CN100453109C - Medicine composition for treating headache and preparing method - Google Patents
Medicine composition for treating headache and preparing method Download PDFInfo
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- CN100453109C CN100453109C CNB2006100079678A CN200610007967A CN100453109C CN 100453109 C CN100453109 C CN 100453109C CN B2006100079678 A CNB2006100079678 A CN B2006100079678A CN 200610007967 A CN200610007967 A CN 200610007967A CN 100453109 C CN100453109 C CN 100453109C
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Abstract
The present invention relates to a Chinese medicine for effectively curing headache with obvious therapeutic effect. It is made up by using 15 Chinese medicinal materials of American ginseng, gastrodia root, stir-fried ligusticum root, flowery knotweed root, prepared aconite main tube, dahurian angelica root, licorice and others through a certain preparation process.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to a kind of pharmaceutical composition for the treatment of headache.
Background technology
Common headache comprises aching all over the head, migraine; Preceding headache, back headache, top of the head pain; Cluster headache is vascular headache again; Muscular contraction headache, nodositas headache, spastic headache, nervous headache; Rhinogenous headache; Headache caused by ophthalmic diseases; Headache caused by otopathy.The reason multiterminal of headache, but nothing more than diseases caused by exogenous pathogenic factor and internal injury two big classes.Head is " confluence of all yang-channels " " mansion of sun ", is again the brain place, the blood of all the five internal organs elite, and the gas of six internal organs sun is annotated in head on all.The all heresies of all diseases caused by exogenous pathogenic factor, pathogen is delaied, and checks yang-energy, or all diseases of internal injury, causes mechanism of qi contrary disorderly, and obstruction of collaterals by blood stasis, or it is foster to become homeless all directly influences head and a sick obstinate disease takes place.The headache obstinate disease, history records records, three state Cao behaviour i.e. therefore disease, does not control and dead.Or every day regularly show effect, or hand over that joint is sick to be done, or through before must violate, or have seven emotions to stimulate to trigger, send out then severe splitting headache, inflammatory exophthalmos head string, sialemesis, unconsciousness is seemingly slept, diet is all hindered.All this kind must be that " incubative pathogen " haunts." incubative pathogen " because of, must be that patient's healthy energy must be empty, outer excessive six evils attack into, unable bulging heresy is passed through inside, and stays and does not go.Time was both of a specified duration, and by fur, meridians gradually go deep into internal organs, and the dead blood of damp-phlegm builds up nest, and dark volt does not go, and satisfies into obstinate disease.Control method, when putting " incoming road of heresy, the i.e. outlet of heresy " in order, giving treatment in accordance with the tendency of pathological change is set upright gas, game clock is closed, and draws the incubative pathogen place and then recovers thoroughly.
Summary of the invention
The object of the invention is to provide a kind of pharmaceutical composition that the treatment headache is had remarkable result.
The present invention is achieved through the following technical solutions: choose crude drug
Radix Panacis Quinquefolii 9-27 weight portion Rhizoma Gastrodiae 9-27 weight portion Rhizoma Chuanxiong 15-45 weight portion
Radix Polygoni Multiflori 6-18 weight portion Radix Aconiti 6-18 weight portion Radix Angelicae Dahuricae 6-18 weight portion
Rhizoma Et Radix Notopterygii 6-18 weight portion Rhizoma Ligustici 6-18 weight portion Radix Glycyrrhizae 3-9 weight portion
Scolopendra 3-9 weight portion Squama Manis 3-9 weight portion Scorpio 3-9 weight portion
Mirabilitum crystallina 70-230 weight portion Radix Astragali 15-45 weight portion Cornu Cervi Pantotrichum 15-45 weight portion
The optimum ratio of pharmaceutical composition of the present invention is:
Radix Panacis Quinquefolii 18 weight portion Rhizoma Gastrodiaes 18 weight portion Rhizoma Chuanxiongs 30 weight portions
The Radix Polygoni Multiflori 12 weight portion Radix Aconitis 12 weight portion Radixs Angelicae Dahuricae 12 weight portions
Rhizoma Et Radix Notopterygii 12 weight portion Rhizoma Ligusticis 12 weight portion Radix Glycyrrhizaes 6 weight portions
Scolopendra 6 weight portion Squama Maniss 6 weight portion Scorpio 6 weight portions
The Mirabilitum crystallina 150 weight portion Radixs Astragali 30 weight portion Cornu Cervi Pantotrichums 30 weight portions
The preferred Rhizoma Chuanxiong (parched) of described Rhizoma Chuanxiong; The preferred Radix Aconiti Preparata of Radix Aconiti; The Scorpio preferred water is cleaned air dried Scorpio, and Cornu Cervi Pantotrichum is preferably with the Cornu Cervi Pantotrichum of blood.
