CN100558410C - 调节凋亡的核酸,多肽,以及方法 - Google Patents

调节凋亡的核酸,多肽,以及方法 Download PDF

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Publication number
CN100558410C
CN100558410C CNB038161540A CN03816154A CN100558410C CN 100558410 C CN100558410 C CN 100558410C CN B038161540 A CNB038161540 A CN B038161540A CN 03816154 A CN03816154 A CN 03816154A CN 100558410 C CN100558410 C CN 100558410C
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China
Prior art keywords
apoptosis
cells
eif
rat
phm6
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Expired - Fee Related
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CNB038161540A
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English (en)
Chinese (zh)
Other versions
CN1741820A (zh
Inventor
C·泰勒
T·-W·王
L·佩特罗夫
J·C·卡尔森
R·纳拉延辛
J·E·汤姆普森
D·克利彻
M·考普
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Eloxx Pharmaceuticals Inc
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Senesco Technologies Inc
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Priority claimed from US10/141,647 external-priority patent/US7166467B2/en
Application filed by Senesco Technologies Inc filed Critical Senesco Technologies Inc
Publication of CN1741820A publication Critical patent/CN1741820A/zh
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Publication of CN100558410C publication Critical patent/CN100558410C/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CNB038161540A 2002-05-07 2003-05-07 调节凋亡的核酸,多肽,以及方法 Expired - Fee Related CN100558410C (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/141,647 US7166467B2 (en) 2001-07-23 2002-05-07 Nucleic acids, polypeptides, compositions, and methods for modulating apoptosis
US10/141,647 2002-05-07
US10/200,148 2002-07-23

Publications (2)

Publication Number Publication Date
CN1741820A CN1741820A (zh) 2006-03-01
CN100558410C true CN100558410C (zh) 2009-11-11

Family

ID=36093912

Family Applications (1)

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CNB038161540A Expired - Fee Related CN100558410C (zh) 2002-05-07 2003-05-07 调节凋亡的核酸,多肽,以及方法

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JP (1) JP4754819B2 (enExample)
CN (1) CN100558410C (enExample)
IL (1) IL198348A0 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR057234A1 (es) * 2005-12-13 2007-11-21 Senesco Technologies Inc Uso de eif-5a para destruir celulas de meiloma multiple
WO2009144933A1 (ja) * 2008-05-27 2009-12-03 国立大学法人東京大学 アポトーシス誘導薬
CN114231551B (zh) * 2021-12-24 2023-09-29 云南大学 蛋白在促进昆虫淋巴细胞凋亡和/或防治害虫中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1173897A (zh) * 1995-02-13 1998-02-18 诺瓦蒂斯有限公司 真核起始因子5A(eIF－5A)突变体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999001551A2 (en) * 1997-06-30 1999-01-14 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Novel inhibitor of cellular proliferation
US6538182B1 (en) * 1999-07-06 2003-03-25 Senesco, Inc. DNA encoding a plant deoxyhypusine synthase, a plant eukaryotic initiation factor 5A, transgenic plants and a method for controlling senescence programmed and cell death in plants
WO2001010906A1 (en) * 1999-08-06 2001-02-15 Pharmacia & Upjohn Company Crystallization and structure determination of staphylococcus aureus elongation factor p

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1173897A (zh) * 1995-02-13 1998-02-18 诺瓦蒂斯有限公司 真核起始因子5A(eIF－5A)突变体

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Deoxyhypusine synthase from rat testis:purification andcharacterization. WOLFF等人.Journal of Biological Chemistry,Vol.270 No.15. 1995 *
Sequence determination and cDNA cloningofeukaryoticinitiation factor 4D,the hypusine-containingprotein. Smit-McBride Z等人.J Biol Chem,Vol.264 No.3. 1989 *

Also Published As

Publication number Publication date
JP4754819B2 (ja) 2011-08-24
CN1741820A (zh) 2006-03-01
IL198348A0 (en) 2011-07-31
HK1088824A1 (zh) 2006-11-17
JP2005524410A (ja) 2005-08-18

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