CN100477930C - Health-care drink - Google Patents
Health-care drink Download PDFInfo
- Publication number
- CN100477930C CN100477930C CNB2004800009570A CN200480000957A CN100477930C CN 100477930 C CN100477930 C CN 100477930C CN B2004800009570 A CNB2004800009570 A CN B2004800009570A CN 200480000957 A CN200480000957 A CN 200480000957A CN 100477930 C CN100477930 C CN 100477930C
- Authority
- CN
- China
- Prior art keywords
- water
- vitamin
- soluble core
- healthy beverage
- core albumen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention is to provide a nutritional drink that enhances the potency of human health retention and promotion as compared with those of conventional nutritional drinks. As means for solving problems there is provided a nutritional drink dose with water-soluble nucleoprotein, characterized in that it contains, per 720 ml of nutritional drink: water-soluble nucleoprotein 1500 mg to 40000 mg, collagen 30g to 140g, chondroitin 50 mg to 200 mg, hyaluronic acid 20 mg to 80 mg, zinc 10 mg to 100 mg, vitamin c 500 mg to 14000 mg, vitamin b1 2 mg to 40 mg, vitamin b2 3 mg to 50 mg, vitamin b6 3 mg to 50 mg, vitamin b12 0.3 g to 7.0 g, and other additive ingredients plus balance water, the water-soluble nucleoprotein being one obtained by reducing the molecular weight of nucleoprotein contained in soft roe of fish to thereby render the same water-soluble.
Description
Technical field
The present invention relates to healthy beverage, in more detail, relate to existing healthy beverage and comparing, effect is promoted in the maintenance of human beings'health more advance the healthy beverage that one deck has improved.
Background technology
In recent years, people for health care generally improve, the result has proposed to be called as the food of healthy beverage.As one of them, for example, the applicant has proposed to add the healthy beverage (patent documentation 1) of water-soluble core albumen.By picked-up disclosed healthy beverage in patent documentation 1, confirming for example has, and improves with health, can be good at sleep (sleep), asthma during slight moving disappears, appetite increases, and pachylosis disappears, and constipation is eliminated, the root blackening of white hair, acne (thing of emerging) disappear, and muscle power strengthens, and the WA sensation is salubrious, the state of stomach and intestine improves, nympholepsy, the disappearance of being still drank after a night, of pink and healthy-looking, it is the main effect that relates to the health aspect that skin polishes etc., and, for example becoming substantial with body and mind, it is vigorous that vigour becomes, it is easily bright and clear that mood becomes, it is leisurely and comfortable that mood becomes, and is not limited to oneself, also becomes when associating with others not repel the effect that relates to spiritual aspect that grade is the master.But, in this healthy beverage, still leave and more enter the leeway that one deck improves above-mentioned effect.In addition, zinc is known for the effect of human body, by picked-up zinc, can be kept the normal sense of taste with what is called, and is anti-loss, promotes to cure the wound, and keeps the effect (non-patent literature 1, non-patent literature 2) of fecundity.
Patent documentation 1: the spy opens the 2003-325149 communique
Non-patent literature 1: the nutritional labeling バ イ Block Le useful, middle village fourth time prison, (strain) housewife and life society's (the 96th page to 99 pages) to health
Non-patent literature 2: be used to improve the acquisition method of the vitamin and minerals of symptom, write thoroughly the Fukui, and ball is apt to (strain) (the 111st page to 114 pages)
Disclosure of an invention
The problem that invention will solve
The present inventor, the new type health beverage that has the effect higher than the effect of disclosed healthy beverage in above-mentioned patent documentation 1 with exploitation is a problem, furthers investigate.
In the exploitation of new type health beverage, the present inventor finds, when in existing healthy beverage, cooperating zinc, find the healthy beverage of this adding zinc, in whole assessment items of effect usefulness, given play to synergy above the effect behind the picked-up patent documentation 1 disclosed healthy beverage of anticipation, and, especially unexpectedly found, even the project of the effect usefulness except that the project that can think the effect usefulness that zinc proves effective also all obtains significantly high evaluation.Further the present inventor finds, zinc with as the water-soluble core albumen of the composition of existing healthy beverage and the match ratio of collagen, to above-mentioned synergy, to exert an influence as long preservation stability of drink agent etc., therefore, by with its match ratio optimization, and finished the present invention.
Solve the method for problem
Be that first kind of mode of the present invention relates to a kind of healthy beverage that adds water-soluble core albumen, it is characterized in that this healthy beverage of every 720ml contains
Water-soluble core protein 15 00mg～40000mg,
Collagen 30g～140g,
Chondroitin 50mg～200mg,
Hyaluronic acid 20mg～80mg,
Zinc 10mg～100mg,
Vitamin C 500mg～14000mg,
Vitamin B1 2mg～40mg,
Vitamin B2 3mg～50mg,
Vitamin B6 3mg～50mg,
The water of cobalamin 0.3 μ g～7.0 μ g and other adding ingredients and nubbin,
Above-mentioned water-soluble core albumen is by the nucleoprotein in the fish sperm being carried out the degraded water miscible water-soluble core albumen that becomes.
The second way of the present invention relates to the healthy beverage that has added water-soluble core albumen, it is characterized in that, this healthy beverage of every 720ml contains
Water-soluble core protein 25 00mg～35000mg,
Collagen 60g～100g,
Chondroitin 80mg～150mg,
Hyaluronic acid 30mg～60mg,
Zinc 20mg～50mg,
Vitamin C 600mg～10000mg,
Vitamin B1 10mg～30mg,
Vitamin B2 15mg～40mg,
Vitamin B6 15mg～40mg,
The water of cobalamin 1.5 μ g～5.0 μ g and other adding ingredients and nubbin,
Above-mentioned water-soluble core albumen is by the nucleoprotein in the fish sperm being carried out the degraded water miscible water-soluble core albumen that becomes.
