CN100448472C - Chinese medicinal formulation for treating pulmonary tuberculosis - Google Patents
Chinese medicinal formulation for treating pulmonary tuberculosis Download PDFInfo
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- CN100448472C CN100448472C CNB2006100512594A CN200610051259A CN100448472C CN 100448472 C CN100448472 C CN 100448472C CN B2006100512594 A CNB2006100512594 A CN B2006100512594A CN 200610051259 A CN200610051259 A CN 200610051259A CN 100448472 C CN100448472 C CN 100448472C
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Abstract
The invention relates to a Chinese medicinal preparation for treating phthisis which is prepared from Anemone davidii Franch. 30-50, bletilla tuber 25-35, humulus scandens merr 15-25 and gingko leaf 10-15 through conventional methods of medicine production. The medicament can be prepared into powders, capsules and pills.
Description
Technical field
Patent of the present invention relates to a kind of Chinese medicine preparation, relates in particular to the phthisical Chinese medicine preparation of a kind of treatment.
Background technology
Pulmonary tuberculosis is to have communicable pulmonary chronic, weak property illness, is commonly encountered diseases, frequently-occurring disease, ancient claim " pulmonary tuberculosis ", and symptom was its basic feature with " cough, spitting of blood, hectic fever, night sweat, become thin ", to mankind's harm more thousand.Because the appearance of chemotherapeutics, this disease was once once controlled, and in the last few years, because the generation of the Resistant strain of pulmonary tuberculosis pathogenic bacteria makes this ancient disease revivable again, according to the preliminary statistics, China's number of patients every year was with 1% speed increment.Analyze its reason, as the phthisical medicine of treatment in the prior art mainly is streptomycin, isoniazid, pyrazinamide, rifampicin etc., these medicines are big to the toxicity of accepting pulmonary tuberculosis treatment patient, the patient who has is the toxicity that can not tolerate Western medicine, and be interrupted, interrupt or drug withdrawal voluntarily, what have then is can not or to be reluctant to obey Western medicine because of the disease of liver or other system, but observing of many patient's strictnesses also the arranged principle of medication of " early stage; an amount of; rule; associating; whole process " of doctor trained in Western medicine chemotherapeutic, but still can not thoroughly cure the result of the generation of the morbific Resistant strain of pulmonary tuberculosis that Here it is.In recent years this phenomenon is known through research is clear in medical circle, tuberculosis is divided A, B, four kinds of floras of C, D, A group's metabolism is vigorous, easily killed by chemotherapeutic, B, C group's poor metabolism, be difficult for being killed by chemotherapeutic, D group is in static resting state, chemotherapy is inoperative, can only rely on immune function of human body and control, the patient of immunologic hypofunction, its phagocyte can not be eliminated intracellular tulase effectively, form granulomatous lesion, this infected macrophage not only can not be eliminated infectious bacteria, infects flora on the contrary at its growth and breeding.Can prove that by above immunity is the key point that human body is defeated tuberculosis.So when adopting drug treatment, because the generation of Resistant strain in recent years, what display is that therapeutic effect is not remarkable, add medicine-feeding valency height, the rural area has many people cannot afford to consult a doctor, and can not eat many-sided reason such as medicine and makes and patient's number of this disease rise year by year.
For to various pneumonopathy or phthisical treatment aspect, in motherland's traditional Chinese medical science treasure-house, many prescriptions and proved recipe are arranged, introducing the phthisical Chinese medicine of a kind of treatment as application number CN99116345.1 title " the phthisical Chinese medicine of a kind of treatment ", mainly is drawbacks such as costing an arm and a leg of overcoming that existing Western medicine exists, toxic side effect, curative effect be relatively poor.The prescription that it includes has the Radix Stemonae, Bulbus Lilii, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Platycodonis, Radix Polygalae, Fructus Mori, the Radix Astragali, Rhizoma Polygonati, Fructus Lycii, Radix Curcumae, Semen Nelumbinis, longan pulp, Radix Ophiopogonis, Radix Asparagi, Radix Codonopsis, Radix Rehmanniae Preparata, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Rhizoma Imperatae, Colla Corii Asini, Herba Houttuyniae, Cordyceps, Gecko, Radix Glycyrrhizae.Be mainly used in treatment pulmonary tuberculosis and pulmonary cavity, also can treat bronchiectasis, diseases such as spitting of blood, tuberculosis of breast, lymphoid tuberculosis.Application number is arranged in addition for the CN98123926.9 name is called " Chinese herbal medicine of treatment pulmonary tuberculosis ", application number is called " the phthisical Chinese medicine of a kind of treatment ", application number CN00112927.9 for the CN98115357.7 name, name is called " the phthisical Chinese herbal medicine of a kind of treatment " patent and has also introduced the application of some treatment pulmonary tuberculosis.
