CN100542545C - A kind of preparation method of natural astaxanthin and fishliver oil - Google Patents
A kind of preparation method of natural astaxanthin and fishliver oil Download PDFInfo
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- CN100542545C CN100542545C CNB2007100676616A CN200710067661A CN100542545C CN 100542545 C CN100542545 C CN 100542545C CN B2007100676616 A CNB2007100676616 A CN B2007100676616A CN 200710067661 A CN200710067661 A CN 200710067661A CN 100542545 C CN100542545 C CN 100542545C
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Abstract
A kind of preparation method of natural astaxanthin and fishliver oil; it is characterized in that this capsular raw material and parts by weight are 0.5～10 part of natural astaxanthin; 1～85 part of bathypelagic fish liver oil; natural astaxanthin oil effective content is 0.5～10%; 0.1～1 part of natural Vitamin E; press the composition proportioning; cod-liver oil is placed reactor; be heated to 50～60 ℃, natural astaxanthin is slowly joined in the reactor, add natural Vitamin E again; stirred 0.5～1 hour; become miscella, behind the microgranule and antibacterial in the elimination miscella, enter automatic soft capsule granulator and make capsule.With prior art relatively, advantage of the present invention is: collect making a concerted effort of above-mentioned three kinds of Natural antioxidants, have the non-oxidizability of extra-heavy, can efficiently strengthen body immunity, have good physiology and bioactive functions; Without any side effects and the toxicity to human body; Natural astaxanthin and the vitamin E dissolubility in cod-liver oil is greater than 99.5%, as easy as rolling off a log being absorbed by the body; The capsular shelf-life extended to more than 1 year from 6 months.
Description
Technical field
The present invention relates to a kind of health preparation and process technology thereof, particularly a kind of preparation method of natural astaxanthin and fishliver oil.
Background technology
Astaxanthin is called 3,3 '-dihydroxy-4,4 '-diketo-β, β '-carotene, molecular formula C
40H
52O
4, molecular weight 596.86, pinkiness is a kind of fat-soluble carotenoid.Astaxanthin has many important physical and biological functions such as non-oxidizability, antitumor and enhancing immunity, its non-oxidizability is 500～1000 times of vitamin E, be 10 times of carotene, it is the powerful antioxidant of aquatic animal, can suppress the formation of senile plaque, ophthalmic diseases, cardiovascular disease and rheumatoid arthritis are also had mitigation; Astaxanthin improves significantly to video display terminal operator visual fatigue tool, also helps to eliminate the physical discomfort that produces because of the time difference, and its effect is also more obvious than melatonin commonly used.So astaxanthin has important nutritive value and health-care effect.Can not be synthesized by human body but astaxanthin is the same with vitamin, can only from food, absorb.
As everyone knows, bathypelagic fish liver oil main component is vitamin A and vitamin D, and be rich in DHA, and DHA is the important nutrient of the promotion brain development of generally acknowledging, the bathypelagic fish liver oil is rich in natural immunity material epoxy radicals liver oil AKG5 simultaneously, effect is strong skeleton, help the absorption of calcium, promote skeleton calcification function, complete vision and epithelial cell are played an important role, can improve the resistance against diseases of concentration, enhancing body and the respiratory system of serum immune globulin I gG and I gM, effectively mediator's body immunity function, enhancing immunity rapidly.
Natural Vitamin E has very strong resistance to oxidation; can stop cellular oxidation damage, delaying human body cell chromosome fission process, keep cell function complete, prolong cell survival, delaying human body caducity; can protect simultaneously the decline after astaxanthin is subjected to light, improve the capsular shelf-life.
Summary of the invention
The preparation method that the purpose of this invention is to provide a kind of natural astaxanthin and fishliver oil, with astaxanthin or astaxanthin oil, bathypelagic fish liver oil, vitamin E is raw material, make capsule with good health care, being fit to all kinds of crowds uses, effect is remarkable, after adding vitamin E, can be prolonged more than one times the shelf-life of natural astaxanthin and fishliver oil.