Optimal way of the present invention relates to the healthy beverage that has added water-soluble core albumen, it is characterized in that, water-soluble core albumen is for by carrying out the nucleoprotein in the fish sperm of dog salmon, trout or catfish in the degraded water miscible water-soluble core albumen that becomes.
Other optimal ways of the present invention relate to the healthy beverage that has added water-soluble core albumen, it is characterized in that, water-soluble core albumen contain more than or equal to 20 quality % with nucleoprotein with nuclease and Protease Treatment obtain degraded after oligonucleotides/nucleosides and oligopeptides.
The invention still further relates to the healthy beverage that has added water-soluble core albumen in addition, it is characterized in that, as the active ingredient beyond the active ingredient of above-mentioned healthy beverage, further contain at least a in juice, honey, spices, anticorrisive agent and the colouring agent that is selected from vitamins, mineral matter class, amino acids, peptide class, carbohydrate, water-solubility vegetable fibres, fruit or vegetables.
The effect of invention
Healthy beverage of the present invention is to have cooperated the composition of zinc in the gradation composition of disclosed healthy beverage in patent documentation 1, and makes and contain 10mg～100mg zinc, 1500mg～40000mg water-soluble core albumen and 30g～140g collagen among every 720ml.By this healthy beverage of regular this composition of picked-up, compare with disclosed healthy beverage in patent documentation 1, make the effect that keeps or promote human health, for example, improve, can be good at sleep (sleep) with health, asthma during slight moving disappears, appetite increases, and pachylosis disappears, and constipation is eliminated, the root blackening of white hair, acne (thing of emerging) disappear, and muscle power strengthens, and the WA sensation is salubrious, the state of stomach and intestine improves, nympholepsy, the disappearance of being still drank after a night, of pink and healthy-looking, skin polishes, dysgeusia is improved, and hindering the healing etc. easily that becomes is the main effect that relates to the health aspect, and, for example become substantial with body and mind, it is pure that vigour becomes, and it is easily bright and clear that mood becomes, and it is leisurely and comfortable that mood becomes, be not limited to oneself, also become when associating with others and do not repel, it is the main effect that relates to spiritual aspect that the improvement of the excessive diet tendency of apocleisis waits, and further improves synergistically.Particularly also have the following advantages, for thinking to absorb the effect that zinc causes. for the project of the effect usefulness beyond the usefulness, for example can see, can be good at sleep (sleep), asthma during slight motion disappears, and constipation is eliminated, the salubrious remarkable effect of improving that waits of WA sensation.
The best mode that carries out an invention
Recently, confirmed that water-soluble core albumen has the oxidative damage that makes gene and lowers, repaired the effect of damage.The deterioration and the damage of the oxidation modificator gene of gene., thinking gradually to the reflection that the care of environmental assessment improves as the mankind, get rid of as far as possible or suppress to be subjected to oxidative damage to gene from living environment, is extremely important keeping and promoting aspect the human health.
Here just carry out schematic illustration for the harmfulness of the oxidative damage of gene, biological hereditary information, the nucleic acid such with DNA be in the gene of inscape by adenine, thymidine, guanine and 4 kinds of alkali yl codings of cytimidine, this has been a well known fact.But gene is owing to be exposed in ultraviolet ray irradiation, various chemical substance, particularly carcinogen and the active oxygen source, is subjected to oxidative damage and produces copy error under certain frequency.This copy error makes hereditary information produce deterioration, becomes various illness or aging reasons such as cell or individual generation cancer.Therefore, think by checking that certain material is the oxidative damage of promotion or suppressor, can judge that this material has harmfulness or has validity biology.
As the method for biologically evaluating of the material that is undertaken by the frequency of determining to cause gene damage, can be set forth in the international disclosed method in No. 0169235 communique that discloses.In the method, be conceived to constitute the oxidation of the monokaryon glycosides of gene, in containing the solution of analyte, add 2 '-deoxyguanosine (dG), through the regular hour and/or after applying the oxidation load of ultraviolet ray irradiation etc., be determined at the oxysome of the dG that exists in the above-mentioned solution: 8-hydroxyl-2 '-concentration of deoxyguanosine (8OHdG).Then, according to the growing amount of 8OHdG, determine the harmfulness of analyte or having or not and degree of validity.The growing amount of 8OHdG more more thinks that the harmfulness of analyte is high more, and on the other hand, the growing amount of 8OHdG is few more thinks that the validity of analyte is high more.
Based on the above-mentioned method of biologically evaluating of the growing amount of measuring 8OHdG, by nearest research, the maintenance of health is promoted in the effective existing healthy beverage being considered to, confirm to exist and much contain the material that gene is had the composition of oxidative damage.Therefore, if will reduce the oxidative damage of gene, and then repair the active ingredient of damaging and add in the healthy beverage, can give unexistent new effect in existing healthy beverage to healthy beverage so, expect very much the appearance of such healthy beverage.In addition, now, the variation of the kind of the active ingredient of healthy beverage or its cooperation ratio and the relation of its effect are also not necessarily clear and definite.Think and cooperate the variation of ratio along with the kind of active ingredient or its and change as the resultant effect of healthy beverage.But healthy beverage of the present invention is provided as and obtains optimum efficiency and cooperated each active ingredient, and the maintenance of human health promoted real effectively healthy beverage.
As the water-soluble core albumen of the active ingredient of healthy beverage of the present invention, can obtain by the nucleoprotein from the fish sperm.Below, water-soluble core albumen is described.Water-soluble core albumen can be made by the fish sperm (spermaries of fish).The fish sperm has only a few part at present as edible and be utilized, and the major part processing that goes out of use is the aquatic resources that are utilized not too effectively.But the fish sperm contains and a lot of are the nucleic acid of principal component with DNA and are the albumen of principal component with the nucleoprotamine, has confirmed that it significantly reduces the oxidative damage of gene, and has had the effect of the damage of repairing.