Preparation of drug combination method of the present invention is: Radix Polygoni Multiflori, Rhizoma Et Radix Notopterygii, the Radix Angelicae Dahuricae, Rhizoma Ligustici, the Radix Astragali, Radix Glycyrrhizae, Radix Aconiti Preparata are added clear water 150-450 weight portion, 0.5-1.5 at a simmer hour, fry in shallow oil 2-4 time repeatedly, medicinal liquid is mixed put into marmite and fried in shallow oil 3 hours, it is standby to be condensed into the thick paste shape; The ethanol that Scolopendra, Squama Manis, Scorpio is added 10 times of amount 70%-95% made it to soak 4-10 days, went medicinal residues to stay its medicinal liquid standby; After again the Cornu Cervi Pantotrichum of all the other Radix Panacis Quinquefoliis, Rhizoma Gastrodiae, Rhizoma Chuanxiong (parched), Mirabilitum crystallina, band blood being pulverized 120 mesh sieves, last two kinds of medicinal liquids are poured in the medicated powder, fully mixed thoroughly, drying is pulverized and is made capsule, tablet or granule.
Pharmaceutical composition of the present invention adds acceptable accessories and makes clinical any dosage form of accepting.As tablet (coated tablet, Film coated tablets, enteric coated tablet, buccal tablet, dispersible tablet, oral cavity disintegration tablet), capsule, soft capsule, oral liquid, syrup, granule, pill, powder, spray, unguentum, injection, injection lyophilized powder, injection infusion solutions, suppository, drop pill, slow releasing preparation or controlled release preparation etc.
Drug regimen of the present invention is to treatment aching all over the head, migraine; Preceding headache, back headache, top of the head pain, vascular headache, muscular contraction headache, the nodositas headache, spastic headache, satisfactory effects such as nervous headache, rhinogenous headache, headache caused by ophthalmic diseases, headache caused by otopathy, and short treating period, instant effect, with strong points, the cure rate height, the anti-recurrence effect is strong.
Following experimental example is used to further specify the present invention:
The present invention's " quick-acting capsules that effect a permanent cure of the dizzy fiber crops of ten thousand pains " all types of headache obstinate disease 1000 examples of treatment all obtain satisfactory effect, now report as follows:
1, clinical data
Among the clinical observation 1000 routine patients, male 312 examples, women 688 examples; Minimum 6 years old of age, maximum 80 years old, average 36 years old.Sick time reaches 40 years most, the shortest person 3 months.Vascular 236 examples, nerve 289 examples; Eye source property 56 examples; Nasal 315 examples; Ear source property 12 examples; Traumatic cerebral concussion sequela 8 examples, wherein 84 examples of the headache due to the unknown cause.
2, diagnostic criteria
All case all meets the diagnostic criteria of national regulation, all through head CT or EEG (electrocardiogram) examination no abnormality seen, gets rid of organic disease.
