CN100421711C - Chinese medicinal composition for treating urinamid - Google Patents
Chinese medicinal composition for treating urinamid Download PDFInfo
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- CN100421711C CN100421711C CNB2006101462179A CN200610146217A CN100421711C CN 100421711 C CN100421711 C CN 100421711C CN B2006101462179 A CNB2006101462179 A CN B2006101462179A CN 200610146217 A CN200610146217 A CN 200610146217A CN 100421711 C CN100421711 C CN 100421711C
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- medulla
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- 239000000203 mixture Substances 0.000 title claims description 7
- 239000003814 drug Substances 0.000 claims abstract description 13
- 210000002826 placenta Anatomy 0.000 claims abstract description 8
- 241000283898 Ovis Species 0.000 claims description 10
- 241000282894 Sus scrofa domesticus Species 0.000 claims description 10
- 241000756943 Codonopsis Species 0.000 claims description 7
- 239000002994 raw material Substances 0.000 claims description 4
- 208000037157 Azotemia Diseases 0.000 abstract description 6
- 208000009852 uremia Diseases 0.000 abstract description 4
- 235000017166 Bambusa arundinacea Nutrition 0.000 abstract 1
- 235000017491 Bambusa tulda Nutrition 0.000 abstract 1
- 241001330002 Bambuseae Species 0.000 abstract 1
- 235000015334 Phyllostachys viridis Nutrition 0.000 abstract 1
- 210000003056 antler Anatomy 0.000 abstract 1
- 239000011425 bamboo Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 238000009835 boiling Methods 0.000 description 3
- 230000007423 decrease Effects 0.000 description 3
- 239000012467 final product Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 208000001647 Renal Insufficiency Diseases 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 229940109239 creatinine Drugs 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 201000006370 kidney failure Diseases 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 208000001889 Acid-Base Imbalance Diseases 0.000 description 1
- 208000010444 Acidosis Diseases 0.000 description 1
- 208000012639 Balance disease Diseases 0.000 description 1
- 208000022461 Glomerular disease Diseases 0.000 description 1
- 206010027336 Menstruation delayed Diseases 0.000 description 1
- 206010037601 Pyelonephritis chronic Diseases 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 230000018199 S phase Effects 0.000 description 1
- 241001601725 Sthenias Species 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- PNNCWTXUWKENPE-UHFFFAOYSA-N [N].NC(N)=O Chemical compound [N].NC(N)=O PNNCWTXUWKENPE-UHFFFAOYSA-N 0.000 description 1
- 230000007950 acidosis Effects 0.000 description 1
- 208000026545 acidosis disease Diseases 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 235000013877 carbamide Nutrition 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 208000020832 chronic kidney disease Diseases 0.000 description 1
- 201000006368 chronic pyelonephritis Diseases 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- 231100000880 dysequilibrium Toxicity 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 206010029446 nocturia Diseases 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
A Chinese medicine for treating uremia is prepared from 12 Chinese-medicinal materials including pilose asiabell root, human placenta, pilose antler, bamboo leaf, etc.
Description
(1) technical field under
The present invention relates to the uremic Chinese medicine composition of a kind of treatment, belong to technical field of Chinese medicine.
(2) background technology
Uremia shows as chronic kidney to decline brownly clinically, refers to that various late period, chronic kidney disease caused the organismic internal environment steady statue to be destroyed, metabolite retention and a kind of syndrome of producing.With azotemia, water and the unrest of electrolyte metabolism rate and the infringement of acid base imbalance multisystem is main performance.Its person in middle and old age's renal function brown mortality rate that declines is higher.
For carbamide disease, remove to adopt and correct dysequilibrium and acidosis, outside the measures such as minimizing nitrogen metabolism product retention, the success rate of dialysis therapy and renal transplantation is existing to be improved, but most patient is had only mitigation, can not thoroughly eradicate.And, the expense height, general family does not afford to do.
(3) summary of the invention
The present invention provides a kind of evident in efficacy in order to overcome the deficiency of above technology, and side effect is little, the uremic Chinese medicine composition of the treatment that expense is low.
The invention discloses the uremic Chinese medicine composition of a kind of treatment, is to be made by the raw material of following components by weight percent,
Radix Codonopsis 10-20g Placenta Hominis 10-20g Medulla Junci 10-20g Cortex Phellodendri 10-20g
Radix Gentianae 10-20g Cornu Cervi Pantotrichum 5-10g Folium Bambusae 10-20g Radix Cyathulae 5-10g
1 pair of Herba Taraxaci 5-10g Medulla sus domestica 30-50g Medulla Bovis seu Bubali 30-50g Ren caprae seu ovis.