The present invention seeks to develop one and be exclusively used in the phthisical Chinese medicine preparation of treatment, require the good absorbing of this medicine, easy to carry, expense is lower, the cure rate height, have no side effect, on the basis of inheriting former generation's proved recipe, study for a long period of time through the inventor, by the practice of self, constantly sum up and innovation, invented the phthisical Chinese medicine preparation of this special for treating, be mainly powder, capsule, pill.
Summary of the invention
Below be concrete summary of the invention,
The phthisical Chinese medicine preparation of a kind of treatment, the composition of its medicine is that the prescription by mass ratio is a Rhizoma anemones davidii 30～50: Pseudobulbus Bletillae (Rhizoma Bletillae) 25～35: Herba humuli scandentis 15～25: Herba Bulbophylli Odoratissim 10～15, the phthisical Chinese medicine preparation of this treatment can be made according to the conventional production method of Chinese medicine patent medicine, above the indication Chinese medicine preparation mean powder, capsule, pill.
More than treat phthisical Chinese medicine preparation, the composition mass ratio of its medicine is a Rhizoma anemones davidii 40: Pseudobulbus Bletillae (Rhizoma Bletillae) 30: Herba humuli scandentis 20: Herba Bulbophylli Odoratissim 10.
More than treat phthisical Chinese medicine preparation, the manufacture method of its powder, pill, capsule is with its pulverize separately of each medicine, be ground into fine powder, sieve, then according to its composition quality than Rhizoma anemones davidii 30～50: Pseudobulbus Bletillae (Rhizoma Bletillae) 25～35: Herba humuli scandentis 15～25: Herba Bulbophylli Odoratissim 10～15, weighing respectively, uniform mixing, packing promptly obtain powder; On the powder basis, promptly get capsule, powder is added distilled water, adjuvant commonly used make the ball shape and pack and promptly obtain pill with capsulation.
The treatment pulmonary tuberculosis must be abideed by the doctor's advice prescription and take medicine, or/1～3 skies of general 3～6 grams of being grown up, and the children amount is the adult's 1/2nd.
Below the Chinese medicine of medicine composition is in the present invention done some introductions:
Rhizoma anemones davidii: another name, Rhizoma seu herba Asystasiellae Chinensis connects, red synthetism connects, starve tiger, ZUANGUFENG, blood crow etc.Be ranunculaceae plant southwest Anemone cathayensis Kitag. rhizome and leaf.Plant is a perennial herb, and is high about 40～60 centimetres.Nature and flavor: bitter, warm.Function cures mainly: invigorate blood circulation, pain relieving, detumescence, detoxify, control traumatic injury, rheumatalgia, aphtha, furunculosis of the buttock." Chinese medicine voluminous dictionary " 1985.5 months the 1st edition.P2163.
Pseudobulbus Bletillae (Rhizoma Bletillae): another name, the Pseudobulbus Bletillae (Rhizoma Bletillae), sweet, Bletilla striata (Thunb.ex A.Murray)Rchb.f., pleionebulbocodioides rolfe, white clam.Tuber for the orchid Pseudobulbus Bletillae (Rhizoma Bletillae).Perennial herb, about 30～70 centimetres of Gao Keda.Nature and flavor: bitter sweet, cool.Go into lung meridian.Function cures mainly: tonifying the lung, hemostasis, detumescence, granulation promoting, hold back skin ulcer.Control lung and hinder hemoptysis, epistaxis, diseases such as ulcer sore pain." Chinese medicine voluminous dictionary " 1985.5 months the 1st edition.P667.
