilization 45～60min, promptly can be made into.And according to " Chinese Pharmacopoeia 2005 editions " two appendix sterility test methods, testing should be up to specification.
During use the sterilized magnesium sulfate dressing preparation sealing bags is taken apart, taken out the wetted high-hydroscopicity napkin of Adlerika, gauze or medical dressing sheet, can use, also can be used for hot compress or cold compress.In wrapper or packaging bag, also can be provided with sign and operation instruction, can make the patient be well understood to using method, solve the problem of carrying and use inconvenience and infection.
The present invention compares its distinguishing feature with the soak method that present hospital often adopts and is:
1 prescription is simple, adopts 20%～50% Adlerika to soak, in the condition production of clean environment through the scientific method high temperature sterilize.Select for use non-woven fabrics to make substrate, Transdermal absorption is more complete, the pharmaceutical quantities abundance, and by the siphonage Transdermal absorption, drug absorption is more complete, has avoided the first pass effect of endo-medicine liver.
2 antiinflammatory go to be swollen with imitate fast, Wet-dressing agent 10～20min basic absorption, strong osmotic, through focus has shortened administration time.The drug action time is long, and only need stick 3 every day, is erysipelas, phlebitis, hydrofluoric acid burn patient's desirable medication.
The Wet-dressing agent of 3 Adlerikas easy to use adopts low sensitivity high-hydroscopicity napkin, gauze or medical dressing to avoid irritated generation substantially, and the while is pollution clothes not, and is easy to use, guarantees carrying out smoothly of body infusion treatment.
4 used Adlerikas, gauzes are all produced through strict sterilization in the environmental condition of 100,000 grades of cleanings, at the environmental condition lower seal of 10,000 grades of cleanings, and have prevented the infection that the bacteria attack affected part is caused through sterilization treatment, have guaranteed patient's safe handling.
For the beneficial effect that further proves sterilized magnesium sulfate dressing preparation has carried out following contrast experiment:
Test one group: 20 routine patients with cerebrovascular disease were infused 7 days continuously, because transfusion time is long, particularly contained the mannitol that height oozes effect in the medicinal liquid, cause subcutaneous dropsy, show as local organization swelling, brought misery, brought difficulty also for venipuncture once more to the patient.At this moment the doctor often gives the patient with the Adlerika and the gauze that prepare, enjoin gauze to spread on the affected part after folding, and commentariess on classics of not getting better of 3 days rear section patient's symptoms, the low-grade infection symptom appears in 8 examples, 5 example initiation phlebitis.
Test two groups: the continuously transfusion 7 days of 20 routine patients with cerebrovascular disease, in transfusion, will contain 33% sterilization sulphuric acid Wet-dressing agent and move towards soak along vein on the vein of injection, per 30～60min changes once.Drip off until medicine, pull out pin 1～2h and stop soak.Result statistics, phlebitic incidence rate is reduced to 5% by original 40%, reduces phlebitic generation greatly.
Test three groups: for 20 routine patients with cerebrovascular disease; the local edema that causes is failed to treat timely severe swelling is taken place because medicinal liquid exosmoses in transfusion; add the local all parcel of plastic protective film for plastics in the time of soak 50% sterilized magnesium sulfate dressing preparation with swelling; each 3 hours, open ventilation 30min every 1h.One day 3 times, clinical effectiveness statistics, 90% patient was through 3 days treatment, and swelling pain is clearly better, and has obtained satisfied curative effect.
For the more effective therapeutic effect of proof sterilized magnesium sulfate dressing preparation of the present invention, it is as follows to have carried out its result of clinical trial:
Clinical data
(1) physical data
In certain hospital, select the department of cerebral surgery patient because the improper liquid that causes in the venous transfusion process of restlessness or PeV puncture position oozes out and exosmoses to subcutaneous patient's 80 examples, wherein ooze out 54 examples, 26 examples of exosmosing; Man's 56 examples, women 24 examples; 3 months～72 years old age.Be divided into each 40 example of matched group and experimental group in order at random.With reference to U.S. venous transfusion nurses association (INS) criterion assessment limb swelling situation, 1 grade of experimental group 4 example wherein, matched group 6 examples; Each 8 example of 2 grades of experimental grouies and matched group; 3 grades of experimental group 16 examples, matched group 14 examples; Each 12 example of 4 grades of experimental grouies and matched group.
(2) Therapeutic Method
All use 20%～50% Adlerika hot-wet compress for 2 groups.Method: will contain 20%～50% sterilized magnesium sulfate dressing preparation and move towards along vein, entirely spread on the swelling position, wrap up with plastic paper then, 50 ℃ of hot towel parcel plastic papers of external, the reuse plastic paper wraps up hot towel, treat that hot towel cools off hot-wet compress affected part again, time remaining 2h, every day 3 times.