Above-mentioned preparation method of Chinese medicine is: with Radix Codonopsis, and Placenta Hominis, Medulla Junci, Cortex Phellodendri, Radix Gentianae, Cornu Cervi Pantotrichum, Folium Bambusae, Radix Cyathulae, Herba Taraxaci merges, and decocts with water twice, and it is standby to merge decoction liquor.Medulla sus domestica, Medulla Bovis seu Bubali, Ren caprae seu ovis chopping add above-mentioned decoction liquor, boil to get final product.
Instructions of taking: Medulla sus domestica, Medulla Bovis seu Bubali and Ren caprae seu ovis and the decoction liquor of boiling are divided into two parts, sooner or later service once.
Below for the clinical experiment of medicine of the present invention (embodiment 2):
1. case is selected
The standard that this group 64 examples are all formulated based on Bei Dai River meeting in 1977, reference is KerrShi reclassify method in the world, is observation index with four of endogenous creatinine clearance rate (Ccr) creatinine (Cr) blood urea nitrogen (BUN) and specific symptom etc.
I phase (renal insufficiency phase): Ccr reduces, Cr2.0-3.0mg%,, BUN20-35mg%, nocturia increases.
II phase (azotemia phase): Ccr20-50%, and see vomiting, anemia.
The III phase (uremia's phase): Ccr＜20%, Cr＞5.0mg%, BUN＞60mg% has uremia's clinical manifestation.
2. physical data
Choose 64 routine patients altogether, carry out clinical treatment in the People's Hospital, Lixia District, Jinan City year May in March, 2002 to 2005.Male's 38 examples wherein, women's 26 examples.Age 20-39 year 16 examples; 40-59 year 30 examples; 18 examples more than 60 years old; 49 years old mean age.Primary disease is primary glomerulopathy person 33 examples, accounts for 51%; Chronic pyelonephritis 13 examples; Account for 20%.The renal failure degree belongs to I phases 17 example, accounts for 26.6%; II phases 30 example accounts for 46.8%, and III phases 17 example accounts for 26.6%.The medical history of this group case is all more than three months.
3. analysis of cases:
64 routine patients all have deficient syndrome (the spleen deficiency of kidney-QI and the hepatic and renal YIN deficiency) and blood stasis disease simultaneously.The standard card aspect belongs to wet type person's 8 examples of being stranded, and accounts for 12.5%, and water wet type 21 examples account for 32.8%; Upward gush of turbid YIN type 21 examples account for 32.8%; Liver-Yang sthenia type 14 examples account for 21.9%.
4. Therapeutic Method:
Get the Chinese medicine of the invention described above, after making by above-mentioned preparation method, be divided into two parts.Oral, sooner or later respectively once.The Ninth Heaven is a course of treatment, totally three courses of treatment.
5. curative effect judging standard
Curative effect is divided produce effects, takes a turn for the better and invalid three classes.
Produce effects: symptom is alleviated substantially or is disappeared, and BUN recovers normal or more than the decline 15mg%, more than the Cr decline 1.5mg%.
Take a turn for the better: doing well,improving, BUN and Cr descend, but do not reach These parameters or no change.
Invalid: symptom does not have improvement or development, BUN and Cr no change or rising is arranged.
6. therapeutic outcome and analysis
Among the 64 routine patients, treatment back produce effects 33 examples, 21 examples that take a turn for the better, invalid 10 examples.Obvious effective rate is 51.6%, and total effective rate is 84.4%.
The relation of age and curative effect: in 64 examples, 46 examples below 60 years old, obvious effective rate 71.7%; (containing 60 years old) 18 examples more than 60 years old, 2 routine produce effects, 10 examples take a turn for the better.
7. conclusion: the uremic Chinese medicine composition of treatment of the present invention, have evident in efficacyly, side effect is little, the advantage that expense is low.
(4) specific embodiment
Embodiment 1:
Present embodiment is dosage every day by following raw material, decocts by the following method.
Radix Codonopsis 20g Placenta Hominis 15g Medulla Junci 10g Cortex Phellodendri 20g
Radix Gentianae 10g Cornu Cervi Pantotrichum 5g Folium Bambusae 20g Radix Cyathulae 10g
1 pair of Herba Taraxaci 5g Medulla sus domestica 40g Medulla Bovis seu Bubali 40g Ren caprae seu ovis.
