CN100444873C - Chinese medicinal formulation for treating spermophlebectasia - Google Patents
Chinese medicinal formulation for treating spermophlebectasia Download PDFInfo
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- CN100444873C CN100444873C CNB2006101548220A CN200610154822A CN100444873C CN 100444873 C CN100444873 C CN 100444873C CN B2006101548220 A CNB2006101548220 A CN B2006101548220A CN 200610154822 A CN200610154822 A CN 200610154822A CN 100444873 C CN100444873 C CN 100444873C
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- varicocele
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Abstract
The invention relates to a Chinese medicinal preparation for treating spermophlebectasia, wherein the reactive constituents are prepared from the following raw materials (by weight portion): ledebouriella root 6-12, dahurian angelica root 6-9, dried orange peel 8-10, red peony root 6-9, Chinese angelica root 9-12, pangolin scales 9-12, Chinese honey locust 9-12, myrrh 3-5, licorice root 4-6, honeysuckle flower 10-15, root of Chinese trichosannthes 10-15, bupleurum root 4-6, Sichuan fritillary bulb 9-12, frank incense 3-6, phellodendron bark 8-10, plantain seeds 8-10. The medicament can be prepared into dose forms of oral liquids, capsules, tablets, pills or powders.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, relate to a kind of Chinese medicine preparation for the treatment of varicocele more specifically, be suitable for treating the constitutional varicocele.
Background technology
Varicocele is that spermatic vein backflow obstruction or valve failure blood reflux cause that the blood stasis of blood stagnates, and causes the tortuous expansion of climing shape vein.Sickness rate is 10-15% in male crowd, is more common in person between twenty and fifty.In the male sterility crowd, account for 15-20%.The constitutional varicocele, except form that cancer is fastened or retroperitoneal neoplasms compressing, hydronephrosis or ectopic vessel etc. cause the Secondary cases varicocele in the postcava, the left side spermatic vein meets at right angles and refluxes in renal veins, lacks factors such as valve or valve insufficiency and cause internal spermatic vein blood reflux, the expansion of pampiniform plexus congestion.Because spermatic vein expansion, testis, the epididymis inner blood stasis of blood stagnate, anoxia and toxic metabolite are piled up, and hinder spermatogenesis and maturation, thereby have caused male infertility.Suffer from this disease patient when standing scrotum swell, the heavy bob sense of expanding is arranged, can be to hypogastric region, groin or waist radiation, the standing for a long time postemphasis alleviates after the flat bed rest.
Present treatment present situation, for varicocele with sterile or dysspermatism person, have manifest symptom person to adopt operative treatment.Medication effect is not good.
Summary of the invention
It is a kind of treatment constitutional varicocele Chinese medicine preparation that purpose of the present invention provides, and its active component is made by following materials of weight proportions: Radix Saposhnikoviae 6-12, Radix Angelicae Dahuricae 6-9, Pericarpium Citri Reticulatae 8-10, Radix Paeoniae Rubra 6-9, Radix Angelicae Sinensis 9-12, stir-baked SQUAMA MANITIS 9-12, Spina Gleditsiae 9-12, Myrrha 3-5, Radix Glycyrrhizae 4-6, Flos Lonicerae 10-15, Radix Trichosanthis 10-15, Radix Bupleuri 4-6, Bulbus Fritillariae Thunbergii 9-12, Olibanum 3-6, Cortex Phellodendri 8-10, Semen Plantaginis 8-10.
The medicine of the present invention preparation is one of following dosage form: oral liquid, capsule, tablet, pill, powder.
In above-mentioned preparation was formed, Flos Lonicerae contained chlorogenic acid, isochlorogenic acid, Flavonoid substances, lonicerin, inositol and trace volatilization wet goods, and Bulbus Fritillariae Thunbergii contains
SteroidThe alcohol Alkaloid contains protein, polysaccharide, amino acids etc., and Radix Trichosanthis contains protein, polysaccharide, amino acids etc., and Radix Glycyrrhizae contains triterpenoid saponin glycyrrhizin (being glycyrrhizin), also contains compositions such as reducing sugar, starch and colloid.Flos Lonicerae, Bulbus Fritillariae Thunbergii, Radix Trichosanthis, the effect of Radix Glycyrrhizae heat clearing away eliminating stagnation.Radix Angelicae Sinensis contains ligustilide, n-butene lactone, angelicone, carvacrol etc., Radix Paeoniae Rubra contains paeoniflorin, peony lactone glycoside, oxypaeoniflorin, benzoylpaeoniflorin, the lucky ketone of Radix Paeoniae, Lactiflorin., daucosterol etc., Olibanum is resinous, gummy, the volatilization wet goods, Myrrha is resinous,, volatile oil (main be eugenol, a phenyl methylcarbamate etc.), natural gum (separating into arabinose, galactose and xylose etc.) etc.Radix Angelicae Sinensis, Radix Paeoniae Rubra, Olibanum, the effect of Myrrha promoting blood circulation to remove blood stasis.Stir-baked SQUAMA MANITIS contains protein, inorganic salt etc., and Spina Gleditsiae contains gleditschiasaponin B-G, Palmic acid, hard ester acid, oleic acid, Asia
SteroidAlcohol, sitosterol, nonacosane etc.Stir-baked SQUAMA MANITIS, the Spina Gleditsiae detumescence effect of assaulting fortified position.Pericarpium Citri Reticulatae contains volatile oil, and main component is d-limonen, citral etc. in the oil.Flavone compound etc.; The effect of regulating the flow of vital energy.Radix Saposhnikoviae contains volatile oil, mannitol, bitterness glycoside, phenols, polysaccharide and organic acid etc., and the Radix Angelicae Dahuricae contains isoimperatorin, imperatorin), bergapton, phellopterin, oxypeucedanin etc.Radix Saposhnikoviae, the Radix Angelicae Dahuricae are walked meridians and all medicines of row.Cortex Phellodendri contains berberine, phellodendrine, obakulactone, obacunone, magnoflorine, palm leaf coculine etc., and Semen Plantaginis contains volume phlegmatic temperament, aucubin, and contains plantenolic acid, choline, adenine, succinic acid, resin etc.Cortex Phellodendri, Semen Plantaginis diarrhea Jiao's fire action.Radix Bupleuri contains Saikosaponin a～d, and contains spinach sterol, stigmasterol, △ 22-stigmastenol, admitol) and a small amount of volatile oil; Priming is gone into Liver Channel.Full side reaches the effect of removing blood stasis with potent drugs detoxicating and resolving stagnation of pathogens.
