CN100501320C - 光学对准检测系统 - Google Patents

光学对准检测系统 Download PDF

Info

Publication number
CN100501320C
CN100501320C CNB2006101516982A CN200610151698A CN100501320C CN 100501320 C CN100501320 C CN 100501320C CN B2006101516982 A CNB2006101516982 A CN B2006101516982A CN 200610151698 A CN200610151698 A CN 200610151698A CN 100501320 C CN100501320 C CN 100501320C
Authority
CN
China
Prior art keywords
light
light source
array
light sources
fluid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB2006101516982A
Other languages
English (en)
Chinese (zh)
Other versions
CN1920479A (zh
Inventor
B·S·弗里茨
P·罗伊蒂曼
A·帕德马纳布汉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Honeywell International Inc
Original Assignee
Honeywell International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Honeywell International Inc filed Critical Honeywell International Inc
Publication of CN1920479A publication Critical patent/CN1920479A/zh
Application granted granted Critical
Publication of CN100501320C publication Critical patent/CN100501320C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B11/00—Measuring arrangements characterised by the use of optical techniques
    • G01B11/26—Measuring arrangements characterised by the use of optical techniques for measuring angles or tapers; for testing the alignment of axes
    • G01B11/27—Measuring arrangements characterised by the use of optical techniques for measuring angles or tapers; for testing the alignment of axes for testing the alignment of axes
    • G01B11/272—Measuring arrangements characterised by the use of optical techniques for measuring angles or tapers; for testing the alignment of axes for testing the alignment of axes using photoelectric detection means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/011—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells with lysing, e.g. of erythrocytes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/012—Red blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/016—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G01N2015/0238—Single particle scatter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1027—Determining speed or velocity of a particle
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
    • G01N35/085—Flow Injection Analysis

Landscapes

  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Length Measuring Devices By Optical Means (AREA)
CNB2006101516982A 2002-08-21 2003-08-15 光学对准检测系统 Expired - Fee Related CN100501320C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/225325 2002-08-21
US10/225,325 US6970245B2 (en) 2000-08-02 2002-08-21 Optical alignment detection system

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNB038244306A Division CN100422686C (zh) 2002-08-21 2003-08-15 光学对准检测系统

Publications (2)

Publication Number Publication Date
CN1920479A CN1920479A (zh) 2007-02-28
CN100501320C true CN100501320C (zh) 2009-06-17

Family

ID=31946298

Family Applications (2)

Application Number Title Priority Date Filing Date
CNB2006101516982A Expired - Fee Related CN100501320C (zh) 2002-08-21 2003-08-15 光学对准检测系统
CNB038244306A Expired - Fee Related CN100422686C (zh) 2002-08-21 2003-08-15 光学对准检测系统

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNB038244306A Expired - Fee Related CN100422686C (zh) 2002-08-21 2003-08-15 光学对准检测系统

Country Status (6)

