CN100369603C - Product recipe for bee glue soft capsule inclusion - Google Patents

Product recipe for bee glue soft capsule inclusion Download PDF

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Publication number
CN100369603C
CN100369603C CNB2005100605556A CN200510060555A CN100369603C CN 100369603 C CN100369603 C CN 100369603C CN B2005100605556 A CNB2005100605556 A CN B2005100605556A CN 200510060555 A CN200510060555 A CN 200510060555A CN 100369603 C CN100369603 C CN 100369603C
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China
Prior art keywords
soft capsule
product
propolis
fatty acid
kilograms
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Expired - Fee Related
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CNB2005100605556A
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Chinese (zh)
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CN1748716A (en
Inventor
钱志明
周平
孙建芳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hangzhou Beewords Bee Industry Co., Ltd.
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ZHEJIANG BEE WORDS BEE INDUSTRY GROUP Co Ltd
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Priority to CNB2005100605556A priority Critical patent/CN100369603C/en
Publication of CN1748716A publication Critical patent/CN1748716A/en
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Publication of CN100369603C publication Critical patent/CN100369603C/en
Expired - Fee Related legal-status Critical Current
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  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Jellies, Jams, And Syrups (AREA)

Abstract

The present invention relates to a product formula for a propolis soft capsule inclusion. The formula comprises propolis, polyglyceryl fatty acid ester, caprylin and caprin. The present invention has the advantages of stable product property, homogeneous dispersion in water and good biological availability. The product does not use polyethyleneglycol and vegetable oil so that the defect caused by using the polyethyleneglycol and the vegetable oil is overcome. The health care functions of the caprylin and the caprin are enhanced and the health care effect of the product is enhanced. The shelf life of the product is extended by an antibacterial function of the ingredients in the product of the present invention.