3, Therapeutic Method
3.1 square medicine is formed Radix Panacis Quinquefolii 18 grams, Rhizoma Gastrodiae 18 grams, Rhizoma Chuanxiong (parched) 30 grams, Radix Polygoni Multiflori 12 grams, Radix Aconiti Preparata 12 grams, the Radix Angelicae Dahuricae 12 grams, Rhizoma Et Radix Notopterygii 12 grams, Rhizoma Ligustici 12 grams, Radix Glycyrrhizae 6 grams, Scolopendra 6 grams, Squama Manis 6 grams, Scorpio 6 grams, Mirabilitum crystallina 150 grams, the Radix Astragali 30 grams, Cornu Cervi Pantotrichum 30 grams
3.2 washing Scorpio, the medicine making dries; Radix Polygoni Multiflori, Rhizoma Et Radix Notopterygii, the Radix Angelicae Dahuricae, Rhizoma Ligustici, the Radix Astragali, Radix Glycyrrhizae, Radix Aconiti Preparata add clear water 300ml, and 1 hour at a simmer, fry in shallow oil repeatedly 3 times, three medicinal liquids are mixed put into marmite, fry in shallow oil that to be condensed into the thick paste shape after 3 hours standby; The ethanol that Scolopendra, Squama Manis, Scorpio is added 10 times of amounts 95% made it to soak seven days, went medicinal residues to stay its medicinal liquid standby; After again the Cornu Cervi Pantotrichum of all the other Radix Panacis Quinquefoliis, Rhizoma Gastrodiae, Rhizoma Chuanxiong (parched), Mirabilitum crystallina, band blood being pulverized 120 mesh sieves, last two kinds of medicinal liquids are poured in the medicated powder, fully mixed thoroughly, be placed on and make it to dry under the sun and then pulverize standby.
3.3 capsule is made the above-mentioned dry back medicated powder 0# capsule of packing into, 0.5 gram/grain.Seal standby.
3.4 instructions of taking every day 3 times, use this capsule of honey tea mixing in water for oral taking 4-6 grain after meal.Serveing on 7 days is a course of treatment.(every is 0.5 gram)
4, criterion of therapeutical effect
Recovery from illness: after 1-2 course of therapy, headache is felt sick, and not recurrence in the 1a is followed up a case by regular visits in simultaneous phenomenon complete obiterations such as tending to vomit and insomnia;
Produce effects: after 1-2 course of therapy, headache disappears substantially, and simultaneous phenomenon obviously alleviates, and can adhere to work, and idol had extremely of short duration headache when only spiritedness was nervous or tired;
Take a turn for the better: after 1-2 course of therapy, the headache degree obviously alleviates, and attack times obviously reduces, and the persistent period shortens, and patient can tolerate;
Invalid: after 1-2 course of therapy, headache and simultaneous phenomenon are not seen improvement.
4, therapeutic outcome
The present invention treats among the various headache 1000 routine patients, 890 examples of fully recovering (accounting for 89%), produce effects 90 examples (accounting for 9%), 12 examples that take a turn for the better (accounting for 1.2%), invalid 8 examples (accounting for 0.8%).Total effective rate 99.2%.
5, model case
Case 1: the king * *, woman, 39 years old, on March 6th, 1992 examined, and patient right side migraine was shown effect 20 years repeatedly, and One's head is splitting, pain connects order system, pain is nausea and vomiting very then, can alleviate every monthly outbreak 3-5 time after about 4-5 hour, repeatedly treat through Chinese and western drugs, hundred methods are invalid, seemingly have to be ill throughout one's life, to stubbornly refusing headache more.The headache of nearly 1 year persistence, aggravation day by day, pain as being stabbed, paroxysmal is had a headache entirely, and be the pollex sample and beat, dizzy poor appetite, spiritlessness and weakness, light red tongue is dark, white and thin fur and moisten stringy and tense pulse.Card genus ailment said due to cold or exposure is held cold-damp under the arm and is gone into apoplex involving the channels and collaterals, qi depression to blood stasis, disorder of meridian-QI for a long time.With the present invention " spy grinds the quick-acting capsules that effect a permanent cure of the dizzy fiber crops of ten thousand pains ", 0.5g * 4 balls uses light honey tea mixing in water for oral taking 3 times every day after meal, the obstinate disease of having a headache the same day of taking medicine obviously alleviates, and this medicine serve on January, and dizziness, headache, numb limbs and tense tendons all disappear, the patient is as the sun shines again after the rain sample frankness, and spirit is also taken on an entirely new look.Continue one week of clothes,, stop the recurrence again of back day to consolidate curative effect.Follow up a case by regular visits to again after 2 years, persistent ailment headache in several years shows effect from the end.