Country Link
US (2) US6970245B2 (enExample)
EP (1) EP1546651A1 (enExample)
JP (2) JP2005536744A (enExample)
CN (2) CN100501320C (enExample)
AU (1) AU2003259851A1 (enExample)
WO (1) WO2004018967A1 (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7630063B2 (en) 2000-08-02 2009-12-08 Honeywell International Inc. Miniaturized cytometer for detecting multiple species in a sample
US8071051B2 (en) 2004-05-14 2011-12-06 Honeywell International Inc. Portable sample analyzer cartridge
US7283223B2 (en) * 2002-08-21 2007-10-16 Honeywell International Inc. Cytometer having telecentric optics
US7641856B2 (en) 2004-05-14 2010-01-05 Honeywell International Inc. Portable sample analyzer with removable cartridge
US8518328B2 (en) * 2005-12-27 2013-08-27 Honeywell International Inc. Fluid sensing and control in a fluidic analyzer
US8329118B2 (en) * 2004-09-02 2012-12-11 Honeywell International Inc. Method and apparatus for determining one or more operating parameters for a microfluidic circuit
US7420659B1 (en) * 2000-06-02 2008-09-02 Honeywell Interantional Inc. Flow control system of a cartridge
US7016022B2 (en) * 2000-08-02 2006-03-21 Honeywell International Inc. Dual use detectors for flow cytometry
US6970245B2 (en) * 2000-08-02 2005-11-29 Honeywell International Inc. Optical alignment detection system
US7061595B2 (en) * 2000-08-02 2006-06-13 Honeywell International Inc. Miniaturized flow controller with closed loop regulation
CN102519919B (zh) * 2004-04-23 2016-03-16 古河电气工业株式会社 试样的分离、识别、分注方法和其装置及解析装置
US8097225B2 (en) * 2004-07-28 2012-01-17 Honeywell International Inc. Microfluidic cartridge with reservoirs for increased shelf life of installed reagents
US7629173B2 (en) * 2004-12-29 2009-12-08 Corning Incorporated Optical reader system and method for monitoring and correcting lateral and angular misalignments of label independent biosensors
US7110192B2 (en) * 2005-01-12 2006-09-19 Dako Denmark A/S System and method for a composite lens for a flow cytometer
CN101663576B (zh) * 2005-04-12 2012-05-23 卡钳生命科学股份有限公司 用于微流体器件的紧凑型光检测系统
US8361410B2 (en) 2005-07-01 2013-01-29 Honeywell International Inc. Flow metered analyzer
EP1901846B1 (en) 2005-07-01 2015-01-14 Honeywell International Inc. A microfluidic card for rbc analysis
US8273294B2 (en) 2005-07-01 2012-09-25 Honeywell International Inc. Molded cartridge with 3-D hydrodynamic focusing
WO2007075920A2 (en) * 2005-12-22 2007-07-05 Honeywell International Inc. Hematological analyzer system with removable cartridge
US7485153B2 (en) * 2005-12-27 2009-02-03 Honeywell International Inc. Fluid free interface for a fluidic analyzer
US8182767B2 (en) * 2005-12-27 2012-05-22 Honeywell International Inc. Needle-septum interface for a fluidic analyzer
EP2963498B8 (en) * 2006-01-19 2017-07-26 Nikon Corporation Exposure apparatus, exposure method, and device manufacturing method
US7551278B2 (en) * 2006-05-12 2009-06-23 Honeywell International Inc. Fluid light guide system
US7380721B2 (en) * 2006-08-22 2008-06-03 Honeywell International Inc. Low-cost compact bar code sensor
EP2993688B1 (en) * 2006-08-31 2017-04-05 Nikon Corporation Exposure method and apparatus, and device manufacturing method
EP2993524B1 (en) * 2006-09-01 2017-10-25 Nikon Corporation Exposure method and apparatus and device manufacturing method
JP2009083382A (ja) * 2007-10-01 2009-04-23 Brother Ind Ltd 画像形成装置および画像処理プログラム
US8304245B2 (en) * 2007-11-02 2012-11-06 Children's Hospital And Research Center At Oakland Microfluidic flow lysometer device, system and method
US8037354B2 (en) 2008-09-18 2011-10-11 Honeywell International Inc. Apparatus and method for operating a computing platform without a battery pack
HU227875B1 (en) 2008-10-13 2012-05-29 Diatron Medicinai Instr Laboratoriumi Diagnosztikai Fejlesztoe Gyarto Zartkoerueen Muekoedoe Reszven Optical circulation cytometer furthermore testing method
US9034277B2 (en) 2008-10-24 2015-05-19 Honeywell International Inc. Surface preparation for a microfluidic channel
US20110133726A1 (en) * 2009-12-09 2011-06-09 Alexander Ballantyne Precision alignment system
WO2014152039A2 (en) 2013-03-14 2014-09-25 Cytonome/St, Llc Operatorless particle processing systems and methods
US9218069B2 (en) * 2013-04-11 2015-12-22 Avago Technologies General Ip (Singapore) Pte. Ltd. Optical sensing device to sense displacement
JP2014215041A (ja) * 2013-04-22 2014-11-17 株式会社堀場製作所 粒子計数装置およびその製造方法
KR102205900B1 (ko) * 2014-01-29 2021-01-21 삼성전자주식회사 분석장치 및 분석장치의 카트리지 장착상태를 판단하는 방법
EP3001177A1 (de) * 2014-09-29 2016-03-30 Grundfos Holding A/S Vorrichtung zum Erfassen von Partikeln in einer Flüssigkeit
CN107003227B (zh) * 2014-12-12 2020-06-05 贝克顿·迪金森公司 用于将光源与流动流对准的方法及其系统
EP3516369B1 (en) * 2016-09-22 2022-11-02 IMEC vzw Particle detection using thin lenses
KR102458722B1 (ko) * 2018-02-08 2022-10-26 프리시젼바이오 주식회사 유체 분석 장치 및 유체 분석 장치의 제어 방법
US10908065B2 (en) 2018-09-17 2021-02-02 Inguran, Llc Light collection from objects within a fluid column
CN113316715B (zh) * 2019-01-31 2024-03-15 快速定量微生物学股份有限公司 一种布置光学装置的盒、组件以及方法
WO2021211259A1 (en) * 2020-04-16 2021-10-21 Becton, Dickinson And Company Systems for light detection array multiplexing and methods for same
KR102599746B1 (ko) * 2021-11-08 2023-11-08 엘아이지넥스원 주식회사 레이저 스팟 계측용 근적외선 카메라 및 레이저 스팟 관측 방법

