Background technology
Existing bee glue soft capsule, prescription mainly contains three kinds: a kind of be with vegetable oil with after propolis mixes, by emulsifying agents such as monoglyceride, tween, Cera Flavas,, and then carry out the filling of soft capsule by the colloid mill mix homogeneously.The production time of this series products the earliest, but with the vegetable oil is the soft capsule of batching, because propolis is not dissolved in the vegetable oil fully, the poor stability of product, in the storage process, oil separates with propolis, influences absorption of human body, unsaturated fatty acid in the vegetable oil is long time stored in addition can oxidative rancidity, influences the quality of product.Second kind of product is main batching with the Polyethylene Glycol, it is dissolved with propolis, be aided with other emulsifying agents or cosolvent again, do not need by colloid mill, form the propolis liquid of homogeneous, recharge into soft capsule, this series products sees 2000 the earliest, is the bee glue soft capsule of adjuvant with the Polyethylene Glycol, and the Polyethylene Glycol water absorption is strong, can cause capsule shells dehydration sclerosis, content leaks, and is unfavorable for long term store, and Polyethylene Glycol is under the oxygen existence condition, can produce the formaldehydes material, influence the disintegration of quality and softgel shell.Polyethylene Glycol still excludes in " food additive use sanitary standard ", just as pharmaceutic adjuvant, it is used for health food or food still can't be advised support.The third product is to occur recently, and it has the characteristic of above-mentioned first two product concurrently,, earlier propolis is dissolved in Polyethylene Glycol that is, again with this solution and vegetable oil by emulsifying agent emulsifying, recharge soft capsule, also have the shortcoming of above-mentioned first two product simultaneously.
Summary of the invention
Technical problem to be solved by this invention provides reasonable, the easy absorption of a kind of recipe design, difficult corruption, stable in properties, is convenient to the prescription of the bee glue soft capsule content of long term storage.
The present invention solves the problems of the technologies described above the prescription that the technical scheme that is adopted is this bee glue soft capsule content, is characterized in: filling a prescription is: propolis, polyglyceryl fatty acid ester and decanoyl/octanoyl glycerides.
The quality percentage composition of propolis of the present invention, polyglyceryl fatty acid ester and decanoyl/octanoyl glycerides is: propolis: 10%-40%; Polyglyceryl fatty acid ester: 10-40%; Decanoyl/octanoyl glycerides: 20%-60%.
The present invention compares with prior art and has the following advantages and effect: 1, product property of the present invention is stable, homodisperse in water, and bioavailability is good; 2, product of the present invention does not use Polyethylene Glycol and vegetable oil, has overcome the deficiency because of using both to bring; 3, in the product of the present invention, the health-care effect of decanoyl/octanoyl glycerides itself strengthens and has increased the health-care effect of product; The antibacterial action of preparing burden in the product of the present invention has prolonged the shelf-life of product.
The specific embodiment
The present invention is described in further detail below in conjunction with embodiment, and following examples are explanation of the invention and the present invention is not limited to following examples.
Embodiment 1:
By the raw materials quality standard-required raw material is carried out an acceptance inspection, take by weighing 10 kilograms of propolis then; 50 kilograms of decanoyl/octanoyl glycerides; 40 kilograms of polyglyceryl fatty acid esters, decanoyl/octanoyl glycerides and polyglyceryl fatty acid ester are dropped in the dissolving tank, heat and mix in 75 ℃ of-85 ℃ of following water-baths, after reaching the requirement temperature, adding propolis dissolves while stirring, liquid when mixed liquor formation homogeneous can be dispersed in the water uniformly, and it is qualified promptly to dissolve.Above-mentioned solute continues to stir 0.5-1h, reaches the homogenizing purpose.Material is cooled to 50 ℃ then, discharging, carrying out soft capsule by the general production technology of soft capsule fills, populated soft capsule is finalized the design in rotating cage, with vestiges such as edible ethanol flush away greasy dirts, dry 16-30h in drying shed then chooses special-shaped ball, flat ball in the soft capsule that drying finishes again, leaks ball grade ball, packs at last.
Embodiment 2:
By the raw materials quality standard-required raw material is carried out an acceptance inspection, take by weighing 25 kilograms of propolis then; 40 kilograms of decanoyl/octanoyl glycerides; 35 kilograms of polyglyceryl fatty acid esters, decanoyl/octanoyl glycerides and polyglyceryl fatty acid ester are dropped in the dissolving tank, heat and mix in 75 ℃ of-85 ℃ of following water-baths, after reaching the requirement temperature, adding propolis dissolves while stirring, liquid when mixed liquor formation homogeneous can be dispersed in the water uniformly, and it is qualified promptly to dissolve.Above-mentioned solute continues to stir 0.5-1h, reaches the homogenizing purpose.Material is cooled to 50 ℃ then, discharging, carrying out soft capsule by the general production technology of soft capsule fills, populated soft capsule is finalized the design in rotating cage, with vestiges such as edible ethanol flush away greasy dirts, dry 16-30h in drying shed then chooses special-shaped ball, flat ball in the soft capsule that drying finishes again, leaks ball grade ball, packs at last.
