CN100392058C - Fruit wine containing nano-SOD and its preparation method - Google Patents
Fruit wine containing nano-SOD and its preparation method Download PDFInfo
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- CN100392058C CN100392058C CNB2004100209901A CN200410020990A CN100392058C CN 100392058 C CN100392058 C CN 100392058C CN B2004100209901 A CNB2004100209901 A CN B2004100209901A CN 200410020990 A CN200410020990 A CN 200410020990A CN 100392058 C CN100392058 C CN 100392058C
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Abstract
The present invention relates to nanometer SOD fruit wine and a preparation method thereof. After the fruit wine is prepared, nanometer SOD of 500-2000 active units is added into each kilogram of the fruit wine, and is sufficiently and uniformly mixed. Therefore, the fruit wine is industrialization food whose components can sufficiently display human bodies' defense functions, regulate the physiological rhythm, prevent diseases and promote rehabilitation functions. The present invention solves the application limitation and the defect of the existing biologic proteinase, such as SOD, etc., and opens a new gate for the wide application of the SOD. The present invention has the characteristics of easy popularization, low alcoholicity, rich nutrition, nice taste, simple production, little investment, obvious effect, low cost and wide raw material source. The nanometer SOD fruit wine can lighten the load of the liver, protect liver cell membranes, resist the injury functions of chemical substances, such as ethanol, etc. to liver cells and brain cells, relieve head pain reaction after drinking, eliminate the generation of inflammatory media and inflammatory reaction, and prevent diseases caused by drinking. The efficiency of the nanometer SOD fruit wine is unique, has pertinence, and the nanometer SOD fruit wine is a good product for extensive drinkers.
Description
Affiliated field
The present invention relates to superoxide-dismutase SOD functional food, particularly contain fruit wine of nanometer SOD and preparation method thereof.
Background technology
As everyone knows, the mankind survive on earth and experienced for tensth century, highly developed from elementary diet and primal environment to material progress, earth-shaking variation has taken place in dietary structure, living environment, the picked-up of allegro life, meals and the evolution of environment, all inevitably brought some negative impacts, as radiation, agricultural chemicals, food additive, alcohol, smoking etc., foeign element causes " exogenous oxyradical " on the one hand; On the other hand, in metabolic processes, we are take in oxygen from atmosphere, in lung, carry out chemical reaction with the glucose that behind food digestion, enters in the blood, the energy of our vital movement is kept in generation, in the normal biochemical process, often has the oxygen about 1% to go astray, becoming extremely intensive active oxygen of chemical property, promptly is biochemical reaction produces in the human body " endogenous oxyradical ".The enzyme that participates in various biochemical reactions in the human body is exactly a kind of protein, if the molecular structure of enzyme is attacked because of oxyradical variation has taken place, and will cause the interior vital movement of body to get muddled, and then be infested with all diseases, and directly influences human beings'health and longevity.
Improving environment is social concern, eases off the pressure, reasonable diet is only personal question, how to improve diet, improves disease-resistant, the ability of curing the disease and is the inventor and organizes the problem of research for a long time.Development strategy according to China's food consumption: " being particular about nutrition; guarantee health; pay attention to health care, make every effort to convenient, advocate delicious food, back to nature " and Traditional Chinese medical theory: " doctor's food homology ", worked out the free biology strategy of functional food, both the antioxidant in the diet was used, this be because: the antioxidant in the food can be protected food self, in order to avoid things oxidation damaged and going bad; In human body alimentary canal, have antioxygenation, prevent digestive tube generation oxidative damage; Absorbed antioxidant plays a role at other histoorgans of body; Some antioxidant plant extract or purifying thing can be used as the treatment drug and food, have proposed this new theory of nanometer SOD, and it is widely used in the diet formula, solve and trouble a human health and a long-lived difficult problem for a long time.
Nanometer SOD has utilized new and high technologies such as modern biology and physics, typically refers to handle atom and molecule in 0.1-100 nanometer bulk, and SOD is studied or processes, thus the product innovation that preparation has specific function.When a kind of material constantly is cut to a certain degree, its particle is little to be nano material to nanometer scale, tends to produce some new physicochemical properties.Nanotechnology is applied to the medicine food technical elements, has overcome an insurmountable difficult problem on some conventional medicament food and the technology, provide brand-new approach for promoting medicine food to carry in vivo etc.
