CN101014622B - 用于检测分枝杆菌感染的富集抗体，应用方法和应用其的诊断检测 - Google Patents

用于检测分枝杆菌感染的富集抗体，应用方法和应用其的诊断检测 Download PDF

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Publication number
CN101014622B
CN101014622B CN200580029939XA CN200580029939A CN101014622B CN 101014622 B CN101014622 B CN 101014622B CN 200580029939X A CN200580029939X A CN 200580029939XA CN 200580029939 A CN200580029939 A CN 200580029939A CN 101014622 B CN101014622 B CN 101014622B
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China
Prior art keywords
antibodies
lam
enriched
antigen
mycobacterial
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Chinese (zh)
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CN101014622A (zh
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V·A·库尔钦
E·V·莫洛科娃
J·L·克里克
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Chemogen Inc
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Chemogen Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1289—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Mycobacteriaceae (F)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN200580029939XA 2004-07-20 2005-07-20 用于检测分枝杆菌感染的富集抗体，应用方法和应用其的诊断检测 Expired - Fee Related CN101014622B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58941904P 2004-07-20 2004-07-20
US60/589,419 2004-07-20
PCT/US2005/025875 WO2006012413A1 (en) 2004-07-20 2005-07-20 Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same

Publications (2)

Publication Number Publication Date
CN101014622A CN101014622A (zh) 2007-08-08
CN101014622B true CN101014622B (zh) 2011-12-28

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CN200580029939XA Expired - Fee Related CN101014622B (zh) 2004-07-20 2005-07-20 用于检测分枝杆菌感染的富集抗体，应用方法和应用其的诊断检测

Country Status (15)