Case 2: Liu *, woman, 60 years old.Suffered from headaches insomnia, forgetful, poor appetite 11 years.Again because of feelings will stimulates, headache aggravates before 2 months, and two temples pain such as bore spines are lain awake all night.Disconnected in provincial hospital's argument for nervous headache, through not feeling any better with Chinese and western drugs symptomatic treatments such as flunarizine, nimodipine, carbamazepine, VitB1, VitB6, oryzanol.Obey 6 of capsules of the present invention, every day 3 taking medicine after meales.Having a headache after the patient took medicine 4 hours subtracts greatly, feels on the head that cold air outwards directly emits, and filters in the abdomen and makes a sound, sleeping gradually.Serveing on 5 days all disease trouble removes.Follow up a case by regular visits to recurrence at the year ends 10.
Following embodiment is used to further specify the present invention:
Embodiment 1:
Radix Panacis Quinquefolii 18kg Rhizoma Gastrodiae 18kg Rhizoma Chuanxiong (parched) 30kg Radix Polygoni Multiflori 12kg
Radix Aconiti Preparata 12kg Radix Angelicae Dahuricae 12kg Rhizoma Et Radix Notopterygii 12kg Rhizoma Ligustici 12kg
Radix Glycyrrhizae 6kg Scolopendra 6kg Squama Manis 6kg Scorpio 6kg
Mirabilitum crystallina 150kg Radix Astragali 30kg Cornu Cervi Pantotrichum 30kg
Scorpio washed dry; Radix Polygoni Multiflori, Rhizoma Et Radix Notopterygii, the Radix Angelicae Dahuricae, Rhizoma Ligustici, the Radix Astragali, Radix Glycyrrhizae, Radix Aconiti Preparata add clear water 300ml, and 1 hour at a simmer, fry in shallow oil repeatedly 3 times, three medicinal liquids are mixed put into marmite and fried in shallow oil 3 hours, it is standby to be condensed into the thick paste shape; The ethanol that Scolopendra, Squama Manis, Scorpio is added 10 times of amounts 95% made it to soak seven days, went medicinal residues to stay its medicinal liquid standby; After again the Cornu Cervi Pantotrichum of all the other Radix Panacis Quinquefoliis, Rhizoma Gastrodiae, Rhizoma Chuanxiong (parched), Mirabilitum crystallina, band blood being pulverized 120 mesh sieves, last two kinds of medicinal liquids are poured in the medicated powder, fully mixed thoroughly, be placed on and make it to dry and then pulverize dress 0# capsule, 0.5 gram/grain under the sun.Every day 3 times, use this capsule of honey tea mixing in water for oral taking 4-6 grain after meal.Serveing on 7 days is a course of treatment.
Embodiment 2:
Radix Panacis Quinquefolii 13kg Rhizoma Gastrodiae 23kg Rhizoma Chuanxiong (parched) 20kg Radix Polygoni Multiflori 15kg
Radix Aconiti Preparata 9kg Radix Angelicae Dahuricae 15kg Rhizoma Et Radix Notopterygii 9kg Rhizoma Ligustici 15kg
Radix Glycyrrhizae 4kg Scolopendra 8kg Squama Manis 4kg Scorpio 8kg
Mirabilitum crystallina 100kg Radix Astragali 40kg Cornu Cervi Pantotrichum 20kg
Said medicine technology is routinely made oral liquid.
Embodiment 3:
Radix Panacis Quinquefolii 23kg Rhizoma Gastrodiae 13kg Rhizoma Chuanxiong 40kg Radix Polygoni Multiflori 9kg
Radix Aconiti 15kg Radix Angelicae Dahuricae 9kg Rhizoma Et Radix Notopterygii 15kg Rhizoma Ligustici 9kg
Radix Glycyrrhizae 8kg Scolopendra 4kg Squama Manis 8kg Scorpio 4kg
Mirabilitum crystallina 200kg Radix Astragali 20kg Cornu Cervi Pantotrichum 40kg
Said medicine technology is routinely made injection.