Nucleoprotein is by degraded in water-soluble core albumen.Above-mentioned by the material after degraded, be in water-soluble core albumen, to contain more than or equal to the oligonucleotides/nucleosides of 20 quality % and the material of oligopeptides.Degraded by in this wise the nucleic acid in the nucleus and albumen being carried out, can be under the condition that keeps original validity and in alimentary canal, digest and assimilate easily.Because it is water-soluble that the nucleoprotein after degraded becomes, so can easily cooperate in healthy beverage.In addition, so-called here water-soluble be meant can be in water with character more than or equal to the concentration dissolving of 0.1 quality %.
The water-soluble core albumen of Huo Deing has good gene oxidative damage inhibitory action and wound repair effect like this.The gene oxidative damage becomes the hereditary information generation deterioration that is encoded in gene, and various illness or aging reason such as carcinogenic, and water-soluble core albumen when gene being applied the oxidation load, has its oxidative damage of remarkable inhibition, and repair the effect of damage.
Below, the serviceability of water-soluble core albumen is illustrated in further detail.The nucleus of known fish contains a lot of nucleoprotamine, and this albumen is to be the protein of principal component with the arginine, and decomposes nucleoprotamine and the oligopeptides that obtains shows excellent effect such as anti-allergic effects, skin makeup effect.Nucleic acid have skin makeup, prevent and make the life better habit disease (adult diseases) or aging effect in addition.Therefore, be the degraded nucleoprotein (water-soluble core albumen) of raw material by making with the fish sperm, can obtain to have excellent gene oxidative damage and suppress repair, also have both goods simultaneously from the effect of nucleic acid and nucleoprotamine.Above-mentioned fish for example are meant, chum salmon, trout, catfish, cod etc., preferred especially chum salmon, trout or catfish.After from the fish sperm of these fishes, skin, muscle, blood vessel etc. being removed, refiningly remove oil content, carry out the enzyme resolution process with nuclease and protease, can make water-soluble core albumen.
The water-soluble core albumen that in this healthy beverage, uses, preferably contain more than or equal to 20 quality % with nucleoprotein with nuclease and Protease Treatment and obtain degraded after oligonucleotides/nucleosides and oligopeptides.
Below, each composition of this healthy beverage is described.
I) water-soluble core albumen
" nucleic acid " of playing an important role in biological phenomena is present in the nucleus in the cell of all biological, and this nucleic acid has two kinds of DNA and RNA.
(1) DNA (DNA)
If spend the growth stage then the DNA manufacturing capacity swashs and to subtract.DNA conveys hereditary information as the original shape of gene, and it is whole that the division growth energy of control cell produces, and the birth of domination cell is to withering away.DNA is pentose, phosphoric acid, also have 4 kinds of bases (A, G, C, the T) structure of helical form combination, utilize the DNA of (from the beginning synthetic) that in liver, be synthesized in vivo and the nucleic acid that from food, absorbs by two kinds of DNA of synthetic (remedying synthetic) again.But if spend the growth stage, the ability decay of then making in liver can produce fissional speed and descend or the bad cell of character, or incomplete cell.This becomes adult diseases or aging reason and shows various symptoms.Therefore, be necessary the DNA of the corresponding amount of amount that supply and manufacturing capacity reduce.
(2) effect of DNA
1) transmits the gene information all biological, in growth course, make a large amount of divisions of cell make health.If the health manufacturing is finished, then proceed of the operation of aging cell with new cell exchange.Normal DNA has and makes when carrying out cell division and self identical DNA or nuclear, and according to ordering the effect made from the old identical cell of cell.
2) synthetic DNA of protein or RNA make protein (health).Headed by heart, liver, skin, the principal component of health is a protein.Relevant with the various chemical reactions that take place in vivo in addition enzyme also is made of protein.These protein are instructions of the DNA that all imported according to hereditary information, RNA (ribonucleic acid) combination amino acid and manufacturedly go out.But, if this amino acid whose combination becomes even a difference is arranged, so just becoming incomplete protein, original function becomes inoperative, becomes to carry out normal chemical reaction.Its result, the hair of blood or skin, hair, the cell of internal organ go bad, and become the reason of aging phenomenon or adult diseases.
The main effect of＜DNA (nucleic acid) 〉
A. absorb the initial effect that nucleic acid begins and be shown as, the expression of face begins to change.This be because, skin begins to tighten and removes wrinkle or lax, spot then also becomes not obvious.In addition, the skin of the aging drying that causes also begins to become moistening.
The superfluous such metabolic disorder of fat secretion that b. will become the reason of acne etc. turns back to normal state.
C. the reason of alopecia or white hair is the fissional unusual of the decline of fissional speed of ball top portion and ball top portion, by promoting normal cell division, anti-loss or white hair.
D. make respiratory function promote the function that improves lung, prevent fatigue.
E. prevent the increase of cholesterol, be of value to arteriosclerotic prevention.
The CBF or the zmount of oxygen consumption of brain are increased, cerebral vascular resistance is reduced.Improvement to the sequelae of headstroke, encephalomalacia etc. is effective.
CF is increased, improve myocardial metabolism, so effective to the prevention of cardiac insufficiency, angina pectoris, cardiomyopathy.
The stomach CBF is increased, enliven the wriggling of stomach and intestine.The effect that promotes defaecation is also arranged in addition.
I. effective to the improvement of aging, the eye fatigue that prevents brain, dysacousis.
J. in addition, improve the cause of disease that the depths hides at all from the aspect of so-called cytoactiveization.
