CN109303773A - A kind of postoperative wound care thimerosal - Google Patents

A kind of postoperative wound care thimerosal Download PDF

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Publication number
CN109303773A
CN109303773A CN201810773690.2A CN201810773690A CN109303773A CN 109303773 A CN109303773 A CN 109303773A CN 201810773690 A CN201810773690 A CN 201810773690A CN 109303773 A CN109303773 A CN 109303773A
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parts
thimerosal
wound
wound care
postoperative wound
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CN201810773690.2A
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Chinese (zh)
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高霞
胡南南
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Individual
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Priority to CN201810773690.2A priority Critical patent/CN109303773A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/345Nitrofurans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/075Ethers or acetals
    • A61K31/085Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/375Ascorbic acid, i.e. vitamin C; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/722Chitin, chitosan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/82Theaceae (Tea family), e.g. camellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a kind of postoperative wound care thimerosal, by the material composition of following parts by weight, 5-10 parts of ethyl alcohol, 8-10 parts of tea polyphenols, 2-6 parts of carboxylic butyl chitosan, 10-20 parts of ascorbic acid, 1-2 parts of Phenoxyethanol, 4-6 parts of furacilin solution;It takes above-mentioned each component to be uniformly mixed, obtains this thimerosal.The present invention has the following technical effects by adopting the above technical scheme, can prevent wound infection, promotes wound healing, and analgesic is antipruritic.

Description

A kind of postoperative wound care thimerosal
Technical field
The present invention relates to field of medical technology, and in particular to a kind of postoperative wound care thimerosal.
Background technique
Surgery cut infection is one of most common postoperative complication of surgery patients, and surgery cut infection is be easy to cause Patient wound's poor healing extends the hospital stays, increases the pain and financial burden of patient, it is serious possibly even can be with next life Critically ill danger.Clinically operative incision often is reduced in terms of sterile working, hand Postoperative Dressing this these three from Preoperative Method, operation Infection rate.
Surgery cut infection is divided into pyogenic infection and specific infection, and pyogenic infection is special caused by general pyogenic baeceria Opposite sex infection has special clinical characters caused by special germ.Principle of reatment is the cause of disease of infection to be eliminated, and removes purulence Liquid and necrotic tissue increase the anti-infective and repair ability of patient.
The drug of existing clinical treatment surgical infection is mainly antibiotic medicine and Chinese medicine, takes antibiotic to dosage and treatment Cheng Jun there are certain requirements, and Time of Administration is unsuitable too long, and effect is poor, toxic side effect is big, or even can not be restored.Existing treatment surgery The traditional Chinese medicine ingredients of infection are complicated, it is slower to take effect, and effect is not obvious enough.
The patent of invention that number of patent application is 201210084084.2 discloses a kind of wound infection after surgical operation for the treatment of Drug, including 40-60 parts of Radix Angelicae Sinensis 40- of ciliate desert-grass, 60 parts of elephant hides 30-50 parts of pearls of 20-45 parts of phoenix clothings 25-50 parts of blood of powder more than 15-30 portions of 35-55 parts of Radix Et Rhizoma Rheis, 30-50 parts of Radix Notoginseng of 15-30 portions of radix scrophulariae 10-20 parts 5-2 parts of borneol of 25 parts of myrrhs of red halloysite 15-.Above scheme has no toxic side effect, cheap, treatment Speed is fast, and curative effect is reliable, and prescription linking closely corruption mentions poison, activating microcirculation and removing stasis medicinal, promoting granulation and wound healing, and sequelae is not stayed in blood-enrich.On but It states drug and does not promote wound healing, relieve pain, antipruritic effect.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of postoperative wound care thimerosal, can prevent from hurting
Mouthfeel dye, promotes wound healing, and analgesic is antipruritic.
In order to solve the above technical problems, the present invention uses following technical scheme, a kind of postoperative wound care thimerosal is special Sign is being: by the material composition of following parts by weight, 5-10 parts of ethyl alcohol, 8-10 parts of tea polyphenols, 2-6 parts of carboxylic butyl chitosan resists Bad hematic acid 10-20 parts, 1-2 parts of Phenoxyethanol, 4-6 parts of furacilin solution;It takes above-mentioned each component to be uniformly mixed, obtains this disinfection Liquid.
It is further improvement of the present invention below:
The nursing thimerosal, by the material composition of following parts by weight, 8 parts of ethyl alcohol, 9 parts of tea polyphenols, 5 parts of carboxylic butyl chitosan, 15 parts of ascorbic acid, 1.5 parts of Phenoxyethanol, 5 parts of furacilin solution.
The present invention has the following technical effects by adopting the above technical scheme, can prevent wound infection, promotes wound healing, Analgesic, it is antipruritic.
Specific embodiment
Embodiment 1, a kind of postoperative wound care thimerosal, 5-10 parts of ethyl alcohol, 8-10 parts of tea polyphenols, carboxylic butyl chitosan 2-6 parts, 10-20 parts of ascorbic acid, 1-2 parts of Phenoxyethanol, 4-6 parts of furacilin solution.It takes above-mentioned each component to be uniformly mixed, obtains This thimerosal.
Usage: going above-mentioned thimerosal wiping in wound, and three times, wiping can fully recover for 3 days for wiping daily.
In clinical observation, postoperative wound care thimerosal of the invention has more apparent effect for wound healing, can Every bacterium, antibacterial promotion wound healing, but can prevent with wound adhesion, analgesic, it is antipruritic, use patient one after wound care liquid dressing Reflection is caused to be comfortable on, without pain is small to wound stimulation, and clearly, surface of a wound exudate significantly reduces, and the surface of a wound does not give an offensive smell, gas Taste faint scent.
Embodiment 2, a kind of postoperative wound care thimerosal, 8 parts of ethyl alcohol, 9 parts of tea polyphenols, 5 parts of carboxylic butyl chitosan is anti-bad 15 parts of hematic acid, 1.5 parts of Phenoxyethanol, 5 parts of furacilin solution.It takes above-mentioned each component to be uniformly mixed, obtains this thimerosal.
Usage: going above-mentioned thimerosal wiping in wound, and three times, wiping can fully recover for 3 days for wiping daily.
In clinical observation, postoperative wound care thimerosal of the invention has more apparent effect for wound healing, can Every bacterium, antibacterial promotion wound healing, but can prevent with wound adhesion, analgesic, it is antipruritic, use patient one after wound care liquid dressing Reflection is caused to be comfortable on, without pain is small to wound stimulation, and clearly, surface of a wound exudate significantly reduces, and the surface of a wound does not give an offensive smell, gas Taste faint scent.
Embodiment 3, a kind of postoperative wound care thimerosal, 10 parts of ethyl alcohol, 10 parts of tea polyphenols, 6 parts of carboxylic butyl chitosan resists 20 parts of bad hematic acid, 2 parts of Phenoxyethanol, 6 parts of furacilin solution.It takes above-mentioned each component to be uniformly mixed, obtains this thimerosal.
Usage: going above-mentioned thimerosal wiping in wound, and three times, wiping can fully recover for 3 days for wiping daily.
In clinical observation, postoperative wound care thimerosal of the invention has more apparent effect for wound healing, can Every bacterium, antibacterial promotion wound healing, but can prevent with wound adhesion, analgesic, it is antipruritic, use patient one after wound care liquid dressing Reflection is caused to be comfortable on, without pain is small to wound stimulation, and clearly, surface of a wound exudate significantly reduces, and the surface of a wound does not give an offensive smell, gas Taste faint scent.