Embodiment 4:
Radix Panacis Quinquefolii 18kg Rhizoma Gastrodiae 18kg Rhizoma Chuanxiong 30kg Radix Polygoni Multiflori 12kg
Radix Aconiti 12kg Radix Angelicae Dahuricae 12kg Rhizoma Et Radix Notopterygii 12kg Rhizoma Ligustici 12kg
Radix Glycyrrhizae 6kg Scolopendra 6kg Squama Manis 6kg Scorpio 6kg
Mirabilitum crystallina 150kg Radix Astragali 30kg Cornu Cervi Pantotrichum 30kg
Said medicine add conventional adjuvant routinely technology make lyophilized injectable powder.
Embodiment 5:
Radix Panacis Quinquefolii 13kg Rhizoma Gastrodiae 23kg Rhizoma Chuanxiong 20kg Radix Polygoni Multiflori 15kg
Radix Aconiti 9kg Radix Angelicae Dahuricae 15kg Rhizoma Et Radix Notopterygii 9kg Rhizoma Ligustici 15kg
Radix Glycyrrhizae 4kg Scolopendra 8kg Squama Manis 4kg Scorpio 8kg
Mirabilitum crystallina 100kg Radix Astragali 40kg Cornu Cervi Pantotrichum 20kg
Said medicine add conventional adjuvant routinely technology make slow releasing preparation.
Embodiment 6:
Radix Panacis Quinquefolii 23kg Rhizoma Gastrodiae 13kg Rhizoma Chuanxiong (parched) 40kg Radix Polygoni Multiflori 9kg
Radix Aconiti Preparata 15kg Radix Angelicae Dahuricae 9kg Rhizoma Et Radix Notopterygii 15kg Rhizoma Ligustici 9kg
Radix Glycyrrhizae 8kg Scolopendra 4kg Squama Manis 8kg Scorpio 4kg
Mirabilitum crystallina 200kg Radix Astragali 20kg Cornu Cervi Pantotrichum 40kg
Said medicine add conventional adjuvant routinely technology make drop pill.
Embodiment 7:
Radix Panacis Quinquefolii 18kg Rhizoma Gastrodiae 18kg Rhizoma Chuanxiong 30kg Radix Polygoni Multiflori 12kg
Radix Aconiti 12kg Radix Angelicae Dahuricae 12kg Rhizoma Et Radix Notopterygii 12kg Rhizoma Ligustici 12kg
Radix Glycyrrhizae 6kg Scolopendra 6kg Squama Manis 6kg Scorpio 6kg
Mirabilitum crystallina 150kg Radix Astragali 30kg Cornu Cervi Pantotrichum 30kg
Said medicine add conventional adjuvant routinely technology make spray.
Embodiment 8:
Radix Panacis Quinquefolii 13kg Rhizoma Gastrodiae 23kg Rhizoma Chuanxiong 20kg Radix Polygoni Multiflori 15kg
Radix Aconiti 9kg Radix Angelicae Dahuricae 15kg Rhizoma Et Radix Notopterygii 9kg Rhizoma Ligustici 15kg
Radix Glycyrrhizae 4kg Scolopendra 8kg Squama Manis 4kg Scorpio 8kg
Mirabilitum crystallina 100kg Radix Astragali 40kg Cornu Cervi Pantotrichum 20kg
Said medicine technology is routinely made unguentum.
Embodiment 9:
Radix Panacis Quinquefolii 23kg Rhizoma Gastrodiae 13kg Rhizoma Chuanxiong 40kg Radix Polygoni Multiflori 9kg
Radix Aconiti 15kg Radix Angelicae Dahuricae 9kg Rhizoma Et Radix Notopterygii 15kg Rhizoma Ligustici 9kg
Radix Glycyrrhizae 8kg Scolopendra 4kg Squama Manis 8kg Scorpio 4kg
Mirabilitum crystallina 200kg Radix Astragali 20kg Cornu Cervi Pantotrichum 40kg
Said medicine technology is routinely made suppository.