The picked-up of＜DNA (nucleic acid) 〉
The picked-up of DNA nucleic acid (nucleoprotein) may not felt such effect in the young man of growth stage.But, aging be prepared since 10 generations.Therefore, begin supply nucleic acid (nucleoprotein) since young, keep and promote normal cell division, can be described as and prevent the best way of wearing out.Being paid close attention to as the food that contains a large amount of nucleic acid (nucleoprotein), is the fish sperm and brewer's yeast.But these food generally not too are eaten.Even think the edible problem that also has taste and store method in addition.Just because of this, the form picked-up with dietary supplement necessitates.The water-soluble core albumen that uses in healthy beverage of the present invention is this nucleoprotein to be carried out enzyme handle and be processed into water-solublely, it can be added in the beverage and exploitation.Every this healthy beverage of 720ml preferably adds 1500mg～40000mg water-soluble core albumen, especially preferably adds 2500mg～35000mg.If be less than 1500mg, can not bring into play the effect of regulation so, if surpass 4000mg, the difficulty that then becomes is dissolved in water.The situation of healthy beverage of the present invention is that the use level that can make water-soluble core albumen also increases greatly than the use level in the disclosed healthy beverage in the patent documentation 1, thus, and improved effect usefulness more significantly.
II) collagen
Collagen, for contain maximum protein in animal body, the 20 quality % of all protein that occupy organism are to 40 quality %.Collagen exists as fibrous protein with the form of burying in the gap of the cell of health and cell, becomes the main composition composition of the connective tissue of skin, bone, cartilage, tendon etc. especially.All 40 quality % of collagen quantity are contained in the skin, and 20 quality % are contained in bone and the cartilage, in addition, are distributed widely in whole bodies such as blood vessel and internal organ.Like this, collagen is as the constituent material of the shape of body support and internal organs and work, in addition, and as making the standing ground (matrix) that mutually combines between the cell also bring into play the effect of solid.Collagen confirms that the propagation of pair cell or the organism activity of the formation of organ, the healing of promotion wound etc. also have a significant impact outside the function of these physics.On the other hand, what can make collagen is fibroblast, cartilage cell, Gegenbaur's cell etc., and these, become the relation that influences mutually.
＜collagen and aging between relation
In human body, the decomposition of collagen and synthetic always carried out repeatedly.If be getting in years, then balance disorder becomes many with the synthetic decomposition of comparing of collagen.This is a kind of of aging phenomenon, because collagen loses flexibility, so or wrinkle or lax takes place, or joint or bone pain.Therefore, aging in order to resist, be necessary the supply collagen, enhance metabolism.
＜collagen have a form
If collagen is observed on microcosmic ground, become 3 spiral helicine elongated molecular aggregates, the structure of coordinating.Collagen can not directly dissolve in water, and if long-time and water heats, then 3 chains are opened under certain temperature, become the structure that can be dissolved in water, can extract from solution.This is called gelatin.Though the form difference, same thing, fish jelly or stewed muscles, pig bone made soup etc. just are connected in the daily culinary art and can put into practice.Therefore, we can say the edible food that contains a lot of collagens, and identical meaning is arranged with any form picked-up gelatin.
＜as the meaning of the collagen of food 〉
In recent years, reaching healthy, cosmetic result by edible collagen becomes topic, and usually, and so-called " collagen " is meant " gelatin " or " collagen peptide " after degraded with gelatin in food products market.Relevant for the picked-up of collagen, to preventing effectively report such as hypertension or mitigating osteoporosis disease, healing arthritis.In addition, also, seek returning to the youth of skin, or improve the report of cosmetic result of the moisture retention etc. of skin relevant for collagen synthetic that promotes in vivo.Be the society that confronts the problem of aging population, can think that the importance of collagen is more urgent.Healthy beverage of the present invention, from the viewpoint of effect usefulness, more preferably the use level of collagen than disclosed healthy beverage in patent documentation 1 still less.Every 720ml healthy beverage of the present invention preferably adds 30g～140g collagen, especially preferably adds 60g～100g.If be less than 30g, then can not reach the effect of this healthy beverage regulation.If surpass 140g then uneconomical.
III) chondroitin
The food chondroitin also claims the chondroitin protein complexes, is that the protein of the mucopolysaccharide of the chondroitin sulfate that will contain in a large number in the connective tissue of animal or cartilage etc. or collagen etc. extracts with the form of nature, and is refined to the product of the degree that food uses.Also claim mucopolysaccharide in addition in a broad sense.If illustrate in greater detail, then this mucopolysaccharide has acidity and neutrality, and neutral mucopolysacchauide is suitable with the high viscosity materials matter or the blood type material that cover gastric mucosa.On the other hand, the major part of the high viscosity materials matter in the connective tissue of the eyeball of animal, cartilage, skin, tendon, vascular wall, ligament, umbilical cord etc. is an acid mucopolysaccharide.
Food is as follows with the physiological action of chondroitin.
Regulate the moisture of extracellular fluid.
The formationization bone
Cure wound
Protect from infection
Lubrication
Stop blood clotting
Purified lipase serum
Keep the transparency of eye
Every 720ml healthy beverage of the present invention preferably adds the soft element of 50mg～200mg, especially preferably adds 80mg～150mg.
IV) hyaluronic acid
＜hyaluronic function 〉
Hyaluronic acid is mucopolysaccharide a kind of of high viscosity, is contained in ligament, the joint of animal, vitreous humor of eyeball etc.Solution or the gel of making thickness in vivo with protein are arranged, connect the function of cell and cell.In addition, the intrusion of avoiding bacterium as the lubricant that prevents joint friction or for the protection health is worked.