Above-mentioned preparation method of Chinese medicine is: with Radix Codonopsis, and Placenta Hominis, Medulla Junci, Cortex Phellodendri, Radix Gentianae, Cornu Cervi Pantotrichum, Folium Bambusae, Radix Cyathulae, Herba Taraxaci merges, and decocts with water twice, and it is standby to merge decoction liquor.Medulla sus domestica, Medulla Bovis seu Bubali, Ren caprae seu ovis chopping add above-mentioned decoction liquor, boil to get final product.
Instructions of taking: Medulla sus domestica, Medulla Bovis seu Bubali and Ren caprae seu ovis and the decoction liquor of boiling are divided into two parts, sooner or later service once.
Embodiment 2:
Present embodiment is dosage every day by following raw material, decocts by the following method.
Radix Codonopsis 15g Placenta Hominis 15g Medulla Junci 15g Cortex Phellodendri 15g
Radix Gentianae 15g Cornu Cervi Pantotrichum 8g Folium Bambusae 15g Radix Cyathulae 8g
1 pair of Herba Taraxaci 8g Medulla sus domestica 40g Medulla Bovis seu Bubali 40g Ren caprae seu ovis.
Above-mentioned preparation method of Chinese medicine is: with Radix Codonopsis, and Placenta Hominis, Medulla Junci, Cortex Phellodendri, Radix Gentianae, Cornu Cervi Pantotrichum, Folium Bambusae, Radix Cyathulae, Herba Taraxaci merges, and decocts with water twice, and it is standby to merge decoction liquor.Medulla sus domestica, Medulla Bovis seu Bubali, Ren caprae seu ovis chopping add above-mentioned decoction liquor, boil to get final product.
Instructions of taking: Medulla sus domestica, Medulla Bovis seu Bubali and Ren caprae seu ovis and the decoction liquor of boiling are divided into two parts, sooner or later service once.
Claims (1)
1. treat uremic Chinese medicine composition for one kind, it is characterized in that: be to make by the raw material of following components by weight percent,
Radix Codonopsis 10-20g Placenta Hominis 10-20g Medulla Junci 10-20g Cortex Phellodendri 10-20g
Radix Gentianae 10-20g Cornu Cervi Pantotrichum 5-10g Folium Bambusae 10-20g Radix Cyathulae 5-10g
1 pair of Herba Taraxaci 5-10g Medulla sus domestica 30-50g Medulla Bovis seu Bubali 30-50g Ren caprae seu ovis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006101462179A CN100421711C (en) | 2006-12-13 | 2006-12-13 | Chinese medicinal composition for treating urinamid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006101462179A CN100421711C (en) | 2006-12-13 | 2006-12-13 | Chinese medicinal composition for treating urinamid |
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|---|---|
| CN100998797A CN100998797A (en) | 2007-07-18 |
| CN100421711C true CN100421711C (en) | 2008-10-01 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2006101462179A Expired - Fee Related CN100421711C (en) | 2006-12-13 | 2006-12-13 | Chinese medicinal composition for treating urinamid |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102793902B (en) * | 2012-08-03 | 2013-10-02 | 王淑玲 | Preparation method for traditional Chinese medicine used for treatment of kidney and yin deficient type acute glomerulonephritis |
| CN102836295B (en) * | 2012-08-21 | 2014-06-11 | 闵红霞 | Medicine for uremia treatment and preparation method |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1256931A (en) * | 1998-12-15 | 2000-06-21 | 魏国栋 | Traditional Chinese medicine for treating uremia and fortifying kidney and productive method thereof |
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- 2006-12-13 CN CNB2006101462179A patent/CN100421711C/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1256931A (en) * | 1998-12-15 | 2000-06-21 | 魏国栋 | Traditional Chinese medicine for treating uremia and fortifying kidney and productive method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 陈以平教授膏方治疗肾病的经验. 李旭，饶克瑯.上海中医药杂志，第38卷第1期. 2004 |
| 陈以平教授膏方治疗肾病的经验. 李旭，饶克瑯.上海中医药杂志，第38卷第1期. 2004 * |
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| CN100998797A (en) | 2007-07-18 |
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Effective date of registration: 20090306 Address after: Shandong Province, Yucheng high tech Development Zone, East Ring Road No. 1 Patentee after: Baolingbao Biology Co., Ltd. Address before: No. ten, No. 4, Lixia Qu, Lixia District, Ji'nan, Shandong Patentee before: Cen Ming |
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Owner name: BAOLINGBAO BIOLOGY CO., LTD. Free format text: FORMER OWNER: CEN MING Effective date: 20090306 |
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Granted publication date: 20081001 Termination date: 20151213 |
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