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US (3) US7335480B2 (enExample)
EP (1) EP1771475B1 (enExample)
JP (1) JP4948402B2 (enExample)
CN (1) CN101014622B (enExample)
AP (1) AP2316A (enExample)
AT (1) ATE500272T1 (enExample)
AU (1) AU2005267111B2 (enExample)
BR (1) BRPI0513596B8 (enExample)
CA (1) CA2574432C (enExample)
DE (1) DE602005026665D1 (enExample)
EA (1) EA013228B1 (enExample)
MX (1) MX2007000916A (enExample)
UA (1) UA92721C2 (enExample)
WO (1) WO2006012413A1 (enExample)
ZA (1) ZA200700525B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006012413A1 (en) 2004-07-20 2006-02-02 Chemogen, Inc. Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same
WO2008067497A2 (en) * 2006-11-29 2008-06-05 Chemogen, Inc. Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same
US20100317037A1 (en) * 2009-06-16 2010-12-16 Sina Biotechnical Co. Detection of Mycobacterium Tuberculosis Bacilli
EP2668207A4 (en) 2011-01-24 2015-06-10 Univ Singapore MANNOSE-CAPTURED LIPOARABINOMANANE ANTIGEN-BINDING PROTEINS OBTAINED FROM ILLNESSIFYING MYCOBACTERIES
US10729771B2 (en) 2016-02-10 2020-08-04 Rutgers, The State University Of New Jersey Anti-LAM and anti-PIM6/LAM monoclonal antibodies for diagnosis and treatment of Mycobacterium tuberculosis infections
US10837962B2 (en) 2017-12-20 2020-11-17 General Electric Company Method and associated device for rapid detection of target biomolecules with enhanced sensitivity
US10830760B2 (en) 2017-12-20 2020-11-10 General Electric Company Device for rapid detection of tuberculosis-lipoarabinomannan (TB-LAM) with enhanced sensitivity
US20210302424A1 (en) * 2018-07-19 2021-09-30 Rutgers, The State University Of New Jersey Methods for dual detection and differentiation of infection by mycobacterium tuberculosis complex and nontuberculous mycobacteria
CN112639472A (zh) 2018-08-31 2021-04-09 富士胶片株式会社 免疫层析试剂盒及结核菌的检测方法
CN111234026A (zh) * 2020-02-21 2020-06-05 首都医科大学附属北京胸科医院 特异性结合脂阿拉伯甘露聚糖的单克隆抗体及其在分枝杆菌检测中的应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1423892A (en) * 1991-02-12 1992-09-07 Colorado State University Research Foundation Monoclonal antibodies directed towards mycobacterial antigens
US6214789B1 (en) 1993-03-12 2001-04-10 Xoma Corporation Treatment of mycobacterial diseases by administration of bactericidal/permeability-increasing protein products
US5756327A (en) 1994-09-13 1998-05-26 Cubist Pharmaceuticals, Inc. Recombinant mycobacterial isoleucyl-tRNA synthetase genes, tester strains and assays
AU1750197A (en) 1996-01-17 1997-08-11 Trustees Of Boston University Mycobacterium antigens and methods for their detection
GB9605083D0 (en) * 1996-03-11 1996-05-08 Royal Ordnance Plc Howitzer anchor spade
SE9600949D0 (sv) * 1996-03-12 1996-03-12 Stefan Svenson Method of diagnosing a mycobacterial disease and immunoassay kit
US6545130B2 (en) * 1997-06-04 2003-04-08 Albert Einstein College Of Medicine Of Yeshiva University Monoclonal antibodies to mycobacterium tuberculosis and a modified ELISA assay
WO2001064237A1 (en) * 2000-03-01 2001-09-07 Binax, Inc. Method for detecting the presence of target bacteria or a target component carbohydrate antigen thereof
US20040038201A1 (en) 2002-01-22 2004-02-26 Whitehead Institute For Biomedical Research Diagnostic and therapeutic applications for biomarkers of infection
WO2006012413A1 (en) 2004-07-20 2006-02-02 Chemogen, Inc. Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same
WO2008067497A2 (en) 2006-11-29 2008-06-05 Chemogen, Inc. Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Britton W J et al.Separate antigenic determinants on cell wallassociatedcarbohydrate antigens of mycobacterium lepraedefined withmonoclonal antibodies.International Journal of Leprosy and Other Mycobacterial Diseases54 4.1986,54(4),545-555.
Britton W J et al.Separate antigenic determinants on cell wallassociatedcarbohydrate antigens of mycobacterium lepraedefined withmonoclonal antibodies.International Journal of Leprosy and Other Mycobacterial Diseases54 4.1986,54(4),545-555. *
Schwebach J R et al.Expression of a mycobacterium tuberculosis arabinomananantigen in vitro and in vivo.Infection and Immunity69 9.2001,69(9),5671-5678.
Schwebach J R et al.Expression of a mycobacterium tuberculosis arabinomananantigen in vitro and in vivo.Infection and Immunity69 9.2001,69(9),5671-5678. *

Also Published As

Publication number Publication date
BRPI0513596B1 (pt) 2018-02-06
EP1771475A1 (en) 2007-04-11
EA200700345A1 (ru) 2007-08-31
JP4948402B2 (ja) 2012-06-06
US20100210823A1 (en) 2010-08-19
UA92721C2 (ru) 2010-12-10
US8057797B2 (en) 2011-11-15
DE602005026665D1 (de) 2011-04-14
AP2316A (en) 2011-11-04
ZA200700525B (en) 2008-09-25
AU2005267111A1 (en) 2006-02-02
US7615222B2 (en) 2009-11-10
WO2006012413A1 (en) 2006-02-02
JP2008507544A (ja) 2008-03-13
US20080213806A1 (en) 2008-09-04
BRPI0513596B8 (pt) 2021-07-27
EA013228B1 (ru) 2010-04-30
AP2007003884A0 (en) 2007-02-28
CA2574432A1 (en) 2006-02-02
ATE500272T1 (de) 2011-03-15
CN101014622A (zh) 2007-08-08
EP1771475B1 (en) 2011-03-02
CA2574432C (en) 2015-05-26
MX2007000916A (es) 2007-07-09
US7335480B2 (en) 2008-02-26
BRPI0513596A (pt) 2008-05-13
AU2005267111B2 (en) 2011-03-03
US20060127406A1 (en) 2006-06-15

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