＜hyaluronic feature 〉
Hyaluronic acid has very excellent moisture retention, has the so-called moisture holding capacity that keeps the brute force of about 6 premium on currency in 1g.In addition,, then form the diaphragm that obtains moist feeling, smooth feeling, so beyond food, for example prevent agent or, also cooperation in cosmetics etc. as the skin anti wrinkling agent as pachylosis if owing to be applied on the skin.Every 720ml healthy beverage of the present invention preferably adds 20mg～80mg hyaluronic acid, especially preferably adds 30mg～60mg.
V) zinc
Zinc constitutes more than or equal to 80 kinds of enzymes, and is the active necessary element more than or equal to 200 kinds of enzymes.Symptom when lacking zinc in the human body for example is as follows.
Skin symptom: dry skin is coarse, acne, alopecia, nail distortion
The property symptom: prostate abnormalities, sexal maturity are slow, physiology is smooth, the childbirth obstacle
General symptom: hypoevolutism, poor appetite, yctalopia, easy infection disease, sick and wounded rehabilitation are slow
On the other hand, the effect that can expect by an amount of picked-up zinc is for example as follows.
Stimulation is exempted from service, and is effective to the prevention and the treatment of flu, anti-cancer.
Prevent the aging of the aged macula lutea that causes, prevent to lose one's sight.
Keep the normal function of the sense of taste, sense of smell, vision.
Effective to infertile treatment and prevention, strengthen the male sex's energy, prevent prostatic obstacle.
Suppress histamine and generate antiallergy.
Promote the health of skin, effective to the treatment of bedsore, acne or mange, anti-loss.
Anti-inflammatory effect is arranged, effective to rheumatism or arthritic treatment.
Improve memory, learning ability, relax nervousness or gloomy, effective to the treatment of self-closing disease or Split disease.
In the present invention, zinc then has no particular limits its form so long as can be used as the form that food uses, and for example the form that can contain in food yeast is engaged in this healthy beverage.The healthy beverage of every 720ml cooperates 10mg～100mg zinc.If be less than 10mg, then can not bring into play the effect of this healthy beverage regulation.If surpass 100mg then uneconomical.The use level of preferred zinc is 20mg～50mg.
VI) vitamin C
Ascorbic main function is as follows.
Synthesizing of auxiliary collagen, strengthen skin, blood vessel, mucous membrane, bone.
The reduction of anti-oxidative damage, vitamin E.
The prevention of arterial sclerosis.
Relax chronic fatigue syndrome.
The propagation that suppresses helicobacter pylori (pyloric bacteria).
Prevent dementia.
Illness in eye such as prevention presbyopia, cataract.
Suppress the generation of carcinogen nitrosamine.
Promotion is as synthetic in the body of the interferon of anticancer.
Participate in the conversion of cholesterol to bile acid.
Owing to strengthen leukocytic function, so have antitumaous effect, antivirus action, detoxication.
The synthetic of hemochrome assisted in the absorption of mineral matters such as auxiliary iron or copper.
Participate in the generation of anti-stress hormone (cortex hormone of aadrenaline).
Every 720ml healthy beverage of the present invention preferably adds 500mg～14000mg vitamin C, especially preferably adds 600mg～10000mg.
VII) vitamin B1
Vitamin B1 contains in 200ml milk about 10 quality % of mankind's requirement every day, is included in most food such as cereal or vegetables, fish, meat.But, in rice, be 100 if establish brown rice, polished rice is 19 so, and the tendency of too much picked-up hobby beverage is allegedly arranged recently, finds the vitamin B1 deficiency in the child of growth stage or young man.The function of vitamin B1 is, after sugar was absorbed as glucose, pheron (being synthesized from protein) worked and produce power, and at this moment vitamin B1 or pantothenic acid work as coenzyme.If the B1 deficiency, fatiguability then, anorexia be we can say to be related to and is grown up or neural function.Every 720ml healthy beverage of the present invention preferably adds 2mg～40mg vitamin B1, especially preferably adds 10mg～30mg.
VIII) vitamin B2
Vitamin B2, another name is called " growth vitamin ", with respect to pupil's daily requirement amount, can supply about 30% with 200ml milk.Beyond growing up, also be related to the function of tongue lip skin or eye etc. as can be known, or improve locomitivity.If it is said vitamin B2 deficiency then be related to seborrhagia atopic dermatitis or symptoms such as angular stomatitis, kopiopia, recently, also have it to be called in addition " beauty treatment vitamin ", can be described as for the child of growth stage or young man, women and will note the vitamin that absorbs especially.Every 720ml healthy beverage of the present invention preferably adds 3mg～50mg vitamin B2, especially preferably adds 15mg～40mg.
IX) vitamin B6
Vitamin B6 becomes the center and acts in the metabolism of protein.In addition, for protein transduction being changed into sugar or lipid, or in opposite situation, also work.Vitamin B6 has the effect that makes the normalization of exempting from service, thus except in the treatment of allergy with antihistaminic uses, also have diuresis, detoxication.Also the effect with lipid has relation, if to eat fat constituent then vitamin B6 is consumed not enough more, if continue like this then the situation that becomes fatty liver, cirrhosis, pionemia, arteriosclerosis is arranged.The alcoholic B6 that is deficient in vitamin easily especially.For excreting insulin well, vitamin B6 is necessary in diabetes.Further, also the someone thinks that one of the reason of pregnancy reaction is the vitamin B6 deficiency, not only in the serious occasion of pregnancy reaction, and needs 6 times common vitamin in the gestation.The Cobastab group that contains vitamin B6 influences each other and acts on.Every 720ml healthy beverage of the present invention preferably adds 3mg～50mg vitamin B6, especially preferably adds 15mg～40mg.