Wine and human lives are closely bound up, and in today of human material and spiritual civilization high development, mode of life is particular about high quality, higher-grade, and people have been not content with and have eaten one's fill and worn warm clothes, and wear U.S. but will eat, and wine also becomes the lubricant of these seven color lives undoubtedly.Whenever holidays and observances, kith and kin reunite, usher in and out that guests, wedding dinner are celebrating, the negotiation business opportunity, sign a contract, people cheer invariably and add to the fun, with mood and the ardent friendly atmosphere of expressing cheerful and light-hearted happiness.And in allegro cybertimes, people high efficiency after work also can be with the wine alleviating fatigue, inspire enthusiasm.Therefore, the rich liquor veriety improves the drinks quality, and the demand that satisfies people's consumption also will become the target that wine circle is pursued.All ethanol contents all are called wine or alcoholic beverage above 0.5% beverage and drink.Alcoholic beverage can be divided into fermented wine, liquor and assembled alcoholic drinks.Fermented wine is to use yeast to carry out gained fermented liquid after the zymamsis, and is capable of direct drinking or drink after filtering (comprising yellow rice wine, beer, grape wine and fermentation fruit wine).Why fruit wine is subjected to people's generally hobby, is because it nutritious, and flavour is soft and graceful, fragrance is pleased the people.Sophisticated grape, apple or other fruit, the aroma component of fruit itself are very complicated, the mistake of fruit wine processing and in, the aroma component of fruit itself is along with broken, fermentation, with the form that does not change or seldom change, change in the fruit wine from fresh fruit, just formed the fruital of fruit wine.
Yet wine also has harm: the major ingredient of wine is an alcohol, and chemical name is ethanol, and it enters people's physical efficiency and produces many-sided destruction; Alcohol concn in the blood reaches at 0.05% o'clock, and the effect of alcohol begins to appear, and excitement and floaty euphoria occur; When alcohol concn reached 0.1% in the blood, the people will losing self-control; As reaching at 0.2% o'clock, the people has arrived as drunk as a sow stage; Reach at 0.4% o'clock, the people just can lose consciousness, and remains unconscious, even is in peril of one's life.Alcohol the most important thing is central nervous system to people's infringement, and it makes the inhibition of neural system from excitement to height, seriously destroys neural normal function.Excessive drinking is exactly to damage liver, and chronic alcoholism can cause alcoholic cirrhosis; After drinking, wine is absorbed in gi tract very soon, but only has 2-10% to excrete from kidney and skin, and the ethanol more than 90% will become acetaldehyde by liver cell catalysis at the liver intracellular metabolite.Ethanol and acetaldehyde all have direct stimulation, damage hepatocellular toxic action, can make liver cell that sex change, necrosis take place, even cause serious liver injury, fatty liver and alcoholic cirrhosis.It is generally acknowledged and drink every day more than the 160ml, continuous 5 years, easily cause alcoholic liver disease, will cause liver cirrhosis in continuous 20 years.In the real life, drink above 50ml average every day, and 1 year left and right sides time, alcohol just causes damage to the human liver, and liver cell is in numbness, inert condition, and HUMAN HEALTH and immunizing power descend rapidly.Up-to-date World Health Organization's statistic data shows: the annual hepatopathy that causes because of drinking causes death the number whole world more than 5,000,000, and every year is with 10% speed increase.Chronic alcoholism also has many-sided infringement to health in addition, as causes polyneuritis, myocardium pathology, cerebral lesion, hematopoietic disorder, pancreatitis, gastritis and Peptic Ulcers etc., and the sickness rate of essential hypertension is raise; The somebody notices that long-term heavy drinking can endanger sexual cell, causes offspring's mental retardation; The people's laryngocarcinoma and the digestive tract cancer sickness rate of often drinking obviously increase.So how can drink to one's heart's content and not impair one's health? this is a difficult problem that needs to be resolved hurrily.