Family Cites Families (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3822095A (en) 1972-08-14 1974-07-02 Block Engineering System for differentiating particles
JPS5610566B2 (enExample) * 1974-06-08 1981-03-09
US3928094A (en) * 1975-01-16 1975-12-23 Fairchild Camera Instr Co Method of aligning a wafer beneath a mask and system therefor and wafer having a unique alignment pattern
US4267443A (en) * 1978-04-24 1981-05-12 Carroll Manufacturing Corporation Photoelectric input apparatus
US4275965A (en) * 1979-08-21 1981-06-30 United Technologies Corporation Long stroke, high resolution optical position sensor
JPS58143206A (ja) * 1982-02-19 1983-08-25 Canon Inc 位置検知信号処理装置
JPS59176606A (ja) * 1983-03-26 1984-10-06 Fujitsu Ltd 平板物体縁部検出装置
JPS59604A (ja) * 1982-06-02 1984-01-05 Fujitsu Ltd 対向照明形縁部検出装置
US4478077A (en) 1982-09-30 1984-10-23 Honeywell Inc. Flow sensor
US4501144A (en) 1982-09-30 1985-02-26 Honeywell Inc. Flow sensor
US4651564A (en) 1982-09-30 1987-03-24 Honeywell Inc. Semiconductor device
US4683159A (en) 1982-09-30 1987-07-28 Honeywell Inc. Semiconductor device structure and processing
US4478076A (en) 1982-09-30 1984-10-23 Honeywell Inc. Flow sensor
US4695034A (en) 1984-11-27 1987-09-22 Stec Inc. Fluid control device
US4704033A (en) 1986-03-06 1987-11-03 Micronix Corporation Multiple wavelength linear zone plate alignment apparatus and method
DE3640616A1 (de) 1986-11-27 1988-06-09 Standard Elektrik Lorenz Ag Justiervorrichtung
US4818263A (en) 1987-06-11 1989-04-04 Tektronix, Inc. Method and apparatus for precisely positioning microlenses on optical fibers
US4911616A (en) 1988-01-19 1990-03-27 Laumann Jr Carl W Micro miniature implantable pump
US4932989A (en) 1989-04-05 1990-06-12 At&T Bell Laboratories Method and apparatus for fabricating microlenses on optical fibers
CH679555A5 (enExample) 1989-04-11 1992-03-13 Westonbridge Int Ltd
ATE110142T1 (de) 1989-06-14 1994-09-15 Westonbridge Int Ltd Mikropumpe.
DE3926066A1 (de) 1989-08-07 1991-02-14 Ibm Deutschland Mikromechanische kompressorkaskade und verfahren zur druckerhoehung bei extrem niedrigem arbeitsdruck
CH681168A5 (en) 1989-11-10 1993-01-29 Westonbridge Int Ltd Micro-pump for medicinal dosing
US5171132A (en) 1989-12-27 1992-12-15 Seiko Epson Corporation Two-valve thin plate micropump
US5244537A (en) 1989-12-27 1993-09-14 Honeywell, Inc. Fabrication of an electronic microvalve apparatus
US5082242A (en) 1989-12-27 1992-01-21 Ulrich Bonne Electronic microvalve apparatus and fabrication
US5050429A (en) 1990-02-22 1991-09-24 Yamatake-Honeywell Co., Ltd. Microbridge flow sensor
US5096388A (en) 1990-03-22 1992-03-17 The Charles Stark Draper Laboratory, Inc. Microfabricated pump
US5975674A (en) * 1990-04-04 1999-11-02 Hewlett-Packard Company Optical path optimization for light transmission and reflection in a carriage-mounted inkjet printer sensor
DE69104585T2 (de) 1990-10-30 1995-05-18 Hewlett Packard Co Mikropumpe.
US5108623A (en) 1990-11-19 1992-04-28 Gould Inc. Moving web filter assembly
US5194909A (en) 1990-12-04 1993-03-16 Tycko Daniel H Apparatus and method for measuring volume and hemoglobin concentration of red blood cells
DE4119955C2 (de) 1991-06-18 2000-05-31 Danfoss As Miniatur-Betätigungselement
US5176358A (en) 1991-08-08 1993-01-05 Honeywell Inc. Microstructure gas valve control
US5225691A (en) * 1992-05-18 1993-07-06 Avalon Engineering, Inc. Semiconductor wafer cassette mapper with emitter and detector arrays for slot interrogation
EP0648351B1 (en) 1992-07-02 1997-10-08 Indigo N.V. Concentration detector for colored toner
US5441597A (en) 1992-12-01 1995-08-15 Honeywell Inc. Microstructure gas valve control forming method
WO1994027146A1 (en) 1993-05-14 1994-11-24 Coulter Corporation Reticulocyte analyzing method and apparatus utilizing light scatter techniques
JPH07270122A (ja) * 1994-03-30 1995-10-20 Canon Inc 変位検出装置、該変位検出装置を備えた露光装置およびデバイスの製造方法
GB9406551D0 (en) 1994-03-31 1994-05-25 Hjelm Nils M Chromatography system and methodology
US5793485A (en) 1995-03-20 1998-08-11 Sandia Corporation Resonant-cavity apparatus for cytometry or particle analysis
AU6541596A (en) 1995-06-16 1997-01-15 University Of Washington Microfabricated differential extraction device and method
US5922210A (en) 1995-06-16 1999-07-13 University Of Washington Tangential flow planar microfabricated fluid filter and method of using thereof
US5716852A (en) 1996-03-29 1998-02-10 University Of Washington Microfabricated diffusion-based chemical sensor
US5717631A (en) 1995-07-21 1998-02-10 Carnegie Mellon University Microelectromechanical structure and process of making same
