CN100352482C - Medicine for treating burn and scald - Google Patents

Abstract

The present invention discloses a medicine for treating burns and scalds, which is prepared from alkanna tinctoria, bletilla tuber, rhubarb, rice bran, sanguisorba roots, crinis carbonisatus, borneol and sesame oil which are used as raw materials by crushing, mixing, decocting, filtering, deslagging and grease collecting. The present invention can be used for wide indications and has obvious treatment effects on various burns, scalds and chemical burns; wound surfaces are obviously cured from interior to exterior after the medicine is used; in addition, the present invention has the advantages of rapid pain alleviation and heat clearing for detumescence, no scars after cure, rapid effects, stable curative effects and each acceptance for patients; scores of years of clinical observations and treatment in a long term prove that the curative effects are outstanding and the effects are rapid, and allergic reaction or toxic and side effects can not occur; the functions of alleviating pain and relieving itching can be performed for patients with slight level 2 burns and scalds after the medicine is used for 30 minutes to 2 hours; patients can be generally cured within 5 to 7 weeks, the effectiveness ratio can reach 88%, and the curative ratio can reach 71%.

Description

A kind of medicine for the treatment of burn and scald

Technical field

The present invention relates to treat the pharmaceutical composition of burn and scald, particularly relating to a kind of is the medicine of the treatment burn and scald made of raw material with the Chinese herbal medicine.

Background technology

The tradition traditional Chinese medical science is being cured existing history in several thousand on the burn and scald, Therapeutic Method is also more, as adopt unguentum that Chinese herbal medicine makes, powder, water preparation etc., wherein as treatment burn-scald medicines such as Adeps melis, JINGWANHONG, cream-coloured cream, though have necessarily or curative effect preferably, exist that treatment cycle is long, analgesia heat clearing away poor effect, patient suffering are big, leave drawback such as obvious cicatrix after more.

Goal of the invention

The present invention aims to provide the Chinese herbal medicine of a kind of short treating period, the pain relieving heat clearing away effect treatment burn and scald that significantly, more the back cicatrix is little.

Summary of the invention

For realizing purpose of the present invention, medicine of the present invention is formulated by the crude drug of following portions by weight ratio:

Radix Arnebiae (Radix Lithospermi) 8～15 Pseudobulbus Bletillae (Rhizoma Bletillae)s 8～15 Radix Et Rhizoma Rhei 10～20

Surplus Plantula Papaveris 4～10 Radix Sanguisorbaes 6～15 2～4

Borneolum Syntheticum 0.03～0.1 Oleum sesami 300～500.

Medicine preferred weight umber ratio range of the present invention is:

Radix Arnebiae (Radix Lithospermi) 10～12 Pseudobulbus Bletillae (Rhizoma Bletillae)s 10～12 Radix Et Rhizoma Rhei 12～16

Plantula Papaveris 6～8 Radix Sanguisorbaes 8～12 Crinis Carbonisatus 2～4

Borneolum Syntheticum 0.05～0.08 Oleum sesami 350～450.

Medicine optimum weight umber proportioning of the present invention is:

Radix Arnebiae (Radix Lithospermi) 10 Pseudobulbus Bletillae (Rhizoma Bletillae)s 10 Radix Et Rhizoma Rhei 15

Plantula Papaveris 7 Radix Sanguisorbaes 10 Crinis Carbonisatus 3

Borneolum Syntheticum 0.06 Oleum sesami 400.

Preparation method of the present invention is:

A. at first will cleaning also, dried Radix Arnebiae (Radix Lithospermi), the Pseudobulbus Bletillae (Rhizoma Bletillae), Crinis Carbonisatus, Radix Et Rhizoma Rhei, Plantula Papaveris, Radix Sanguisorbae grind to 80～100 orders standby respectively;

B. grind Borneolum Syntheticum standby to 80～100 orders;

C. take by weighing each component that a step makes respectively by above-mentioned ratio of weight and number, and it is fully mixed;

D. the mixture that the c step is made adds in the hot Oleum sesami of required part by weight, stir and endure to crude drug mixture surface to filter when sallow and abandon medicinal residues, treat to add when temperature is reduced to 50～70 ℃ the Borneolum Syntheticum of required grinding, fully stir, receive cream, promptly make the medicine of treatment burn and scald of the present invention.Also available other vegetable oil of above-mentioned Oleum sesami replaces, as Oleum Arachidis hypogaeae semen, Semen Allii Tuberosi wet goods, but preferred Oleum sesami.