A kind of preparation method of natural astaxanthin and fishliver oil is characterized in that adopting being prepared as follows step:
A) this capsular raw material and parts by weight are 0.5～10 part of natural astaxanthin, 1～85 part of bathypelagic fish liver oil, 0.1～1 part of natural Vitamin E, by above-mentioned proportioning components, the bathypelagic fish liver oil is placed reactor, be heated to 50～60 ℃, slowly join natural astaxanthin in the reactor, add natural Vitamin E again, stirring became miscella in 0.5～1 hour;
B) miscella is cooled to 30 ℃, adopts microgranule and antibacterial in the membrane ultrafiltration device elimination miscella;
C) filterable miscella enters automatic soft capsule granulator, makes natural astaxanthin and fishliver oil, and packing.
The raw material of natural astaxanthin and fishliver oil and parts by weight are 5 parts of natural astaxanthin oil, 45 parts of bathypelagic fish liver oils, 0.5 part of natural Vitamin E.
The parts by weight of natural astaxanthin are meant the natural astaxanthin parts by weight that are present in the natural astaxanthin oil; When directly being raw material with natural astaxanthin oil, according to the concentration of natural astaxanthin in the natural astaxanthin oil, the addition of natural astaxanthin oil is determined in the back of converting.
With prior art relatively, advantage of the present invention is: 1) the making a concerted effort of the above-mentioned three kinds of Natural antioxidants of collection, action compensating, have the non-oxidizability of extra-heavy, and can efficiently strengthen body immunity, have good physiology and bioactive functions; 2) adopt natural materials to form the without any side effects and toxicity to human body, no drug dependence; 3) natural astaxanthin and the vitamin E dissolubility in cod-liver oil is greater than 99.5%, as easy as rolling off a log being absorbed by the body; 4) added vitamin E in the capsule, the shelf-life extended to more than 1 year from 6 months, because natural astaxanthin is if be heated for a long time, or be subjected to ultraviolet light, infrared light to shine easy oxidation, only need to add PPm level vitamin E, can effectively suppress astaxanthin oxidation and decay, extend the shelf life.
The specific embodiment
Embodiment 1:
A kind of preparation method of natural astaxanthin and fishliver oil, it is characterized in that adopting and be prepared as follows step: A) this capsular raw material and parts by weight are 10 parts of natural astaxanthins, 85 parts of bathypelagic fish liver oils, 1 part of natural Vitamin E is by above-mentioned proportioning components, the bathypelagic fish liver oil is placed reactor, be heated to 50 ℃, natural astaxanthin is slowly joined in the reactor, add natural Vitamin E again, stirred 0.5 hour, and became miscella; B) miscella is cooled to 30 ℃, adopts microgranule and antibacterial in the membrane ultrafiltration device elimination miscella; C) filterable miscella enters automatic soft capsule granulator, makes natural astaxanthin and fishliver oil, and packing.
Embodiment 2:
A kind of preparation method of natural astaxanthin and fishliver oil, it is characterized in that adopting and be prepared as follows step: A) this capsular raw material and parts by weight are 5 parts of natural astaxanthins, 15 parts of bathypelagic fish liver oils, 0.1 part of natural Vitamin E is by above-mentioned proportioning components, the bathypelagic fish liver oil is placed reactor, be heated to 60 ℃, natural astaxanthin is slowly joined in the reactor, add natural Vitamin E again, stirred 0.5 hour, and became miscella; B) miscella is cooled to 30 ℃, adopts microgranule and antibacterial in the membrane ultrafiltration device elimination miscella; C) filterable miscella enters automatic soft capsule granulator, makes natural astaxanthin and fishliver oil, and packing.