Advantage of the present invention is: can not only promoting flow of QI and blood, heat-clearing and toxic substances removing, soothing the liver dissipating depression of QI, improve the circulation of spermatic cord, testis inner blood, effectively relief of symptoms, improve sperm survival rate, and energy and blood of human body and the five internal organs physiological function are had coordinated balance, regulating functional activities of qi reaches the purpose of treatment must aim at the pathogenesis of disease.The present invention can improve or eliminate constitutional varicocele clinical symptoms and male infertility, follows up a case by regular visits to according to the outpatient service curative effect, and clinical malaise symptoms improves or the disappearance effective percentage can reach 82%, cures the male infertility effective percentage and reaches 46%.And have that dosage is light, determined curative effect, short treating period, cure rate height, reduce advantages such as relapse rate, side effect are little.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment.
Embodiment 1
Prescription and each ingredients weight parts ratio are: Radix Saposhnikoviae 7, the Radix Angelicae Dahuricae 7, Pericarpium Citri Reticulatae 7, Radix Paeoniae Rubra 7, Radix Angelicae Sinensis 10, stir-baked SQUAMA MANITIS 12, Spina Gleditsiae 12, Myrrha 3, Radix Glycyrrhizae 5, Flos Lonicerae 12, Radix Trichosanthis 12, Radix Bupleuri 5, Bulbus Fritillariae Thunbergii 12, Olibanum 3, Cortex Phellodendri 10, Semen Plantaginis 10.
After said components taken by weighing by weight, with raw material routinely oral liquid process make oral liquid.
Embodiment 2
Prescription and each ingredients weight parts ratio are: Radix Saposhnikoviae 9, the Radix Angelicae Dahuricae 9, Pericarpium Citri Reticulatae 10, Radix Paeoniae Rubra 8, Radix Angelicae Sinensis 12, stir-baked SQUAMA MANITIS 10, Spina Gleditsiae 9, Myrrha 3, Radix Glycyrrhizae 4, Flos Lonicerae 10, Radix Trichosanthis 12, Radix Bupleuri 4, Bulbus Fritillariae Thunbergii 12, Olibanum 3, Cortex Phellodendri 8, Semen Plantaginis 8.
After said components taken by weighing by weight, with raw material routinely the honeyed pill production technology make honeyed pill.
Embodiment 3
Prescription and each ingredients weight parts ratio are: Radix Saposhnikoviae 8, the Radix Angelicae Dahuricae 8, Pericarpium Citri Reticulatae 10, Radix Paeoniae Rubra 9, Radix Angelicae Sinensis 12, stir-baked SQUAMA MANITIS 12, Spina Gleditsiae 10, Myrrha 3, Radix Glycyrrhizae 4, Flos Lonicerae 10, Radix Trichosanthis 12, Radix Bupleuri 4, Bulbus Fritillariae Thunbergii 9, Olibanum 5, Cortex Phellodendri 8, Semen Plantaginis 8.
After said components taken by weighing by weight, with raw material routinely tablet manufacturing technology make tablet.
Embodiment 4
Prescription and each ingredients weight parts ratio are: Radix Saposhnikoviae 12, the Radix Angelicae Dahuricae 9, Pericarpium Citri Reticulatae 10, Radix Paeoniae Rubra 9, Radix Angelicae Sinensis 12, stir-baked SQUAMA MANITIS 12, Spina Gleditsiae 10, Myrrha 5, Radix Glycyrrhizae 6, Flos Lonicerae 15, Radix Trichosanthis 15, Radix Bupleuri 6, Bulbus Fritillariae Thunbergii 12, Olibanum 6, Cortex Phellodendri 10, Semen Plantaginis 10.