Claims (2)

1. a kind of postoperative wound care thimerosal, feature are being: by the material composition of following parts by weight, 5-10 parts of ethyl alcohol, 8-10 parts of tea polyphenols, 2-6 parts of carboxylic butyl chitosan, 10-20 parts of ascorbic acid, 1-2 parts of Phenoxyethanol, furacilin solution 4-6 Part;It takes above-mentioned each component to be uniformly mixed, obtains this thimerosal.
2. postoperative wound care thimerosal according to claim 1, feature are being: the nursing
Thimerosal, by the material composition of following parts by weight, 8 parts of ethyl alcohol, 9 parts of tea polyphenols, 5 parts of carboxylic butyl chitosan, ascorbic acid 15 parts, 1.5 parts of Phenoxyethanol, 5 parts of furacilin solution.
CN201810773690.2A 2018-07-15 2018-07-15 A kind of postoperative wound care thimerosal Pending CN109303773A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810773690.2A CN109303773A (en) 2018-07-15 2018-07-15 A kind of postoperative wound care thimerosal

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810773690.2A CN109303773A (en) 2018-07-15 2018-07-15 A kind of postoperative wound care thimerosal

Publications (1)

Publication Number Publication Date
CN109303773A true CN109303773A (en) 2019-02-05

Family

ID=65226016

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810773690.2A Pending CN109303773A (en) 2018-07-15 2018-07-15 A kind of postoperative wound care thimerosal

Country Status (1)

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CN (1) CN109303773A (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105287743A (en) * 2015-11-09 2016-02-03 柳青青 Sterilization disinfectant formula for nursing
CN106619708A (en) * 2016-11-17 2017-05-10 郑州郑先医药科技有限公司 Disinfectant for wound disinfection
CN107875146A (en) * 2017-11-07 2018-04-06 颜强 A kind of anti-inflammation medicament

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105287743A (en) * 2015-11-09 2016-02-03 柳青青 Sterilization disinfectant formula for nursing
CN106619708A (en) * 2016-11-17 2017-05-10 郑州郑先医药科技有限公司 Disinfectant for wound disinfection
CN107875146A (en) * 2017-11-07 2018-04-06 颜强 A kind of anti-inflammation medicament

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Application publication date: 20190205