The effect of each component of the present invention is respectively:

Radix Arnebiae (Radix Lithospermi): the nature and flavor hardship, salty-cold, have the effect that clearing away heat and cooling blood, cooling blood for hemostasis, reducing swelling and alleviating pain, granulation promoting are put on flesh; The Pseudobulbus Bletillae (Rhizoma Bletillae): the nature and flavor hardship, sweet wet, be slightly cold, have the effect of astringing to arrest bleeding, detumescence and promoting granulation, cooling blood and relieving pain; Radix Et Rhizoma Rhei: the nature and flavor bitter cold has the effect of removing heat from blood removing heat from blood, blood circulation promoting and blood stasis dispelling, clearing heat for detumescence; Crinis Carbonisatus (Crinis Carbonisatus): nature and flavor are bitter flat, according to the Tang Materia Medica record, can be used for treating not closing up for a long time after skin infection is burst and wait disease, make that new meat is given birth to, the open sore part is closed, and have the effect of stop blooding dissipating blood stasis, promoting tissue regeneration by astringents; Radix Sanguisorbae: the nature and flavor picric acid is cold, has cooling blood for hemostasis, detoxifies and hold back the effect of skin ulcer; Pericarpium Papaveris: nature and flavor acid is flat, has hemostasis, pain relieving effect; Borneolum Syntheticum: nature and flavor suffering, hardship, cold, according to " Bencao Jingshu " record, Borneolum Syntheticum " all rheumatism of loosing are so main trusted subordinate's pathogen and rheumatism are gathered also ", have the refreshment of having one's ideas straightened out, heat clearing away loose swollen, pain relieving, granulation promoting effect, diseases such as the various skin infection of external curing, laryngopharynx swelling and pain, aphtha, order disease.Oleum sesami: the sweet cold of nature and flavor has the effect of moistening dryness for relaxing bowels, removing toxic substances and promoting granulation.

In addition from the chemical analysis analysis as can be known the drug effect of above-mentioned each crude drug be respectively:

That Radix Arnebiae (Radix Lithospermi) has is analgesic, antiviral, antibacterial and cardiotonic;

The Pseudobulbus Bletillae (Rhizoma Bletillae) has anastalsis;

Radix Et Rhizoma Rhei has and rushes down following, antibiotic, hemostasis and choleretic effect;

Plantula Papaveris has analgesic activity;

Radix Sanguisorbae has hemostasis, antibacterial action;

Crinis Carbonisatus has antibiotic, Blood clotting;

Borneolum Syntheticum has pain relieving, anticorrosion, antibacterial action.

The inventor based on cooling blood for hemostasis, heat-clearing and toxic substances removing, expelling pus and promoting granulation, is auxilliary invention this medicine with the convergence analgesia by to the research of burn and scald mechanism, pathology and the Chinese herbal medicine property of medicine and long-term for many years clinical practice experience.In the present invention, be monarch with Radix Arnebiae (Radix Lithospermi), Radix Sanguisorbae, Crinis Carbonisatus, but minister can reach the effect of holding back skin ulcer, heat-clearing and toxic substances removing with the Pseudobulbus Bletillae (Rhizoma Bletillae) of expelling pus and promoting granulation with cooling blood for hemostasis, detoxifcation heat clearing away, assistant is with the Borneolum Syntheticum refreshment of can having one's ideas straightened out, and makes to have the Plantula Papaveris of pain relieving effect.Behind the above-mentioned medicine compatibility of respectively distinguishing the flavor of the effect of clearing heat for detumescence, promoting blood circulation and cooling blood, antalgesic-antipruritic is further strengthened.

Clinical drug of the present invention uses the result to show to have remarkable characteristic and effect in following several respects:

1. owing to adopt Radix Arnebiae (Radix Lithospermi), the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Et Rhizoma Rhei, Plantula Papaveris, Radix Sanguisorbae, Crinis Carbonisatus, Borneolum Syntheticum compatibility, make that medicine indication of the present invention is wide, all kinds of burns, scald, chemical burn had notable therapeutic effect, wound surface obviously from inside to outside takes a turn for the better rapidly after the medication, and pain relieving, clearing heat for detumescence are fast, and more no cicatrix in back or cicatrix are little, and effect is rapid, stable curative effect, the patient is easy to accept.