Herba Bulbophylli Odoratissim: different name stone string orchid.Be orchid Herba Bulbophylli inconspicui and congener, the perennial evergreen draft, happiness is given birth on rock seam or the tree, all herbal medicine.Nature and flavor: sweet light, cool.Function cures mainly: moistening the lung and resolving phlegm, promoting the circulation of QI to relieve pain.Control pulmonary tuberculosis, spitting of blood, chronic tracheitis, chronic pharyngitis, hernia pain etc." Chinese medicine voluminous dictionary " 1985.5 months the 1st edition.P1361.
Herba humuli scandentis; Different name is reined in grass, Ge Leman, Caulis Momordicae Charantiae, is drawn rattan etc.Herb for the moraceae plants Herba humuli scandentis.Be annual or perennial climing property draft, long number rice has barb perverse, and leaf is to life.Nature and flavor: sweet in the mouth is nontoxic.Function cures mainly: clearing away heat and promoting diuresis, gonorrhea is controlled in repercussive, detoxifcation, dysuria. malaria, diarrhoea, dysentery, pulmonary tuberculosis, lung abscess, pneumonia etc." Chinese medicine voluminous dictionary " 1985.5 months the 1st edition.P2313.
Above Chinese medicine is for stating clearly avirulence on " Chinese medicine voluminous dictionary " 1985.5 months the 1st edition.
The crude drug source of Chinese medicine preparation of the present invention is wide, and lower, the good absorbing of expense is easy to carry, is convenient to preserve, and the cure rate height has no side effect.This side possesses general adaptability.This medication journey was generally 3～9 months, and the minority refractory pulmonary tuberculosis is arranged, and reached 12 months most, was everlasting and took effect about two weeks, in 102 examples of clinical treatment, cured 96 examples, accounted for 94.1%, and 6 examples that take a turn for the better account for 5.9%, in the clinical trial, did not have invalid case.
The present invention is the phthisical Chinese medicine preparation of a kind of treatment, can be applicable to various pneumonopathy, phthisical treatment, prove through former generation and inventor's clinical practice for many years, compare with the treatment pneumonopathy of other types, phthisical Chinese and western drugs, this medicine has no side effect to the medication person, and has curative effect certainly, medicine for treatment to shorter, instant effect, the characteristics of the price cheapness of medicine.Simultaneously, the inventor carried out research and practice, the taboo of taking of having found out this medicine according to the property of medicine, the pharmacology of used Chinese medicine, when this Chinese medicine preparation is taken, be not taken by pregnant women, avoid edible living, cold, pungent group food, prohibit and drink, smoke, have a rest to avoid producing disadvantageous physiological metabolism reaction more.
The specific embodiment
Embodiment, with Rhizoma anemones davidii, Pseudobulbus Bletillae (Rhizoma Bletillae), Herba humuli scandentis, Herba Bulbophylli Odoratissim pulverize separately be fine powder to sieving, get Rhizoma anemones davidii 400g, Pseudobulbus Bletillae (Rhizoma Bletillae) 300g, Herba humuli scandentis 200g, Herba Bulbophylli Odoratissim 100g, divide pouch-packaged behind the uniform mixing, promptly obtain powder; On the powder basis, promptly get capsule with capsulation, with powder add suitable distilled water, adjuvant commonly used can be made watered pill shape or honey pill agent, row packing again, the pulmonary tuberculosis medicine just can obtain medical treatment.The treatment pulmonary tuberculosis must be abideed by the doctor's advice prescription and take medicine, powder/1～3 skies of general 3～5 grams of being grown up, and the children amount is 1/2nd of adult's amount, pill is according to the relatively more definite dosage of manufacturing specification.
