CN100482674C - 皮肤瘢痕形成的减少 - Google Patents

皮肤瘢痕形成的减少 Download PDF

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Publication number
CN100482674C
CN100482674C CNB2004800406132A CN200480040613A CN100482674C CN 100482674 C CN100482674 C CN 100482674C CN B2004800406132 A CNB2004800406132 A CN B2004800406132A CN 200480040613 A CN200480040613 A CN 200480040613A CN 100482674 C CN100482674 C CN 100482674C
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China
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rad
cip1
waf1
wound
purposes
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Expired - Fee Related
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CNB2004800406132A
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English (en)
Chinese (zh)
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CN1906205A (zh
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D·古
M·泽佩达
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Canji Inc
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Canji Inc
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4703Inhibitors; Suppressors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CNB2004800406132A 2003-11-24 2004-11-23 皮肤瘢痕形成的减少 Expired - Fee Related CN100482674C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52499303P 2003-11-24 2003-11-24
US60/524,993 2003-11-24

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN2009101287188A Division CN101507822B (zh) 2003-11-24 2004-11-23 皮肤瘢痕形成的减少

Publications (2)

Publication Number Publication Date
CN1906205A CN1906205A (zh) 2007-01-31
CN100482674C true CN100482674C (zh) 2009-04-29

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Family Applications (2)

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CNB2004800406132A Expired - Fee Related CN100482674C (zh) 2003-11-24 2004-11-23 皮肤瘢痕形成的减少
CN2009101287188A Expired - Fee Related CN101507822B (zh) 2003-11-24 2004-11-23 皮肤瘢痕形成的减少

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CN2009101287188A Expired - Fee Related CN101507822B (zh) 2003-11-24 2004-11-23 皮肤瘢痕形成的减少

Country Status (13)

Country Link
US (3) US7465442B2 (https=)
EP (1) EP1692154A4 (https=)
JP (2) JP4842139B2 (https=)
KR (1) KR101167330B1 (https=)
CN (2) CN100482674C (https=)
AU (1) AU2004293474B2 (https=)
BR (1) BRPI0416920A (https=)
CA (1) CA2546287C (https=)
IL (1) IL175603A (https=)
NO (1) NO20062978L (https=)
NZ (1) NZ546983A (https=)
WO (1) WO2005051971A1 (https=)
ZA (1) ZA200604147B (https=)

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EP1692154A4 (en) * 2003-11-24 2009-07-08 Canji Inc REDUCTION OF SKIN TEMPERING
EP2249718B1 (en) 2008-01-14 2019-09-18 Conventus Orthopaedics, Inc. Apparatus for fracture repair
CA2746527A1 (en) 2008-09-22 2010-03-25 Rxi Pharmaceuticals Corporation Rna interference in skin indications
WO2011088172A1 (en) 2010-01-15 2011-07-21 Brenzel Michael P Rotary-rigid orthopaedic rod
CN102821707B (zh) 2010-01-20 2016-02-03 康文图斯整形外科公司 用于骨接近和骨腔准备的装置及方法
CN108125714A (zh) 2010-03-08 2018-06-08 康文图斯整形外科公司 用于固定骨植入物的装置及方法
BR112012024049A2 (pt) 2010-03-24 2017-03-01 Rxi Pharmaceuticals Corp interferência de rna em indicações dérmicas e fibróticas
EP3077050B1 (en) * 2013-12-04 2020-10-21 Phio Pharmaceuticals Corp. Methods for treatment of wound healing utilizing chemically modified oligonucleotides
CA2969316A1 (en) 2013-12-12 2015-06-18 Conventus Orthopaedics, Inc. Tissue displacement tools and methods
KR102506169B1 (ko) 2014-09-05 2023-03-08 피오 파마슈티칼스 코프. Tyr 또는 mmp1을 표적화하는 핵산을 사용한 노화 및 피부 장애의 치료 방법
EP3442588A4 (en) 2016-04-14 2020-02-19 Trizell Ltd. STABILIZING VIRUS VECTORS
WO2018195355A1 (en) 2017-04-19 2018-10-25 Rxi Pharmaceuticals Corporation Topical delivery of nucleic acid compounds
WO2019010252A2 (en) 2017-07-04 2019-01-10 Conventus Orthopaedics, Inc. Apparatus and methods for treatment of a bone

Citations (1)

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US20020111304A1 (en) * 2000-12-01 2002-08-15 Andrius Kazlauskas Methods and compositions for treating fibrotic diseases

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NO20062978L (no) 2006-06-26
CA2546287C (en) 2014-04-22
JP2011207912A (ja) 2011-10-20
CN101507822B (zh) 2012-06-06
CA2546287A1 (en) 2005-06-09
BRPI0416920A (pt) 2007-01-23
IL175603A0 (en) 2006-09-05
KR20060127414A (ko) 2006-12-12
US20110129534A1 (en) 2011-06-02
IL175603A (en) 2011-02-28
US8329671B2 (en) 2012-12-11
NZ546983A (en) 2009-05-31
AU2004293474B2 (en) 2010-12-23
US20050271623A1 (en) 2005-12-08
AU2004293474A1 (en) 2005-06-09
KR101167330B1 (ko) 2012-07-23
CN1906205A (zh) 2007-01-31
EP1692154A1 (en) 2006-08-23
CN101507822A (zh) 2009-08-19
US7465442B2 (en) 2008-12-16
WO2005051971A1 (en) 2005-06-09
JP4842139B2 (ja) 2011-12-21
US20090142397A1 (en) 2009-06-04
EP1692154A4 (en) 2009-07-08
JP2007512377A (ja) 2007-05-17
ZA200604147B (en) 2007-11-28

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Granted publication date: 20090429

Termination date: 20161123