CN100497628C - 分离的编码t细胞诱导因子或白介素-21的核酸分子,其编码的蛋白和其应用 - Google Patents

分离的编码t细胞诱导因子或白介素-21的核酸分子,其编码的蛋白和其应用 Download PDF

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CN100497628C
CN100497628C CNB2005101169978A CN200510116997A CN100497628C CN 100497628 C CN100497628 C CN 100497628C CN B2005101169978 A CNB2005101169978 A CN B2005101169978A CN 200510116997 A CN200510116997 A CN 200510116997A CN 100497628 C CN100497628 C CN 100497628C
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tif
seq
cells
dna
molecules
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CN1796558A (zh
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劳尔·杜穆蒂尔
琼-克里斯托弗·雷诺尔德
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Wyeth LLC
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869Interleukin
    • AHUMAN NECESSITIES
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    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047Cells of the immune system
    • G01N33/505Cells of the immune system involving T-cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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CNB2005101169978A 2000-07-27 2001-06-27 分离的编码t细胞诱导因子或白介素-21的核酸分子,其编码的蛋白和其应用 Expired - Fee Related CN100497628C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62661700A 2000-07-27 2000-07-27
US09/626,617 2000-07-27

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CNB018131255A Division CN100448994C (zh) 2000-07-27 2001-06-27 分离的编码t细胞诱导因子或白介素-21的核酸分子,其编码的蛋白和其应用

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CN1796558A CN1796558A (zh) 2006-07-05
CN100497628C true CN100497628C (zh) 2009-06-10

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CNB2005101169978A Expired - Fee Related CN100497628C (zh) 2000-07-27 2001-06-27 分离的编码t细胞诱导因子或白介素-21的核酸分子,其编码的蛋白和其应用
CNB018131255A Expired - Fee Related CN100448994C (zh) 2000-07-27 2001-06-27 分离的编码t细胞诱导因子或白介素-21的核酸分子,其编码的蛋白和其应用
CNA2008101764854A Pending CN101423551A (zh) 2000-07-27 2001-06-27 分离的编码t细胞诱导因子或白介素-21的核酸分子,其编码的蛋白和其应用

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CNA2008101764854A Pending CN101423551A (zh) 2000-07-27 2001-06-27 分离的编码t细胞诱导因子或白介素-21的核酸分子,其编码的蛋白和其应用

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EP (2) EP1806404B1 (enExample)
JP (1) JP4113773B2 (enExample)
CN (3) CN100497628C (enExample)
AT (2) ATE478148T1 (enExample)
AU (1) AU7303301A (enExample)
CA (1) CA2416820A1 (enExample)
DE (2) DE60142861D1 (enExample)
ES (1) ES2349312T3 (enExample)
WO (1) WO2002010393A2 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7307161B1 (en) 1999-04-28 2007-12-11 Genetics Institute, Llc Human Gil-19/AE289 polynucleotides
US6939545B2 (en) 1999-04-28 2005-09-06 Genetics Institute, Llc Composition and method for treating inflammatory disorders
US20030170823A1 (en) 1999-12-23 2003-09-11 Presnell Scott R. Novel cytokine ZCYTO18
US20030012788A1 (en) 2000-07-27 2003-01-16 Jean-Christophe Renauld Method for influencing kinase pathways with IL-22
US20030023033A1 (en) * 2001-07-26 2003-01-30 Laure Dumoutier Novel class II cytokine receptors and uses thereof
ES2277947T3 (es) * 2000-10-13 2007-08-01 Eli Lilly And Company Procedimientos de uso de un polipeptido afin a il-17 humana para tratar enfermedades.
US7638604B2 (en) 2001-02-23 2009-12-29 Genetics Institute, Llc Monoclonal antibodies against interleukin-22
WO2003083062A2 (en) 2002-03-22 2003-10-09 Zymogenetics, Inc. Anti-il-tif antibodies and methods of using in inflammation
AU2003251633A1 (en) 2002-07-01 2004-01-19 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Il-21 as a regulator of immunoglobin production
CA2497661A1 (en) * 2002-09-11 2004-03-25 Genentech, Inc. Compositions and methods for the diagnosis of immune related diseases using pro71061
US20060177421A1 (en) * 2002-10-11 2006-08-10 Novo Nordisk A/S Treatment of allergic conditions by use of il 21
EP1553970A1 (en) * 2002-10-11 2005-07-20 Novo Nordisk A/S Treatment of allergic conditions by use of il 21
ATE490275T1 (de) * 2003-06-23 2010-12-15 Genetics Inst Llc Antikörper gegen interleukin-22 und verwendungen dafür
EP3006466B1 (en) 2005-12-02 2018-08-01 Genentech, Inc. Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling involving antibodies that bind to il-22 and il-22r
TWI417301B (zh) 2006-02-21 2013-12-01 Wyeth Corp 對抗人類介白素-22(il-22)之抗體及其用途
TW200744634A (en) 2006-02-21 2007-12-16 Wyeth Corp Methods of using antibodies against human IL-22
IT1404858B1 (it) 2011-02-21 2013-12-09 Milano Politecnico Supporto anti-sismico.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843697A (en) 1996-07-17 1998-12-01 University Of Medicine And Dentistry Of New Jersey Cells expressing IL-10 receptor and the CRFB4 gene product, an IL-10 receptor accessory protein
DE19848683B4 (de) 1998-10-22 2004-05-06 Basf Ag Verbundschichtplatte
JP3769189B2 (ja) * 1998-10-26 2006-04-19 ルードヴィッヒ インスティテュート フォー キャンサー リサーチ T細胞誘導性因子(tif)をコードする単離された核酸分子、コードされたタンパク質およびその使用
EP1177312B1 (en) * 1999-04-28 2007-10-31 Genetics Institute, LLC Human gil-19/ae289 proteins and polynucleotides encoding same
WO2000073457A1 (en) * 1999-05-27 2000-12-07 Schering-Corporation Mammalian interleukin-10 homologs: il-d110 and il-d210
CA2393369A1 (en) * 1999-12-03 2001-06-07 Zymogenetics, Inc. Human cytokine receptor

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Cloning and Characterization of IL-10-Related TCell-DerivedInducible Factor (IL-TIF), a Novel CytokineStructurallyRelated to IL-10 and Inducible by IL-9. Laure Dumoutier等.J. of Immunology,Vol.164 . 2000
Cloning and Characterization of IL-10-Related TCell-DerivedInducible Factor (IL-TIF), a Novel CytokineStructurallyRelated to IL-10 and Inducible by IL-9. Laure Dumoutier等.J. of Immunology,Vol.164 . 2000 *

Also Published As

Publication number Publication date
JP2004504842A (ja) 2004-02-19
WO2002010393A2 (en) 2002-02-07
CA2416820A1 (en) 2002-02-07
WO2002010393A3 (en) 2003-01-30
CN100448994C (zh) 2009-01-07
EP1305419B1 (en) 2007-06-27
CN101423551A (zh) 2009-05-06
JP4113773B2 (ja) 2008-07-09
EP1305419A2 (en) 2003-05-02
CN1443241A (zh) 2003-09-17
ATE365801T1 (de) 2007-07-15
ATE478148T1 (de) 2010-09-15
CN1796558A (zh) 2006-07-05
EP1806404A1 (en) 2007-07-11
AU7303301A (en) 2002-02-13
ES2349312T3 (es) 2010-12-29
DE60142861D1 (de) 2010-09-30
DE60129137D1 (de) 2007-08-09
EP1806404B1 (en) 2010-08-18

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