US5726751A (en) 1995-09-27 1998-03-10 University Of Washington Silicon microchannel optical flow cytometer
IT1280475B1 (it) 1995-11-09 1998-01-20 Fiat Ricerche Dispositivi a microfiltri selettivi di colori e immagini.
DE19546570C1 (de) 1995-12-13 1997-03-27 Inst Mikro Und Informationstec Fluidpumpe
JP3308441B2 (ja) 1995-12-19 2002-07-29 シスメックス株式会社 尿中有形成分分析装置
US5863502A (en) 1996-01-24 1999-01-26 Sarnoff Corporation Parallel reaction cassette and associated devices
US5948684A (en) 1997-03-31 1999-09-07 University Of Washington Simultaneous analyte determination and reference balancing in reference T-sensor devices
US5971158A (en) 1996-06-14 1999-10-26 University Of Washington Absorption-enhanced differential extraction device
US5764674A (en) 1996-06-28 1998-06-09 Honeywell Inc. Current confinement for a vertical cavity surface emitting laser
US5799030A (en) 1996-07-26 1998-08-25 Honeywell Inc. Semiconductor device with a laser and a photodetector in a common container
AU717626B2 (en) 1996-10-03 2000-03-30 Debiotech S.A. Micro-machined device for fluids and method of manufacture
US6124663A (en) 1996-12-16 2000-09-26 The Boeing Company Fiber optic connector having a microelectromechanical positioning apparatus and an associated fabrication method
US5683159A (en) 1997-01-03 1997-11-04 Johnson; Greg P. Hardware mounting rail
US6097859A (en) 1998-02-12 2000-08-01 The Regents Of The University Of California Multi-wavelength cross-connect optical switch
US5974867A (en) 1997-06-13 1999-11-02 University Of Washington Method for determining concentration of a laminar sample stream
US6082185A (en) 1997-07-25 2000-07-04 Research International, Inc. Disposable fluidic circuit cards
US6346988B1 (en) * 1997-08-01 2002-02-12 Hama Sensors, Inc. Laser position array optical measuring system and method
US6007775A (en) 1997-09-26 1999-12-28 University Of Washington Multiple analyte diffusion based chemical sensor
US5822170A (en) 1997-10-09 1998-10-13 Honeywell Inc. Hydrophobic coating for reducing humidity effect in electrostatic actuators
US6106245A (en) 1997-10-09 2000-08-22 Honeywell Low cost, high pumping rate electrostatically actuated mesopump
US5901939A (en) 1997-10-09 1999-05-11 Honeywell Inc. Buckled actuator with enhanced restoring force
US5836750A (en) 1997-10-09 1998-11-17 Honeywell Inc. Electrostatically actuated mesopump having a plurality of elementary cells
US6054335A (en) 1997-12-12 2000-04-25 Xerox Corporation Fabrication of scanning III-V compound light emitters integrated with Si-based actuators
US6116756A (en) 1997-12-12 2000-09-12 Xerox Corporation Monolithic scanning light emitting devices
CA2320296A1 (en) 1998-05-18 1999-11-25 University Of Washington Liquid analysis cartridge
JP3522535B2 (ja) 1998-05-29 2004-04-26 忠弘 大見 圧力式流量制御装置を備えたガス供給設備
US6091197A (en) 1998-06-12 2000-07-18 Xerox Corporation Full color tunable resonant cavity organic light emitting diode
JP4001436B2 (ja) 1998-07-23 2007-10-31 三菱電機株式会社 光スイッチ及び光スイッチを用いた光路切換装置
US6032689A (en) 1998-10-30 2000-03-07 Industrial Technology Research Institute Integrated flow controller module
US6091537A (en) 1998-12-11 2000-07-18 Xerox Corporation Electro-actuated microlens assemblies
US6184607B1 (en) 1998-12-29 2001-02-06 Honeywell International Inc. Driving strategy for non-parallel arrays of electrostatic actuators sharing a common electrode
US6215221B1 (en) 1998-12-29 2001-04-10 Honeywell International Inc. Electrostatic/pneumatic actuators for active surfaces
US6097485A (en) 1999-03-08 2000-08-01 Integrated Waveguides, Inc. Microchip optical transport technology for use in a personal flow cytometer
WO2001009598A1 (en) 1999-07-28 2001-02-08 University Of Washington Fluidic interconnect, interconnect manifold and microfluidic devices for internal delivery of gases and application of vacuum
US6179586B1 (en) 1999-09-15 2001-01-30 Honeywell International Inc. Dual diaphragm, single chamber mesopump
US6281975B1 (en) 2000-03-07 2001-08-28 Eldex Laboratories, Inc. Capillary flow cell with bulbous ends
US20010030743A1 (en) 2000-03-10 2001-10-18 Carlos Araujo Laser alignment system with plural lasers for impingement on a single target
DE20008228U1 (de) * 2000-05-09 2002-01-03 Prüftechnik Dieter Busch AG, 85737 Ismaning Vorrichtung zur quantitativen Beurteilung der fluchtenden Lage zweier Maschinenteile, Werkstücke o.dgl.
US6970245B2 (en) * 2000-08-02 2005-11-29 Honeywell International Inc. Optical alignment detection system
US6549275B1 (en) 2000-08-02 2003-04-15 Honeywell International Inc. Optical detection system for flow cytometry