After said components taken by weighing by weight, with raw material routinely capsule manufacture technology make capsule.
Embodiment 5
Prescription and each ingredients weight parts ratio are: Radix Saposhnikoviae 10, the Radix Angelicae Dahuricae 8, Pericarpium Citri Reticulatae 10, Radix Paeoniae Rubra 9, Radix Angelicae Sinensis 12, stir-baked SQUAMA MANITIS 10, Spina Gleditsiae 9, Myrrha 5, Radix Glycyrrhizae 6, Flos Lonicerae 15, Radix Trichosanthis 12, Radix Bupleuri 6, Bulbus Fritillariae Thunbergii 12, Olibanum 6, Cortex Phellodendri 10, Semen Plantaginis 10.
After said components taken by weighing by weight, with raw material routinely the powder production technology make powder.
Embodiment 6
It is patient's 100 examples of constitutional varicocele that the oral liquid for the treatment of excess syndrome example 1 preparation is selected clinical diagnosis, takes oral liquid, and medication dose is according to variations such as age, body weight, disease severities, every day 2 times, each 10-30ml, 3 weeks were a course of treatment, followed up a case by regular visits to 36 months.Curative effect judging standard: clinical symptom disappearance, seminal fluid recover normal, do not have recurrence after the drug withdrawal, are clinical cure; Clinical symptom relief or seminal fluid transfer to well effectively; Only clinical symptom relief is for alleviating.Result: cure 42 examples, cure rate 42%; Effective 19 examples, effective percentage 19%; Remission 21 examples, remission rate 21%; Total effective rate reaches 82%.
Need not further to explain in detail to tell, believe and adopt the disclosed content in front, those skilled in the art can use the present invention to greatest extent.Therefore, the embodiment of front only is interpreted as to illustrating, but not limits the scope of the invention in any form.
Claims (2)
1. Chinese medicine preparation for the treatment of varicocele, it is characterized in that: its active component is made by following materials of weight proportions:
Radix Saposhnikoviae 6-12 Radix Angelicae Dahuricae 6-9 Pericarpium Citri Reticulatae 8-10 Radix Paeoniae Rubra 6-9
Radix Angelicae Sinensis 9-12 stir-baked SQUAMA MANITIS 9-12 Spina Gleditsiae 9-12 Myrrha 3-5
Radix Glycyrrhizae 4-6 Flos Lonicerae 10-15 Radix Trichosanthis 10-15 Radix Bupleuri 4-6
Bulbus Fritillariae Thunbergii 9-12 Olibanum 3-6 Cortex Phellodendri 8-10 Semen Plantaginis 8-10.
2. a kind of Chinese medicine preparation for the treatment of varicocele according to claim 1, the medicine of preparation are one of following dosage form: oral liquid, capsule, tablet, pill or powder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006101548220A CN100444873C (en) | 2006-11-23 | 2006-11-23 | Chinese medicinal formulation for treating spermophlebectasia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006101548220A CN100444873C (en) | 2006-11-23 | 2006-11-23 | Chinese medicinal formulation for treating spermophlebectasia |
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| Publication Number | Publication Date |
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| CN1965991A CN1965991A (en) | 2007-05-23 |
| CN100444873C true CN100444873C (en) | 2008-12-24 |
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| CNB2006101548220A Expired - Fee Related CN100444873C (en) | 2006-11-23 | 2006-11-23 | Chinese medicinal formulation for treating spermophlebectasia |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101199792B (en) * | 2007-12-17 | 2010-12-01 | 朱红民 | Medicament compound for treating varicocele |
| CN101199794B (en) * | 2007-12-17 | 2010-10-20 | 邓兰芹 | Medicament for treating spermatic funicle vein cirsoid |
| CN101204455B (en) * | 2007-12-19 | 2012-05-30 | 赵秀荣 | Chinese traditional medicine preparation for curing varicocele |
| CN109288979A (en) * | 2018-11-16 | 2019-02-01 | 南京长江医院集团有限公司 | Sheng Jing Yu Zi Tang |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1583111A (en) * | 2004-06-04 | 2005-02-23 | 刘俊清 | Chinese medicine for varicose vein |
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2006
- 2006-11-23 CN CNB2006101548220A patent/CN100444873C/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1583111A (en) * | 2004-06-04 | 2005-02-23 | 刘俊清 | Chinese medicine for varicose vein |
Non-Patent Citations (4)
| Title |
|---|
| 中医治疗精索静脉曲张不育症研究进展. 李其信.广西中医药，第26卷第1期. 2003 |
| 中医治疗精索静脉曲张不育症研究进展. 李其信.广西中医药，第26卷第1期. 2003 * |
| 加味仙方活命饮治疗精液不液化症76例. 韩松豹.四川中医，第23卷第7期. 2005 |
| 加味仙方活命饮治疗精液不液化症76例. 韩松豹.四川中医，第23卷第7期. 2005 * |
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| CN1965991A (en) | 2007-05-23 |
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Granted publication date: 20081224 Termination date: 20111123 |