X) cobalamin
Cobalamin, be from nineteen twenty-nine to the pernicious anaemia patient give with milk and healthy people's gastric juice then result of treatment well, the vitamin that its function has become clearly.As from wherein distinguish,, in 200ml milk, contain the amount about can the about 25 quality % of supply～50 quality % in a large number with respect to the requirement of every day in people's growth stage.Known cobalamin is pulled together with the folic acid that is contained in a large number in the yellow green vegetables etc., promotes the synthetic of erythrocytic hemochrome, or participates in principal component nucleic acid synthetic of DNA (gene).The deficiency of cobalamin, with cause erythrocytic production unusual wait relevant because erythrocytic hemochrome transports oxygen in whole bodies, so become the reason that energy i (in vivo) production can not fully be carried out.B12 in addition we can say with relationship of nerve closely, and also known have relation with the reparation of nerve ending or the brain of nervous centralis, also can think the balance that participates in memory or spirit.Cobalamin is the same with vitamin B2, can be described as to note the vitamin that absorbs especially in people's growth stage.Every 720ml healthy beverage of the present invention preferably adds 0.3 μ g～7.0 μ g cobalamins, especially preferably adds 1.5 μ g～5.0 μ g.
The water that uses in this healthy beverage can use the pure water that is applicable to the habitual healthy beverage in this field.In this healthy beverage, as required, also can further add the active ingredient of at least a formation of the juice, honey, spices, anticorrisive agent and the colouring agent that are selected from vitamins (for example, vitamin D, E, K etc.), mineral matter class (for example, Mg, Ca, Fe, Cu, Zn, Se etc.), amino acids, peptide class, carbohydrate, water-solubility vegetable fibres, fruit or vegetables beyond the above-mentioned active ingredient, addition at this moment can suitably be selected.
The manufacture method of this healthy beverage has no particular limits, and gets final product so long as not various gradation compositions and the healthy beverage that produces being given with such method and the condition of baneful influence.For example can list the method for in the water of ormal weight, adding other gradation compositions and mixing.
Below by embodiment, further describe the present invention.
Embodiment
The modulation of＜beverage 〉
(embodiment 1) modulates, healthy beverage of the present invention as embodiment according to disclosed proportioning in the following table 1.
The proportioning of table 1 embodiment 1
| Gradation composition | The use level of every 720ml |
| Water-soluble core albumen | 3600mg |
| Collagen | 68g |
| Chondroitin | 115mg |
| Hyaluronic acid | 43mg |
| Zinc | 36mg |
| Vitamin C | 7200mg |
| Vitamin B1 | 22mg |
| Vitamin B2 | 29mg |
| Vitamin B6 | 29mg |
| Cobalamin | 3.6μg |
| The water of other adding ingredients (fructose liquid of glucose sugar/refining honey/pineapple fruit juice/acid flavoring/caramel colorant/anticorrisive agent/spices) and nubbin | In right amount |
(comparative example 1) except from gradation composition except that dezincify, modulate other and the beverage of embodiment 1 identical proportioning, be used as comparative example 1.Following table 2 shows the proportioning of this comparative example 1.
[table 2]
The proportioning of table 2 comparative example 1
| Gradation composition | The use level of every 720ml |
| Water-soluble core albumen | 3600mg |
| Collagen | 68g |
| Chondroitin | 115mg |
| Hyaluronic acid | 43mg |
| Zinc | - |
| Vitamin C | 7200mg |
| Vitamin B1 | 22mg |
| Vitamin B2 | 29mg |
| Vitamin B6 | 29mg |
| Cobalamin | 3.6μg |
| The water of other adding ingredients (fructose liquid of glucose sugar/refining honey/pineapple fruit juice/acid flavoring/caramel colorant/anticorrisive agent/spices) and nubbin | In right amount |
(comparative example 2) modulation has only cooperated the beverage of zinc as active ingredient, and as a comparative example 2.The proportioning that shows this comparative example 2 in the following table 3.
[table 3]
The proportioning of table 3 comparative example 2
| Gradation composition | The use level of every 720ml |
| Water-soluble core albumen | - |
| Collagen | - |
| Chondroitin | - |
| Hyaluronic acid | - |
| Zinc | 76mg |
| Vitamin C | - |
| Vitamin B1 | - |
| Vitamin B2 | - |
| Vitamin B6 | - |
| Cobalamin | - |
| The water of other adding ingredients (fructose liquid of glucose sugar/refining honey/pineapple fruit juice/acid flavoring/caramel colorant/anticorrisive agent/spices) and nubbin | In right amount |
＜evaluation test method 〉
To this healthy beverage (embodiment 1), comparative example 1 and comparative example 2, recruit 50 experimenter (each experimenters respectively, be grouped and make sex ratio, the range of age, mean age much at one), carried out for 4 weeks altogether to absorb the 60ml beverage corresponding every day respectively, following 1 to 24 project is judged with the mode of survey.
1 health improves
2 can be good at sleep (sleep)
Asthma during 3 motions disappears
4 appetite increase
5 pachylosises disappear
6 constipation are eliminated
The root blackening of 7 white hairs
8 acne (thing of emerging) disappear
9 muscle power strengthen
10 WAs sensation is salubrious
The state of 11 stomach and intestine improves
12 nympholepsies
13 disappearances of being still drank after a night
14 is of pink and healthy-looking
15 skin polish
16 bodies and minds become substantial
17 vigour become foot
It is easily bright and clear that 18 moods become
19 moods become leisurely and comfortable
20 are not limited to oneself
21 become when associating with others does not repel
22 dysgeusias are improved
23 hinder the healing easily that becomes
24 apocleisis overfeeding tendency is improved
Judgement is that the project that answer is arranged is collected calculating.