2. prove through long-term clinical observation decades and treatment, determined curative effect of the present invention, produce effects is fast, does not have any anaphylaxis and toxic and side effects.

3. behind use the present invention visible positive effect, to can reaching antalgesic-antipruritic in 30 minutes to 2 hours after the shallow II degree burn and scald patient medication, and short treating period, general 5～7 weeks recovery from illness of patient, effective percentage reaches more than 88%, and cure rate reaches 71%.

For showing the therapeutic effect of herbal mediciment of the present invention to burn and scald, the present invention selects burn and scald patient 100 examples to be the clinical observation object.Concrete condition is as follows:

Wherein: male 87 people, women 13 people, I degree burn and scald patient 53 examples wherein, II degree burn and scald patient 47 examples.5～68 years old age, 9 examples of person below 30 years old wherein, 31～40 years old 48 example, 41～68 years old 43 example.

Using method: 2～3 times/day, evenly smear the affected part, recovery from illness in general 5～7 weeks.

By clinical observation and treatment, relevant therapeutic effect sees the following form.

The therapeutic effect synopsis

Criterion of therapeutical effect wherein:

Produce effects: medication pain relief on the same day or disappearance, redness alleviated in 6 days.

Effectively: medication after 3 days redness alleviate, red and swollen face diminishes, or 3～7 all healing persons.

Cure: the red and swollen disappearance.

Invalid: no significant change before and after the treatment.

Pharmacological action of the present invention can change symptom rapidly, promotes organized renewing, has cooling blood for hemostasis, heat-clearing and toxic substances removing, expelling pus and promoting granulation, and the convergence analgesia waits effect.Can in 1～2 week, produce obviously effect to I degree, II degree burn and scald, can recovery from illness in 3～7 weeks.

The present invention is as follows at some model cases of clinical practice:

Case 1: Wang Xiuyun, the woman, 35 years old, people from Wuyi County, Hebei province, patient main suit's boiled water scalds its left lower limb 30 centimeters places at one's knees, once uses JINGWANHONG 3 days, poor effect, on November 20th, 2003 examined.Through looking into patient's limitation of activity, the red and swollen causalgia in edge, affected part, the mucocutaneous destruction of wound surface, belong to the II degree and scald, advise that this patient uses the present invention, through be coated with after 4 hours, scorching hot pain relief, aforementioned transference cure after 3 days, scald place, 3 week back takes a favorable turn, the back recovery from illness of 2 week of reuse.

Case 2: wish pleasure, man, 10 years old, people from Wuyi County, Hebei province, because of careless boiled water scalds its left foot, December was examined on the 16th in 2004, through looking into, in about 5 * 7cm epidermis the blister that differs in size is arranged on the instep, the edge redness, scorching hot pain advises that it uses the present invention unbearably, with preceding blister is punctured, smear the present invention, with back 2 hours scorching hot the alleviating of pain, medication was scalded red and swollen area and is dwindled after 3 days, the red and swollen disappearance, continuous use was fully recovered after 7 days.

Case 3: the king is kind, the man, 55 years old, Wuyi town, Wuyi County, Hebei province east Da Shi people from village, because of accidentally deep fat is spattered on one's body, examine on July 15th, 2004, the scald that its left side wrist and shirtfront have many 0.2～1cm to differ in size, the edge redness has blister, belongs to the I degree and scalds, and the conscious scorching hot pain of patient unbearably.Be coated with the present invention after 1 hour, patient's pain is scorching hot to be alleviated, and continuous use is transference cure after 4 days, is almost recovered after two weeks, and the affected part does not have cicatrix.

Case 4: Wang Yushan, the man, 38 years old, east, Wuyi, Wuyi County town Da Shi people from village, because of the tractor water tank scald shank that breaks, examine on October 4th, 2003, through looking into the scald point many places that its left lower limb knee joint to instep has 3～6cm to differ in size approximately, the edge redness, scald the surface skin mucosa and destroy, blister is arranged, the scorching hot pain of patient unbearably.Be coated with patient's pain, scorching hot alleviating after 1 hour with the present invention, be coated with scorching hot, the pain in 1 week back, pruritus and disappear, the edge, affected part dwindles, 5 week back scald faces take a favorable turn, continuous with 2 week the back fully recover.