Summary of the invention
The present invention be directed to the prior art deficiency, a kind of fruit wine that contains nanometer SOD and preparation method thereof is provided, make it to emphasize that its composition fully shows the body defense function, regulates the industrialization food of physiological rhythm, preventing disease and promotion recovery function people's physical efficiency, satisfy the needs of human health longevity.
The fruit wine that contains nanometer SOD, nanometer SOD 500-2000 activity unit/per kilogram fruit wine.
The fruit wine preparation method who contains nanometer SOD makes the back at fruit wine and adds nanometer SOD 500-2000 activity unit by per kilogram fruit wine, stirs.
We use free radical biology, free radical medical science, traditional Chinese medicine and trophology, adding the extract and the antioxidant vitamins that contain edible plants such as antioxidant nanometer SOD in fruit wine is main recombiner, become nanometer SOD fruit wine, through a series of experiments, prove that it is a kind of novel healthy food efficiently.Its permeability in the human small intestine greatly improves; Rate of release improves; Effect and effective rate of utilization improve greatly, detect data according to contrasting, nearly 10 times of active raising.Nanometer SOD can effectively be broken through the restriction of body biological barrier to the effect of medicine food, makes medicine food enter blood circulation better, lowers and offset the hazardness of wine.The natural biological barrier that human body has many protection bodies to be without prejudice, as hemato encephalic barrier, blood-eye barrier; cell biological envelope barrier etc.; general medicine is difficult to by these body biological barriers, and the nanometer SOD particulate then may pass these barriers, and lesions position is played therapeutic action.
Nanometer SOD has the color spot of removing, chloasma, wrinkle etc. that decisive action is arranged to Ms's skin, can increase the elasticity of skin membrane, prevents aging; The man there is Ginseng Extract, eliminates subhealth state, improves antiviral ability, prevent old and feeble effect, and can reduce prostatitic morbidity risk rate.
Nanometer SOD has overcome influence, the direct absorption difference of outer time spent skin of SOD molecular weight big (greater than 30000), transformation period short (transformation period has only several minutes), oral Digestive system and itself has been a kind of protein has certain immunogenicity, uses weakness such as be very limited.Solved the application limitations and the deficiency of bio proteases such as present SOD, opened new gate, be suitable for penetration and promotion for its widespread use.
Test 1 shows:
(1), hydrochloric acid in gastric juice tolerance result shows that SOD is 37 ℃ of maintenance 150min in mouse simulation hydrochloric acid in gastric juice, vigor still remaining 81%.
(2), Gl tract proteolytic enzyme and pancreatin show that to the enzymolysis result of SOD its vigor of maintenance 210min is remaining under 37 ℃ is respectively 82% and 84%.
(3), the amount of appearing of SOD changes over time after the rat small intestine in vitro ligation, adds the gross activity of small intestine when the gross activity of the outer SOD of small intestine is near test behind the 10h, this shows that SOD can see through small intestine and arrive opposite side from goldbeater's skin one side.
(4), its mouse oral takes in 4h behind the SOD, the SOD activity reaches maximum in the blood, improves 30%%～40% with SOD is active in control group is compared body, therefore oral SOD can obviously improve the SOD level in the blood.
(5), show with the test of fluorescein isothiocyanate (PITC) mark SOD, behind the oral 2h of mouse in the blood marker obviously increase, reach the climax behind the 4h.
Test-results confirms that the SOD of oral uptake can enter in the body.Give mouse stomach with SOD, reach the climax behind the 3h in blood, most of SOD is distributed in the blood plasma, and small portion enters in the hemocyte, and the distribution sequence of SOD in tissue is kidney＞liver＞spleen＞heart.
Test 2 shows: mouse swimming with a load attached to the body test
Group dosage number of animals swimming time P value
(g/kg) (only) X ± S
Negative control group 0 10 88 ± 20.42
SOD organizes 80 10 103 ± 14 0.05
Nanometer SOD group 80 10 148 ± 32 0.001
Experimental result shows, is tried SOD and nanometer SOD group mouse swimming time and negative control group comparison in the thing, and SOD obviously prolongs (P＜0.05), and the average swimming time of nanometer SOD group is significant prolongation (P＜0.001) then.Mouse swimming with a load attached to the body test-results is positive.Two kinds of SOD all have anti-fatigue effect, and the antifatigue effect of nanometer SOD is more obvious.