Embodiment 3:
A kind of preparation method of natural astaxanthin and fishliver oil, it is characterized in that adopting and be prepared as follows step: A) this capsular raw material and parts by weight are 7 parts of natural astaxanthins, 45 parts of bathypelagic fish livers, 0.5 part of natural Vitamin E is by above-mentioned proportioning components, the bathypelagic fish liver is placed reactor, be heated to 55 ℃, natural astaxanthin oil is slowly joined in the reactor, add natural Vitamin E again, stirred 0.8 hour, and became miscella; B) miscella is cooled to 30 ℃, adopts microgranule and antibacterial in the membrane ultrafiltration device elimination miscella; C) filterable miscella enters automatic soft capsule granulator, makes natural astaxanthin and fishliver oil, and packing.
Claims (2)
1. the preparation method of a natural astaxanthin and fishliver oil is characterized in that the step for preparing is as follows:
A) this capsular raw material and parts by weight are 0.5～10 part of natural astaxanthin, 1～85 part of bathypelagic fish liver oil, 0.1～1 part of natural Vitamin E, by above-mentioned proportioning components, the bathypelagic fish liver oil is placed reactor, be heated to 50～60 ℃, slowly join natural astaxanthin in the reactor, add natural Vitamin E again, stirring became miscella in 0.5～1 hour;
B) miscella is cooled to 30 ℃, adopts microgranule and antibacterial in the membrane ultrafiltration device elimination miscella;
C) filterable miscella enters automatic soft capsule granulator, makes natural astaxanthin and fishliver oil, and packing.
2. the preparation method of natural astaxanthin and fishliver oil according to claim 1, it is characterized in that adopting and be prepared as follows step: A) this capsular raw material and parts by weight are 5 parts of natural astaxanthins, 15 parts of bathypelagic fish liver oils, 0.1 part of natural Vitamin E is by above-mentioned proportioning components, the bathypelagic fish liver oil is placed reactor, be heated to 60 ℃, natural astaxanthin is slowly joined in the reactor, add natural Vitamin E again, stirred 0.5 hour, and became miscella; B) miscella is cooled to 30 ℃, adopts microgranule and antibacterial in the membrane ultrafiltration device elimination miscella; C) filterable miscella enters automatic soft capsule granulator, makes natural astaxanthin and fishliver oil, and packing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2007100676616A CN100542545C (en) | 2007-03-28 | 2007-03-28 | A kind of preparation method of natural astaxanthin and fishliver oil |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2007100676616A CN100542545C (en) | 2007-03-28 | 2007-03-28 | A kind of preparation method of natural astaxanthin and fishliver oil |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101023963A CN101023963A (en) | 2007-08-29 |
| CN100542545C true CN100542545C (en) | 2009-09-23 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2007100676616A Expired - Fee Related CN100542545C (en) | 2007-03-28 | 2007-03-28 | A kind of preparation method of natural astaxanthin and fishliver oil |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104082741A (en) * | 2014-06-29 | 2014-10-08 | 宁波市成大机械研究所 | Soft seal oil capsule containing astaxanthin |
| CN104523754A (en) * | 2014-12-22 | 2015-04-22 | 威海百合生物技术股份有限公司 | Cod-liver oil drop pill for promoting infant development |
| EP3522903B1 (en) * | 2016-10-06 | 2021-11-03 | Beijing Gingko Group Biological Technology Co., Ltd. | Nutritional supplements affecting cardiovascular efficiency |
-
2007
- 2007-03-28 CN CNB2007100676616A patent/CN100542545C/en not_active Expired - Fee Related
Non-Patent Citations (4)
| Title |
|---|
| Effects of Astaxanthin Supplementationon Exercise-Induced Fatigue in Mice. Mayumi IKEUCHI et al.Biological Pharmaceutical bulletin,Vol.29 No.10. 2006 |
| Effects of Astaxanthin Supplementationon Exercise-Induced Fatigue in Mice. Mayumi IKEUCHI et al.Biological Pharmaceutical bulletin,Vol.29 No.10. 2006 * |
| 虾青素药理作用的研究进展. 林莉等.国外医学药学分册，第33卷第2期. 2006 |
| 虾青素药理作用的研究进展. 林莉等.国外医学药学分册，第33卷第2期. 2006 * |
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| CN101023963A (en) | 2007-08-29 |
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Granted publication date: 20090923 Termination date: 20100328 |