Description

A kind of bee glue soft capsule content
Technical field
The present invention relates to a kind of bee glue soft capsule content, be mainly used in the making of making propolis class health product, especially bee glue soft capsule.
Background technology
Existing bee glue soft capsule, prescription mainly contains three kinds: a kind of be with vegetable oil with after propolis mixes, by emulsifying agents such as monoglyceride, tween, Cera Flavas,, and then carry out the filling of soft capsule by the colloid mill mix homogeneously.The production time of this series products the earliest, but with the vegetable oil is the soft capsule of batching, because propolis is not dissolved in the vegetable oil fully, the poor stability of product, in the storage process, oil separates with propolis, influences absorption of human body, unsaturated fatty acid in the vegetable oil is long time stored in addition can oxidative rancidity, influences the quality of product.Second kind of product is main batching with the Polyethylene Glycol, it is dissolved with propolis, be aided with other emulsifying agents or cosolvent again, do not need by colloid mill, form the propolis liquid of homogeneous, recharge into soft capsule, this series products sees 2000 the earliest, is the bee glue soft capsule of adjuvant with the Polyethylene Glycol, and the Polyethylene Glycol water absorption is strong, can cause capsule shells dehydration sclerosis, content leaks, and is unfavorable for long term store, and Polyethylene Glycol is under the oxygen existence condition, can produce the formaldehydes material, influence the disintegration of quality and softgel shell.Polyethylene Glycol still excludes in " food additive use sanitary standard ", just as pharmaceutic adjuvant, it is used for health food or food still can't be advised support.The third product is to occur recently, and it has the characteristic of above-mentioned first two product concurrently,, earlier propolis is dissolved in Polyethylene Glycol that is, again with this solution and vegetable oil by emulsifying agent emulsifying, recharge soft capsule, also have the shortcoming of above-mentioned first two product simultaneously.
Summary of the invention
Technical problem to be solved by this invention provides reasonable, the easy absorption of a kind of recipe design, difficult corruption, stable in properties, is convenient to the prescription of the bee glue soft capsule content of long term storage.
The present invention solves the problems of the technologies described above the prescription that the technical scheme that is adopted is this bee glue soft capsule content, is characterized in: filling a prescription is: propolis, polyglyceryl fatty acid ester and decanoyl/octanoyl glycerides.
The quality percentage composition of propolis of the present invention, polyglyceryl fatty acid ester and decanoyl/octanoyl glycerides is: propolis: 10%-40%; Polyglyceryl fatty acid ester: 10-40%; Decanoyl/octanoyl glycerides: 20%-60%.
The present invention compares with prior art and has the following advantages and effect: 1, product property of the present invention is stable, homodisperse in water, and bioavailability is good; 2, product of the present invention does not use Polyethylene Glycol and vegetable oil, has overcome the deficiency because of using both to bring; 3, in the product of the present invention, the health-care effect of decanoyl/octanoyl glycerides itself strengthens and has increased the health-care effect of product; The antibacterial action of preparing burden in the product of the present invention has prolonged the shelf-life of product.
The specific embodiment
The present invention is described in further detail below in conjunction with embodiment, and following examples are explanation of the invention and the present invention is not limited to following examples.
Embodiment 1:
By the raw materials quality standard-required raw material is carried out an acceptance inspection, take by weighing 10 kilograms of propolis then; 50 kilograms of decanoyl/octanoyl glycerides; 40 kilograms of polyglyceryl fatty acid esters, decanoyl/octanoyl glycerides and polyglyceryl fatty acid ester are dropped in the dissolving tank, heat and mix in 75 ℃ of-85 ℃ of following water-baths, after reaching the requirement temperature, adding propolis dissolves while stirring, liquid when mixed liquor formation homogeneous can be dispersed in the water uniformly, and it is qualified promptly to dissolve.Above-mentioned solute continues to stir 0.5-1h, reaches the homogenizing purpose.Material is cooled to 50 ℃ then, discharging, carrying out soft capsule by the general production technology of soft capsule fills, populated soft capsule is finalized the design in rotating cage, with vestiges such as edible ethanol flush away greasy dirts, dry 16-30h in drying shed then chooses special-shaped ball, flat ball in the soft capsule that drying finishes again, leaks ball grade ball, packs at last.
Embodiment 2:
By the raw materials quality standard-required raw material is carried out an acceptance inspection, take by weighing 25 kilograms of propolis then; 40 kilograms of decanoyl/octanoyl glycerides; 35 kilograms of polyglyceryl fatty acid esters, decanoyl/octanoyl glycerides and polyglyceryl fatty acid ester are dropped in the dissolving tank, heat and mix in 75 ℃ of-85 ℃ of following water-baths, after reaching the requirement temperature, adding propolis dissolves while stirring, liquid when mixed liquor formation homogeneous can be dispersed in the water uniformly, and it is qualified promptly to dissolve.Above-mentioned solute continues to stir 0.5-1h, reaches the homogenizing purpose.Material is cooled to 50 ℃ then, discharging, carrying out soft capsule by the general production technology of soft capsule fills, populated soft capsule is finalized the design in rotating cage, with vestiges such as edible ethanol flush away greasy dirts, dry 16-30h in drying shed then chooses special-shaped ball, flat ball in the soft capsule that drying finishes again, leaks ball grade ball, packs at last.
Embodiment 3:
By the raw materials quality standard-required raw material is carried out an acceptance inspection, take by weighing 35 kilograms of propolis then; 45 kilograms of decanoyl/octanoyl glycerides; 20 kilograms of polyglyceryl fatty acid esters, decanoyl/octanoyl glycerides and polyglyceryl fatty acid ester are dropped in the dissolving tank, heat and mix in 75 ℃ of-85 ℃ of following water-baths, after reaching the requirement temperature, adding propolis dissolves while stirring, liquid when mixed liquor formation homogeneous can be dispersed in the water uniformly, and it is qualified promptly to dissolve.Above-mentioned solute continues to stir 0.5-1h, reaches the homogenizing purpose.Material is cooled to 50 ℃ then, discharging, carrying out soft capsule by the general production technology of soft capsule fills, populated soft capsule is finalized the design in rotating cage, with vestiges such as edible ethanol flush away greasy dirts, dry 16-30h in drying shed then chooses special-shaped ball, flat ball in the soft capsule that drying finishes again, leaks ball grade ball, packs at last.
Embodiment 4:
By the raw materials quality standard-required raw material is carried out an acceptance inspection, take by weighing 40 kilograms of propolis then; 20 kilograms of decanoyl/octanoyl glycerides; 40 kilograms of polyglyceryl fatty acid esters, decanoyl/octanoyl glycerides and polyglyceryl fatty acid ester are dropped in the dissolving tank, heat and mix in 75 ℃ of-85 ℃ of following water-baths, after reaching the requirement temperature, adding propolis dissolves while stirring, liquid when mixed liquor formation homogeneous can be dispersed in the water uniformly, and it is qualified promptly to dissolve.Above-mentioned solute continues to stir 0.5-1h, reaches the homogenizing purpose.Material is cooled to 50 ℃ then, discharging, carrying out soft capsule by the general production technology of soft capsule fills, populated soft capsule is finalized the design in rotating cage, with vestiges such as edible ethanol flush away greasy dirts, dry 16-30h in drying shed then chooses special-shaped ball, flat ball in the soft capsule that drying finishes again, leaks ball grade ball, packs at last.
Embodiment 5:
By the raw materials quality standard-required raw material is carried out an acceptance inspection, take by weighing 20 kilograms of propolis then; 60 kilograms of decanoyl/octanoyl glycerides; 20 kilograms of polyglyceryl fatty acid esters, decanoyl/octanoyl glycerides and polyglyceryl fatty acid ester are dropped in the dissolving tank, heat and mix in 75 ℃ of-85 ℃ of following water-baths, after reaching the requirement temperature, adding propolis dissolves while stirring, liquid when mixed liquor formation homogeneous can be dispersed in the water uniformly, and it is qualified promptly to dissolve.Above-mentioned solute continues to stir 0.5-1h, reaches the homogenizing purpose.Material is cooled to 50 ℃ then, discharging, carrying out soft capsule by the general production technology of soft capsule fills, populated soft capsule is finalized the design in rotating cage, with vestiges such as edible ethanol flush away greasy dirts, dry 16-30h in drying shed then chooses special-shaped ball, flat ball in the soft capsule that drying finishes again, leaks ball grade ball, packs at last.
Embodiment 6:
By the raw materials quality standard-required raw material is carried out an acceptance inspection, take by weighing 35 kilograms of propolis then; 55 kilograms of decanoyl/octanoyl glycerides; 10 kilograms of polyglyceryl fatty acid esters, decanoyl/octanoyl glycerides and polyglyceryl fatty acid ester are dropped in the dissolving tank, heat and mix in 75 ℃ of-85 ℃ of following water-baths, after reaching the requirement temperature, adding propolis dissolves while stirring, liquid when mixed liquor formation homogeneous can be dispersed in the water uniformly, and it is qualified promptly to dissolve.Above-mentioned solute continues to stir 0.5-1h, reaches the homogenizing purpose.Material is cooled to 50 ℃ then, discharging, carrying out soft capsule by the general production technology of soft capsule fills, populated soft capsule is finalized the design in rotating cage, with vestiges such as edible ethanol flush away greasy dirts, dry 16-30h in drying shed then chooses special-shaped ball, flat ball in the soft capsule that drying finishes again, leaks ball grade ball, packs at last.

