CN100346811C - Capsules of astrogalus, wolfberry fruit and schisandra fruit and their making method - Google Patents

Abstract

The present invention relates to a capsule of astrogalus, wolfberry fruit and schisandra fruit and a preparation process thereof. The present invention provides a medicine for patients with masculine sterility and a production method thereof. The formula of the Chinese medicinal preparation is composed of fifteen traditional Chinese medicines of milkvetch root, barbary wolfberry fruit, Chinese magnolivine fruit, etc. The present invention has the preparation process for preparing the capsule of astrogalus, wolfberry fruit and schisandra fruit that four medicines are powdered into powder, eleven medicines are decocted, extracted and mixed with softwood, and the mixture is granulated and is filled in capsules. The capsule of astrogalus, wolfberry fruit and schisandra fruit has the advantages of scientific capsule formulation, easy preparation process, convenient oral administration and has the obvious therapeutic effect on functionality aspermatism, less spermia, necrozoospermia, excessive abnormal spermia and psychological masculine sterility.

Description

Capsule of astrogalus, wolfberry fruit and schisandra fruit and preparation technology thereof

Affiliated technical field

Capsule of astrogalus, wolfberry fruit and schisandra fruit and preparation technology thereof belong to medicine and the preparation technology thereof who treats male sterility, relate in particular to the Chinese medicine preparation and the preparation technology thereof that too much reach psychological sterility disease with Chinese prescription treatment function of male azoospermia, few essence, necrospermia and teratospermia.

Background technology

Male infertility is to live together after Mr. and Mrs marry more than 1 year, sexual life is normal, do not adopt contraceptives and do not become pregnant, its reason belongs to bridegroom's or husband's side person, differential diagnosis in tcm is divided into and accumulates card, syndrome of stagnation of liver qi and blood stasis in syndrome of deficiency of kidney-YANG, syndrome of deficiency of kidney yin, the phlegm-damp, the cause of disease be azoospermia, few smart, necrospermia and teratospermia too much and psychological sterile, the patient has that libido is indifferent, lethargy, complexion light are white, fear of cold happiness temperature, soreness of the waist and knees, dizziness and tinnitus, bodily form obesity, limbs are sleepy, Mental fatigue is breathed hard, easypro, the multiple class symptom of fidgety irritability uncomfortable in chest.Though patient crowd is little, be polymorphic type, a class is because of five kinds of strain and seven kinds of impairment, and body is thin unable, the no oligospermia essence of suffering from a deficiency of the kidney; One class is that bodily form obesity, lipid disorders, smart arteries and veins are obstructed, necrospermia and teratospermia are too much, a class is the hepatic and renal YIN deficiency, emission, vertigo and tinnitus, impotence and premature ejaculation again, cause few smart necrospermia, also having a class is that mental pressure is big, normal restlessness of asrhenia type and insomnia or palpitation with fear insomnia, sexual life is unable, one-tenth impotence and seminal emission of a specified duration, takes off meticulously tired, Mental fatigue and breathes hard, causes psychological sterile.Above-mentioned multiclass is in the single generation of stadium just, normal easy comprehensive generation after the prolonged illness, and market is many based on Yang invigorating medicine, and it is very little that functional azoospermia, few essence, necrospermia and teratospermia are too much reached psychological infertile patients curative effect, and market lacks the active drug of comprehensive therapy man infertility.

Summary of the invention

The objective of the invention is: giving to suffer from because of functional azoospermia, few essence, necrospermia and teratospermia too much reach psychological male infertility patient provides scientific formulation, can reach the kidney warming spermatogenesis, strong liver annealing, blood circulation invigorating efficacies, effectively treat the compound Chinese medicinal preparation of male infertility, and have no side effect, evident in efficacy, production technology is easy, and is with low cost, convenient oral.