Judging, is that the state during respectively with beginning is compared with the state in the 1st, 2 and 4 weeks after beginning to absorb, with " deterioration " was made as 0 fen, improve the high more method of giving more with high score of tendency, will " recovery from illness " be made as full marks 10 and assign to give a mark, its average mark carries out by calculating.(estimating all is to carry out according to each experimenter's subjectivity).In addition, simultaneously, as overall merit, be with through all impression of duration of test in each project all 0 to 100 minute scope marking, also its average mark judges by calculating.In addition, show the survey paper of employed healthy beverage of the present invention (embodiment 1) among Fig. 1, Fig. 2 shows the survey paper of comparative example 1, and Fig. 3 shows the survey paper of comparative example 2.
＜evaluation test result 〉
Show the evaluation test result relevant in this healthy beverage, following table 4 and table 5 with comparative example 1 and comparative example 2.In addition, the result that will in following table 4 and table 5, put down in writing, separately projects show with chart, so Fig. 4 is to Figure 27 difference display items display 1 to 24 pairing chart.
[table 4]
Table 4 test evaluation result (survey result) its 1
Table 5 test evaluation result (survey result) its 2
From table 4 and table 5, and Fig. 4 can confirm in Figure 27, whole to project 1 to 24 have added the present invention's product (embodiment) of the proportioning of zinc in the proportioning of comparative example 1, the results verification of comparing with comparative example 1 and comparative example 2 shows remarkable excellent results (synergy).Further, embodiment, especially, find surprisingly, to in the effect of thinking outside the effect that zinc proves effective, for example project 2 " can be good at sleep (sleep) ", project 3 " asthma when slightly moving disappears ", project 6 " constipation eliminations ", project 10 " WA is felt clearly " have confirmed to have high synergy.
The simple declaration of figure
[Fig. 1] Fig. 1 is the figure of the survey usefulness paper that shows the present invention's product (embodiment).
[Fig. 2] Fig. 2 is the survey that shows comparative example 1 figure with paper.
[Fig. 3] Fig. 3 is the survey that shows comparative example 2 figure with paper.
[Fig. 4] Fig. 4 is the chart of result in the display items display 1.
[Fig. 5] Fig. 5 is the chart of result in the display items display 2.
[Fig. 6] Fig. 6 is the chart of result in the display items display 3.
[Fig. 7] Fig. 7 is the chart of result in the display items display 4.
[Fig. 8] Fig. 8 is the chart of result in the display items display 5.
[Fig. 9] Fig. 9 is the chart of result in the display items display 6.
[Figure 10] Figure 10 is the chart of result in the display items display 7.
[Figure 11] Figure 11 is the chart of result in the display items display 8.
[Figure 12] Figure 12 is the chart of result in the display items display 9.
[Figure 13] Figure 13 is the chart of result in the display items display 10.
[Figure 14] Figure 14 is the chart of result in the display items display 11.
[Figure 15] Figure 15 is the chart of result in the display items display 12.
[Figure 16] Figure 16 is the chart of result in the display items display 13.
[Figure 17] Figure 17 is the chart of result in the display items display 14.
[Figure 18] Figure 18 is the chart of result in the display items display 15.
[Figure 19] Figure 19 is the chart of result in the display items display 16.
[Figure 20] Figure 20 is the chart of result in the display items display 17.
[Figure 21] Figure 21 is the chart of result in the display items display 18.
[Figure 22] Figure 22 is the chart of result in the display items display 19.
[Figure 23] Figure 23 is the chart of result in the display items display 20.
[Figure 24] Figure 24 is the chart of result in the display items display 21.
[Figure 25] Figure 25 is the chart of result in the display items display 22.
[Figure 26] Figure 26 is the chart of result in the display items display 23.
[Figure 27] Figure 27 is the chart of result in the display items display 24.
Claims (5)
1. a healthy beverage that adds water-soluble core albumen is characterized in that, every 720ml healthy beverage contains
Water-soluble core protein 15 00mg～40000mg,
Collagen 30g～140g,
Chondroitin 50mg～200mg,
Hyaluronic acid 20mg～80mg,
Zinc 10mg～100mg,
Vitamin C 500mg～14000mg,
Vitamin B1 2mg～40mg,
Vitamin B2 3mg～50mg,
Vitamin B6 3mg～50mg,
The water of cobalamin 0.3 μ g～7.0 μ g and other adding ingredients and nubbin,
Above-mentioned water-soluble core albumen is by the nucleoprotein in the fish sperm being carried out the degraded water miscible water-soluble core albumen that becomes, and above-mentioned other adding ingredients are juice, honey, spices, anticorrisive agent and colouring agent at least a that are selected from vitamin D, vitamin E, vitamin K, Mg, Ca, Fe, Cu, Se, amino acids, fructose liquid of glucose sugar, water-solubility vegetable fibres, fruit or vegetables.
2. a healthy beverage that adds water-soluble core albumen is characterized in that, contains in this healthy beverage of every 720ml
Water-soluble core protein 25 00mg～35000mg,
Collagen 60g～100g,
Chondroitin 80mg～150mg,
Hyaluronic acid 30mg～60mg,
Zinc 20mg～50mg,
Vitamin C 600mg～10000mg,
Vitamin B1 10mg～30mg,
Vitamin B2 15mg～40mg,
Vitamin B6 15mg～40mg,
The water of cobalamin 1.5 μ g～5.0 μ g and other adding ingredients and nubbin,
Above-mentioned water-soluble core albumen is by the nucleoprotein in the fish sperm being carried out the degraded water miscible water-soluble core albumen that becomes, and above-mentioned other adding ingredients are juice, honey, spices, anticorrisive agent and colouring agent at least a that are selected from vitamin D, vitamin E, vitamin K, Mg, Ca, Fe, Cu, Se, amino acids, fructose liquid of glucose sugar, water-solubility vegetable fibres, fruit or vegetables.