Claims (1)

1. bee glue soft capsule content is characterized in that: prescription and quality percentage composition are: propolis: 10%-40%; Polyglyceryl fatty acid ester: 10-40%; Decanoyl/octanoyl glycerides: 20%-60%.
CNB2005100605556A 2005-08-30 2005-08-30 Product recipe for bee glue soft capsule inclusion Expired - Fee Related CN100369603C (en)

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Application Number Priority Date Filing Date Title
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CN100369603C true CN100369603C (en) 2008-02-20

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Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1965813B (en) * 2006-08-24 2010-05-12 王超敏 Compound soft capsule of propolis
CN101878870A (en) * 2010-06-22 2010-11-10 江西汪氏蜜蜂园有限公司 Preparation method of propolis all-components soft capsule
CN102133237A (en) * 2011-03-31 2011-07-27 射阳县庆缘康蜂产品厂 Propolis flavone soft capsule and preparation method thereof
CN102499338B (en) * 2011-12-31 2013-07-03 杭州蜂之语蜂业股份有限公司 Hydrophilic propolis powder capsule composition and production method thereof
CN103005250B (en) * 2012-12-10 2014-04-16 杭州蜂之语蜂业股份有限公司 Preparation process of propolis solution

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1323586A (en) * 2000-05-12 2001-11-28 中国农业科学院蜜蜂研究所 Formulation and production process of bee glue capsule
CN1460487A (en) * 2003-06-08 2003-12-10 刘进祖 Propolis soft capsule and its preparation method
CN1555812A (en) * 2004-01-12 2004-12-22 北京正大绿洲医药科技有限公司 Propolis drip pill and its preparation method
CN1568760A (en) * 2004-05-11 2005-01-26 浙江蜂之语蜂业集团有限公司 Propolis soft capsule

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1323586A (en) * 2000-05-12 2001-11-28 中国农业科学院蜜蜂研究所 Formulation and production process of bee glue capsule
CN1460487A (en) * 2003-06-08 2003-12-10 刘进祖 Propolis soft capsule and its preparation method
CN1555812A (en) * 2004-01-12 2004-12-22 北京正大绿洲医药科技有限公司 Propolis drip pill and its preparation method
CN1568760A (en) * 2004-05-11 2005-01-26 浙江蜂之语蜂业集团有限公司 Propolis soft capsule

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Owner name: HANGZHOU WORDS BEE APICULTURE CO.,LTD.

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Address after: The streets of Zhejiang province Tonglu County Road No. 898 Tong Jun Joe

Patentee after: Hangzhou Beewords Bee Industry Co., Ltd.

Address before: The streets of Zhejiang province Tonglu County Road No. 898 Tong Jun Joe

Patentee before: Zhejiang Bee Words Bee Industry Group Co., Ltd.

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