Case 5: prosperous entirely, the man, 68 years old, Da Shi people from village behind the town of Wuyi, Wuyi County because of handicapped, pressed left hand on fire coal when stoking accidentally, and going out the indagation patient left hand palm has the mucocutaneous destruction of 5～7cm, belongs to I degree burn, and the scorching hot pain of patient is unbearably.Be coated with that pain is scorching hot after 4 hours alleviates with the present invention, pruritus sx after 2 days, the scorching hot transference cure of 1 week back pain, the back recovery from illness of 3 weeks.

Case 6: Wang Sumiao, the woman, 38 years old, Wuyi, Wuyi County town Du Jia people from village scalded by deep fat when private prosecution is cooked accidentally, looks into the red and swollen blister that face amount has several 1cm to differ in size on it when examining, and patient's pain is unbearably.Be coated with 30 minutes pain behind the present invention and disappear transference cure after 1 day, recovery from illness after 5 days.

The specific embodiment

For further specifying the present invention, be described further below in conjunction with specific embodiment:

Embodiment 1: at first will cleaning also, dried 1Kg Radix Arnebiae (Radix Lithospermi), the 1Kg Pseudobulbus Bletillae (Rhizoma Bletillae), 1.5Kg Radix Et Rhizoma Rhei, 0.7Kg Pericarpium Papaveris, 1Kg Radix Sanguisorbae, Crinis Carbonisatus (Crinis Carbonisatus) 0.3Kg, Borneolum Syntheticum 6g grind to 80～100 orders standby respectively; 1Kg Radix Arnebiae (Radix Lithospermi) after will grinding again, the 1Kg Pseudobulbus Bletillae (Rhizoma Bletillae), 1.5Kg Radix Et Rhizoma Rhei, 0.7Kg Plantula Papaveris, 1Kg Radix Sanguisorbae, Crinis Carbonisatus 0.3Kg mix the back and add in the hot Oleum sesami of 40Kg, fully stir, and endure to crude drug mixture surface and cross the elimination medicinal residues when sallow, treat to add when temperature is reduced to 50～70 ℃ the 6g Borneolum Syntheticum after grinding, fully stir, receive cream, promptly make the putty-type medicine of treatment burn and scald of the present invention.Also available other vegetable oil of above-mentioned Oleum sesami replaces, and as Oleum Arachidis hypogaeae semen, Semen Allii Tuberosi wet goods, but preferred Oleum sesami also can adopt glycerol or vaseline.

Other embodiment difference from Example 1 sees the following form:

Unit: (kg)

Using method of the present invention is every day 2～4 times.

The present invention is to the careful usefulness of Oleum sesami skin allergy person.

Claims (3)

1. medicine for the treatment of burn and scald is characterized in that it is formulated by the crude drug of following portions by weight ratio:

Radix Arnebiae (Radix Lithospermi) 8～15 Pseudobulbus Bletillae (Rhizoma Bletillae)s 8～15 Radix Et Rhizoma Rhei 10～20

Pericarpium Papaveris 4～10 Radix Sanguisorbaes 6～15 Crinis Carbonisatus 2～4

Borneolum Syntheticum 0.03～0.1 Oleum sesami 300～500.

2. the medicine of treatment burn and scald according to claim 1 is characterized in that described each raw material weight umber ratio is:

Radix Arnebiae (Radix Lithospermi) 10～12 Pseudobulbus Bletillae (Rhizoma Bletillae)s 10～12 Radix Et Rhizoma Rhei 12～16

Pericarpium Papaveris 6～8 Radix Sanguisorbaes 8～12 Crinis Carbonisatus 2～4

Borneolum Syntheticum 0.05～0.08 Oleum sesami 350～450.

3. the medicine of treatment burn and scald according to claim 1 and 2 is characterized in that described each raw material weight umber ratio is:

Radix Arnebiae (Radix Lithospermi) 10 Pseudobulbus Bletillae (Rhizoma Bletillae)s 10 Radix Et Rhizoma Rhei 15

Pericarpium Papaveris 7 Radix Sanguisorbaes 10 Crinis Carbonisatus 3

Borneolum Syntheticum 0.06 Oleum sesami 400.