(3) efficacy assessment standard
Produce effects: the swelling of treatment 1d subcutaneous tissue is disappeared fully, and the distending pain sense disappears, and it is normal that sensory perception recovers, activity freely, it is normal that skin elasticity is recovered;
Effectively: the swelling of treatment 2d subcutaneous tissue is disappeared fully, and the distending pain sense disappears, and it is normal that sensory perception recovers, and it is normal that skin elasticity is recovered;
Invalid: the swelling of treatment 3d subcutaneous tissue is disappeared not exclusively, and the distending pain sense exists, and sensory perception is blunt, and it is poor that skin elasticity is recovered.
(4) result: experimental group produce effects 36 examples, effective 4 examples; Matched group produce effects 14 examples, effective 10 examples, invalid 16 examples.The experimental group curative effect obviously is better than matched group (P＜0.05).
(5) discuss
Venous transfusion is the main means of treatment disease, and confusion, dysphoria patient, easily cause syringe needle to skid off blood vessel and cause liquid outward and ooze out and exosmose to subcutaneous tissue, cause limb swelling, particularly the contour sepage body of 20% mannitol solution and potassium ion liquid stimulates and can increase the weight of the local swelling limbs pain, swelling severe patient local skin occurs shinny, limbs are sent out cold, and stolidity influences limb function, bring very big misery for patient's body and mind, influence carrying out smoothly of body infusion treatment.In time use 20%～50% Adlerika hot-wet compress illing skin, mainly be to utilize the height of 20%～50% Adlerika to ooze the effect antiinflammatory to go to swell, add with plastic paper or hot water towel parcel, can make local limbs keep uniform temperature, promote the backflow of telangiectasis and blood, local limb swelling is disappeared, reach and alleviate the purpose that swells and ache.Clinical practice shows: 20%～50% Adlerika hot-wet compress is passable to 1～2 grade of swelling curative effect, and is relatively poor to 3～4 grades of curative effects, and it is long to alleviate the swelling time.
The specific embodiment
Below by the specific embodiment, foregoing of the present invention is described in further detail, embodiment only is indicative, means that never it limits the scope of the invention by any way.But do not breaking away under the above-mentioned technological thought situation of the present invention, the various replacements of making according to ordinary skill knowledge and habitual means or the modification of change include within the scope of the invention.
Embodiment 1
Under the working condition of 100,000 grades of cleanings, magnesium sulfate with after the water for injection dissolving, is added proper amount of water for injection as requested and is configured to 20%; 25%; 33%; 45; 50% medicinal liquid, medicinal liquid is qualified through the check content of dispersion; PH value is controlled at 5, and it is standby that medicinal liquid is with the aperture that the sand rod of 0.80 μ m filters the back.To put into container through the gauze of tailoring the slabbing work of sterilization treatment, qualified medicinal liquid soaks 60min to add the check content of dispersion, seal (pack and seal and under the condition of local 10,000 grades of cleanings, to finish) in the high pressure resistant pyritous plastic bag of the sterilization treatment of packing into, put into the sterilization cabinet then adopting 100 ℃ of steam sterilization 45min, promptly can be made into.
Embodiment 2
Under the working condition of 100,000 grades of cleanings, magnesium sulfate with after the water for injection dissolving, is added proper amount of water for injection as requested and is configured to 25%; 33% or 45% medicinal liquid, medicinal liquid are the sand rod filtration of 0.50 μ m with the aperture.PH value is controlled at 7, and medicinal liquid is standby through after the assay was approved.To put into container through the gauze of tailoring the slabbing work of sterilization treatment, qualified medicinal liquid soaks 30min to add the check content of dispersion, seals in the high pressure resistant pyritous plastic bag of packing into, puts into the sterilization cabinet then at 100 ℃ of steam sterilization 60min of employing, promptly can be made into.
Using method and effect:
(1) in beginning during quiet chemotherapeutics, will contain 33% sterilized magnesium sulfate dressing preparation and move towards along vein, entirely spread on the swelling position, drip off until chemotherapeutics, pull out pin 1～2h and stop soak.
(2) use 25% the local hot-wet compress of sterilized magnesium sulfate dressing preparation, entirely spread on the swelling position, each 30～60min, every day for several times, till detumescence.Severe struttuer, soak sulphuric acid Wet-dressing agent can add plastic protective film for plastics (as convenient bag), with local all parcels of swelling, opens the 20～30min that ventilates every 1h.Obtained satisfied curative effect for the local edema that causes of exosmosing at the transfusion herb liquid.
(3) the vein reaction takes place in about 87% patient behind the common intravenous injection navelbine.Existing 39 routine patients adopt 50% sterilized magnesium sulfate liquid Wet-dressing agent to spread on the skin of point of puncture proximal part vein trend, drip off complete back 15min until navelbine, do not have 1 example among the experimental result 39 routine patients phlebitis takes place, thereby alleviate patient's misery greatly, and improve its quality of life.