Embodiment 3:
By the raw materials quality standard-required raw material is carried out an acceptance inspection, take by weighing 35 kilograms of propolis then; 45 kilograms of decanoyl/octanoyl glycerides; 20 kilograms of polyglyceryl fatty acid esters, decanoyl/octanoyl glycerides and polyglyceryl fatty acid ester are dropped in the dissolving tank, heat and mix in 75 ℃ of-85 ℃ of following water-baths, after reaching the requirement temperature, adding propolis dissolves while stirring, liquid when mixed liquor formation homogeneous can be dispersed in the water uniformly, and it is qualified promptly to dissolve.Above-mentioned solute continues to stir 0.5-1h, reaches the homogenizing purpose.Material is cooled to 50 ℃ then, discharging, carrying out soft capsule by the general production technology of soft capsule fills, populated soft capsule is finalized the design in rotating cage, with vestiges such as edible ethanol flush away greasy dirts, dry 16-30h in drying shed then chooses special-shaped ball, flat ball in the soft capsule that drying finishes again, leaks ball grade ball, packs at last.
Embodiment 4:
By the raw materials quality standard-required raw material is carried out an acceptance inspection, take by weighing 40 kilograms of propolis then; 20 kilograms of decanoyl/octanoyl glycerides; 40 kilograms of polyglyceryl fatty acid esters, decanoyl/octanoyl glycerides and polyglyceryl fatty acid ester are dropped in the dissolving tank, heat and mix in 75 ℃ of-85 ℃ of following water-baths, after reaching the requirement temperature, adding propolis dissolves while stirring, liquid when mixed liquor formation homogeneous can be dispersed in the water uniformly, and it is qualified promptly to dissolve.Above-mentioned solute continues to stir 0.5-1h, reaches the homogenizing purpose.Material is cooled to 50 ℃ then, discharging, carrying out soft capsule by the general production technology of soft capsule fills, populated soft capsule is finalized the design in rotating cage, with vestiges such as edible ethanol flush away greasy dirts, dry 16-30h in drying shed then chooses special-shaped ball, flat ball in the soft capsule that drying finishes again, leaks ball grade ball, packs at last.
Embodiment 5:
By the raw materials quality standard-required raw material is carried out an acceptance inspection, take by weighing 20 kilograms of propolis then; 60 kilograms of decanoyl/octanoyl glycerides; 20 kilograms of polyglyceryl fatty acid esters, decanoyl/octanoyl glycerides and polyglyceryl fatty acid ester are dropped in the dissolving tank, heat and mix in 75 ℃ of-85 ℃ of following water-baths, after reaching the requirement temperature, adding propolis dissolves while stirring, liquid when mixed liquor formation homogeneous can be dispersed in the water uniformly, and it is qualified promptly to dissolve.Above-mentioned solute continues to stir 0.5-1h, reaches the homogenizing purpose.Material is cooled to 50 ℃ then, discharging, carrying out soft capsule by the general production technology of soft capsule fills, populated soft capsule is finalized the design in rotating cage, with vestiges such as edible ethanol flush away greasy dirts, dry 16-30h in drying shed then chooses special-shaped ball, flat ball in the soft capsule that drying finishes again, leaks ball grade ball, packs at last.
Embodiment 6:
By the raw materials quality standard-required raw material is carried out an acceptance inspection, take by weighing 35 kilograms of propolis then; 55 kilograms of decanoyl/octanoyl glycerides; 10 kilograms of polyglyceryl fatty acid esters, decanoyl/octanoyl glycerides and polyglyceryl fatty acid ester are dropped in the dissolving tank, heat and mix in 75 ℃ of-85 ℃ of following water-baths, after reaching the requirement temperature, adding propolis dissolves while stirring, liquid when mixed liquor formation homogeneous can be dispersed in the water uniformly, and it is qualified promptly to dissolve.Above-mentioned solute continues to stir 0.5-1h, reaches the homogenizing purpose.Material is cooled to 50 ℃ then, discharging, carrying out soft capsule by the general production technology of soft capsule fills, populated soft capsule is finalized the design in rotating cage, with vestiges such as edible ethanol flush away greasy dirts, dry 16-30h in drying shed then chooses special-shaped ball, flat ball in the soft capsule that drying finishes again, leaks ball grade ball, packs at last.