In order to realize the foregoing invention purpose, the technical solution adopted in the present invention is: capsule of astrogalus, wolfberry fruit and schisandra fruit is according to the main etiology and pathogenesis of male infertility, with the kidney warming spermatogenesis, strong liver annealing, blood circulation promoting and blood stasis dispelling is principle of treatment, the crude drug total amount is 750 grams in the prescription, is made up of the Radix Astragali, the Rhizoma Anemarrhenae, each 60 gram of Herba Epimedii, Fructus Lycii, Fructus Schisandrae Chinensis, Semen Plantaginis, Semen Cuscutae, Concha Ostreae, Os Draconis, Radix Cyathulae, Radix Dipsaci, Radix Polygoni Multiflori, each 50 gram of Radix Angelicae Sinensis, Rhizoma Coptidis 30 grams, Actinolitum 40 grams.The preparation technology of capsule of astrogalus, wolfberry fruit and schisandra fruit is divided into 4 flavor medicine powder process, 11 flavor medicines decoct extractum, soft material is mixed, granulate, dress capsule five road technologies, get Concha Ostreae earlier, Os Draconis, Actinolitum, Rhizoma Coptidis four flavor Chinese crude drugs are dried below 80 ℃ and were pulverized 80 mesh sieves to be mixed into the fine powder medicine standby, get the Radix Astragali again, Fructus Lycii, Fructus Schisandrae Chinensis, Semen Plantaginis, Semen Cuscutae, Radix Cyathulae, Radix Dipsaci, Radix Polygoni Multiflori, Radix Angelicae Sinensis, the Rhizoma Anemarrhenae, Herba Epimedii ten Chinese crude drug simply decocts secondary, add for the first time 10 times of amounts of water, decocted 1.5 hours, add for the second time 6 times of amounts of water, decocted 1 hour, merging decoction liquor filters, filtrate is concentrated into the extractum of relative density 1.30 (60 ℃), make soft material with standby fine powder medicine mixing, crossing 14 order nylon mesh granulates, oven dry is sub-packed in No. 1 capsule and gets patent medicine below 80 ℃.Chinese medicine thinks that male infertility is many because of due to internal injury overstrain, palpitation with fear insomnia, the hepatic and renal YIN deficiency, impotence and seminal emission, emission, penis swell and ache, modern Chinese medicine research confirms: the Radix Astragali has benefiting qi and raising yang, help the gas bone strengthening, put on flesh and enrich blood, the complement sun, control the impairment caused by overstrain effect, the oral administration astragalus essence can significantly reduce urine albumen amount, alleviates nephropathy; Fructus Lycii has nourishing the liver, nourishing kidney, the lung moistening and production of body fluid promoting, nourishing the essence and strengthening QI, the effect of calming the nerves makes eye bright; Fructus Schisandrae Chinensis has astringent or styptic treatment for spontaneous sweating, the supplementing QI for promoting the production of body fluid of convergence, mind tranquilizing and the heart calming, all asthenia of benefit, the smart effect of beneficial man; Semen Plantaginis has clearing away heat and promoting diuresis, makes eye bright and eliminate the phlegm, support lung reinforcing YIN-essence benefit essence, has made us sub-effect; Semen Cuscutae has the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, control man's cold caused by deficiency, sperm adding and marrow healthing, go the lumbago knee joint cold, mend five kinds of strain and seven kinds of impairment, control ghost and hand over and let out smart effect; Concha Ostreae has suppressing the hyperactive liver and subsiding YANG, tranquilizing mind, control the man passes out semen that asthenia wearyly decreases, the kidney invigorating healthy energy effect; Os Draconis have tranquilizing mind, suppressing the hyperactive liver and subsiding YANG, kidney tonifying is relieving convulsion, end dream lets out essence, the controlling nocturnal emission with astringent drugs effect of allaying excitement; Radix Cyathulae has blood circulation promoting and blood stasis dispelling, expelling wind and removing dampness, inducing diuresis for treating stranguria syndrome effect; Radix Dipsaci has invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating, urine reducing, the smart effect of stopping leak; Radix Polygoni Multiflori has nourishing the blood and yin, long energy, beneficial marrow, clothes have made us sub-effect for a long time; Radix Angelicae Sinensis has the effect of enriching blood, invigorate blood circulation; The Rhizoma Anemarrhenae have heat clearing away secrete fire, nourshing Yin and drynsessmoistening prescription, profit cardiopulmonary, spasmolytic are throbbed with fear, purte the white, kidney nourishing water effect; Rhizoma Coptidis has clearing away heat-fire, dampness detoxifcation, controls five kinds of strain and seven kinds of impairment, goes the stagnant blood of thinking, diabetes with polydipsia as the prominent symptom to amass burnt fiery effect; Herba Epimedii has kidney invigorating and YANG supporting, strengthening the tendons and bones, benefit waist gas, heart tonifying power, the smart effect of supporing yang benefit; Actinolitum has the right kidney gate of vitality of benefit, controls smart weary, the cold numbness effect of waist knee joint of impotence.Select above-mentioned prescription medicine compatibility for use, it is etiology and pathogenesis according to the syndrome of polymorphic type man infertility, with the kidney warming spermatogenesis, strong liver annealing, blood circulation promoting and blood stasis dispelling and the epitheliosis of promotion testicular spermatogenic, adjusting gonad endocrine function and property nerve excitability is principle of treatment, play altogether that strong body spermatogenesis, sperm adding and marrow healthing, controlling nocturnal emission with astringent drugs are allayed excitement, the merit of kidney invigorating and YANG supporting, effectively treat man's infertility.

Capsule of astrogalus, wolfberry fruit and schisandra fruit cures mainly relevant Pharmacodynamic test of active extract with function and confirms in preclinical study, yellow sub imperial capsule has significant curative effect to comprehensive man's infertility, and to recommend oral dose be three times on the one, and each 4,3 months is a course of treatment.

The invention has the beneficial effects as follows: scientific formulation is reasonable, by the complementation of many medicine effects, capsule of astrogalus, wolfberry fruit and schisandra fruit has the kidney warming spermatogenesis, strong liver annealing, blood circulation promoting and blood stasis dispelling and sexual function improvement effect, can effectively treat because of functional azoospermia, few smart, necrospermia and teratospermia too much and psychological comprehensive man's infertility such as sterile, and have no side effect, production technology is easy, and is with low cost, convenient oral.

Specific embodiments:

1, the capsule of astrogalus, wolfberry fruit and schisandra fruit prescription is made up of 15 kinds of Chinese crude drugs, the Radix Astragali, the Rhizoma Anemarrhenae, each 60 gram of Herba Epimedii three flavor Chinese crude drugs in the prescription, Fructus Lycii, Fructus Schisandrae Chinensis, Semen Plantaginis, Semen Cuscutae, Concha Ostreae, Os Draconis, Radix Cyathulae, Radix Dipsaci, Radix Polygoni Multiflori, each 50 gram of Radix Angelicae Sinensis ten flavor Chinese crude drugs, Rhizoma Coptidis 30 grams, Actinolitum 40 grams, total amount is totally 750 grams, it is standby that wherein Semen Cuscutae, Semen Plantaginis, Concha Ostreae are got the weighing of parch prepared slices of Chinese crude drugs difference, it is standby that Actinolitum is got the weighing of the calcine prepared slices of Chinese crude drugs, and weighing is standby respectively behind all the other Chinese crude drug enchashment row prepared slices of Chinese crude drugs roguing well sifteds.

2, yellow sub-LONGMU oyster capsules preparation technique:

1. Concha Ostreae, Os Draconis, Actinolitum, Rhizoma Coptidis four flavor Chinese crude drugs were pulverized 80 sieves after 80 ℃ of following temperature oven dry respectively, it is standby to be mixed into the fine powder medicine.

2. decoct with water secondary after all the other standby tcm and herbal slices being mixed, add 10 times of water gagings for the first time, decocted 1.5 hours, add 6 times of water gagings for the second time, decocted 1 hour, collecting decoction filters, and filtrate is concentrated into the extractum of relative density 1.30 (60 ℃).

3. extractum and standby fine powder medicine are mixed into soft material, cross 14 order nylon mesh and granulate, temperature drying below 80 ℃ divides No. 1 capsule of packing into to get patent medicine.

Claims (2)

1, a kind of capsule of astrogalus, wolfberry fruit and schisandra fruit, it is characterized in that: the crude drug total amount is 750 grams in the prescription, is made up of the Radix Astragali, the Rhizoma Anemarrhenae, each 60 gram of Herba Epimedii, Fructus Lycii, Fructus Schisandrae Chinensis, Semen Plantaginis, Semen Cuscutae, Concha Ostreae, Os Draconis, Radix Cyathulae, Radix Dipsaci, Radix Polygoni Multiflori, each 50 gram of Radix Angelicae Sinensis, Rhizoma Coptidis 30 grams, Actinolitum 40 grams.

2, capsule of astrogalus, wolfberry fruit and schisandra fruit preparation technology according to claim 1, it is characterized in that: get Concha Ostreae earlier, Os Draconis, Actinolitum, pulverizing 80 mesh sieves after Rhizoma Coptidis four flavor raw materials are dried below 80 ℃, to be mixed into the fine powder medicine standby, get the Radix Astragali again, Fructus Lycii, Fructus Schisandrae Chinensis, Semen Plantaginis, Semen Cuscutae, Radix Cyathulae, Radix Dipsaci, Radix Polygoni Multiflori, Radix Angelicae Sinensis, the Rhizoma Anemarrhenae, Herba Epimedii ten Chinese crude drug simply decocts secondary, add for the first time 10 times of amounts of water, decocted 1.5 hours, add for the second time 6 times of amounts of water, decocted 1 hour, merging decoction liquor filters, relative density was 1.30 extractum when filtrate was concentrated into 60 ℃, make soft material with standby fine powder medicine mixing, crossing 14 order nylon mesh granulates, oven dry is sub-packed in No. 1 capsule and gets patent medicine below 80 ℃.