Adding described in claim 1 or 2 healthy beverage of water-soluble core albumen, it is characterized in that above-mentioned water-soluble core albumen is by becoming water miscible water-soluble core albumen with the nucleoprotein in the fish sperm of dog salmon, trout or catfish is degraded.
4. the healthy beverage that adds water-soluble core albumen as claimed in claim 1 or 2, it is characterized in that, above-mentioned water-soluble core albumen contain more than or equal to 20 quality % with nucleoprotein with resulting oligonucleotides/nucleosides and the oligopeptides after degraded of nuclease and Protease Treatment.
5. the healthy beverage that adds water-soluble core albumen as claimed in claim 3, it is characterized in that, above-mentioned water-soluble core albumen contain more than or equal to 20 quality % with nucleoprotein with resulting oligonucleotides/nucleosides and the oligopeptides after degraded of nuclease and Protease Treatment.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP2004/019605 WO2006070453A1 (en) | 2004-12-28 | 2004-12-28 | Nutritional drink |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1893841A CN1893841A (en) | 2007-01-10 |
| CN100477930C true CN100477930C (en) | 2009-04-15 |
Family
ID=36614580
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004800009570A Active CN100477930C (en) | 2004-12-28 | 2004-12-28 | Health-care drink |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JPWO2006070453A1 (en) |
| CN (1) | CN100477930C (en) |
| WO (1) | WO2006070453A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103874431A (en) * | 2011-10-12 | 2014-06-18 | 福蒂姿株式会社 | Glutathione-containing health drink |
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| CZ18797U1 (en) | 2008-07-08 | 2008-08-11 | Isoline S.R.O. | Composition for prevention of jaoint diseases |
| CN101675804B (en) * | 2008-09-16 | 2013-12-11 | 孙志刚 | Juvenile ABC ODAC composite capsule best nutritional supplement |
| CN101675803B (en) * | 2008-09-16 | 2013-12-11 | 孙志刚 | Composite medical granule for children |
| CN101675805B (en) * | 2008-09-16 | 2013-12-11 | 孙志刚 | Combined capsule for middle-aged and elderly people |
| CN101675806B (en) * | 2008-09-16 | 2013-12-11 | 孙志刚 | Combined capsule for adults |
| JP5844957B2 (en) * | 2009-05-15 | 2016-01-20 | 日祥株式会社 | Beverage |
| JP5377202B2 (en) * | 2009-09-29 | 2013-12-25 | テルモ株式会社 | Food material for fortification |
| CN101690601B (en) * | 2009-09-30 | 2012-07-25 | 贵州卡璐丽卡生物医药科技有限公司 | Roxburgh rose collagen beverage and preparation method thereof |
| JP5377203B2 (en) * | 2009-09-30 | 2013-12-25 | テルモ株式会社 | Postoperative supplementary meal |
| CN103070442B (en) * | 2012-08-09 | 2013-12-25 | 浙江省海洋开发研究院 | Pneumatophorus japonicns polypeptide function beverage and preparation process thereof |
| WO2014114939A1 (en) * | 2013-01-23 | 2014-07-31 | Bottled Science Limited | Skin enhancing beverage composition |
| DE102013213335A1 (en) * | 2013-07-08 | 2015-01-08 | Bwt Aktiengesellschaft | Method and device for providing a composition containing hyaluronic acid |
| CN106107300A (en) * | 2016-07-30 | 2016-11-16 | 铜仁市万山区龙门山泉饮用水有限公司 | A kind of drinking water rich in vitamin |
| CN108888769A (en) * | 2018-07-30 | 2018-11-27 | 郑州兰茜生物工程有限公司 | The biological agent that strengthening tendons are good for network function is used and had to a kind of neck-shoulder pain, lumbago and leg pain |
| CN112566513A (en) * | 2019-07-17 | 2021-03-26 | 上海利统生化制品有限公司 | Edible composition for promoting hair growth and delaying canities |
| WO2021182534A1 (en) * | 2020-03-12 | 2021-09-16 | フォーデイズ株式会社 | Healthy beverage containing water-soluble nucleoprotein |
| JP7284955B2 (en) * | 2020-07-20 | 2023-06-01 | フォーデイズ株式会社 | Neural stem cell proliferation promoting agent and method for promoting neural stem cell proliferation using the same |
| CN113287708A (en) * | 2021-07-12 | 2021-08-24 | 千世泰生物科技(青岛)有限公司 | Solid beverage containing sodium hyaluronate and method for detecting content of sodium hyaluronate in solid beverage |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10109940A (en) * | 1996-08-12 | 1998-04-28 | Taisho Pharmaceut Co Ltd | Composition containing zinc |
| JP2001252048A (en) * | 2000-03-14 | 2001-09-18 | Fancl Corp | Food composition |
| JP2002080379A (en) * | 2000-08-31 | 2002-03-19 | Bizen Chemical Co Ltd | Reproductive function enhancer |
| JP2003325194A (en) * | 2002-03-04 | 2003-11-18 | Showa Denko Kk | Method for producing cyanocarboxylic acid by microorganism |
-
2004
- 2004-12-28 JP JP2006550521A patent/JPWO2006070453A1/en active Pending
- 2004-12-28 CN CNB2004800009570A patent/CN100477930C/en active Active
- 2004-12-28 WO PCT/JP2004/019605 patent/WO2006070453A1/en not_active Application Discontinuation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103874431A (en) * | 2011-10-12 | 2014-06-18 | 福蒂姿株式会社 | Glutathione-containing health drink |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006070453A1 (en) | 2006-07-06 |
| CN1893841A (en) | 2007-01-10 |
| JPWO2006070453A1 (en) | 2008-06-12 |
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