Clinical case is to the explanation of curative effect of the present invention:
For many years, on the basis of inheriting former generation and inventor's clinical practice for many years, carry out statistical analysis when adopting above-mentioned Chinese medicine preparation to treat to the many cases person of seeing a doctor who accepts for medical treatment, based on capsule and pill, 102 routine pulmonary tuberculosis patients are treated obtain notable therapeutic effect, also carried out observing and following up a case by regular visits to later on to treating patient, existing with summary of interrelated data do.Amount to the patient who cures and produce effects is arranged, cure rate is about more than 94%.
Clinical data
1, patient's type: comprehensive case 102 examples, primary pulmonary tuberculosis 12 examples, infiltrative type 55 examples, chronic fibrotic cavitys type 25 examples, 10 examples are other types, wherein infiltrative type is maximum.
2, diagnosis basis: according to medical history, clinical symptoms, sign, chemical examination and X ray examination are made a definite diagnosis.Difficult patient still needs and does further to check by B ultrasonic, CT.
3, previously treat history: this organizes 102 examples, and the diagnosis and treatment patient substantially makes a definite diagnosis and treated at large hospital, once regular chemotherapy person's 35 examples, irregular chemotherapy person's 66 examples.
4, Therapeutic Method:
Based on capsule and pill, some patients are generally 6～JIUYUE the course of treatment, small number of patients can extend to 12 months.
5, curative effect determinate standard
Decide according to " the disease therapeuticing effect evaluation criteria " of Ministry of Public Health formulation in 1981:
The A recovery from illness: clinical symptom disappearance, expectorant tulase continue feminine gender and reach more than 1 year, and the conducting lung X-ray examination performance belongs to the inactivity focus, and follow-up observation did not still have activeness more than 1 year.
B takes a turn for the better: possess a following person, the more preceding absorption of pathological changes takes a turn for the better, and the cavity dwindles closure, and the expectorant tulase reduces or turns out cloudy.
C is invalid: expectorant bacterium and X ray examination, all do not have the changer before and after the treatment.
Therapeutic outcome: comprehensive case 102 examples, cure 96 examples, account for 94.1%, 6 examples that take a turn for the better account for 5.9%, and the course of treatment is the shortest 3 months, and is the longest 12 months, follow-up observation 1～2 year.
Now curing case with regard to some is set forth in down:
Case 1, Deng, the man, 40 years old, suffer from " cavernous pulmonary tuberculosis ", once about half a year, failed all the time to cure before 2004 at Liuzhi Special Region hospital regular treatment, after be interrupted again and take medicine, the state of an illness increases the weight of gradually, liver function damage.So change the request treatment by Chinese herbs, the inventor takes capsule of the present invention to him, patient's cough after February, tachypnea, sputum mixed with blood, chest pain, night sweat symptom show and subtract, low grade fever is eliminated, and the more preceding improvement of diet is imitated more not square, the patient continues to take this medicine, all disappears through 3 months all symptoms.Repeatedly film making proof pulmonary tuberculosis is all fully recovered, and liver function has been recovered normally, follows up a case by regular visits to 2 years rabat, expectorant and cultivates no abnormality seen.
Case 2 is revived certain, the man, 25 years old, the peasant suffered from " fibro-cavitative pulmonary tuberculosis " and once crossed some months at hospital's regular treatment before 2004, after again from obeying traditional herbal medicine, the state of an illness fails to cure all the time, often cough, spitting of blood, chest pain, night sweat, spirit and appetite are very poor, general weakness arrives the inventor place upon somebody's introduction, takes capsule of the present invention, after 3 months, the patient has cough when removing, and above-mentioned symptom disappears substantially, checks empty the reparation through film making, calcification has appearred, medicine takes effect, after 6 months, and patient's disappearance of coughing, have rosy cheeks, spirit and diet are very good, followed up a case by regular visits to patient's rabat 1 year, expectorant is cultivated normal always.