Claims (15)
1, a kind of pharmaceutical composition for the treatment of headache is characterized in that this combination made by following crude drug:
Radix Panacis Quinquefolii 9-27 weight portion Rhizoma Gastrodiae 9-27 weight portion Rhizoma Chuanxiong 15-45 weight portion
Radix Polygoni Multiflori 6-18 weight portion Radix Aconiti 6-18 weight portion Radix Angelicae Dahuricae 6-18 weight portion
Rhizoma Et Radix Notopterygii 6-18 weight portion Rhizoma Ligustici 6-18 weight portion Radix Glycyrrhizae 3-9 weight portion
Scolopendra 3-9 weight portion Squama Manis 3-9 weight portion Scorpio 3-9 weight portion
Mirabilitum crystallina 70-230 weight portion Radix Astragali 15-45 weight portion Cornu Cervi Pantotrichum 15-45 weight portion.
2, pharmaceutical composition according to claim 1 is characterized in that said composition made by following crude drug:
Radix Panacis Quinquefolii 18 weight portion Rhizoma Gastrodiaes 18 weight portion Rhizoma Chuanxiongs 30 weight portions
The Radix Polygoni Multiflori 12 weight portion Radix Aconitis 12 weight portion Radixs Angelicae Dahuricae 12 weight portions
Rhizoma Et Radix Notopterygii 12 weight portion Rhizoma Ligusticis 12 weight portion Radix Glycyrrhizaes 6 weight portions
Scolopendra 6 weight portion Squama Maniss 6 weight portion Scorpios 6 weight portions
The Mirabilitum crystallina 150 weight portion Radixs Astragali 30 weight portion Cornu Cervi Pantotrichums 30 weight portions.
3, pharmaceutical composition according to claim 1 is characterized in that said composition made by following crude drug:
Radix Panacis Quinquefolii 13 weight portion Rhizoma Gastrodiaes 23 weight portion Rhizoma Chuanxiongs 20 weight portions
The Radix Polygoni Multiflori 15 weight portion Radix Aconitis 9 weight portion Radixs Angelicae Dahuricae 15 weight portions
Rhizoma Et Radix Notopterygii 9 weight portion Rhizoma Ligusticis 15 weight portion Radix Glycyrrhizaes 4 weight portions
Scolopendra 8 weight portion Squama Maniss 4 weight portion Scorpios 8 weight portions
The Mirabilitum crystallina 100 weight portion Radixs Astragali 40 weight portion Cornu Cervi Pantotrichums 20 weight portions.
4, pharmaceutical composition according to claim 1 is characterized in that said composition made by following crude drug:
Radix Panacis Quinquefolii 23 weight portion Rhizoma Gastrodiaes 13 weight portion Rhizoma Chuanxiongs 40 weight portions
The Radix Polygoni Multiflori 9 weight portion Radix Aconitis 15 weight portion Radixs Angelicae Dahuricae 9 weight portions
Rhizoma Et Radix Notopterygii 15 weight portion Rhizoma Ligusticis 9 weight portion Radix Glycyrrhizaes 8 weight portions
Scolopendra 4 weight portion Squama Maniss 8 weight portion Scorpios 4 weight portions
The Mirabilitum crystallina 200 weight portion Radixs Astragali 20 weight portion Cornu Cervi Pantotrichums 40 weight portions.
5,, it is characterized in that described Rhizoma Chuanxiong is a Rhizoma Chuanxiong (parched) according to the described pharmaceutical composition of one of claim 1-4; Radix Aconiti is a Radix Aconiti Preparata; Scorpio is the Cornu Cervi Pantotrichum of band blood for the clean air dried Scorpio of washing, Cornu Cervi Pantotrichum.
6, preparation of drug combination method according to claim 5, it is characterized in that this method is for adding clear water 150-450 weight portion with Radix Polygoni Multiflori, Rhizoma Et Radix Notopterygii, the Radix Angelicae Dahuricae, Rhizoma Ligustici, the Radix Astragali, Radix Glycyrrhizae, Radix Aconiti Preparata, 0.5-1.5 at a simmer hour, fry in shallow oil 2-4 time repeatedly, medicinal liquid mixed put into marmite and fried in shallow oil 3 hours, it is standby to be condensed into the thick paste shape; The ethanol that Scolopendra, Squama Manis, Scorpio is added 10 times of amount 70%-95% made it to soak 4-10 days, went medicinal residues to stay its medicinal liquid standby; After again the Cornu Cervi Pantotrichum of all the other Radix Panacis Quinquefoliis, Rhizoma Gastrodiae, Rhizoma Chuanxiong (parched), Mirabilitum crystallina, band blood being pulverized 120 mesh sieves, last two kinds of medicinal liquids are poured in the medicated powder, fully mixed thoroughly, drying is pulverized and is made capsule, tablet or granule.