Also Published As

Publication number Publication date
CN1920479A (zh) 2007-02-28
JP2005536744A (ja) 2005-12-02
AU2003259851A1 (en) 2004-03-11
JP2010164573A (ja) 2010-07-29
WO2004018967A1 (en) 2004-03-04
EP1546651A1 (en) 2005-06-29
US20060256336A1 (en) 2006-11-16
US20030058445A1 (en) 2003-03-27
US7312870B2 (en) 2007-12-25
CN1688865A (zh) 2005-10-26
CN100422686C (zh) 2008-10-01
US6970245B2 (en) 2005-11-29

Similar Documents

Publication Publication Date Title
CN100422686C (zh) 光学对准检测系统
CN101065655B (zh) 用于流式细胞术的两用检测器
US7215425B2 (en) Optical alignment for flow cytometry
US7262838B2 (en) Optical detection system for flow cytometry
US7671987B2 (en) Optical detection system for flow cytometry
US6549275B1 (en) Optical detection system for flow cytometry
US6700130B2 (en) Optical detection system for flow cytometry
US6382228B1 (en) Fluid driving system for flow cytometry
US6597438B1 (en) Portable flow cytometry
CN101208593B (zh) 卡片的流动控制系统
EP2829941B1 (en) Miniaturized flow controller using closed loop regulation
US7471394B2 (en) Optical detection system with polarizing beamsplitter
US20030142291A1 (en) Portable scattering and fluorescence cytometer
EP3516369B1 (en) Particle detection using thin lenses

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20090617

Termination date: 20210815

CF01 Termination of patent right due to non-payment of annual fee