Conclude the fruit wine of nanometer SOD nothing more than following characteristics: alcoholic strength is low, and is nutritious, delicious; Produce simple, invest little, instant effect, cost is low; Raw material sources are extensive; Can alleviate load of liver, the protection liver plasma membrane, chemical substances such as opposing alcohol are to hepatocellular damaging action; Chemical substances such as opposing alcohol are alleviated brain pain reaction after drinking to the damaging action of brain cell, suppress inflammatory mediator simultaneously again to produce, the inflammation-inhibiting reaction, prevent to cause because of drinking the generation of disease, its effect is unique and targetedly, be undoubtedly the Gospel of numerous alcohol users' health.
Description of drawings
Accompanying drawing 1 of the present invention contains the fruit wine preparation method's of nanometer SOD the process flow sheet of the broken fermentative production fruit flavour type of grape red wine.
Embodiment:
The fruit wine that contains nanometer SOD, nanometer SOD 1500 activity units/per kilogram fruit wine.
The fruit wine preparation method who contains nanometer SOD makes the back at fruit wine and adds nanometer SOD 1500 activity units by per kilogram fruit wine, stirs.
Example 1, contain the fruit wine of nanometer SOD, grape wine, nanometer SOD 500-2000 activity unit/per kilogram grape wine is specially nanometer SOD 1500 activity units/1 kilogram of red wine.
The preparation method: the technical process of the broken fermentative production fruit flavour type of grape red wine is as follows: (seeing accompanying drawing 1)
Example 2, nanometer SOD Hawthorn Fruit Wine, nanometer SOD 20000 activity units/10 kilograms of Hawthorn Fruit Wine.
Preparation method: make the back in Hawthorn Fruit Wine and add nanometer SOD 20000 activity unit's stostes, stir the filling and sealing sterilization by per 10 kilograms.
The nanometer SOD Hawthorn Fruit Wine is to be the wine that raw material leads to fresh mountain scum juice, in hawthorn wine, adds and contains antioxidant nanometer SOD, edible plant extract and antioxidant vitamins, is made into the health care hawthorn wine.Characteristics are not only to keep mountain slag stomach strengthening and digestion promoting, fall food fat, improve nervous function and improve effects such as liver detoxification ability, and are rich in health care active substances such as natural antioxidants, antioxidant vitamins and selenium; Fabulous to prolonging life span of drosophila melanogaster with the tolerance effect that increases anoxia in mice and fatigue; Nanometer SOD is active to be preserved more than 1 year.The experiment proved that this is a kind of functional food of new type of health efficiently.
Example 3, nanometer SOD hard cider, nanometer SOD 50000 activity units/100 kilograms of hard ciders.
The preparation method: the technological process that the nanometer SOD hard cider is brewageed is roughly as follows:
Apple → sorting → washing → fragmentation → pressure juice → ferment → preserve → join 100 kilograms → filtration → adding of wine nanometer SOD, 50000 activity unit's stostes → bottle → pack → dispatch from the factory.Broken general with the broken apple of Universalpulverizer; The general cider fermentation that ferments is all taked spontaneous fermentation, does not promptly add the yeast of artificial culture, finishes fermentation by the wild yeast on the pericarp, and leavening temperature also is a natural temperature, generally about 30 ℃; Preserve general 6 months time, just can join wine and dispatch from the factory; Join the hard cider that wine is sold on the market, ethanol content is about 20% (volume fraction), and pol is about 12%; Add nanometer SOD.
Claims (8)
1. the fruit wine that contains nanometer SOD is characterized in that nanometer SOD 500-2000 activity unit/per kilogram fruit wine.
2. according to the described fruit wine that contains nanometer SOD of claim 1, it is characterized in that nanometer SOD 1500 activity units/per kilogram fruit wine.
3. according to the described fruit wine that contains nanometer SOD of claim 1, it is characterized in that nanometer SOD 1500 activity units/1 kilogram of red wine.
4. according to the described fruit wine that contains nanometer SOD of claim 1, it is characterized in that nanometer SOD 20000 activity units/10 kilograms of Hawthorn Fruit Wine.