7, preparation of drug combination method according to claim 6 is characterized in that this method is Scorpio to be washed dry; Radix Polygoni Multiflori, Rhizoma Et Radix Notopterygii, the Radix Angelicae Dahuricae, Rhizoma Ligustici, the Radix Astragali, Radix Glycyrrhizae, Radix Aconiti Preparata add clear water 300 bulking value parts, and 1 hour at a simmer, fry in shallow oil repeatedly 3 times, three medicinal liquids are mixed put into marmite and fried in shallow oil 3 hours, it is standby to be condensed into the thick paste shape; The ethanol that Scolopendra, Squama Manis, Scorpio is added 10 times of amounts 95% made it to soak seven days, went medicinal residues to stay its medicinal liquid standby; After again the Cornu Cervi Pantotrichum of all the other Radix Panacis Quinquefoliis, Rhizoma Gastrodiae, Rhizoma Chuanxiong (parched), Mirabilitum crystallina, band blood being pulverized 120 mesh sieves, last two kinds of medicinal liquids are poured in the medicated powder, fully mixed thoroughly, be placed on and make it under the sun to dry and then pulverize, make capsule.
8, pharmaceutical composition according to claim 5, its feature is in being that adding conventional adjuvant by practice of pharmacy makes the tablet of clinical acceptance, capsule, oral liquid, granule, pill, powder, spray, unguentum, injection or suppository.
9, pharmaceutical composition according to claim 5, its feature is in being that adding conventional adjuvant by practice of pharmacy makes the soft capsule of clinical acceptance, syrup, drop pill or injection lyophilized powder.
10, pharmaceutical composition according to claim 5, its feature is in being to add the injection infusion solutions that conventional adjuvant is made clinical acceptance by practice of pharmacy.
11, pharmaceutical composition according to claim 5, its feature is in being to add the slow releasing preparation that conventional adjuvant is made clinical acceptance by practice of pharmacy.
12, pharmaceutical composition according to claim 5, its feature is in being to add the controlled release preparation that conventional adjuvant is made clinical acceptance by practice of pharmacy.
13, pharmaceutical composition according to claim 8, its feature is in being that described tablet is coated tablet, Film coated tablets or enteric coated tablet.
14, pharmaceutical composition according to claim 8, its feature is in being that described tablet is buccal tablet or dispersible tablet.
15, the application of pharmaceutical composition according to claim 5 in preparation treatment headache medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100079678A CN100453109C (en) | 2006-02-24 | 2006-02-24 | Medicine composition for treating headache and preparing method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100079678A CN100453109C (en) | 2006-02-24 | 2006-02-24 | Medicine composition for treating headache and preparing method |
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| CN101024041A CN101024041A (en) | 2007-08-29 |
| CN100453109C true CN100453109C (en) | 2009-01-21 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111686235A (en) * | 2020-08-10 | 2020-09-22 | 河南中医药大学 | Traditional Chinese medicine composition for treating parietal headache |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1015356B (en) * | 1985-03-20 | 1992-02-05 | 株式会社东京龙野 | Fuel delivery display and control system |
| CN1112424A (en) * | 1993-11-12 | 1995-11-29 | 丁木 | Toutongning-medicine for headache |
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2006
- 2006-02-24 CN CNB2006100079678A patent/CN100453109C/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1015356B (en) * | 1985-03-20 | 1992-02-05 | 株式会社东京龙野 | Fuel delivery display and control system |
| CN1112424A (en) * | 1993-11-12 | 1995-11-29 | 丁木 | Toutongning-medicine for headache |
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| CN101024041A (en) | 2007-08-29 |
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