The present invention mainly comprises high-hydroscopicity napkin, gauze or the medical dressing sheet of the Adlerika immersion that will pack with plastic bag sealing through sterilization treatment, spread on patient's swelling pain position, solved and carried and used inconvenience, prevent bacteria attack, prevented the good effect that infect in the patient affected part.In addition as required, be provided with labelling and operation instruction in the wrapper of outer end or packaging bag, can make the patient be well understood to using method, the present invention can be prescribed to the patient by the doctor in hospital, also can be in pharmacy's retail.
Claims (7)
1, a kind of sterilized magnesium sulfate dressing preparation is characterized in that: it is made up of medicinal ingredient magnesium sulfate solution and medical carrier; Its medicinal ingredient magnesium sulfate solution is 20%-50% (weight), and adopting the aperture is the sand rod filtration back high temperature sterilize of 0.50-0.80 μ m; Medical carrier is selected high-hydroscopicity napkin, gauze or medical dressing for use.
2, sterilized magnesium sulfate dressing preparation as claimed in claim 1, wherein said medicinal ingredient magnesium sulfate solution are 20%-45% (weight).
3, sterilized magnesium sulfate dressing preparation as claimed in claim 1, wherein said medicinal ingredient magnesium sulfate solution are 25%-33% (weight).
4, sterilized magnesium sulfate dressing preparation as claimed in claim 1, wherein said high-hydroscopicity napkin, gauze or medical dressing are through 20%-50% Adlerika immersion treatment, tailor pack into behind sterilization plastic bag sealing packing of slabbing.
5, a kind of method for preparing claim 1-4 sterilized magnesium sulfate dressing preparation is characterized in that:
(1) under the condition of 100,000 grades of cleanings, magnesium sulfate is configured to the magnesium sulfate medicinal liquid in proportion with after the water for injection dissolving, the control pH value is 5～7, and medicinal liquid is that the sand rod filtration of 0.50～0.80 μ m is standby with the aperture after checking its content of dispersion;
(2) under the working condition of 10,000 grades of cleanings, will put into container as carrier through high-hydroscopicity napkin, gauze or the medical dressing of tailoring slabbing of sterilization treatment, add the medicinal liquid that is up to the standards and soak 30～60min, pack into and seal through in the high pressure resistant pyritous plastic bag of sterilization treatment, put into the sterilization cabinet then, adopt 100 ℃ of steam sterilization 45～60min, promptly can be made into.
6, the using method of the described sterilized magnesium sulfate dressing preparation of a kind of claim 1, it is characterized in that, the sterilization sulphuric acid Wet-dressing agent that will contain 20-50% in transfusion moves towards soak on the vein of injection along vein, per 30～60min changes once, drip off until medicine, pull out pin 1～2h and stop soak.
7, the using method of the described sterilized magnesium sulfate dressing preparation of a kind of claim 1 is characterized in that adopting the sterilization sulphuric acid Wet-dressing agent of 20-50% to add plastic protective film for plastics the part of swelling, and all parcel is opened the 20～30min that ventilates every 1h.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2007100871017A CN100540067C (en) | 2006-05-11 | 2007-03-21 | Sterilized magnesium sulfate dressing preparation |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200620026022 | 2006-05-11 | ||
| CN200620026022.6 | 2006-05-11 | ||
| CNB2007100871017A CN100540067C (en) | 2006-05-11 | 2007-03-21 | Sterilized magnesium sulfate dressing preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101024095A true CN101024095A (en) | 2007-08-29 |
| CN100540067C CN100540067C (en) | 2009-09-16 |
Family
ID=38742936
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2007100871017A Expired - Fee Related CN100540067C (en) | 2006-05-11 | 2007-03-21 | Sterilized magnesium sulfate dressing preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100540067C (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102631697A (en) * | 2012-05-10 | 2012-08-15 | 贾国平 | Preparation and test method of magnesium sulfate dried piece |
| CN102688521A (en) * | 2012-06-12 | 2012-09-26 | 汪六一 | Potato and magnesium sulfate composition wet compressing bag |
| CN103127168A (en) * | 2013-03-18 | 2013-06-05 | 贾国平 | Hydropathic compress paste containing magnesium sulfate as well as preparation method and application of paste |
| CN104382930A (en) * | 2014-10-27 | 2015-03-04 | 袁继美 | Liquid medicine for treating mannitol infusion leakage |
| CN105288633A (en) * | 2015-03-02 | 2016-02-03 | 天津瑞安医药科技发展有限公司 | Compound magnesium sulfate wet compress and preparation method thereof |