Case 3, Zhu, man, 32 years old, married, suffer from " cavernous pulmonary tuberculosis ", once in the diagnosis and treatment of Liuzhi Special Region hospital, failed about 1 year to cure before 2005, its interruption is taken medicine, the state of an illness increases the weight of gradually, asks treatment by Chinese herbs so change, and the inventor takes capsule of the present invention to him, patient's cough behind the first quarter moon, tachypnea, sputum mixed with blood, chest pain, night sweat symptom show and subtract, low grade fever is eliminated, the more preceding improvement of diet, and the patient continues to take this medicine, process all symptoms half a year all disappear, the pulmonary tuberculosis of repeatedly making film is all fully recovered, and liver function has been recovered normally to follow up a case by regular visits to no abnormality seen half a year.
Case 4, leaf, man, 50 years old, the peasant suffers from " infiltrative pulmonary tuberculosis ", before 2002 once in the Puding County hospitalize about 1 year, fail to cure, after be interrupted again and take medicine, the state of an illness increases the weight of gradually, the people introduces and finds the inventor, and the inventor takes capsule of the present invention after giving his diagnosis and treatment, patient's cough after 1 month, tachypnea, sputum mixed with blood, chest pain, night sweat symptom show and subtract, and low grade fever is eliminated, the more preceding improvement of diet, through adjusting dose, the patient continues to take this medicine, all disappears through all symptoms of some months.The pulmonary tuberculosis of repeatedly making film is all fully recovered, and follows up a case by regular visits to through 1 year and does not see rabat, expectorant cultivation unusually.
Claims (3)
1, the phthisical Chinese medicine preparation of a kind of treatment, it is characterized in that preparation is that prescription by mass ratio is a Rhizoma anemones davidii 30～50: Pseudobulbus Bletillae (Rhizoma Bletillae) 25～35: Herba humuli scandentis 15～25: Herba Bulbophylli Odoratissim 10～15, the phthisical Chinese medicine preparation of this treatment is made according to the conventional production method of Chinese medicine patent medicine.
2, the phthisical Chinese medicine preparation of a kind of treatment according to claim 1 is characterized in that the prescription of its Chinese medicine preparation is a Rhizoma anemones davidii 40 by mass ratio: Pseudobulbus Bletillae (Rhizoma Bletillae) 30: Herba humuli scandentis 20: Herba Bulbophylli Odoratissim 10.
3, the phthisical Chinese medicine preparation of a kind of treatment according to claim 1 is characterized in that wherein production method is to make according to the conventional production method of Chinese medicine patent medicine, above the agent of obtaining through refining mean Chinese medicine for oral administration powder, capsule, pill.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100512594A CN100448472C (en) | 2006-10-30 | 2006-10-30 | Chinese medicinal formulation for treating pulmonary tuberculosis |
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2006100512594A CN100448472C (en) | 2006-10-30 | 2006-10-30 | Chinese medicinal formulation for treating pulmonary tuberculosis |
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| CN1966000A CN1966000A (en) | 2007-05-23 |
| CN100448472C true CN100448472C (en) | 2009-01-07 |
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| CNB2006100512594A Expired - Fee Related CN100448472C (en) | 2006-10-30 | 2006-10-30 | Chinese medicinal formulation for treating pulmonary tuberculosis |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104998071A (en) * | 2015-07-02 | 2015-10-28 | 贵阳中医学院 | Compound preparation ofherb of dense flower Bulbophyllum and preparation and detection method for said compound preparation |
| CN105412379A (en) * | 2015-12-09 | 2016-03-23 | 刘传新 | Inhalation-type phthisis treatment preparation and preparing method thereof |
| CN107714940A (en) * | 2017-10-12 | 2018-02-23 | 汪昔林 | One kind treats phthisical Chinese medicine |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1386535A (en) * | 2002-06-11 | 2002-12-25 | 范忠智 | Medicine for treating tuberculosis |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1386535A (en) * | 2002-06-11 | 2002-12-25 | 范忠智 | Medicine for treating tuberculosis |
Non-Patent Citations (2)
| Title |
|---|
| 老年肺结核126例诊治分析. 杜延玲等.陕西医学杂志，第32卷第4期. 2003 |
| 老年肺结核126例诊治分析. 杜延玲等.陕西医学杂志，第32卷第4期. 2003 * |
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| CN1966000A (en) | 2007-05-23 |
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