5. the fruit wine preparation method of nanometer SOD is characterized in that making the back at fruit wine adds nanometer SOD 500-2000 activity unit by per kilogram fruit wine, stirs.
6. according to the described fruit wine preparation method who contains nanometer SOD of claim 5, it is characterized in that its preparation process is: the grape that sub-elects is carried out the broken grape slurry that gets of destemming; The fermentation of grape slurry separated after 4-6 days, and with residual assorted squeezing the after separating, the squeezing juice after the squeezing mixes with isolating free juice; Mixing juice added oxysuccinic acid after fermenting 3-4 days, carried out lactic fermentation 15 days, and the liquid after the fermentation carries out also bucket, bucket, storage; Stock solution is filtered by diatomite; Carry out clarification filtration and Sterile Filtration after the filtrate that obtains is freezing successively; With after adding nanometer SOD in the gained filtrate, carry out sterile filling afterwards.
7. according to the described fruit wine preparation method who contains nanometer SOD of claim 5, it is characterized in that making the back in Hawthorn Fruit Wine adds nanometer SOD 20000 activity unit's stostes by per 10 kilograms, stirs the filling and sealing sterilization.
8. according to the described fruit wine preparation method who contains nanometer SOD of claim 5, it is characterized in that its preparation process is: the apple that sub-elects is clean, broken, squeeze into juice; Squeezing juice spontaneous fermentation storage was joined 100 kilograms of wine after 6 months; Mixed fruit wine is filtered, add nanometer SOD 50000 activity unit's stostes; The gained finished product is bottled, packs, is dispatched from the factory.
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| CNB2004100209901A CN100392058C (en) | 2004-07-19 | 2004-07-19 | Fruit wine containing nano-SOD and its preparation method |
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| CN100392058C true CN100392058C (en) | 2008-06-04 |
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Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103451061A (en) * | 2013-08-29 | 2013-12-18 | 成都磊淼商贸有限公司 | Process for adding superoxide dismutase (SOD) in fruit wine making |
| CN104312812A (en) * | 2014-09-25 | 2015-01-28 | 安徽圣堡利诺葡萄酒庄园有限公司 | Grape wine with function of invigorating qi and blood and preparation method of grape wine |
| CN104312817A (en) * | 2014-09-25 | 2015-01-28 | 安徽圣堡利诺葡萄酒庄园有限公司 | Wine with functions of nourishing brain and improving intelligence and preparation method thereof |
| CN104312816A (en) * | 2014-09-25 | 2015-01-28 | 安徽圣堡利诺葡萄酒庄园有限公司 | Wine with life prolonging function and preparation method thereof |
| CN105936848A (en) * | 2015-03-23 | 2016-09-14 | 孙燕霞 | Preparation method of SOD wine |
| CN104673578B (en) * | 2015-03-23 | 2016-09-14 | 青岛橡胶谷知识产权有限公司 | There is SOD wine and the preparation method of health-care effect |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1156174A (en) * | 1996-01-29 | 1997-08-06 | 成都市龙泉生物酒厂 | Weierkang enzymatic (SOD) wine and its producing method |
| CN1045371C (en) * | 1994-05-27 | 1999-10-06 | 张进 | Nourishing liquor of Arctostaphylos Uva-ursi Spreng and preparation method thereof |
| CN1061087C (en) * | 1996-07-16 | 2001-01-24 | 刘凤英 | Strawberry wine and its making process |
| CN1327044A (en) * | 2001-06-04 | 2001-12-19 | 高瑞伦 | Process for producing dismutase wine |
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- 2004-07-19 CN CNB2004100209901A patent/CN100392058C/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1045371C (en) * | 1994-05-27 | 1999-10-06 | 张进 | Nourishing liquor of Arctostaphylos Uva-ursi Spreng and preparation method thereof |
| CN1156174A (en) * | 1996-01-29 | 1997-08-06 | 成都市龙泉生物酒厂 | Weierkang enzymatic (SOD) wine and its producing method |
| CN1061087C (en) * | 1996-07-16 | 2001-01-24 | 刘凤英 | Strawberry wine and its making process |
| CN1327044A (en) * | 2001-06-04 | 2001-12-19 | 高瑞伦 | Process for producing dismutase wine |
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