| CN107468704A (en) * | 2017-09-14 | 2017-12-15 | 上海市第十人民医院 | Application of the magnesium sulfate in soft tissue swelling disease and its eye mask patch containing magnesium sulfate |
-
2007
- 2007-03-21 CN CNB2007100871017A patent/CN100540067C/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102631697A (en) * | 2012-05-10 | 2012-08-15 | 贾国平 | Preparation and test method of magnesium sulfate dried piece |
| CN102688521A (en) * | 2012-06-12 | 2012-09-26 | 汪六一 | Potato and magnesium sulfate composition wet compressing bag |
| CN103127168A (en) * | 2013-03-18 | 2013-06-05 | 贾国平 | Hydropathic compress paste containing magnesium sulfate as well as preparation method and application of paste |
| CN104382930A (en) * | 2014-10-27 | 2015-03-04 | 袁继美 | Liquid medicine for treating mannitol infusion leakage |
| CN105288633A (en) * | 2015-03-02 | 2016-02-03 | 天津瑞安医药科技发展有限公司 | Compound magnesium sulfate wet compress and preparation method thereof |
| CN107468704A (en) * | 2017-09-14 | 2017-12-15 | 上海市第十人民医院 | Application of the magnesium sulfate in soft tissue swelling disease and its eye mask patch containing magnesium sulfate |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100540067C (en) | 2009-09-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100540067C (en) | Sterilized magnesium sulfate dressing preparation | |
| CN105748315B (en) | A kind of composition for repairing skin barrier | |
| CN103127168A (en) | Hydropathic compress paste containing magnesium sulfate as well as preparation method and application of paste | |
| CN102302678A (en) | Skin membrane repair drug | |
| CN101366968A (en) | Compound magnesium sulfate wet-dressing agent and preparation method thereof | |
| CN208641524U (en) | A kind of Adlerika soak packet | |
| CN102716281A (en) | Care solution for cleaning wounds after operation | |
| CN101028365B (en) | Medicine for treating burn and ambustion and its production | |
| CN104706777A (en) | Traditional Chinese medicine narcotic analgesic for treating hip replacement postoperation pain | |
| CN101596242A (en) | Pure disinfection of Chinese drug treatment liquid | |
| CN108815182B (en) | Sterilized compound magnesium sulfate wet-dressing composition as well as preparation method and application thereof | |
| CN102058618A (en) | Emla magnesium sulfate wet dressing agent and preparation method thereof | |
| CN100584375C (en) | Formula for treating scar | |
| CN203017191U (en) | Sterile self-adhesive intravenous wet-dressing patch | |
| CN101579307A (en) | Application of hypertonic injection to preparation of medicament accelerating wound healing | |
| CN108635362A (en) | A kind of pharmaceutical composition for treating diabetes | |
| CN100381137C (en) | Wound repairing and burns treating cream | |
| CN109303773A (en) | A kind of postoperative wound care thimerosal | |
| CN206934244U (en) | A kind of medical vein cold compress dressing patch | |
| CN105853651A (en) | Traditional Chinese medicine ointment for local anesthetic and analgesic, as well as preparation method and application thereof | |
| CN207412449U (en) | Infusion paste | |
| CN1141967C (en) | Externally applied Chinese medicine oil prepn for treating burns and scalds | |
| CN201379657Y (en) | Single-use hemodialysis arterial venous internal fistula puncture kit | |
| CN201033175Y (en) | Sterilizing magnesium sulfate moisture-applying tablet | |
| CN116747207A (en) | Magnesium sulfate breast wet-dressing |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Free format text: FORMER OWNER: JIA ZHENGZHENG |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20100406 Address after: 300113, room 1, gate 2, building 6, Kangding, Yibin Road, Tianjin, Nankai District Patentee after: Jia Guoping Address before: 300113, room 1, gate 2, building 6, Kangding, Yibin Road, Tianjin, Nankai District Co-patentee before: Jia Zhengxi Patentee before: Jia Guoping |
|
| ASS | Succession or assignment of patent right |
Owner name: TIANJIN HEIWEIYIJIA MEDICAL SUPPLIES CO., LTD Free format text: FORMER OWNER: JIA GUOPING Effective date: 20100723 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 300113 ROOM 6, UNIT 1, BUILDING 2, KANGDINGLI, YIBINDAO, NANKAI DISTRICT, TIANJIN CITY TO: 300402 INDUSTRY ZONE, YIXINGBUSAN STREET, BEICHEN DISTRICT, TIANJIN CITY |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20100723 Address after: 300402 Beichen District, Yixing District, Tianjin port three Street Industrial Zone Patentee after: Tianjin Haiwei Yijia Medical Article Co., Ltd. Address before: 300113, room 1, gate 2, building 6, Kangding, Yibin Road, Tianjin, Nankai District Patentee before: Jia Guoping |
|
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20090916 Termination date: 20170321 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |